Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays

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Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays is …
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P6179Dimensions Publication ID1011006064
P356DOI10.1186/GB-2002-3-8-RESEARCH0042
P932PMC publication ID126236
P698PubMed publication ID12186649
P5875ResearchGate publication ID11200243

P50authorCharles AuffrayQ2958434
Eric EvenoQ90561741
Charles DecraeneQ125318471
P2093author name stringMerle Ruberg
Jean Mariani
Bernard Brugg
Fariza Tahi
Geneviève Pietu
Christiane Matingou
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Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signalsQ24554400
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
Construction and characterization of a normalized cDNA libraryQ24563649
Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activationQ24648337
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arraysQ24802601
Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F functionQ28137829
Cloning and characterization of rat BAT3 cDNAQ28138499
The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent mannerQ28251520
Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosisQ28274211
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A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2Q28279758
H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancerQ28282874
Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease ConsortiumQ28288921
Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteinsQ28291920
Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reactionQ28293156
Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and AktQ28297002
Increased expression of rat ribosomal protein L4 mRNA in 5-azacytidine-treated PC12 cells prior to apoptosisQ28569566
Cloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylaseQ28571696
Mannose 6-phosphate/insulin-like growth factor II receptor mediates the growth-inhibitory effects of retinoidsQ28579660
Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulationQ28589590
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PolyaminesQ29615154
Caspase structure, proteolytic substrates, and function during apoptotic cell deathQ33782479
Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53Q33957610
The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential.Q34301155
Expression of nma, a novel gene, inversely correlates with the metastatic potential of human melanoma cell lines and xenograftsQ34377932
Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA arrayQ34399446
Characterization of the promoter for the human long pentraxin PTX3. Role of NF-kappaB in tumor necrosis factor-alpha and interleukin-1beta regulationQ34420055
Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3.Q34462144
Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesisQ36300832
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The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.Q36786465
ERM, a PEA3 subfamily of Ets transcription factors, can cooperate with c-JunQ38290551
The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesisQ38315886
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalingQ40751632
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.Q40883173
The ras suppressor, RSU-1, enhances nerve growth factor-induced differentiation of PC12 cells and induces p21CIP expressionQ40931742
Overexpression of Akt (protein kinase B) confers protection against apoptosis and prevents formation of ceramide in response to pro-apoptotic stimuliQ40932374
CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramideQ40962723
Anti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation.Q40976760
The in vitro neuronal toxicity of pentraxins associated with Alzheimer's disease brain lesionsQ40990749
Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G proteinQ41097795
Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cellsQ41100173
Mitogen-activated protein kinase cascades and regulation of gene expressionQ41102936
Role of ceramide in stimulation of the transcription of cytosolic phospholipase A2 and cyclooxygenase 2.Q41213832
Tumor necrosis factor-alpha induces the 85-kDa cytosolic phospholipase A2 gene expression in human bronchial epithelial cellsQ41229811
Functions of ceramide in coordinating cellular responses to stressQ41243489
Signal transduction in cellular senescence.Q41377547
Signal transduction of stress via ceramideQ41841345
Bipotential roles of ceramide in the growth of hippocampal neurons: promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent mannersQ42453723
Methylmalonyl-CoA mutase induction by cerebral ischemia and neurotoxicity of the mitochondrial toxin methylmalonic acid.Q42527268
Acetylation of decarboxylated S-adenosylmethionine by mammalian cellsQ42812910
Is the AMPA receptor subunit GluR2 mRNA an early indicator of cell fate after ischemia? A quantitative single cell RT-PCR studyQ43540608
Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylationQ43650949
H-cadherin expression inhibits in vitro invasiveness and tumor formation in vivoQ45888355
Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts.Q45972174
Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells.Q47903492
Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells.Q47903738
Regulation of inhibitory pathways of the interleukin-1 systemQ47966652
Mechanisms of apoptosis in PC12 cells irreversibly differentiated with nerve growth factor and cyclic AMP.Q48271646
Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease.Q48610181
Reverse transcription in the presence of dideoxynucleotides to increase the sensitivity of expression monitoring with cDNA arraysQ48757341
C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer's diseaseQ48796828
Somatostatin-positive neurons in the different parts of the brain in normal aging and Alzheimer's disease.Q48867445
Ceramide induces apoptosis in cultured mesencephalic neuronsQ49156263
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.Q54062670
BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1Q59123101
c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells.Q64967336
Activation of Programmed Cell Death by Recombinant Human Tumor Necrosis Factor Plus Topoisomerase II - Targeted Drugs in L929 Tumor CellsQ67913308
The c-ets-1 proto-oncogene is a new early-response gene differentially regulated by cytokines and growth factors in human fibroblastsQ70993462
Role of ceramide-activated protein phosphatase in ceramide-mediated signal transductionQ72068815
Synergistic differentiation by chronic exposure to cyclic AMP and nerve growth factor renders rat phaeochromocytoma PC12 cells totally dependent upon trophic support for survivalQ72254061
Ceramide induces apoptosis in PC12 cellsQ73025799
Dissociation of apoptosis and activation of IL-1beta-converting enzyme/Ced-3 proteases by ALG-2 and the truncated Alzheimer's gene ALG-3Q73369960
Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathwayQ73459589
SMN oligomerization defect correlates with spinal muscular atrophy severityQ74557706
P4510describes a project that usesImageQuantQ112270642
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
ceramidesQ424213
P304page(s)RESEARCH0042
P577publication date2002-07-31
P1433published inGenome BiologyQ5533480
P1476titleIdentification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
P478volume3

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cites work (P2860)
Q42546279Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins
Q64928333HN1L is essential for cell growth and survival during nucleopolyhedrovirus infection in silkworm, Bombyx mori.
Q33540468Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.
Q24802601Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
Q36636261Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program.
Q24321570Microcephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitors
Q41847718Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies
Q83198040Parkin modulates gene expression in control and ceramide-treated PC12 cells
Q90377163The CLN3 gene and protein: What we know
Q92861494The Role of Neuronal Pentraxin 2 (NP2) in Regulating Glutamatergic Signaling and Neuropathology

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