| scholarly article | Q13442814 |
| P50 | author | Nick Grishin | Q21339744 |
| P2093 | author name string | Lisa N Kinch | |
| Richard K Bruick | |||
| Qiming Li | |||
| Ameen A Salahudeen | |||
| Joel W Thompson | |||
| Julio C Ruiz | |||
| He-Wen Ma | |||
| P2860 | cites work | Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2 | Q24297533 |
| FBXL5 interacts with p150Glued and regulates its ubiquitination | Q24307388 | ||
| Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation | Q24309350 | ||
| Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2 | Q24597762 | ||
| A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA | Q24614690 | ||
| Using circular dichroism spectra to estimate protein secondary structure | Q24650518 | ||
| Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network | Q28280607 | ||
| Iron Regulates the Intracellular Degradation of Iron Regulatory Protein 2 by the Proteasome | Q28581495 | ||
| Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster | Q28594612 | ||
| A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin | Q29618006 | ||
| Balancing acts: molecular control of mammalian iron metabolism | Q29620380 | ||
| Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity | Q35544553 | ||
| Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism | Q35596995 | ||
| Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins | Q36060093 | ||
| Hemochromatosis: genetics and pathophysiology | Q36366870 | ||
| Molecular control of vertebrate iron homeostasis by iron regulatory proteins | Q36536936 | ||
| The role of iron regulatory proteins in mammalian iron homeostasis and disease | Q36540433 | ||
| Diversity and distribution of hemerythrin-like proteins in prokaryotes | Q37032870 | ||
| Iron homeostasis and erythropoiesis | Q37087636 | ||
| Thinking outside the F-box: novel ligands for novel receptors | Q37414804 | ||
| A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation | Q39887736 | ||
| HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells | Q40083984 | ||
| Oxygen and iron regulation of iron regulatory protein 2. | Q44530905 | ||
| The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2. | Q44583463 | ||
| Dioxygen and Hemerythrin | Q55924126 | ||
| Reconstitution of the diiron sites in hemerythrin and myohemerythrin | Q68183330 | ||
| P433 | issue | 5953 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | iron | Q677 |
| iron ion homeostasis | Q14860561 | ||
| F-box and leucine rich repeat protein 5 | Q21101381 | ||
| P304 | page(s) | 722-6 | |
| P577 | publication date | 2009-10-30 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis | |
| P478 | volume | 326 |
| Q36545176 | A Bacterial Hemerythrin Domain Regulates the Activity of a Vibrio cholerae Diguanylate Cyclase |
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| Q34903557 | A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice. |
| Q41685395 | A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation |
| Q50543530 | A tetrapyrrole-regulated ubiquitin ligase controls algal nuclear DNA replication. |
| Q27330107 | Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments |
| Q42947662 | Abscisic Acid Increases Arabidopsis ABI5 Transcription Factor Levels by Promoting KEG E3 Ligase Self-Ubiquitination and Proteasomal Degradation |
| Q55078174 | Acute loss of iron-sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells. |
| Q55497286 | Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer. |
| Q36864880 | An emerging role for Cullin-3 mediated ubiquitination in sleep and circadian rhythm: insights from Drosophila. |
| Q39007031 | Animal models of RLS phenotypes |
| Q92623850 | Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling |
| Q91742101 | Association between Fbxl5 gene polymorphisms and partial economic traits in Jinghai Yellow chickens |
| Q41468619 | Association of hepatic oxidative stress and iron dysregulation with HCC development after interferon therapy in chronic hepatitis C. |
| Q50941609 | BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana |
| Q47862572 | Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways |
| Q37605018 | Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities |
| Q50299637 | CUL1, SKP1, FBXL5 bind |
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| Q41685377 | Checks and balances for the iron bank. |
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| Q36926625 | Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation |
| Q34785767 | Cullin E3 ligases and their rewiring by viral factors |
| Q34022066 | Dealing with oxidative stress and iron starvation in microorganisms: an overview |
| Q35832047 | Deciphering Mineral Homeostasis in Barley Seed Transfer Cells at Transcriptional Level |
| Q36602744 | Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. |
| Q30278581 | Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis |
| Q37928941 | Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice |
| Q92402516 | Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis |
| Q89995926 | Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism |
| Q34614742 | Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levels |
| Q35585864 | Duodenal cytochrome b (DCYTB) in iron metabolism: an update on function and regulation. |
| Q38219400 | Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation. |
| Q37947588 | Dysregulation of iron metabolism in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. |
| Q50330359 | Endogenous bone regeneration is dependent upon a dynamic oxygen event |
| Q92860081 | Environmental arginine controls multinuclear giant cell metabolism and formation |
| Q41077865 | Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells. |
| Q36508718 | F-box and Leucine-rich Repeat Protein 5 (FBXL5) Is Required for Maintenance of Cellular and Systemic Iron Homeostasis |
| Q37648177 | F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen |
| Q90746433 | F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects |
| Q41662124 | FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells |
| Q89998876 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster |
| Q38991027 | FBXL5 targets cortactin for ubiquitination-mediated destruction to regulate gastric cancer cell migration |
| Q34313139 | FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response |
| Q34274947 | Fe 2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation |
| Q34778885 | Ferritin protein nanocages use ion channels, catalytic sites, and nucleation channels to manage iron/oxygen chemistry |
| Q36119759 | Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. |
| Q51008237 | Ferroptosis: A Novel Anti-Tumor Action for Cisplatin |
| Q89888349 | Ferroptosis: Final destination for cancer? |
| Q34032093 | Ferroptosis: an iron-dependent form of nonapoptotic cell death |
| Q45248744 | Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes. |
| Q37255130 | Further insight into BRUTUS domain composition and functionality. |
| Q44785565 | GDF15‐mediated upregulation of ferroportin plays a key role in the development of hyperferritinemia in children with hemophagocytic lymphohistiocytosis |
| Q33558892 | Getting a sense for signals: Regulation of the plant iron deficiency response |
| Q40371290 | HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism |
| Q24299064 | Haem oxygenase-1 overexpression alters intracellular iron distribution |
| Q64257858 | Hemerythrin E3 Ubiquitin Ligases as Negative Regulators of Iron Homeostasis in Plants |
| Q36078813 | Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms |
| Q27002595 | Hepcidin and iron homeostasis |
| Q34785418 | High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats |
| Q33759166 | High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. |
| Q37201948 | Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins |
| Q24634143 | Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease |
| Q37761566 | Hyperferritinaemia-cataract syndrome: worldwide mutations and phenotype of an increasingly diagnosed genetic disorder |
| Q30273595 | Hypoxia Inducible Factor-2a Is Translationally Repressed in Response to Dietary Iron Deficiency in Sprague-Dawley Rats |
| Q24609166 | Hypoxic regulation of erythropoiesis and iron metabolism |
| Q38248244 | IRE mRNA riboregulators use metabolic iron (Fe(2+)) to control mRNA activity and iron chemistry in animals |
| Q35207735 | IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease |
| Q50897468 | IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation |
| Q42430117 | Identification of a hemerythrin-like domain in a P1B-type transport ATPase |
| Q37083811 | Influence of microRNA on the Maintenance of Human Iron Metabolism |
| Q43009519 | Interaction of iron regulatory protein-1 (IRP-1) with ATP/ADP maintains a non-IRE-binding state |
| Q42084921 | Intracellular iron sensing by the direct binding of iron to regulators |
| Q35067691 | Iron Regulatory Protein 1 Outcompetes Iron Regulatory Protein 2 in Regulating Cellular Iron Homeostasis in Response to Nitric Oxide |
| Q35084985 | Iron Regulatory Protein 2 Turnover through a Nonproteasomal Pathway |
| Q35627033 | Iron Responsive mRNAs: A Family of Fe2+ Sensitive Riboregulators |
| Q64102472 | Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells |
| Q35214752 | Iron and Immunity: Immunological Consequences of Iron Deficiency and Overload |
| Q41260893 | Iron and copper in mitochondrial diseases |
| Q33349194 | Iron and porphyrin trafficking in heme biogenesis |
| Q100406084 | Iron chaperone PCBP1 protects murine liver from lipid peroxidation and steatosis |
| Q27318323 | Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice |
| Q37691483 | Iron metabolism in trypanosomatids, and its crucial role in infection |
| Q38007163 | Iron metabolism: interactions with normal and disordered erythropoiesis |
| Q36053170 | Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins |
| Q91651434 | Iron regulatory protein 2 modulates the switch from aerobic glycolysis to oxidative phosphorylation in mouse embryonic fibroblasts |
| Q55128126 | Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts. |
| Q37635844 | Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria |
| Q38259243 | Iron regulatory proteins and their role in controlling iron metabolism |
| Q38066761 | Iron speciation in the cytosol: an overview |
| Q41845557 | Iron transport through ferroportin is induced by intracellular ascorbate and involves IRP2 and HIF2α. |
| Q44876499 | Iron-binding E3 ligase mediates iron response in plants by targeting basic helix-loop-helix transcription factors |
| Q37528295 | Iron-binding haemerythrin RING ubiquitin ligases regulate plant iron responses and accumulation. |
| Q38912921 | Iron-dependent turnover of IRP-1/c-aconitase in kidney cells. |
| Q47164877 | Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth |
| Q92668716 | Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification |
| Q37618839 | Maintaining Mammalian iron and oxygen homeostasis: sensors, regulation, and cross-talk |
| Q38063952 | Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action |
| Q36910294 | Mammalian iron metabolism and its control by iron regulatory proteins |
| Q37307464 | Mechanisms and function of substrate recruitment by F-box proteins. |
| Q64100829 | Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review |
| Q27010510 | Mechanisms of Mammalian Iron Homeostasis |
| Q33658871 | Mechanisms of iron metabolism in Caenorhabditis elegans |
| Q30418431 | Membrane Protein Structure Predictions for Exploration |
| Q37750239 | Mitochondrial iron metabolism and its role in neurodegeneration. |
| Q34565537 | Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C. |
| Q27009565 | Murine mutants in the study of systemic iron metabolism and its disorders: An update on recent advances |
| Q36827099 | Negative feedback regulation of the yeast CTH1 and CTH2 mRNA binding proteins is required for adaptation to iron deficiency and iron supplementation. |
| Q37518650 | Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability |
| Q39179833 | Overview of iron metabolism in health and disease |
| Q61807132 | Oxidative Stress Regulated Iron Regulatory Protein IRP2 Through FBXL5-Mediated Ubiquitination-Proteasome Way in SH-SY5Y Cells |
| Q33897916 | Oxygen sensing strategies in mammals and bacteria. |
| Q39625518 | POSITIVE REGULATOR OF IRON HOMEOSTASIS1, OsPRI1, Facilitates Iron Homeostasis. |
| Q38681448 | Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. |
| Q93200047 | Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2 |
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| Q37139091 | Post-transcriptional regulation of iron homeostasis in Saccharomyces cerevisiae. |
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