Crystallographic insights into sodium-channel modulation by the β4 subunit

scientific article

Crystallographic insights into sodium-channel modulation by the β4 subunit is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..110E5016G
P356DOI10.1073/PNAS.1314557110
P3181OpenCitations bibliographic resource ID1409793
P932PMC publication ID3870679
P698PubMed publication ID24297919
P5875ResearchGate publication ID259115194

P50authorFrank BosmansQ57716615
Frank BosmansQ59662440
John GilchristQ86879333
Filip Van PetegemQ57007381
P2093author name stringSamir Das
P2860cites workbeta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kineticsQ22253235
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NaVβ Subunits Modulate the Inhibition of NaV1.8 by the Analgesic Gating Modifier μO-Conotoxin MrVIBQ35122879
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Differential Expression of Sodium Channel β Subunits in Dorsal Root Ganglion Sensory NeuronsQ35922414
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The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic bindingQ36643487
Co‐expression of NaVβ subunits alters the kinetics of inhibition of voltage‐gated sodium channels by pore‐blocking μ‐conotoxinsQ36709224
Na+ channel-dependent recruitment of Navβ4 to axon initial segments and nodes of RanvierQ36813174
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A novel adhesion molecule in human breast cancer cells: voltage-gated Na+ channel beta1 subunit.Q37183730
A functional null mutation of SCN1B in a patient with Dravet syndromeQ37359854
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Tetraspanin proteins promote multiple cancer stagesQ38186043
Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.Q39166783
Glycosylation of the Sodium Channel β4 Subunit is Developmentally Regulated and Involves in Neuritic DegenerationQ39354416
Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channelsQ39881948
Beta-subunits of voltage-gated sodium channels in human prostate cancer: quantitative in vitro and in vivo analyses of mRNA expression.Q40076549
Isolation and characterisation of three polypeptides with neurotoxic activity from Anemonia sulcataQ40308754
Cloning, localization, and functional expression of sodium channel beta1A subunitsQ40907667
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channelQ41217429
The sodium channel {beta}3-subunit induces multiphasic gating in NaV1.3 and affects fast inactivation via distinct intracellular regionsQ41854535
Mechanism of modulation of single sodium channels from skeletal muscle by the beta 1-subunit from rat brain.Q42605753
Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currentsQ43007333
Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxolQ44104234
Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic miceQ45301710
The correlation between Na+ channel subunits and scorpion toxin-binding sites. A study in rat brain synaptosomes and in brain neurons developing in vitroQ48122301
A homozygous mutation of voltage‐gated sodium channel βI gene SCN1B in a patient with Dravet syndromeQ48297410
Large scale purification of toxins from the venom of the scorpion Androctonus australis HectorQ48403596
Temporal lobe epilepsy and GEFS+ phenotypes associated with SCN1B mutations.Q48404617
Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunitQ48502843
Purification of the main beta-toxin from Tityus serrulatus scorpion venom using high-performance liquid chromatographyQ48562245
A thermoprotective role of the sodium channel β1 subunit is lost with the β1 (C121W) mutationQ48682947
Molecular determinants of beta 1 subunit-induced gating modulation in voltage-dependent Na+ channels.Q48860557
Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunitsQ48906387
Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.Q48934070
Effects of Tityus serrulatus scorpion toxin gamma on voltage-gated Na+ channelsQ48962330
Mutations of the SCN4B-encoded sodium channel β4 subunit in familial atrial fibrillationQ51055937
P433issue51
P407language of work or nameEnglishQ1860
P921main subjectsodiumQ658
regulation of sodium ion transmembrane transporter activityQ14901713
Sodium voltage-gated channel beta subunit 4Q7389191
P304page(s)E5016-24
P577publication date2013-12-02
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCrystallographic insights into sodium-channel modulation by the β4 subunit
P478volume110

Reverse relations

cites work (P2860)
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