Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M508660200
P3181OpenCitations bibliographic resource ID1076394
P698PubMed publication ID16118205

P50authorMathias ZieglerQ42723114
Corinna LauQ79949782
Mathias DahlmannQ81104533
P2093author name stringFelicitas Berger
P2860cites workTankyrase, a poly(ADP-ribose) polymerase at human telomeresQ22008022
Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferaseQ24290390
Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesisQ24290921
Structural and functional characterization of human NAD kinaseQ24291777
Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 proteinQ24304101
Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreasQ24530614
Functional aspects of protein mono-ADP-ribosylationQ24675892
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasisQ27636976
Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurinQ27637274
Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMNQ27638867
Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesisQ27640452
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiaeQ27933365
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levelsQ27933382
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humansQ27937147
A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiaeQ27937404
Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzymeQ27938021
Identification of a novel human nicotinamide mononucleotide adenylyltransferaseQ28118710
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegansQ28131824
Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesiclesQ28138791
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanQ28203572
Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouseQ28206635
Biochemistry, biology, and pharmacology of cyclic adenosine diphosphoribose (cADPR)Q28255928
The Sir2 family of protein deacetylasesQ28266179
The Escherichia coli NadR regulator is endowed with nicotinamide mononucleotide adenylyltransferase activityQ28611173
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degenerationQ29616075
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functionsQ29617672
The new life of a centenarian: signalling functions of NAD(P).Q33976408
Tannins elevate the level of poly(ADP-ribose) in HeLa cell extracts.Q33977475
Pathophysiological relevance of mitochondria in NAD(+) metabolism.Q34180523
Cyclic ADP ribose as a calcium-mobilizing messengerQ34467662
The therapeutic potential of poly(ADP-ribose) polymerase inhibitorsQ34838585
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouseQ35286946
Multiplicity of Ca2+ messengers and Ca2+ stores: a perspective from cyclic ADP-ribose and NAADP.Q35752797
Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP-ribose) metabolismQ40585232
Nicotinamide-mononucleotide adenylyltransferase from Methanococcus jannaschii.Q42645699
Identification of the archaeal NMN adenylytransferase geneQ43026453
Nicotinamide-mononucleotide adenylyltransferase from Sulfolobus solfataricusQ43551718
Cloning and characterization of two NAD kinases from Arabidopsis. identification of a calmodulin binding isoformQ44973391
ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose).Q52970520
NAD biosynthesis in human placenta: purification and characterization of homogeneous NMN adenylyltransferaseQ68043928
Novel inhibitors of poly(ADP-ribose) glycohydrolaseQ72634399
21 Purification of human nicotinamide-mononucleotide adenylyltransferaseQ73484761
Neuroscience. NAD to the rescueQ80450186
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectniacinamideQ192423
nucleotide biosynthetic processQ14819381
Nicotinamide nucleotide adenylyltransferase 1Q21109679
nicotinamide nucleotide adenylyltransferase 3Q21118870
Nicotinamide nucleotide adenylyltransferase 2Q21118871
P304page(s)36334-36341
P577publication date2005-08-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleSubcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
P478volume280

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