Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway

scientific article published on 18 December 2019

Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S13046-019-1470-Y
P932PMC publication ID6921559
P698PubMed publication ID31852504

P2093author name stringYan Yu
Xiaodong Xu
Pengwei Lv
Ke Zong
Yuantin Gu
P2860cites workCancer statistics, 2016Q29547383
Systematic review of outcomes after distal pancreatectomy with coeliac axis resection for locally advanced pancreatic cancer.Q30249609
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathwayQ36214062
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Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?Q37002361
IGF2 mRNA-binding protein 2: biological function and putative role in type 2 diabetesQ37476395
Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to DoxorubicinQ37690896
Local recurrence of pancreatic cancer after primary surgical intervention: how to deal with this devastating scenario?Q37875981
IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.Q40478066
IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1Q41559661
Different clinical presentations of metachronous pulmonary metastases after resection of pancreatic ductal adenocarcinoma: Retrospective study and review of the literatureQ42695251
IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal AdenocarcinomaQ43990089
IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer.Q46256483
Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancerQ47146670
VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival.Q50663650
ELF3 promotes epithelial-mesenchymal transition by protecting ZEB1 from miR-141-3p-mediated silencing in hepatocellular carcinoma.Q52663603
SOX9 regulates ERBB signalling in pancreatic cancer development.Q53229089
MicroRNA-141 inhibits proliferation of gastric cardia adenocarcinoma by targeting MACC1.Q53681668
Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4.Q55517744
CPNE1 is a target of miR-335-5p and plays an important role in the pathogenesis of non-small cell lung cancer.Q55517974
WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDACQ90448068
Regulation of tumor angiogenesis by microRNAs: State of the artQ90709815
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19Q90791080
miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcomaQ90929939
The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic CancerQ91519705
P433issue1
P921main subjectpancreatic cancerQ212961
P304page(s)497
P577publication date2019-12-18
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleUp-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway
P478volume38

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cites work (P2860)
Q94547481Clinical Significance of an m6A Reader Gene, IGF2BP2, in Head and Neck Squamous Cell Carcinoma
Q96231220Identification and validation of m6A RNA methylation regulators with clinical prognostic value in Papillary thyroid cancer
Q98770571Important players in carcinogenesis as potential targets in cancer therapy: an update
Q99551787MicroRNA-23b-3p promotes pancreatic cancer cell tumorigenesis and metastasis via the JAK/PI3K and Akt/NF-κB signaling pathways
Q91790678Modulator-Dependent RBPs Changes Alternative Splicing Outcomes in Kidney Cancer
Q100490609Overview of current targeted therapy in gallbladder cancer

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