scholarly article | Q13442814 |
P50 | author | Diva D De León | Q79716162 |
P2093 | author name string | Doris A Stoffers | |
Steven D Leach | |||
Nankang Hong | |||
Biva M Desai | |||
Jennifer Oliver-Krasinski | |||
Cyrus Farzad | |||
P2860 | cites work | Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy | Q44286369 |
Exocrine cell transdifferentiation in dexamethasone-treated rat pancreas | Q44675508 | ||
Metabolic adaptations to chronic glucose infusion in rats | Q45045299 | ||
No stem cell is an islet (yet). | Q46287689 | ||
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration | Q46376132 | ||
Very slow turnover of beta-cells in aged adult mice | Q46670100 | ||
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene | Q69344366 | ||
p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas | Q73004031 | ||
Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans | Q73033722 | ||
Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells | Q73224788 | ||
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter | Q73473642 | ||
Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice | Q73803430 | ||
Lectin as a marker for staining and purification of embryonic pancreatic epithelium | Q74259249 | ||
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates | Q80378426 | ||
Pancreatic islet transplantation | Q24809607 | ||
Generalized lacZ expression with the ROSA26 Cre reporter strain | Q27860837 | ||
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats | Q28578709 | ||
Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro | Q28578821 | ||
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation | Q29614736 | ||
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors | Q29619012 | ||
Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells. | Q33841070 | ||
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells | Q34085147 | ||
Five stages of evolving beta-cell dysfunction during progression to diabetes | Q35961960 | ||
Advances in pancreatic islet transplantation in humans | Q36347873 | ||
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice | Q36919881 | ||
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases | Q39729499 | ||
Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells | Q39762883 | ||
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. | Q40051311 | ||
Molecular basis of transdifferentiation of pancreas to liver | Q40833571 | ||
Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor | Q41172703 | ||
Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation | Q42091306 | ||
Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas | Q43651806 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 971-977 | |
P577 | publication date | 2007-04-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration | |
P478 | volume | 117 |
Q46488637 | A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia. |
Q35364728 | A computer-based automated algorithm for assessing acinar cell loss after experimental pancreatitis |
Q30441221 | A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis |
Q33882658 | Aberrant innate immune activation following tissue injury impairs pancreatic regeneration |
Q38459854 | Acinar cell reprogramming: a clinically important target in pancreatic disease |
Q34131104 | Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis |
Q42282476 | Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells |
Q46185294 | Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice |
Q27312357 | Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage |
Q34082522 | Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras |
Q37193696 | Adaptive beta-cell proliferation is severely restricted with advanced age. |
Q33929630 | Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling |
Q30356946 | Adult tissue sources for new β cells. |
Q26766670 | Alcoholic pancreatitis: New insights into the pathogenesis and treatment |
Q37039738 | Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges |
Q35801749 | Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin |
Q37363537 | Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells |
Q33604913 | Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice |
Q35757180 | Beta-cell growth and regeneration: replication is only part of the story |
Q36359854 | Bmi1 is required for regeneration of the exocrine pancreas in mice |
Q37182612 | Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis |
Q37864191 | Body mass index and outcomes from pancreatic resection: a review and meta-analysis |
Q37018928 | Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth |
Q33525054 | Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass |
Q37146186 | Cellular origins of beta-cell regeneration: a legacy view of historical controversies |
Q37709553 | Cellular plasticity within the pancreas--lessons learned from development |
Q52366287 | Comparative regenerative mechanisms across different mammalian tissues. |
Q38434660 | Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation. |
Q27013646 | Concise review: pancreas regeneration: recent advances and perspectives |
Q34735035 | Concise reviews: In vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors. |
Q51894736 | Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. |
Q51734170 | DIE-RNA: A Reproducible Strategy for the Digestion of Normal and Injured Pancreas, Isolation of Pancreatic Cells from Genetically Engineered Mouse Models and Extraction of High Quality RNA. |
Q36009271 | Deconstructing pancreas developmental biology |
Q42720344 | Development and regeneration in the endocrine pancreas |
Q33705205 | Development of factors to convert frequency to rate for beta-cell replication and apoptosis quantified by time-lapse video microscopy and immunohistochemistry |
Q37156679 | Diabetes mellitus: an opportunity for therapy with stem cells? |
Q35432049 | Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia |
Q91595228 | Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma |
Q43144435 | Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice |
Q47111525 | Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression. |
Q34030984 | EZH2 couples pancreatic regeneration to neoplastic progression |
Q35444326 | Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas |
Q47557792 | Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes. |
Q28581365 | Enhanced beta-cell mass without increased proliferation following chronic mild glucose infusion |
Q36341991 | Ethanol administration impairs pancreatic repair after injury |
Q33551040 | Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas. |
Q38625919 | Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice |
Q35774014 | FTY720 normalizes hyperglycemia by stimulating β-cell in vivo regeneration in db/db mice through regulation of cyclin D3 and p57(KIP2). |
Q57767553 | From tissue turnover to the cell of origin for pancreatic cancer |
Q34099383 | GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches |
Q37776424 | Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas |
Q41761890 | Hedgehog signaling is required for effective regeneration of exocrine pancreas |
Q91297699 | Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis |
Q43104032 | Heterogeneity in mitotic activity and telomere length implies an important role of young islets in the maintenance of islet mass in the adult pancreas |
Q93162259 | Human duct cells contribute to β cell compensation in insulin resistance |
Q41856856 | Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma |
Q36478584 | In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia |
Q46383363 | Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes |
Q36217705 | Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy |
Q34001106 | Isolation, culture and genetic manipulation of mouse pancreatic ductal cells |
Q33858490 | KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. |
Q41602913 | Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas. |
Q93013774 | Lower Nr5a2 Level Downregulates the β-Catenin and TCF-4 Expression in Caerulein-Induced Pancreatic Inflammation |
Q37687626 | M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7. |
Q98187297 | Macrophage phenotypic switch orchestrates the inflammation and repair/regeneration following acute pancreatitis injury |
Q38127356 | Making β cells from adult cells within the pancreas |
Q51975119 | MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. |
Q37585776 | Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis |
Q38934951 | Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas |
Q26771156 | Multipotent pancreas progenitors: Inconclusive but pivotal topic |
Q34490166 | Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate |
Q37278665 | Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas |
Q37132108 | Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas. |
Q36905220 | New sources of pancreatic beta cells |
Q36805115 | No evidence for β cell neogenesis in murine adult pancreas |
Q34533078 | Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma |
Q38329689 | Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. |
Q37997980 | Organ repair and regeneration: an overview. |
Q37845287 | Pancreas organogenesis: from bud to plexus to gland |
Q59092532 | Pancreas regeneration |
Q27011305 | Pancreas-specific Cre driver lines and considerations for their prudent use |
Q90013271 | Pancreatic Progenitors: There and Back Again |
Q37765396 | Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment |
Q34258845 | Pancreatic beta-cells: from generation to regeneration |
Q37331079 | Pancreatic duct ligation after almost complete β-cell loss: exocrine regeneration but no evidence of β-cell regeneration |
Q26853634 | Pancreatic stem cells remain unresolved |
Q37957024 | Pancreatic stem cells: from possible to probable |
Q42437521 | Pancreatic tissue resident mesenchymal stromal cell (MSC)-like cells as a source of in vitro islet neogenesis |
Q99631198 | Pancreatic β cell regeneration: To β or not to β |
Q36803303 | Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells |
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Q42876614 | Putting pancreatic cell plasticity to the test. |
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Q37369660 | Stem Cells in the Treatment of Insulin-Dependent Diabetes Mellitus |
Q38748909 | Stem cells versus plasticity in liver and pancreas regeneration. |
Q33874704 | Suppression of Ptf1a activity induces acinar-to-endocrine conversion. |
Q58697165 | Suppression of STAT3 signaling promotes cellular reprogramming into insulin-producing cells induced by defined transcription factors |
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Q34217394 | Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice |
Q41463557 | Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer. |
Q38622477 | The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regeneration. |
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Q38822489 | Three-dimensional pancreas organogenesis models. |
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Q34627354 | Tracking adult stem cells. |
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