Orchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51).

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Orchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51). is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1037143418
P356DOI10.1007/S00441-016-2508-5
P698PubMed publication ID27734150

P2093author name stringAlexander Brobeil
Monika Wimmer
Stefan Gattenlöhner
Eric Dietel
P2860cites workA novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumorsQ24293435
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasisQ24298739
Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochoreQ24305358
PTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathwayQ24310359
A large set of estrogen receptor β-interacting proteins identified by tandem affinity purification in hormone-responsive human breast cancer cell nucleiQ24319992
PTPIP51-a myeloid lineage specific protein interacts with PTP1B in neutrophil granulocytesQ24338749
Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiologyQ24634012
Large-scale mapping of human protein-protein interactions by mass spectrometryQ24670192
There's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative DiseasesQ26768635
Non-Canonical Hh Signaling in Cancer-Current Understanding and Future DirectionsQ26783611
Direct and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksQ26784027
Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer TherapyQ26797284
Rho GTPases in cell biologyQ27860969
Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascadesQ28260870
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organizationQ28278217
Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activationQ28286802
Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factorsQ28475319
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarityQ28568803
p38 MAP-kinases pathway regulation, function and role in human diseasesQ29616303
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1Q29618389
Signaling networks that regulate cell migrationQ30278918
Chronic high fat diet induces cardiac hypertrophy and fibrosis in miceQ30299931
Protein tyrosine phosphatase interacting protein 51--a jack-of-all-trades proteinQ30400364
Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancersQ30412090
Protein architecture of the human kinetochore microtubule attachment siteQ30436130
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.Q30440717
The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore-microtubule attachment in mitosisQ30498704
EGF-induced centrosome separation promotes mitotic progression and cell survivalQ30573126
Genome-scale RNAi profiling of cell division in human tissue culture cellsQ30836392
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetesQ31131756
Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle ProgressionQ33649607
Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.Q33731903
GSK3beta: role in therapeutic landscape and development of modulatorsQ33812730
PTPIP51 in protein interactions: regulation and in situ interacting partnersQ34271712
14-3-3 proteins; bringing new definitions to scaffoldingQ34405540
VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activityQ34437633
Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunctionQ34452078
Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosisQ34544761
MAPK signal pathways in the regulation of cell proliferation in mammalian cellsQ34593370
The novel protein PTPIP51 is expressed in human keratinocyte carcinomas and their surrounding stromaQ34881573
Differentiation-dependent PTPIP51 expression in human skeletal muscle cell cultureQ34915802
PTPIP51 mRNA and protein expression in tissue microarrays and promoter methylation of benign prostate hyperplasia and prostate carcinomaQ34998198
Suppression of PTEN expression by NF-kappa B prevents apoptosisQ35544303
PTPIP51—A New RelA-tionship with the NFκB Signaling PathwayQ35833989
NF-κB as potential target in the treatment of melanomaQ35916919
Targeting the Hedgehog signaling pathway in cancer: beyond SmoothenedQ35987233
Regulation of microtubules in cell migrationQ36032502
RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegansQ36274493
Targeting the MAPK-RAS-RAF signaling pathway in cancer therapyQ36278239
PTPIP51: a new interaction partner of the insulin receptor and PKA in adipose tissueQ36711714
The network organization of cancer-associated protein complexes in human tissuesQ36751559
Rapid Detection of Glycogen Synthase Kinase-3 Activity in Mouse Sperm Using Fluorescent Gel Shift ElectrophoresisQ36851927
Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignmentQ36890066
Scaffold proteins and immune-cell signallingQ37357014
Endoplasmic reticulum-mitochondria contacts: function of the junctionQ37417736
Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51.Q37505664
Activation of the hedgehog-signaling pathway in human cancer and the clinical implicationsQ37638143
The NF-kappaB family of transcription factors and its regulationQ37672294
PTP1B: a double agent in metabolism and oncogenesisQ37728307
Non-canonical NF-κB signaling pathwayQ37822660
Formation of protein complexes in crowded environments--from in vitro to in vivoQ38075756
The complexity of NF-κB signaling in inflammation and cancerQ38126565
Analysis of the ERK1,2 transcriptome in mammary epithelial cellsQ38342022
Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic BehaviorQ38544785
Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?Q38570262
ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.Q38775367
GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein MotilityQ38870967
PTPIP51 levels in glioblastoma cells depend on inhibition of the EGF-receptor.Q38888799
Memory and PTPIP51--a new protein in hippocampus and cerebellumQ38929898
ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.Q38988714
The known interactome of PTPIP51 in HaCaT cells—inhibition of kinases and receptorsQ39026639
The protein tyrosine phosphatase interacting protein 51 (PTPIP51) is required for the differentiation of photoreceptors.Q39326679
Ninein is released from the centrosome and moves bi-directionally along microtubulesQ40094163
Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytesQ40158832
GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3β downregulates the signaling pathway and reduces cell proliferationQ40523884
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.Q40571746
Regulation of Raf-Akt Cross-talkQ40727585
Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signalingQ40866028
ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Q40991422
Mitosis-specific negative regulation of epidermal growth factor receptor, triggered by a decrease in ligand binding and dimerization, can be overcome by overexpression of receptorQ42441550
The novel protein PTPIP51 exhibits tissue- and cell-specific expressionQ42472048
The protein kinase KSR interacts with 14-3-3 protein and Raf.Q42801317
Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivoQ43103589
Expression profile of PTPIP51 in mouse brainQ43257781
Sufu recruits GSK3beta for efficient processing of Gli3.Q50336964
Tyrosine phosphorylation and the small GTPase rac cross-talk in regulation of endothelial barrier function.Q50748663
PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia.Q54376438
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)411-423
P577publication date2016-10-12
P1433published inCell and Tissue ResearchQ1524113
P1476titleOrchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51).
P478volume368

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cites work (P2860)
Q38654834Altered Protein Interactions of the Endogenous Interactome of PTPIP51 towards MAPK Signaling
Q58581282The Importance of the Right Framework: Mitogen-Activated Protein Kinase Pathway and the Scaffolding Protein PTPIP51
Q64055266The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity