Conditional inactivation of Sox9: a mouse model for campomelic dysplasia.

scientific article published in February 2002

Conditional inactivation of Sox9: a mouse model for campomelic dysplasia. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/GENE.10050
P698PubMed publication ID11857796
P5875ResearchGate publication ID246902627

P50authorRudi BallingQ122117
Ralf KistQ52087297
P2093author name stringHeinrich Schrewe
Gerd Scherer
P2860cites workSex reversal by loss of the C-terminal transactivation domain of human SOX9Q24313415
A clinical and genetic study of campomelic dysplasiaQ24517890
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related geneQ28242642
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9Q28243215
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouseQ28507337
Sox9 is required for cartilage formationQ28588649
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralizationQ28590890
Sox9 induces testis development in XX transgenic miceQ28593762
Cre recombinase: The universal reagent for genome tailoringQ29028530
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cellsQ29614542
Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cellsQ34651786
The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux et al in 1971.Q40150521
DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1Q46437257
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos.Q52211686
Conditional Gene Knockout Using Cre RecombinaseQ56114286
P433issue2
P304page(s)121-123
P577publication date2002-02-01
P1433published inGenesisQ5532784
P1476titleConditional inactivation of Sox9: a mouse model for campomelic dysplasia.
P478volume32

Reverse relations

cites work (P2860)
Q43217858A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells.
Q36058628A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation
Q38729196A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.
Q36178697A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.
Q39116755A conditional mouse line for lineage tracing of Sox9 loss-of-function cells using enhanced green fluorescent protein
Q28510770A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
Q36783626A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration
Q35023613Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.
Q37970567Building strong bones: molecular regulation of the osteoblast lineage
Q28508603Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum
Q36629738Development of the endochondral skeleton
Q36522778Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology
Q37822860Disruption of long-distance highly conserved noncoding elements in neurocristopathies
Q34637873Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.
Q34948552Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium
Q35930425Endodermal Wnt signaling is required for tracheal cartilage formation
Q37252020Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation
Q48142493Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development
Q51871790Generation of mice with a novel conditional null allele of the Sox9 gene.
Q31018087Genome duplication, subfunction partitioning, and lineage divergence:Sox9in stickleback and zebrafish
Q30354085Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development.
Q28587480Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme
Q64118016Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual
Q33559758Identification of SOX9 interaction sites in the genome of chondrocytes
Q33878055In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
Q91923062Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation
Q28591815Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9
Q33938801Long-range control of gene expression: emerging mechanisms and disruption in disease
Q37087615Long-range gene control and genetic disease
Q28593346Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse
Q35582565Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall
Q52334245Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells.
Q34506834Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.
Q28506607Reduced sox9 function promotes heart valve calcification phenotypes in vivo
Q37501557Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia
Q42371007SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes
Q37111035SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc.
Q90321016SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis
Q28510325SOX9 is required for maintenance of the pancreatic progenitor cell pool
Q47129673SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.
Q60301844SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis
Q53229089SOX9 regulates ERBB signalling in pancreatic cancer development.
Q34207443SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters
Q34656830SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis
Q42510262Sox9 and Sox8 are required for basal lamina integrity of testis cords and for suppression of FOXL2 during embryonic testis development in mice.
Q37095297Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Q35836851Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes
Q36391544Sox9 in testis determination
Q28591158Sox9 is required for invagination of the otic placode in mice
Q47207460Sox9 is required for notochord maintenance in mice
Q28504526Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development
Q36234048Sox9 is required for prostate development and prostate cancer initiation
Q28585673Sox9 plays multiple roles in the lung epithelium during branching morphogenesis
Q28588362Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
Q28507831Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8
Q27331315The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity.
Q28593218The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
Q34483803The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis
Q33556300Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium
Q42477754Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts

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