| scholarly article | Q13442814 |
| P50 | author | Diva D De León | Q79716162 |
| P2093 | author name string | Doris A Stoffers | |
| Steven D Leach | |||
| Nankang Hong | |||
| Biva M Desai | |||
| Jennifer Oliver-Krasinski | |||
| Cyrus Farzad | |||
| P2860 | cites work | Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy | Q44286369 |
| Exocrine cell transdifferentiation in dexamethasone-treated rat pancreas | Q44675508 | ||
| Metabolic adaptations to chronic glucose infusion in rats | Q45045299 | ||
| No stem cell is an islet (yet). | Q46287689 | ||
| Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration | Q46376132 | ||
| Very slow turnover of beta-cells in aged adult mice | Q46670100 | ||
| Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene | Q69344366 | ||
| p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas | Q73004031 | ||
| Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans | Q73033722 | ||
| Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells | Q73224788 | ||
| Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter | Q73473642 | ||
| Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice | Q73803430 | ||
| Lectin as a marker for staining and purification of embryonic pancreatic epithelium | Q74259249 | ||
| Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates | Q80378426 | ||
| Pancreatic islet transplantation | Q24809607 | ||
| Generalized lacZ expression with the ROSA26 Cre reporter strain | Q27860837 | ||
| Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats | Q28578709 | ||
| Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro | Q28578821 | ||
| Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation | Q29614736 | ||
| Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors | Q29619012 | ||
| Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells. | Q33841070 | ||
| Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells | Q34085147 | ||
| Five stages of evolving beta-cell dysfunction during progression to diabetes | Q35961960 | ||
| Advances in pancreatic islet transplantation in humans | Q36347873 | ||
| The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice | Q36919881 | ||
| Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases | Q39729499 | ||
| Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells | Q39762883 | ||
| Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. | Q40051311 | ||
| Molecular basis of transdifferentiation of pancreas to liver | Q40833571 | ||
| Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor | Q41172703 | ||
| Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation | Q42091306 | ||
| Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas | Q43651806 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 971-977 | |
| P577 | publication date | 2007-04-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration | |
| P478 | volume | 117 |
| Q46488637 | A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia. |
| Q35364728 | A computer-based automated algorithm for assessing acinar cell loss after experimental pancreatitis |
| Q30441221 | A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis |
| Q33882658 | Aberrant innate immune activation following tissue injury impairs pancreatic regeneration |
| Q38459854 | Acinar cell reprogramming: a clinically important target in pancreatic disease |
| Q34131104 | Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis |
| Q42282476 | Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells |
| Q46185294 | Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice |
| Q27312357 | Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage |
| Q34082522 | Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras |
| Q37193696 | Adaptive beta-cell proliferation is severely restricted with advanced age. |
| Q33929630 | Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling |
| Q30356946 | Adult tissue sources for new β cells. |
| Q26766670 | Alcoholic pancreatitis: New insights into the pathogenesis and treatment |
| Q37039738 | Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges |
| Q35801749 | Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin |
| Q37363537 | Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells |
| Q33604913 | Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice |
| Q35757180 | Beta-cell growth and regeneration: replication is only part of the story |
| Q36359854 | Bmi1 is required for regeneration of the exocrine pancreas in mice |
| Q37182612 | Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis |
| Q37864191 | Body mass index and outcomes from pancreatic resection: a review and meta-analysis |
| Q37018928 | Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth |
| Q33525054 | Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass |
| Q37146186 | Cellular origins of beta-cell regeneration: a legacy view of historical controversies |
| Q37709553 | Cellular plasticity within the pancreas--lessons learned from development |
| Q52366287 | Comparative regenerative mechanisms across different mammalian tissues. |
| Q38434660 | Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation. |
| Q27013646 | Concise review: pancreas regeneration: recent advances and perspectives |
| Q34735035 | Concise reviews: In vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors. |
| Q51894736 | Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. |
| Q51734170 | DIE-RNA: A Reproducible Strategy for the Digestion of Normal and Injured Pancreas, Isolation of Pancreatic Cells from Genetically Engineered Mouse Models and Extraction of High Quality RNA. |
| Q36009271 | Deconstructing pancreas developmental biology |
| Q42720344 | Development and regeneration in the endocrine pancreas |
| Q33705205 | Development of factors to convert frequency to rate for beta-cell replication and apoptosis quantified by time-lapse video microscopy and immunohistochemistry |
| Q37156679 | Diabetes mellitus: an opportunity for therapy with stem cells? |
| Q35432049 | Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia |
| Q91595228 | Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma |
| Q43144435 | Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice |
| Q47111525 | Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression. |
| Q34030984 | EZH2 couples pancreatic regeneration to neoplastic progression |
| Q35444326 | Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas |
| Q47557792 | Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes. |
| Q28581365 | Enhanced beta-cell mass without increased proliferation following chronic mild glucose infusion |
| Q36341991 | Ethanol administration impairs pancreatic repair after injury |
| Q33551040 | Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas. |
| Q38625919 | Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice |
| Q35774014 | FTY720 normalizes hyperglycemia by stimulating β-cell in vivo regeneration in db/db mice through regulation of cyclin D3 and p57(KIP2). |
| Q57767553 | From tissue turnover to the cell of origin for pancreatic cancer |
| Q34099383 | GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches |
| Q37776424 | Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas |
| Q41761890 | Hedgehog signaling is required for effective regeneration of exocrine pancreas |
| Q91297699 | Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis |
| Q43104032 | Heterogeneity in mitotic activity and telomere length implies an important role of young islets in the maintenance of islet mass in the adult pancreas |
| Q93162259 | Human duct cells contribute to β cell compensation in insulin resistance |
| Q41856856 | Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma |
| Q36478584 | In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia |
| Q46383363 | Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes |
| Q36217705 | Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy |
| Q34001106 | Isolation, culture and genetic manipulation of mouse pancreatic ductal cells |
| Q33858490 | KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. |
| Q41602913 | Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas. |
| Q93013774 | Lower Nr5a2 Level Downregulates the β-Catenin and TCF-4 Expression in Caerulein-Induced Pancreatic Inflammation |
| Q37687626 | M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7. |
| Q98187297 | Macrophage phenotypic switch orchestrates the inflammation and repair/regeneration following acute pancreatitis injury |
| Q38127356 | Making β cells from adult cells within the pancreas |
| Q51975119 | MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. |
| Q37585776 | Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis |
| Q38934951 | Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas |
| Q26771156 | Multipotent pancreas progenitors: Inconclusive but pivotal topic |
| Q34490166 | Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate |
| Q37278665 | Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas |
| Q37132108 | Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas. |
| Q36905220 | New sources of pancreatic beta cells |
| Q36805115 | No evidence for β cell neogenesis in murine adult pancreas |
| Q34533078 | Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma |
| Q38329689 | Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. |
| Q37997980 | Organ repair and regeneration: an overview. |
| Q37845287 | Pancreas organogenesis: from bud to plexus to gland |
| Q59092532 | Pancreas regeneration |
| Q27011305 | Pancreas-specific Cre driver lines and considerations for their prudent use |
| Q90013271 | Pancreatic Progenitors: There and Back Again |
| Q37765396 | Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment |
| Q34258845 | Pancreatic beta-cells: from generation to regeneration |
| Q37331079 | Pancreatic duct ligation after almost complete β-cell loss: exocrine regeneration but no evidence of β-cell regeneration |
| Q26853634 | Pancreatic stem cells remain unresolved |
| Q37957024 | Pancreatic stem cells: from possible to probable |
| Q42437521 | Pancreatic tissue resident mesenchymal stromal cell (MSC)-like cells as a source of in vitro islet neogenesis |
| Q99631198 | Pancreatic β cell regeneration: To β or not to β |
| Q36803303 | Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells |
| Q37589374 | Pathogenesis of pancreatic cancer: lessons from animal models |
| Q41737306 | Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease |
| Q38186823 | Postembryonic organogenesis of the digestive tube: why does it occur in worms and sea cucumbers but fail in humans? |
| Q35158996 | Progenitor cell domains in the developing and adult pancreas |
| Q90564951 | Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia |
| Q42876614 | Putting pancreatic cell plasticity to the test. |
| Q34055977 | Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction |
| Q33709750 | Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis |
| Q35071666 | Regeneration and repair of the exocrine pancreas |
| Q37768701 | Regenerative medicine for insulin deficiency: creation of pancreatic islets and bioartificial pancreas |
| Q26863661 | Reprogramming pancreatic cells to β cells |
| Q40060870 | Robust acinar cell transgene expression of CreErT via BAC recombineering |
| Q27023929 | Role of Parathyroid Hormone-Related Protein Signaling in Chronic Pancreatitis |
| Q46708937 | Role of cadherin-mediated cell-cell adhesion in pancreatic exocrine-to-endocrine transdifferentiation |
| Q37501557 | Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia |
| Q53229089 | SOX9 regulates ERBB signalling in pancreatic cancer development. |
| Q36212308 | Salivary Glands: Stem Cells, Self-duplication, or Both? |
| Q92432198 | Salivary glands require Aurora Kinase B for regeneration after transient innate immune-mediated injury |
| Q33647542 | Slow and steady is the key to beta-cell replication |
| Q38103364 | Sox9 and programming of liver and pancreatic progenitors |
| Q34972366 | Sox9: a master regulator of the pancreatic program |
| Q36570146 | Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration |
| Q37369660 | Stem Cells in the Treatment of Insulin-Dependent Diabetes Mellitus |
| Q38748909 | Stem cells versus plasticity in liver and pancreas regeneration. |
| Q33874704 | Suppression of Ptf1a activity induces acinar-to-endocrine conversion. |
| Q58697165 | Suppression of STAT3 signaling promotes cellular reprogramming into insulin-producing cells induced by defined transcription factors |
| Q52354472 | TUMOR CROSSTALK NETWORKS PROMOTE GROWTH AND SUPPORT IMMUNE EVASION IN PANCREATIC CANCER. |
| Q34217394 | Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice |
| Q41463557 | Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer. |
| Q38622477 | The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regeneration. |
| Q37808123 | The quest for tissue stem cells in the pancreas and other organs, and their application in beta-cell replacement |
| Q38123370 | The use of stem cells for pancreatic regeneration in diabetes mellitus |
| Q35077784 | The versatile functions of Sox9 in development, stem cells, and human diseases |
| Q38822489 | Three-dimensional pancreas organogenesis models. |
| Q39026534 | Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue |
| Q91284108 | Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis |
| Q34627354 | Tracking adult stem cells. |
| Q28083955 | Transcription factor regulation of pancreatic organogenesis, differentiation and maturation |
| Q36104264 | Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice |
| Q33897644 | Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice |
| Q89964422 | Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis |
| Q28083091 | Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models |
| Q53109923 | [Cellular therapy of diabetes: focus on the latest developments]. |
| Q37651619 | miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal. |
| Q39048945 | p53 status determines the role of autophagy in pancreatic tumour development |
| Q43006061 | p53: Guardian of pancreatic epithelial identity |
| Q42293235 | ptf1a+ , ela3l- cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae |
| Q35294804 | β-Cell Generation: Can Rodent Studies Be Translated to Humans? |
| Q38134109 | β-Cell differentiation and regeneration in type 1 diabetes |
| Q26743633 | β-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas |
| Q36051065 | β-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice |
| Q26740314 | β-cell replacement sources for type 1 diabetes: a focus on pancreatic ductal cells |
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