PTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathway

scientific article

PTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELLSIG.2008.07.020
P698PubMed publication ID18771726

P2093author name stringLu Wang
Ting Li
Taiping Shi
Yanfei Zhang
Dalong Ma
Qihua He
Wenling Han
Yingmei Zhang
Chuanfei Yu
Quansheng Song
Bingfeng Lv
P2860cites workNegative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTPQ24321559
Bcl-2 targets the protein kinase Raf-1 to mitochondriaQ24321753
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserineQ24322674
The role of protein tyrosine phosphatase 1B in Ras signalingQ24622106
Large-scale mapping of human protein-protein interactions by mass spectrometryQ24670192
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand bindingQ27619633
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathwayQ28204706
14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domainQ28246442
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organizationQ28278217
The MAPK signaling cascadeQ28292599
Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK bindingQ28648013
14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylationQ29041812
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesQ29614338
The RAF proteins take centre stageQ29620153
Imaging of cell migrationQ30477789
14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activityQ33292430
How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesisQ34120299
Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinaseQ34407252
14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylationQ34439988
Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosisQ34544761
Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasisQ34607187
Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activationsQ34991305
Unlocking the code of 14-3-3.Q35748302
Regulation of tumor cell motility by ERK mitogen-activated protein kinasesQ36014066
Negative regulation of Raf-1 by phosphorylation of serine 621.Q40019933
CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell linesQ40073739
Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytesQ40158832
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migrationQ40393756
Regulation of Raf-1 by direct feedback phosphorylation.Q40467820
Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase associationQ40757992
Bcr and Raf form a complex in vivo via 14-3-3 proteinsQ40789573
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 familyQ41436352
The novel protein PTPIP51 exhibits tissue- and cell-specific expressionQ42472048
Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.Q42800762
14-3-3 dimers probe the assembly status of multimeric membrane proteinsQ44406301
Threshold levels of ERK activation for chemotactic migration differ for NGF and EGF in rat pheochromocytoma PC12 cellsQ46479843
The RAF family: an expanding network of post-translational controls and protein-protein interactions.Q47823131
Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.Q53335960
A brake becomes an accelerator: PTP1B--a new therapeutic target for breast cancer.Q54383166
Roles for the protein tyrosine phosphatase SHP-2 in cytoskeletal organization, cell adhesion and cell migration revealed by overexpression of a dominant negative mutantQ73379065
The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activationQ73561161
Expression of the novel protein PTPIP51 in rat liver: an immunohistochemical studyQ80435058
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectcell morphologyQ66568582
P304page(s)2208-20
P577publication date2008-12-01
P1433published inCellular SignallingQ1524097
P1476titlePTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathway
P478volume20

Reverse relations

cites work (P2860)
Q38654834Altered Protein Interactions of the Endogenous Interactome of PTPIP51 towards MAPK Signaling
Q37505664Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51.
Q64058529Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin
Q34915802Differentiation-dependent PTPIP51 expression in human skeletal muscle cell culture
Q58709253Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells
Q43257781Expression profile of PTPIP51 in mouse brain
Q92502754IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration
Q33649607Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression
Q38979223Orchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51).
Q34271712PTPIP51 in protein interactions: regulation and in situ interacting partners
Q83297453PTPIP51 interaction with PTP1B and 14-3-3β in adipose tissue of insulin-resistant mice
Q38888799PTPIP51 levels in glioblastoma cells depend on inhibition of the EGF-receptor.
Q24338749PTPIP51-a myeloid lineage specific protein interacts with PTP1B in neutrophil granulocytes
Q36711714PTPIP51: a new interaction partner of the insulin receptor and PKA in adipose tissue
Q35833989PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway
Q30400364Protein tyrosine phosphatase interacting protein 51--a jack-of-all-trades protein
Q58581282The Importance of the Right Framework: Mitogen-Activated Protein Kinase Pathway and the Scaffolding Protein PTPIP51
Q60958881The Interface Between ER and Mitochondria: Molecular Compositions and Functions
Q50700672The overexpression of Rabl3 is associated with pathogenesis and clinicopathologic variables in hepatocellular carcinoma.
Q24298739VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

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