SOX9 regulates ERBB signalling in pancreatic cancer development.

scientific article published on 21 October 2014

SOX9 regulates ERBB signalling in pancreatic cancer development. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/GUTJNL-2014-307075
P698PubMed publication ID25336113
P5875ResearchGate publication ID267229119

P50authorIlse RoomanQ83181310
Christine SempouxQ37831494
Marina PajicQ38802477
Mark J. CowleyQ38802512
Sean GrimmondQ38802553
Andrew BiankinQ38802580
Andreia V PinhoQ56482259
Nicola J WaddellQ60503046
Jian-min WuQ82105421
P2093author name stringAmanda Mawson
Patrick Jacquemin
Frédéric P Lemaigre
Marc Giry-Laterrière
Cécile Augereau
Adrien Grimont
Géraldine Van den Steen
P2860cites workERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptorQ22254439
Sex reversal by loss of the C-terminal transactivation domain of human SOX9Q24313415
The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA templateQ24313870
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genesQ24595981
Core signaling pathways in human pancreatic cancers revealed by global genomic analysesQ24606006
Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasiaQ24647433
Genetically engineered mouse models of pancreatic adenocarcinomaQ27002973
A method and server for predicting damaging missense mutationsQ27860835
EGF receptor is required for KRAS-induced pancreatic tumorigenesisQ28584901
SIFT: Predicting amino acid changes that affect protein functionQ29547211
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in miceQ29617045
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouseQ29620396
Identification of SOX9 interaction sites in the genome of chondrocytesQ33559758
Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cellsQ34077845
KOBAS server: a web-based platform for automated annotation and pathway identificationQ34974449
Molecular signatures database (MSigDB) 3.0.Q35019708
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseasesQ35075729
Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancerQ35832274
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiationQ36058628
Quantitation of the effect of ErbB2 on epidermal growth factor receptor binding and dimerizationQ36225710
EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinomaQ36696146
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapyQ37127423
Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2Q37191934
Erbin regulates NRG1 signaling and myelinationQ37224245
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasiaQ37501557
Clinical and molecular characterization of HER2 amplified-pancreatic cancer.Q37690146
Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?Q37897800
New biomarkers and targets in pancreatic cancer and their application to treatmentQ38021692
Chronic pancreatitis: a path to pancreatic cancerQ38131933
Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.Q39337159
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in miceQ40679145
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinomaQ41856856
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration.Q42876632
Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.Q43829038
Herceptin and gemcitabine for metastatic pancreatic cancers that overexpress HER-2/neuQ45174616
The sex-determining factors SRY and SOX9 regulate similar target genes and promote testis cord formation during testicular differentiation.Q46017564
Conditional inactivation of Sox9: a mouse model for campomelic dysplasia.Q52123522
Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis.Q54394742
A direct approach to false discovery ratesQ56622258
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
P304page(s)1790-1799
P577publication date2014-10-21
P1433published inGutQ5621669
P1476titleSOX9 regulates ERBB signalling in pancreatic cancer development
P478volume64

Reverse relations

cites work (P2860)
Q38922230Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
Q37430812Analysis of Important Gene Ontology Terms and Biological Pathways Related to Pancreatic Cancer
Q89285906Are Gastric and Esophageal Metaplasia Relatives? The Case for Barrett's Stemming from SPEM
Q38979853Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells
Q91595228Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma
Q92632442Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity
Q58697838Fibroblast Growth Factor 10 in Pancreas Development and Pancreatic Cancer
Q58790645Genome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy
Q36294213Identification of potential biomarkers to differentially diagnose solid pseudopapillary tumors and pancreatic malignancies via a gene regulatory network
Q55516479Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment.
Q42344431Inhibition of SOX9 may be an effective target for increasing radiosensitivity in gastrointestinal cancer.
Q41592795Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma
Q41070965Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer
Q47246517Luteolin inhibits pancreatitis‑induced acinar‑ductal metaplasia, proliferation and epithelial‑mesenchymal transition of acinar cells.
Q98906859MYEOV increases HES1 expression and promotes pancreatic cancer progression by enhancing SOX9 transactivity
Q55455064MiR-133b targets Sox9 to control pathogenesis and metastasis of breast cancer.
Q46861963MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3.
Q36413411MicroRNA-494 inhibits cell proliferation and invasion of chondrosarcoma cells in vivo and in vitro by directly targeting SOX9.
Q38907393New insights in the development of pancreatic cancer
Q26765235Pancreatic Cancer Genetics
Q90425919Plasticity of differentiated cells in wound repair and tumorigenesis, part I: stomach and pancreas
Q89576002Review and Meta-Analyses of TAAR1 Expression in the Immune System and Cancers
Q47616426SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer
Q92668907SOX9 promotes tumor progression through the axis BMI1-p21CIP
Q38753641Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions
Q37301823Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling
Q39007517Targeting reactive oxygen species in development and progression of pancreatic cancer
Q56967209The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis
Q93092086The Influence of TGF-β3, EGF, and BGN on SOX9 and RUNX2 Expression in Human Chondrogenic Progenitor Cells
Q92091586Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway
Q42052094miR-206 inhibits non small cell lung cancer cell proliferation and invasion by targeting SOX9.

Search more.