| scholarly article | Q13442814 |
| P50 | author | Qi Ma | Q64451735 |
| Wen Liu | Q90875538 | ||
| P2093 | author name string | Jie Zhang | |
| Michael G Rosenfeld | |||
| Wenbo Li | |||
| Aneel Aggarwal | |||
| Kaki Wong | |||
| Kenny Ohgi | |||
| P2860 | cites work | The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK | Q21136168 |
| Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro | Q22008559 | ||
| Long noncoding RNA as modular scaffold of histone modification complexes | Q22065890 | ||
| Interaction of JMJD6 with single-stranded RNA | Q24294206 | ||
| ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs | Q24296905 | ||
| JMJD6 is a histone arginine demethylase | Q24298169 | ||
| Selective inhibition of BET bromodomains | Q24301009 | ||
| Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression | Q24301464 | ||
| Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals | Q24305149 | ||
| Characterization of the biochemical and biophysical properties of the phosphatidylserine receptor (PS-R) gene product | Q24307420 | ||
| Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing | Q24310337 | ||
| The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription | Q24316236 | ||
| TDRD3 is an effector molecule for arginine-methylated histone marks | Q24318709 | ||
| Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme | Q24321455 | ||
| PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression | Q24338563 | ||
| The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal | Q24556608 | ||
| Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities | Q24617969 | ||
| c-Myc regulates transcriptional pause release | Q24629119 | ||
| Mediator and cohesin connect gene expression and chromatin architecture | Q24632695 | ||
| RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo | Q24645367 | ||
| Suppression of inflammation by a synthetic histone mimic | Q27665789 | ||
| 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 | ||
| The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 | ||
| Histone modifications at human enhancers reflect global cell-type-specific gene expression | Q28238467 | ||
| BET bromodomain inhibition as a therapeutic strategy to target c-Myc | Q28247024 | ||
| Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4 | Q28267929 | ||
| Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters | Q28302903 | ||
| Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. | Q28508455 | ||
| Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor | Q28510377 | ||
| Phosphatidylserine receptor is required for clearance of apoptotic cells | Q28513214 | ||
| A receptor for phosphatidylserine-specific clearance of apoptotic cells | Q28586441 | ||
| Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells | Q29392187 | ||
| Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans | Q29394946 | ||
| Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase | Q29614789 | ||
| RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia | Q29617201 | ||
| Multivalent engagement of chromatin modifications by linked binding modules | Q29617236 | ||
| Selective inhibition of tumor oncogenes by disruption of super-enhancers | Q29617301 | ||
| Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression | Q30435010 | ||
| Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase. | Q31807459 | ||
| H4R3 methylation facilitates beta-globin transcription by regulating histone acetyltransferase binding and H3 acetylation | Q33722642 | ||
| Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA | Q34185076 | ||
| Noncoding transcription at enhancers: general principles and functional models | Q34294940 | ||
| Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation | Q34348069 | ||
| BET bromodomains mediate transcriptional pause release in heart failure | Q34361491 | ||
| Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription | Q35007045 | ||
| The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. | Q35096586 | ||
| An epigenetic road map for histone lysine methylation | Q35120983 | ||
| Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors | Q35661538 | ||
| Histone arginine methylation and its dynamic regulation | Q36250971 | ||
| The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase | Q36727254 | ||
| The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis | Q37339715 | ||
| Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. | Q37340291 | ||
| Control of inducible gene expression by signal-dependent transcriptional elongation | Q39285490 | ||
| B2 RNA and 7SK RNA, RNA polymerase III transcripts, have a cap-like structure at their 5′ end | Q40525547 | ||
| Chromatin isolation by RNA purification (ChIRP). | Q41846416 | ||
| Enhancer transcripts mark active estrogen receptor binding sites | Q42597586 | ||
| P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation | Q46904254 | ||
| The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting. | Q54450677 | ||
| Transcription: Enhancers make non-coding RNA. | Q55052904 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Bromodomain containing 4 | Q21100441 |
| Jumonji domain containing 6, arginine demethylase and lysine hydroxylase | Q21109634 | ||
| snRNA modification | Q21120833 | ||
| Methylphosphate capping enzyme | Q21120834 | ||
| P304 | page(s) | 1581-1595 | |
| P577 | publication date | 2013-12-19 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release | |
| P478 | volume | 155 |
| Q47935959 | 7SK small nuclear RNA, a multifunctional transcriptional regulatory RNA with gene-specific features. |
| Q37170897 | 7SK-BAF axis controls pervasive transcription at enhancers |
| Q37130418 | 7SKiing on chromatin: Move globally, act locally |
| Q34486331 | A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat |
| Q34045819 | A Primitive Growth Factor, NME7AB , Is Sufficient to Induce Stable Naïve State Human Pluripotency; Reprogramming in This Novel Growth Factor Confers Superior Differentiation. |
| Q39356451 | A generative model for the behavior of RNA polymerase |
| Q38226685 | A mechanistic link between gene regulation and genome architecture in mammalian development |
| Q33574512 | Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer |
| Q88514325 | Amazing Diversity in Biochemical Roles of Fe(II)/2-Oxoglutarate Oxygenases |
| Q34531812 | Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases |
| Q35818709 | Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation |
| Q90202160 | Assaying epigenome functions of PRMTs and their substrates |
| Q36818327 | BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements |
| Q52697946 | BET Family Protein BRD4: An Emerging Actor in NFκB Signaling in Inflammation and Cancer. |
| Q38760291 | BET Proteins: An Approach to Future Therapies in Transplantation. |
| Q41904871 | BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes. |
| Q99569291 | BET bromodomains as novel epigenetic targets for brain health and disease |
| Q38779981 | BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells. |
| Q36575895 | BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice |
| Q59333141 | BRD4 and Cancer: going beyond transcriptional regulation |
| Q36485411 | BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones |
| Q34046783 | BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin |
| Q38744593 | BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire. |
| Q98471230 | BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage |
| Q38674128 | Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story. |
| Q92418215 | Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6 |
| Q38743834 | Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations |
| Q91936795 | Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production |
| Q93111060 | Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway |
| Q35670978 | Bromodomain inhibitors regulate the C9ORF72 locus in ALS |
| Q36561822 | Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription |
| Q60054289 | Bromodomain protein inhibition: a novel therapeutic strategy in rheumatic diseases |
| Q47111692 | CDK9-dependent RNA polymerase II pausing controls transcription initiation |
| Q59352420 | CDK9: a signaling hub for transcriptional control |
| Q38633555 | CIPHER: a flexible and extensive workflow platform for integrative next-generation sequencing data analysis and genomic regulatory element prediction |
| Q48210831 | Cancer: Keeping it real to kill glioblastoma |
| Q40494787 | Chromatin Architecture of the Pitx2 Locus Requires CTCF- and Pitx2-Dependent Asymmetry that Mirrors Embryonic Gut Laterality. |
| Q47894270 | Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. |
| Q38756638 | Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors. |
| Q35814984 | Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism |
| Q34445315 | Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization |
| Q28276848 | Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb |
| Q38995028 | Cyclin-dependent kinases as therapeutic targets for HIV-1 infection. |
| Q96641354 | Dissecting the Pol II transcription cycle and derailing cancer with CDK inhibitors |
| Q36158104 | Dynamic enhancer-gene body contacts during transcription elongation |
| Q48863076 | Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex. |
| Q26740004 | Epigenetic memory: A macrophage perspective |
| Q47132107 | Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. |
| Q50055595 | FRET Image Correlation Spectroscopy Reveals RNAPII-Independent P-TEFb Recruitment on Chromatin. |
| Q36794841 | Functional interplay between PPM1G and the transcription elongation machinery |
| Q28257378 | Functions of BET proteins in erythroid gene expression |
| Q36199553 | GC skew defines distinct RNA polymerase pause sites in CpG island promoters |
| Q52849456 | Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription. |
| Q92545555 | General mechanism of JQ1 in inhibiting various types of cancer |
| Q90482460 | Genome-Wide Maps of Transcription Regulatory Elements and Transcription Enhancers in Development and Disease |
| Q36652760 | Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II. |
| Q36790684 | Global gene expression profiling of JMJD6- and JMJD4-depleted mouse NIH3T3 fibroblasts |
| Q46081306 | Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program. |
| Q36529956 | H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus |
| Q90570888 | HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb |
| Q47624813 | Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1. |
| Q26777269 | Histone demethylases in chromatin biology and beyond |
| Q28082123 | Histone methylation modifiers in cellular signaling pathways |
| Q39042647 | Hypertranscription in Development, Stem Cells, and Regeneration. |
| Q41621328 | Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer |
| Q64098224 | Integrative modeling reveals key chromatin and sequence signatures predicting super-enhancers |
| Q38626078 | Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. |
| Q52328749 | JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex. |
| Q33558243 | JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner. |
| Q89673835 | JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes |
| Q48139415 | JMJD6 induces HOTAIR, an oncogenic lincRNA, by physically interacting with its proximal promoter. |
| Q92185923 | JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma |
| Q92266857 | JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity |
| Q35953126 | JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis |
| Q37703058 | Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic Functions |
| Q42719872 | Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins |
| Q90862808 | Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer |
| Q92795815 | Jumonji domain-containing protein 6 protein and its role in cancer |
| Q36467037 | KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II. |
| Q37031949 | Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy |
| Q36419269 | Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction |
| Q40969997 | Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II. |
| Q89756562 | Mechanistic basis and efficacy of targeting β-catenin-TCF7L2-JMJD6-MYC axis to overcome resistance to BET inhibitors |
| Q64903148 | Mediator complex interaction partners organize the transcriptional network that defines neural stem cells. |
| Q42750070 | Megakaryocytic irreversible P-TEFb activation |
| Q58381515 | Methylarginine Recognition by Tudor Domains |
| Q42778389 | Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation. |
| Q34556377 | Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation |
| Q35280127 | Myosin VI regulates gene pairing and transcriptional pause release in T cells |
| Q36395823 | NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. |
| Q42776375 | Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice |
| Q49455798 | Non-Coding RNAs As Transcriptional Regulators In Eukaryotes. |
| Q35218913 | Non-coding RNA: a new frontier in regulatory biology |
| Q58797199 | Normalizing JMJD6 Expression in Rat Spinal Dorsal Horn Alleviates Hyperalgesia Following Chronic Constriction Injury |
| Q47099658 | Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes |
| Q51032114 | Orphan CpG islands define a novel class of highly active enhancers. |
| Q64092997 | P-TEFb Regulates Transcriptional Activation in Non-coding RNA Genes |
| Q48335211 | P-TEFb: Finding its ways to release promoter-proximally paused RNA polymerase II. |
| Q37507609 | PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6. |
| Q36174095 | PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation. |
| Q58090240 | PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma |
| Q58726533 | Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex |
| Q92726769 | Promotion of adipogenesis by JMJD6 requires the AT hook-like domain and is independent of its catalytic function |
| Q34483921 | Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases |
| Q38935888 | Protein arginine methylation/demethylation and cancer |
| Q39212312 | Protein arginine methylation: a prominent modification and its demethylation |
| Q64926874 | Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. |
| Q55221792 | Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy. |
| Q46266835 | R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters. |
| Q37042217 | RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation |
| Q30740300 | RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription |
| Q24308066 | RNA helicase DDX21 coordinates transcription and ribosomal RNA processing |
| Q91626679 | RNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome |
| Q60949674 | Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression |
| Q30359633 | Readers of histone methylarginine marks. |
| Q33878635 | Reconstitution of a functional 7SK snRNP |
| Q34178834 | Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection |
| Q36605841 | Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation |
| Q35581589 | Role of JMJD6 in Breast Tumourigenesis. |
| Q88727236 | SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription |
| Q49830811 | Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. |
| Q47116460 | Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4. |
| Q36646571 | Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction |
| Q26745666 | Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases |
| Q28263519 | Targeting BET bromodomains for cancer treatment |
| Q39141456 | Targeting Cancer Cells with BET Bromodomain Inhibitors |
| Q47385983 | Targeting bromodomain and extraterminal proteins in breast cancer |
| Q34421279 | Targeting histone lysine demethylases - progress, challenges, and the future |
| Q38309696 | Technologies to probe functions and mechanisms of long noncoding RNAs |
| Q33606391 | The "histone mimicry" by pathogens |
| Q28073961 | The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins |
| Q37522950 | The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation. |
| Q57491556 | The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism |
| Q92207058 | The emerging role of mediator complex subunit 12 in tumorigenesis and response to chemotherapeutics |
| Q29544441 | The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis |
| Q28241504 | The mechanisms behind the therapeutic activity of BET bromodomain inhibition |
| Q52680700 | The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML. |
| Q38495832 | The oxygenase Jmjd6--a case study in conflicting assignments |
| Q90745873 | The role of phosphatidylserine recognition receptors in multiple biological functions |
| Q28081960 | The selection and function of cell type-specific enhancers |
| Q91607539 | The small members of the JMJD protein family: Enzymatic jewels or jinxes? |
| Q41858982 | The transcriptional regulator Aire binds to and activates super-enhancers |
| Q37194356 | Transcription elongation control by the 7SK snRNP complex: Releasing the pause. |
| Q48731754 | Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. |
| Q36299124 | Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6. |
| Q38288525 | Twist-BRD4 complex: potential drug target for basal-like breast cancer |
Search more.