scholarly article | Q13442814 |
P50 | author | Mariusz L Hartman | Q59660628 |
Malgorzata Sztiller-Sikorska | Q91587525 | ||
Malgorzata Czyz | Q37836897 | ||
P2093 | author name string | Anna Gajos-Michniewicz | |
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Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E. | Q46132721 | ||
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HGF/c-MET Signaling in Melanocytes and Melanoma | Q60920855 | ||
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IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor | Q72901004 | ||
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ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma | Q90706191 | ||
RBMX family proteins connect the fields of nuclear RNA processing, disease and sex chromosome biology | Q90800009 | ||
Bad company: Microenvironmentally mediated resistance to targeted therapy in melanoma | Q91450739 | ||
Many ways to resistance: How melanoma cells evade targeted therapies | Q91678258 | ||
Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway | Q91725276 | ||
S100-EPISPOT: A New Tool to Detect Viable Circulating Melanoma Cells | Q92081486 | ||
The current state of molecular testing in the treatment of patients with solid tumors, 2019 | Q92214210 | ||
Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program | Q92240577 | ||
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Fibroblast Growth Factor Receptor Signaling in Skin Cancers | Q92544513 | ||
Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma | Q92642778 | ||
Phenotype plasticity as enabler of melanoma progression and therapy resistance | Q92826006 | ||
Physiologically Relevant Oxygen Concentration (6% O2) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro | Q92960597 | ||
17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes | Q93118409 | ||
Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance | Q36489360 | ||
Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma | Q36507554 | ||
Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells | Q36605057 | ||
Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy | Q36698266 | ||
Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib | Q36882715 | ||
Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor | Q36929804 | ||
Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas | Q37118264 | ||
Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma | Q37239090 | ||
TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma | Q37401151 | ||
Epidermal growth factor regulates the expression of its own receptor | Q37538959 | ||
Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2. | Q37570262 | ||
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy | Q37606223 | ||
The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma | Q37626102 | ||
MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition | Q37626175 | ||
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma | Q37641646 | ||
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma | Q37660341 | ||
Precision medicine driven by cancer systems biology | Q37742635 | ||
Tumor heterogeneity and plasticity as elusive drivers for resistance to MAPK pathway inhibition in melanoma | Q38238524 | ||
Pro-survival role of MITF in melanoma | Q38241749 | ||
The discovery of vemurafenib for the treatment of BRAF-mutated metastatic melanoma | Q38559739 | ||
A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib | Q38757495 | ||
Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma. | Q38849622 | ||
Expression and activity of EGFR in human cutaneous melanoma cell lines and influence of vemurafenib on the EGFR pathway | Q38995370 | ||
BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact. | Q39030603 | ||
MAPK pathway in melanoma part II-secondary and adaptive resistance mechanisms to BRAF inhibition. | Q39120374 | ||
Acquired resistance to BRAF inhibition can confer cross-resistance to combined BRAF/MEK inhibition. | Q39375855 | ||
SOX2 contributes to melanoma cell invasion | Q39425345 | ||
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation | Q39583072 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phenotypic plasticity | Q295130 |
P304 | page(s) | 142 | |
P577 | publication date | 2020-01-07 | |
P1433 | published in | Cells | Q27724621 |
P1476 | title | Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity | |
P478 | volume | 9 |
Q97074415 | Histone Deacetylase Inhibitors to Overcome Resistance to Targeted and Immuno Therapy in Metastatic Melanoma | cites work | P2860 |