scholarly article | Q13442814 |
P50 | author | Guido von Figura | Q63133710 |
P2093 | author name string | Haruhiko Akiyama | |
Christopher V E Wright | |||
Kristin Jensen | |||
Maike Sander | |||
John P Morris | |||
Matthias Hebrok | |||
Claire L Dubois | |||
Janel L Kopp | |||
Fong Cheng Pan | |||
Erin Mayes | |||
Fen-Fen Liu | |||
P2860 | cites work | Identification of a cell of origin for human prostate cancer | Q24594400 |
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EGF receptor is required for KRAS-induced pancreatic tumorigenesis | Q28584901 | ||
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas | Q28584996 | ||
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice | Q29617045 | ||
Cells of origin in cancer | Q29619557 | ||
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse | Q29620396 | ||
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas | Q33591500 | ||
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice | Q33604913 | ||
Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia | Q33754775 | ||
Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice | Q61776577 | ||
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis | Q73614651 | ||
Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model | Q33818230 | ||
Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras | Q34082522 | ||
Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer | Q34241383 | ||
Genetics and biology of pancreatic ductal adenocarcinoma. | Q34567515 | ||
Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras | Q34620985 | ||
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma | Q34642090 | ||
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. | Q35097448 | ||
Hedgehog/Ras interactions regulate early stages of pancreatic cancer | Q35127709 | ||
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia | Q35663506 | ||
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. | Q35921887 | ||
Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia | Q35928158 | ||
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation | Q36058628 | ||
In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia | Q36478584 | ||
EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma | Q36696146 | ||
Molecular genetics of pancreatic intraepithelial neoplasia | Q36829524 | ||
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia | Q36980230 | ||
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Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia | Q37249748 | ||
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia | Q37501557 | ||
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network | Q38626764 | ||
Pancreatic Intraepithelial Neoplasia | Q38720267 | ||
Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia. | Q39337159 | ||
Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation | Q39484183 | ||
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma | Q39885220 | ||
SOX9cre1, a cis-acting regulatory element located 1.1 Mb upstream of SOX9, mediates its enhancement through the SHH pathway | Q40149526 | ||
Hedgehog signaling is required for effective regeneration of exocrine pancreas | Q41761890 | ||
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration | Q41791253 | ||
Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia | Q41816001 | ||
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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. | Q41979160 | ||
Notch signaling controls liver development by regulating biliary differentiation | Q42080795 | ||
Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors | Q42473171 | ||
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. | Q42876632 | ||
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth | Q43199149 | ||
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration | Q46376132 | ||
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas | Q46708964 | ||
The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade | Q47867912 | ||
Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. | Q51056982 | ||
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. | Q52172849 | ||
Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN. | Q53329413 | ||
The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice. | Q53379869 | ||
P433 | issue | 6 | |
P921 | main subject | adenocarcinoma | Q356033 |
P304 | page(s) | 737-750 | |
P577 | publication date | 2012-11-29 | |
P1433 | published in | Cancer Cell | Q280018 |
P1476 | title | Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma | |
P478 | volume | 22 |
Q92905126 | A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma |
Q28082890 | A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas |
Q90950168 | A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells |
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Q91711463 | ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis |
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Q38922230 | Acinar cell plasticity and development of pancreatic ductal adenocarcinoma |
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Q42282476 | Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells |
Q41105264 | Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis. |
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Q64098116 | Antibodies to a CA 19-9 Related Antigen Complex Identify SOX9 Expressing Progenitor Cells In Human Foetal Pancreas and Pancreatic Adenocarcinoma |
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Q46862467 | Atypical flat lesions derive from pancreatic acinar cells |
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Q39161835 | Cells of origin of pancreatic neoplasms |
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Q93147190 | Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice |
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Q35161464 | Dicer regulates differentiation and viability during mouse pancreatic cancer initiation |
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