| scholarly article | Q13442814 |
| P2093 | author name string | Lin F | |
| Worman HJ | |||
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 16321-16326 | |
| P577 | publication date | 1993-08-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C | |
| P478 | volume | 268 |
| Q34242119 | "Laminopathies": a wide spectrum of human diseases |
| Q74128261 | 1H, 13C and 15N resonance assignments of the C-terminal domain of human lamin A/C |
| Q34610236 | A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block |
| Q57068930 | A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks |
| Q28072459 | A Novel Role of Lamins from Genetic Disease to Cancer Biomarkers |
| Q26738818 | A Review of the Giant Protein Titin in Clinical Molecular Diagnostics of Cardiomyopathies |
| Q46244222 | A case of Dunnigan-type familial partial lipodystrophy (FPLD) due to lamin A/C (LMNA) mutations complicated by end-stage renal disease |
| Q24657266 | A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model |
| Q36612092 | A genomics approach in determining nanotopographical effects on MSC phenotype |
| Q34520494 | A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder |
| Q28742161 | A quantitative method for the specific assessment of caspase-6 activity in cell culture |
| Q39297135 | A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies |
| Q30415242 | Abberent expression analysis of LMNA gene in hutchinson-gilford progeria syndrome |
| Q30498939 | Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy |
| Q42200089 | Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature aging |
| Q24811421 | Aging syndrome genes and premature coronary artery disease |
| Q36175286 | Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins. |
| Q54971907 | Alternative mRNA Splicing in the Pathogenesis of Obesity. |
| Q28649959 | Amyloid domains in the cell nucleus controlled by nucleoskeletal protein lamin B1 reveal a new pathway of mercury neurotoxicity |
| Q35175056 | An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. |
| Q52592110 | Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins |
| Q37293792 | Antisense-Based Progerin Downregulation in HGPS-Like Patients' Cells |
| Q35883255 | Are B-type lamins essential in all mammalian cells? |
| Q38174963 | B-type lamins in health and disease |
| Q37885159 | Beyond membrane channelopathies: alternative mechanisms underlying complex human disease |
| Q39452236 | Biochemical and genetic interactions between Drosophila caspases and the proapoptotic genes rpr, hid, and grim |
| Q39297143 | Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins |
| Q24627329 | Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome |
| Q37937377 | Breach of the nuclear lamina during assembly of herpes simplex viruses |
| Q36089832 | Cardiac effects of the c.1583 C→G LMNA mutation in two families with Emery-Dreifuss muscular dystrophy |
| Q34567041 | Cardioembolic stroke related to limb-girdle muscular dystrophy 1B. |
| Q98466373 | Cardiovascular Involvement in Pediatric Laminopathies. Report of Six Patients and Literature Revision |
| Q47340107 | Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations |
| Q92757194 | Cellular and Animal Models of Striated Muscle Laminopathies |
| Q54976812 | Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation. |
| Q35789656 | Collagen expression in fibroblasts with a novel LMNA mutation |
| Q91595016 | Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina |
| Q24292954 | Conformational changes in the nuclear lamina induced by herpes simplex virus type 1 require genes U(L)31 and U(L)34 |
| Q24299991 | Coupling of the nucleus and cytoplasm: role of the LINC complex |
| Q39104972 | Current insights into LMNA cardiomyopathies: Existing models and missing LINCs |
| Q33844504 | DNA damage and lamins |
| Q35357871 | Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms |
| Q33608779 | Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition |
| Q36857698 | Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins |
| Q21284168 | Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress |
| Q24539152 | Different mutations in the LMNA gene cause autosomal dominant and autosomal recessive Emery-Dreifuss muscular dystrophy. |
| Q33966782 | Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice |
| Q38991463 | Diseases of the Nucleoskeleton. |
| Q33687043 | Diseases of the nuclear envelope |
| Q58694537 | Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome |
| Q38256841 | Do lamin A and lamin C have unique roles? |
| Q34122720 | Do lamin B1 and lamin B2 have redundant functions? |
| Q36418867 | Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation |
| Q39590939 | Dynamic properties of meiosis-specific lamin C2 and its impact on nuclear envelope integrity |
| Q33595869 | Dynamics of lamin-A processing following precursor accumulation |
| Q79543221 | Emery-Dreifuss muscular dystrophy |
| Q37323331 | Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin |
| Q60958004 | Epigenetic Regulation of Skin Cells in Natural Aging and Premature Aging Diseases |
| Q42218620 | Epigenetic alterations in muscular disorders |
| Q30480982 | Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha. |
| Q57646299 | Exploring the Crosstalk Between and Splicing Machinery Gene Mutations in Dilated Cardiomyopathy |
| Q90259806 | Expression Patterns and Implications of LaminB1 in Rat Cochleae |
| Q24798448 | Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation |
| Q36232795 | Expression of a mutant lamin A that causes Emery-Dreifuss muscular dystrophy inhibits in vitro differentiation of C2C12 myoblasts |
| Q94445596 | Expression of lamin C2 in mammalian oocytes |
| Q33787727 | Familial partial lipodystrophy and proteinuric renal disease due to a missense c.1045C > T LMNA mutation |
| Q50054188 | Farnesyltransferase inhibitors prevent HIV protease inhibitor (lopinavir/ritonavir)-induced lipodystrophy and metabolic syndrome in mice |
| Q38112645 | From lamins to lamina: a structural perspective |
| Q24657223 | GFAP and its role in Alexander disease |
| Q34416406 | Good news in the nuclear envelope: loss of lamin A might be a gain |
| Q34534986 | HIV protease inhibitors do not cause the accumulation of prelamin A in PBMCs from patients receiving first line therapy: the ANRS EP45 "aging" study |
| Q41602786 | Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis |
| Q38351906 | Herpes simplex virus 2 UL13 protein kinase disrupts nuclear lamins |
| Q35632216 | How do mutations in lamins A and C cause disease? |
| Q39900737 | Identification of a new lamin A/C mutation in a Chinese family affected with atrioventricular block as the prominent phenotype |
| Q38992245 | Implications for Diverse Functions of the LINC Complexes Based on the Structure |
| Q40837071 | Increased Expression of Lamin A/C Correlate with Regions of High Wall Stress in Abdominal Aortic Aneurysms |
| Q37334608 | Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome |
| Q36985669 | Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation |
| Q34252203 | Inner nuclear membrane proteins: impact on human disease |
| Q36262090 | Insertional mutation of the Drosophila nuclear lamin Dm0 gene results in defective nuclear envelopes, clustering of nuclear pore complexes, and accumulation of annulate lamellae |
| Q37961442 | Insights into the differences between the A- and B-type nuclear lamins. |
| Q90356556 | Intermediate filaments in cardiomyopathy |
| Q27329552 | Intracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins |
| Q35015891 | Investigating the purpose of prelamin A processing |
| Q53174609 | Juvenile-onset generalized lipodystrophy due to a novel heterozygous missense LMNA mutation affecting lamin C. |
| Q34558130 | LINC complexes in health and disease |
| Q35232610 | LMNA cardiomyopathy: cell biology and genetics meet clinical medicine. |
| Q43182203 | LMNA gene single nucleotide polymorphisms in dilated cardiomyopathy of Han children |
| Q39181367 | Lamin A/C Cardiomyopathies: Current Understanding and Novel Treatment Strategies |
| Q95818573 | Lamin A/C Cardiomyopathy with E203K Pathogenic Mutation |
| Q35632054 | Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. |
| Q33361579 | Lamin A/C is a risk biomarker in colorectal cancer |
| Q37157993 | Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies |
| Q24564213 | Lamin B1 is required for mouse development and nuclear integrity |
| Q35998585 | Lamin B1 loss is a senescence-associated biomarker. |
| Q28251294 | Laminopathies and the long strange trip from basic cell biology to therapy |
| Q88682388 | Laminopathies; Mutations on single gene and various human genetic diseases |
| Q64881706 | Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease. |
| Q90255557 | Lamins in Lung Cancer: Biomarkers and Key Factors for Disease Progression through miR-9 Regulation? |
| Q24336480 | Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin |
| Q34043263 | Low and High Expressing Alleles of the LMNA Gene: Implications for Laminopathy Disease Development |
| Q28507916 | Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells |
| Q24612380 | Mandibuloacral dysplasia is caused by a mutation in LMNA-encoding lamin A/C |
| Q88640354 | Mechanisms of allelic and clinical heterogeneity of lamin A/C phenotypes |
| Q33895715 | Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics |
| Q55252077 | Mechanotransduction, nuclear architecture and epigenetics in Emery Dreifuss Muscular Dystrophy: tous pour un, un pour tous. |
| Q35954331 | Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death? |
| Q33914338 | Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. |
| Q52562166 | MicroRNAs in hereditary and sporadic premature aging syndromes and other laminopathies |
| Q35748457 | Mislocalization of prelamin A Tyr646Phe mutant to the nuclear pore complex in human embryonic kidney 293 cells |
| Q35738376 | Mitogen-activated protein kinase inhibitor regulation of heart function and fibrosis in cardiomyopathy caused by lamin A/C gene mutation. |
| Q41628207 | Modeling Treatment Response for Lamin A/C Related Dilated Cardiomyopathy in Human Induced Pluripotent Stem Cells. |
| Q42541299 | Modeling nuclear blebs in a nucleoskeleton of independent filament networks |
| Q36576360 | Modeling of lamin A/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells |
| Q36737860 | Modulation of LMNA splicing as a strategy to treat prelamin A diseases. |
| Q24632767 | Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance |
| Q37002317 | Muscle development, regeneration and laminopathies: how lamins or lamina-associated proteins can contribute to muscle development, regeneration and disease. |
| Q34145499 | Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C |
| Q36856331 | Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling. |
| Q24338683 | Myotonic dystrophy protein kinase is critical for nuclear envelope integrity |
| Q37593037 | New Lmna knock-in mice provide a molecular mechanism for the 'segmental aging' in Hutchinson-Gilford progeria syndrome |
| Q42672677 | Non-syndromic cardiac progeria in a patient with the rare pathogenic p.Asp300Asn variant in the LMNA gene |
| Q40964035 | Novel linkage of LMNA Single Nucleotide Polymorphism with Dilated Cardiomyopathy in an Indian case study |
| Q60104000 | Nuclear Lamin Protein C Is Linked to Lineage-Specific, Whole-Cell Mechanical Properties |
| Q89762016 | Nuclear Lamins and Emerin Are Differentially Expressed in Osteosarcoma Cells and Scale with Tumor Aggressiveness |
| Q33856490 | Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer |
| Q41579479 | Nuclear envelope: a new frontier in plant mechanosensing? |
| Q36787496 | Nuclear lamin functions and disease |
| Q34136884 | Nuclear lamins |
| Q37939691 | Nuclear lamins and laminopathies |
| Q34056472 | Nuclear lamins and neurobiology |
| Q28573598 | Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina |
| Q36514069 | Nuclear lamins in the brain - new insights into function and regulation. |
| Q36116300 | Nuclear mechanics in cancer |
| Q57312415 | Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study |
| Q33888878 | Porcine LMNA Is a Positional Candidate Gene Associated with Growth and Fat Deposition |
| Q90171669 | Postnatal Development of Mice with Combined Genetic Depletions of Lamin A/C, Emerin and Lamina-associated Polypeptide 1 |
| Q28391383 | Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases |
| Q34416396 | Prelamin A and lamin A appear to be dispensable in the nuclear lamina |
| Q42941531 | Prelamin A prenylation and the treatment of progeria |
| Q36255795 | Processing of endogenous pre-mRNAs in association with SC-35 domains is gene specific |
| Q36852109 | Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated. |
| Q37981563 | Protein farnesylation and disease |
| Q33996884 | RNAi-based Gene Therapy for Dominant Limb Girdle Muscular Dystrophies |
| Q28077171 | Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathy |
| Q33604405 | Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. |
| Q37106817 | Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells. |
| Q37076783 | Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma |
| Q35787261 | Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. |
| Q24539118 | Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome |
| Q33337126 | Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation |
| Q57492157 | Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to Cardiomyopathies |
| Q33649957 | Role of extracellular matrix signaling cues in modulating cell fate commitment for cardiovascular tissue engineering |
| Q55400232 | SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells. |
| Q33809226 | Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy |
| Q37319021 | Severe mandibuloacral dysplasia caused by novel compound heterozygous ZMPSTE24 mutations in two Japanese siblings |
| Q24648917 | Severe mandibuloacral dysplasia-associated lipodystrophy and progeria in a young girl with a novel homozygous Arg527Cys LMNA mutation |
| Q39469416 | Simian virus 40 induces lamin A/C fluctuations and nuclear envelope deformation during cell entry |
| Q26741163 | Skeletal Muscle Laminopathies: A Review of Clinical and Molecular Features |
| Q28082981 | Skin Disease in Laminopathy-Associated Premature Aging |
| Q50188862 | Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin |
| Q36952227 | Squish and squeeze-the nucleus as a physical barrier during migration in confined environments. |
| Q36455433 | Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy |
| Q35549134 | Subcellular localization of SREBP1 depends on its interaction with the C-terminal region of wild-type and disease related A-type lamins |
| Q36931652 | Targeting Mitogen-Activated Protein Kinase Signaling in Mouse Models of Cardiomyopathy Caused by Lamin A/C Gene Mutations |
| Q59137488 | The Emerging Role of Lamin C as an Important Isoform in Mechanophenotype |
| Q58693707 | The Pathogenesis and Therapies of Striated Muscle Laminopathies |
| Q40456468 | The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908c/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek caucasians. |
| Q64464352 | The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking |
| Q53080649 | The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer. |
| Q90462509 | The functional importance of lamins, actin, myosin, spectrin and the LINC complex in DNA repair |
| Q72861208 | The gene structure of B-type nuclear lamins of Xenopus laevis: implications for the evolution of the vertebrate lamin family |
| Q34189692 | The lamin protein family. |
| Q27006719 | The nuclear envelope: an intriguing focal point for neurogenetic disease |
| Q38065087 | The nuclear lamins: flexibility in function |
| Q53684500 | The renal manifestations of type 4 familial partial lipodystrophy: a case report and review of literature. |
| Q37190360 | The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation. |
| Q41597490 | The structure of lamin filaments in somatic cells as revealed by cryo-electron tomography |
| Q35956784 | Understanding the Roles of Nuclear A- and B-type Lamins in Brain Development |
| Q89179955 | Updated clinical overview on cardiac laminopathies: an electrical and mechanical disease |
| Q64268116 | Vascular smooth muscle cell loss underpins the accelerated atherosclerosis in Hutchinson-Gilford progeria syndrome |
| Q26866395 | Virus strategies for passing the nuclear envelope barrier |
| Q38719212 | What Should the Cardiologist know about Lamin Disease? |
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