The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.

scientific article published on January 1992

The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1992PNAS...89..539R
P356DOI10.1073/PNAS.89.2.539
P932PMC publication ID48274
P698PubMed publication ID1346232
P5875ResearchGate publication ID21809942

P50authorAnsuman ChattopadhyayQ57068908
P2093author name stringA Chakraborty
B Datta
M K Ray
N K Gupta
S Meza-Keuthen
P2860cites workTranslational control in mammalian cellsQ28295830
Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cellsQ33556101
Roles of a 67-kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysateQ33572837
A heat-sensitive inhibitor in poliovirus-infected cells which selectively blocks phosphorylation of the alpha subunit of eucaryotic initiation factor 2 by the double-stranded RNA-activated protein kinaseQ36872812
Activation of double-stranded RNA-activated protein kinase in HeLa cells after poliovirus infection does not result in increased phosphorylation of eucaryotic initiation factor-2Q36888512
Interferon-mediated, double-stranded RNA-dependent protein kinase is inhibited in extracts from vaccinia virus-infected cellsQ36914505
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infectionQ37522288
Purification and visualization of native spliceosomesQ43415010
Glycosylation of eukaryotic peptide chain initiation factor 2 (eIF-2)-associated 67-kDa polypeptide (p67) and its possible role in the inhibition of eIF-2 kinase-catalyzed phosphorylation of the eIF-2 alpha-subunitQ43464649
Regulation of initiation factors during translational repression caused by serum depletion. Covalent modificationQ44780203
Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinaseQ45795607
Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.Q45844438
Roles of eIF-2 and eIF-2-associated proteins in regulation of protein synthesis during growth of animal cells in cultureQ68086656
Identification of spectrin-related peptides associated with the reticulocyte heme-controlled alpha subunit of eukaryotic translational initiation factor 2 kinase and of Mr 95,000 peptide that appears to be the catalytic subunitQ69060965
Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesisQ69424697
Vaccinia specific kinase inhibitory factor prevents translational inhibition by double-stranded RNA in rabbit reticulocyte lysateQ69613112
Tumor-promoting phorbol esters stimulate the phosphorylation of ribosomal protein S6 in quiescent Reuber H35 hepatoma cellsQ70185324
Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translationQ70382248
The effects of amino acid starvation on regulation of polypeptide chain initiation in Ehrlich ascites tumor cellsQ71133181
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)539-543
P577publication date1992-01-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells
P478volume89

Reverse relations

cites work (P2860)
Q47959032A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila
Q77365588Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells
Q57220523An infB-Homolog in Sulfolobus acidocaldarius
Q34010093Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.
Q48129478Cell death, calcium mobilization, and immunostaining for phosphorylated eukaryotic initiation factor 2-alpha (eIF2alpha) in neuronally differentiated NB-104 cells: arachidonate and radical-mediated injury mechanisms
Q44193512Characterization of the O-GlcNAc protein modification in Xenopus laevis oocyte during oogenesis and progesterone-stimulated maturation
Q48279233Characterization of the eIF2-associated protein p67 during brain ischemia and reperfusion
Q36859055Cloning and characterization of the promoter region of a gene encoding a 67-kDa glycoprotein
Q35804446Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease
Q92157098Fumagillin, a Mycotoxin of Aspergillus fumigatus: Biosynthesis, Biological Activities, Detection, and Applications
Q45244954Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis
Q40022115Identification of genes deregulated during serum-free medium adaptation of a Burkitt's lymphoma cell line
Q24802601Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
Q34557941Impact of the N-terminal amino acid on targeted protein degradation
Q34878502Localization and function of a eukaryotic-initiation-factor-2-associated 67-kDa glycoprotein
Q33869388MAPs and POEP of the roads from prokaryotic to eukaryotic kingdoms
Q34127108Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4.
Q48795696Methionine aminopeptidase II: A molecular chaperone for sarcoplasmic reticulum calcium ATPase
Q24685718Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity
Q24651202Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2
Q34462072Nuclear and cytoplasmic glycosylation.
Q33783725O-GlcNAc and the control of gene expression
Q33907013O-GlcNAc cycling enzymes associate with the translational machinery and modify core ribosomal proteins
Q33601659PKR, apoptosis and cancer
Q52547681Phosphorylation of plant eukaryotic initiation factor-2 by the plant-encoded double-stranded RNA-dependent protein kinase, pPKR, and inhibition of protein synthesis in vitro.
Q33922404Post-transcriptional regulation of androgen receptor mRNA by an ErbB3 binding protein 1 in prostate cancer
Q41384666Regulation of an eukaryotic initiation factor-2 (eIF-2) associated 67 kDa glycoprotein (p67) and its requirement in protein synthesis.
Q72827465Regulation of eukaryotic protein synthesis by protein kinases that phosphorylate initiation factor eIF-2
Q35116530Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold
Q33857472Structure and function of the methionine aminopeptidases
Q79953501The N-terminal lysine residue-rich domain II and the 340-430 amino acid segment of eukaryotic initiation factor 2-associated glycoprotein p67 are the binding sites for the gamma-subunit of eIF2
Q24684014The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
Q24646329The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase
Q73316454p67 transcription regulates translation in serum-starved and mitogen-activated KRC-7 cells

Search more.