| P2093 | author name string | Jason C Mills | |
| | Ramon U Jin | |
| P2860 | cites work | CDX1 is an important molecular mediator of Barrett's metaplasia | Q24529062 |
| | The origin of pre-neoplastic metaplasia in the stomach: chief cells emerge from the Mist | Q24630749 |
| | Mature chief cells are cryptic progenitors for metaplasia in the stomach | Q24631089 |
| | Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract | Q26801731 |
| | Global cancer statistics, 2012 | Q27860501 |
| | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors | Q27860937 |
| | Induction of pluripotent stem cells from adult human fibroblasts by defined factors | Q27860967 |
| | Generation of germline-competent induced pluripotent stem cells | Q28131699 |
| | Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer | Q28389284 |
| | Cdx2 determines the fate of postnatal intestinal endoderm | Q28504729 |
| | Six2 activity is required for the formation of the mammalian pyloric sphincter | Q28506654 |
| | Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine | Q28510344 |
| | Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis | Q28510349 |
| | Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm | Q28510560 |
| | Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen | Q28511280 |
| | Activin receptor patterning of foregut organogenesis | Q28511454 |
| | Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives | Q28511721 |
| | Hedgehog signals regulate multiple aspects of gastrointestinal development | Q28511934 |
| | GATA-4:FOG interactions regulate gastric epithelial development in the mouse | Q28513592 |
| | Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development | Q28586203 |
| | GATA4 transcription factor is required for ventral morphogenesis and heart tube formation | Q28586495 |
| | p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development | Q28587664 |
| | Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps | Q28588087 |
| | Sonic hedgehog is essential to foregut development | Q28591429 |
| | Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis | Q28592331 |
| | Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling | Q28592418 |
| | Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium | Q28593684 |
| | Generation of mouse induced pluripotent stem cells without viral vectors | Q29614342 |
| | PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum | Q29618151 |
| | Murine Models of Gastric Corpus Preneoplasia. | Q37594950 |
| | Current understanding of SPEM and its standing in the preneoplastic process | Q37666872 |
| | Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma. | Q37687546 |
| | Oxyntic atrophy, metaplasia, and gastric cancer | Q37809358 |
| | Cdx genes, inflammation, and the pathogenesis of intestinal metaplasia | Q37809363 |
| | The molecular biology of head and neck cancer | Q37821229 |
| | Hedgehog signalling in gut development, physiology and cancer | Q37965128 |
| | Embryological signaling pathways in Barrett's metaplasia development and malignant transformation; mechanisms and therapeutic opportunities. | Q38220736 |
| | On the histogenesis of Barrett's oesophagus and its associated squamous islands: a three-dimensional study of their morphological relationship with native oesophageal gland ducts | Q38442567 |
| | Barrett's esophagus is characterized by expression of gastric-type mucins (MUC5AC, MUC6) and TFF peptides (TFF1 and TFF2), but the risk of carcinoma development may be indicated by the intestinal-type mucin, MUC2. | Q38455761 |
| | Esophageal development and epithelial homeostasis | Q38542183 |
| | Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair | Q38676008 |
| | Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux | Q38710911 |
| | Late Recurrence of Barrett's Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial | Q38745392 |
| | Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium | Q38762525 |
| | Hedgehog signaling in the stomach | Q38983010 |
| | A pSMAD/CDX2 complex is essential for the intestinalization of epithelial metaplasia. | Q38998773 |
| | Integrated genomic characterization of oesophageal carcinoma | Q39041152 |
| | Mechanisms of embryonic stomach development | Q39151720 |
| | Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium. | Q39163004 |
| | Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions | Q39169684 |
| | The Evolving Genomic Landscape of Barrett's Esophagus and Esophageal Adenocarcinoma | Q39440077 |
| | Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus. | Q39536731 |
| | NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network | Q39662272 |
| | Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia | Q39742785 |
| | Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture | Q40110595 |
| | SOX2 as a novel marker to predict neoplastic progression in Barrett's esophagus. | Q40590481 |
| | Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. | Q40671403 |
| | Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice | Q40679145 |
| | Cdx1 and cdx2 expression during intestinal development | Q40847809 |
| | Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals | Q40926487 |
| | Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells | Q41260832 |
| | BMP signaling in the development of the mouse esophagus and forestomach | Q41591432 |
| | Modelling human development and disease in pluripotent stem-cell-derived gastric organoids | Q41680408 |
| | Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation | Q41705186 |
| | Expression of the p53 homologue p63alpha and DeltaNp63alpha in the neoplastic sequence of Barrett's oesophagus: correlation with morphology and p53 protein | Q41816694 |
| | Spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia: time for reevaluation of metaplasias and the origins of gastric cancer. | Q41861115 |
| | Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. | Q41867864 |
| | Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus | Q41919300 |
| | The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands | Q41995266 |
| | SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype | Q42093341 |
| | Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes | Q42438360 |
| | The role of p63 and ΔNp63 (p40) protein expression and gene amplification in esophageal carcinogenesis | Q42451467 |
| | Identification and genetic manipulation of human and mouse oesophageal stem cells | Q42475984 |
| | Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus. | Q42480726 |
| | Reversible drug-induced oxyntic atrophy in rats | Q42488660 |
| | Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus. | Q42504859 |
| | Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders | Q42513532 |
| | CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium | Q42798173 |
| | Cdx2 as a Marker of Epithelial Intestinal Differentiation in the Esophagus | Q30311906 |
| | Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation | Q31028060 |
| | Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers | Q33314440 |
| | A molecular signature of gastric metaplasia arising in response to acute parietal cell loss | Q33317849 |
| | Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus | Q33321476 |
| | Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus | Q33379614 |
| | Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice | Q33604913 |
| | Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma. | Q33667106 |
| | Metaplasia in the Stomach Arises From Gastric Chief Cells | Q33714766 |
| | Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus | Q33714773 |
| | Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia | Q33750475 |
| | GATA4 is essential for jejunal function in mice | Q33750585 |
| | Barrett's Stem Cells as a Unique and Targetable Entity | Q33753417 |
| | Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract | Q33812943 |
| | Lack of TCF2/vHNF1 in mice leads to pancreas agenesis | Q33817745 |
| | KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. | Q33858490 |
| | Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus | Q33873724 |
| | Wnt/β-catenin promotes gastric fundus specification in mice and humans | Q33926430 |
| | Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling | Q33929630 |
| | Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus | Q33987356 |
| | Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments | Q34062778 |
| | Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras | Q34082522 |
| | The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma. | Q34087033 |
| | Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice | Q34222321 |
| | Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression | Q34330645 |
| | The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut | Q34358918 |
| | Bone Morphogenetic Protein Signaling Regulates Gastric Epithelial Cell Development and Proliferation in Mice | Q34576465 |
| | How cells change their phenotype | Q34627229 |
| | Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells. | Q34637751 |
| | Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. | Q34977220 |
| | Residual embryonic cells as precursors of a Barrett's-like metaplasia. | Q35073657 |
| | Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue | Q35235374 |
| | Mucin gene expression in Barrett's oesophagus: an in situ hybridisation and immunohistochemical study | Q35362159 |
| | BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis | Q35408666 |
| | Characterization of the cell of origin for small cell lung cancer | Q35559970 |
| | Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention | Q35570715 |
| | Wnt signaling specifies and patterns intestinal endoderm. | Q35570994 |
| | Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst | Q35650857 |
| | Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma | Q35882329 |
| | The role of Cdx genes in the mammalian gut. | Q35884370 |
| | Improvement over time in outcomes for patients undergoing endoscopic therapy for Barrett's oesophagus-related neoplasia: 6-year experience from the first 500 patients treated in the UK patient registry | Q35891829 |
| | The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma | Q35954277 |
| | Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma | Q36117607 |
| | Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. | Q36188486 |
| | SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes | Q36322037 |
| | Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis | Q36378496 |
| | Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche. | Q36386294 |
| | SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine. | Q36452176 |
| | Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa | Q36570857 |
| | Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon | Q36635519 |
| | Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions | Q36730863 |
| | The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation | Q36733456 |
| | Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells | Q36765691 |
| | Dynamics of epithelial cells in the corpus of the mouse stomach. V. Behavior of entero-endocrine and caveolated cells: general conclusions on cell kinetics in the oxyntic epithelium | Q36765694 |
| | Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus | Q36968814 |
| | Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia | Q36980230 |
| | Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice | Q36999854 |
| | Tamoxifen induces rapid, reversible atrophy, and metaplasia in mouse stomach | Q37003243 |
| | Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles | Q37175469 |
| | Multiple roles for Sox2 in the developing and adult mouse trachea | Q37186879 |
| | The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival. | Q37227732 |
| | Stomach Organ and Cell Lineage Differentiation: from Embryogenesis to Adult Homeostasis. | Q37259840 |
| | Induction of intestinalization in human esophageal keratinocytes is a multistep process | Q37292684 |
| | Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium. | Q37451902 |
| | Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma. | Q37474733 |
| | Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia | Q37501557 |
| | Modeling Murine Gastric Metaplasia Through Tamoxifen-Induced Acute Parietal Cell Loss. | Q37572782 |
| | Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation | Q42800598 |
| | Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium | Q42844302 |
| | Epithelial metaplasia and the second anatomy | Q43590698 |
| | Expression of the intestinal marker Cdx2 in the columnar-lined esophagus with and without intestinal (Barrett's) metaplasia | Q47418093 |
| | Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell | Q47566401 |
| | Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence | Q47786705 |
| | Maturity and age influence chief cell ability to transdifferentiate into metaplasia | Q48028364 |
| | Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach. | Q48328395 |
| | Metaplastic Cells in the Stomach Arise, Independently of Stem Cells, via Dedifferentiation or Transdifferentiation of Chief Cells | Q49722529 |
| | Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer | Q49788912 |
| | Mature gastric chief cells are not required for the development of metaplasia. | Q49967633 |
| | Patterning the gastrointestinal epithelium to confer regional-specific functions | Q50021474 |
| | Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice. | Q50219168 |
| | Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis. | Q50422422 |
| | Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. | Q50501238 |
| | Lineage tracing evidence for transdifferentiation of acinar to duct cells and plasticity of human pancreas. | Q50517982 |
| | Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus. | Q51719344 |
| | Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium. | Q52125376 |
| | Dynamic histology of the antral epithelium in the mouse stomach: II. Ultrastructure and renewal of isthmal cells. | Q52268109 |
| | SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans. | Q53224289 |
| | SOX9 regulates ERBB signalling in pancreatic cancer development. | Q53229089 |
| | Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. | Q53241385 |
| | Cdx2 regulates patterning of the intestinal epithelium. | Q53350785 |
| | Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. | Q53384678 |
| | Defining epithelial cell progenitors in the human oxyntic mucosa. | Q53862513 |
| | Cell proliferation and differentiation in the squamous epithelium of the forestomach of the mouse | Q54198579 |
| | Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis. | Q54394742 |
| | Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. | Q55311810 |
| | Expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in Barrett's metaplasia and the native oesophageal epithelium: Delineation of epithelial phenotype | Q58105220 |
| | Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning | Q59600095 |
| | Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice | Q61776577 |
| | Dynamic histology of the antral epithelium in the mouse stomach: III. Ultrastructure and renewal of pit cells | Q70101514 |
| | Dynamic histology of the antral epithelium in the mouse stomach: IV. Ultrastructure and renewal of gland cells | Q70101518 |
| | Origin and migratory pathways of the eleven epithelial cell types present in the body of the mouse stomach | Q72047417 |
| | Mechanisms of columnar metaplasia and squamous regeneration in experimental Barrett's esophagus | Q72778552 |
| | Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells | Q72848879 |
| | Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss | Q72848882 |
| | Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice | Q74250578 |
| | Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling | Q74578245 |
| | Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori | Q79837317 |
| | Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells | Q80312119 |
| | Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice | Q81264382 |
| | Roles of caudal-related homeobox gene Cdx1 in oesophageal epithelial cells in Barrett's epithelium development | Q83172283 |
| | Barrett oesophagus: lessons on its origins from the lesion itself | Q85901179 |
| | Esophageal carcinoma | Q86401144 |
| | Barrett's esophagus | Q87672139 |
| P433 | issue | 8 | |
| P304 | page(s) | 2028-2041 | |
| P577 | publication date | 2018-08-01 | |
| P1433 | published in | Digestive Diseases and Sciences | Q15716711 |
| P1476 | title | Are Gastric and Esophageal Metaplasia Relatives? The Case for Barrett's Stemming from SPEM | |
| P478 | volume | 63 | |