review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Joseph Burclaff | Q59684701 |
Jason C Mills | Q88427777 | ||
P2860 | cites work | Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs | Q24519327 |
An immunocytochemical and morphometric study of the rat pancreatic islets | Q24531579 | ||
The origin of pre-neoplastic metaplasia in the stomach: chief cells emerge from the Mist | Q24630749 | ||
Mature chief cells are cryptic progenitors for metaplasia in the stomach | Q24631089 | ||
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity | Q24653476 | ||
The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage. | Q24658509 | ||
Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract | Q26801731 | ||
Dedifferentiation and reprogramming: origins of cancer stem cells | Q26826876 | ||
YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling | Q40989829 | ||
Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands | Q41458995 | ||
Tritiated thymidine autoradiographic study on cellular migration in the gastric gland of the golden hamster | Q41517837 | ||
Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease | Q41737306 | ||
Hedgehog signaling is required for effective regeneration of exocrine pancreas | Q41761890 | ||
Spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia: time for reevaluation of metaplasias and the origins of gastric cancer. | Q41861115 | ||
Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells | Q42026806 | ||
Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation | Q42091306 | ||
Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A. | Q42269245 | ||
The Gastric Epithelium: Slow Starter in the Stem Cell/Lineage Specification Stakes? | Q42389501 | ||
Reversible drug-induced oxyntic atrophy in rats | Q42488660 | ||
Early requirement of Rac1 in a mouse model of pancreatic cancer. | Q42490195 | ||
Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence | Q42573716 | ||
Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells | Q42729081 | ||
K-ras mutations in pancreatic ductal proliferative lesions | Q42753837 | ||
c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis | Q42775601 | ||
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas | Q43826975 | ||
Intestinal stem cell replacement follows a pattern of neutral drift | Q44951523 | ||
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration | Q46376132 | ||
Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression. | Q47111525 | ||
Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach | Q47302381 | ||
Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell | Q47566401 | ||
Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence | Q47786705 | ||
Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach | Q48017785 | ||
A chief source of cancer and repair in stomachs. | Q48192570 | ||
Cell plasticity in epithelial homeostasis and tumorigenesis. | Q48296335 | ||
Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach. | Q48328395 | ||
Metaplastic Cells in the Stomach Arise, Independently of Stem Cells, via Dedifferentiation or Transdifferentiation of Chief Cells | Q49722529 | ||
Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer | Q49788912 | ||
Mature gastric chief cells are not required for the development of metaplasia. | Q49967633 | ||
Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice. | Q50219168 | ||
Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis. | Q50422422 | ||
Cellular reprogramming in skin cancer | Q27027468 | ||
A genetic model for colorectal tumorigenesis | Q27860582 | ||
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors | Q27860937 | ||
Targeting RAS signalling pathways in cancer therapy | Q28201363 | ||
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon | Q28246034 | ||
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells | Q28292190 | ||
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium | Q28300176 | ||
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging. | Q28307731 | ||
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes | Q28307762 | ||
EGF receptor is required for KRAS-induced pancreatic tumorigenesis | Q28584901 | ||
Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia | Q28589628 | ||
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice | Q29617045 | ||
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells | Q29619410 | ||
Cells of origin in cancer | Q29619557 | ||
Heart regeneration in zebrafish | Q29619776 | ||
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse | Q29620396 | ||
Spasmolytic polypeptide expressing metaplasia to preneoplasia in H. felis-infected mice | Q33205595 | ||
Pathobiology of Helicobacter pylori-Induced Gastric Cancer | Q33361550 | ||
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice | Q33604913 | ||
MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice | Q33680759 | ||
Metaplasia in the Stomach Arises From Gastric Chief Cells | Q33714766 | ||
Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus | Q33714773 | ||
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. | Q33858490 | ||
Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling | Q33929630 | ||
The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles | Q33970945 | ||
Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration | Q34025442 | ||
Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras | Q34082522 | ||
The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma. | Q34087033 | ||
Plasticity and reprogramming of differentiated cells in amphibian regeneration | Q34142489 | ||
Gastric epithelial stem cells | Q34154012 | ||
Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice | Q34222321 | ||
Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression | Q34330645 | ||
The multistep nature of cancer | Q34366937 | ||
TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa. | Q34380608 | ||
Cytodifferentiation of the postnatal mouse stomach in normal and Huntingtin-interacting protein 1-related-deficient mice | Q34425956 | ||
Early weaning accelerates the differentiation of mucous neck cells in rat gastric mucosa: possible role of TGFalpha/EGFR. | Q50450228 | ||
A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach. | Q50455880 | ||
Lineage tracing evidence for transdifferentiation of acinar to duct cells and plasticity of human pancreas. | Q50517982 | ||
Single-Cell Analysis Uncovers Clonal Acinar Cell Heterogeneity in the Adult Pancreas. | Q50539043 | ||
Acinar Ductal Metaplasia: Yap Fills a Gap. | Q50859291 | ||
Lgr5 joins the club of gastric stem cell markers in the corpus. | Q50917892 | ||
Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. | Q51056982 | ||
Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis. | Q51061806 | ||
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. | Q51894736 | ||
SOX9 regulates ERBB signalling in pancreatic cancer development. | Q53229089 | ||
Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice | Q53379866 | ||
Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis. | Q54394742 | ||
Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice | Q61776577 | ||
Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast | Q67660860 | ||
Development of adenocarcinomas in the stomach | Q68954575 | ||
Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells | Q72848879 | ||
Duct changes and K-ras mutations in the disease-free pancreas: analysis of type, age relation and spatial distribution | Q73258134 | ||
The developmental capacity of nuclei taken from differentiating endoderm cells of Xenopus laevis | Q78862450 | ||
Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice | Q81264382 | ||
Re-evaluation of histogenesis of gastric carcinomas: a comparative histopathological study between Helicobacter pylori-negative and H. pylori-positive cases | Q81795383 | ||
Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma | Q82193149 | ||
Heart of newt: a recipe for regeneration | Q84434706 | ||
Oncofetal signaling as a target for cancer therapy | Q87543989 | ||
Experimental models of pancreatitis | Q88110599 | ||
Paligenosis: prepare to regenerate! | Q88137469 | ||
A single transcription factor is sufficient to induce and maintain secretory cell architecture | Q37661675 | ||
Refining the role for adult stem cells as cancer cells of origin | Q38252977 | ||
Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion. | Q38710117 | ||
KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis | Q38786245 | ||
Cellular plasticity: 1712 to the present day. | Q38916687 | ||
Acinar cell plasticity and development of pancreatic ductal adenocarcinoma | Q38922230 | ||
Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation | Q39156056 | ||
NF-κB Signaling in Gastric Cancer. | Q39204794 | ||
Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia. | Q39337159 | ||
A human model of gastric carcinogenesis. | Q39644851 | ||
Retrodifferentiation and the Fetal Patterns of Gene Expression in Cancer | Q39805011 | ||
The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation | Q39958892 | ||
Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells. | Q39979747 | ||
Distinct prognostic values of YAP1 in gastric cancer | Q40256327 | ||
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice | Q40679145 | ||
Multipotential stem cells in adult mouse gastric epithelium | Q40710512 | ||
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions | Q34517052 | ||
Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α | Q34590266 | ||
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice | Q34616196 | ||
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma | Q34642090 | ||
Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions | Q34943207 | ||
Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia | Q35376826 | ||
Risk of pancreatic adenocarcinoma in chronic pancreatitis | Q35595218 | ||
The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential. | Q35732360 | ||
Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia | Q35928158 | ||
Identification and analysis of precursors to invasive pancreatic cancer. | Q35948700 | ||
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma | Q35954277 | ||
Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation. | Q35994058 | ||
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche. | Q36386294 | ||
SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine. | Q36452176 | ||
In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia | Q36478584 | ||
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration | Q36570146 | ||
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice | Q36677747 | ||
Acute pancreatitis: animal models and recent advances in basic research | Q36696668 | ||
Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions | Q36730863 | ||
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation | Q36733456 | ||
Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells | Q36765691 | ||
Dynamics of epithelial cells in the corpus of the mouse stomach. V. Behavior of entero-endocrine and caveolated cells: general conclusions on cell kinetics in the oxyntic epithelium | Q36765694 | ||
Hippo signaling regulates differentiation and maintenance in the exocrine pancreas | Q36881032 | ||
The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation | Q36890737 | ||
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia | Q36980230 | ||
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice | Q36999854 | ||
Tamoxifen induces rapid, reversible atrophy, and metaplasia in mouse stomach | Q37003243 | ||
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs. | Q37071752 | ||
Stomach Organ and Cell Lineage Differentiation: from Embryogenesis to Adult Homeostasis. | Q37259840 | ||
MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice. | Q37413667 | ||
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia | Q37501557 | ||
Modeling Murine Gastric Metaplasia Through Tamoxifen-Induced Acute Parietal Cell Loss. | Q37572782 | ||
Murine Models of Gastric Corpus Preneoplasia. | Q37594950 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 7 | |
P921 | main subject | stomach | Q1029907 |
cell differentiation | Q210861 | ||
wound healing | Q1509074 | ||
carcinogenesis | Q1637543 | ||
P577 | publication date | 2018-07-23 | |
P1433 | published in | Disease Models & Mechanisms | Q1524006 |
P1476 | title | Plasticity of differentiated cells in wound repair and tumorigenesis, part I: stomach and pancreas | |
P478 | volume | 11 |
Q90237358 | Interferon-γ directly induces gastric epithelial cell death and is required for progression to metaplasia |
Q58778696 | Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine |
Q90564951 | Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia |
Q98291542 | Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection |
Q57167592 | The big picture: exploring the metabolic cross-talk in cancer |
Search more.