The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template

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The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKQ417
P8608Fatcat IDrelease_vlnwb3wxy5fzrapcmq4hermqgm
P3181OpenCitations bibliographic resource ID1499680
P932PMC publication ID2952863
P698PubMed publication ID20484372
P5875ResearchGate publication ID44613160

P50authorBenoit de CrombruggheQ114389868
Hideyo YasudaQ114390207
P2093author name stringChun-do Oh
Françoise Coustry
Sankar N Maity
Takako Hattori
P2860cites workThe new collagen gene COL27A1 contains SOX9-responsive enhancer elementsQ24632793
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9Q28210665
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related geneQ28242642
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9Q28243215
Molecular models for vertebrate limb developmentQ28250564
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouseQ28507337
SOX9 directly regulates the type-II collagen geneQ28512288
Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasiaQ57911323
Dimerization of SOX9 is required for chondrogenesis, but not for sex determinationQ73599679
The Sox9 transcription factor determines glial fate choice in the developing spinal cordQ28512816
Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartmentQ28513589
SOX9 is required for the differentiation of paneth cells in the intestinal epitheliumQ28586813
Sox9 is required for cartilage formationQ28588649
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralizationQ28590890
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6Q28593218
Regulatory mechanisms in the pathways of cartilage and bone formationQ34430805
Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elementsQ34759496
Transcriptional control of chondrocyte fate and differentiationQ36269368
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen geneQ36567842
CBF/NF-Y functions both in nucleosomal disruption and transcription activation of the chromatin-assembled topoisomerase IIalpha promoter. Transcription activation by CBF/NF-Y in chromatin is dependent on the promoter structureQ38297621
The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequencesQ39572483
A Col9a1 enhancer element activated by two interdependent SOX9 dimers.Q40177273
The soluble nuclear fraction, a highly efficient transcription extract from Drosophila embryos.Q40501096
SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6.Q40831754
Highly conserved proximal promoter element harbouring paired Sox9-binding sites contributes to the tissue- and developmental stage-specific activity of the matrilin-1 geneQ42012586
Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9.Q42815953
Potentiation of RNA polymerase II transcription by Gal4-VP16 during but not after DNA replication and chromatin assemblyQ46055907
Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivoQ48010592
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P6216copyright statuscopyrightedQ50423863
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectchromatin remodelingQ5113739
SRY-box transcription factor 9Q21127264
P304page(s)6018-28
P577publication date2010-10-01
P1433published inNucleic Acids ResearchQ135122
P1476titleThe dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template
P478volume38

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cites work (P2860)
Q38729196A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.
Q47302135A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein-Protein Interactions.
Q48222935Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements
Q36022698Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9.
Q34483545Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte
Q36052530L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity
Q42360757Multiple enhancers associated with ACAN suggest highly redundant transcriptional regulation in cartilage
Q90191288Post-translational modification of SOX family proteins: Key biochemical targets in cancer?
Q37111035SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc.
Q89102120SOX9 has distinct regulatory roles in alternative splicing and transcription
Q90321016SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis
Q53229089SOX9 regulates ERBB signalling in pancreatic cancer development.
Q34207443SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters
Q35651336SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains
Q37980884Stüve-Wiedemann syndrome and related bent bone dysplasias

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