Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte

scientific article

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/0008-5472.CAN-08-4554
P932PMC publication ID2869030
P698PubMed publication ID19491264
P5875ResearchGate publication ID26261834

P50authorSøren BrunakQ7666528
Niels E. SkakkebækQ12328758
Agnieszka Sierakowska JunckerQ42577755
Lise Mette GjerdrumQ47367382
Si Brask SonneQ47367399
Ewa Rajpert-De MeytsQ47367417
Marlene D DalgaardQ96952697
Henrik LeffersQ114439668
Kristian AlmstrupQ38548487
P2093author name stringPeter W Andrews
Amir Abdollahi
Peter E Huber
Harry D Moore
Christian Schwager
Ludmila Ruban
Neil J Harrison
Daniel Edsgard
P2860cites workIntermediate filament proteins in human testis and testicular germ-cell tumors.Q42752909
A monoclonal antibody as a marker for carcinoma in situ germ cells of the human adult testis.Q45239019
Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis.Q48186528
A receptor-type protein tyrosine phosphatase PTP zeta is expressed in human cutaneous melanomas.Q52169238
Expression of anti-Müllerian hormone during normal and pathological gonadal development: association with differentiation of Sertoli and granulosa cells.Q52173957
Light and electron microscopical analysis of cell types in human seminoma.Q54072426
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.Q54709833
Gene expression profiling identifies new biological markers of neoplastic germ cellsQ58194332
Co-expression of cytokeratin and vimentin filaments in mesothelial, granulosa and rete ovarii cells of the human ovaryQ58439218
Genome profiles of familial/bilateral and sporadic testicular germ cell tumorsQ59273315
Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumoursQ60501370
Aneuploidy as a marker for carcinoma-in-situ of the testisQ70748539
Carcinoma-in-situ of the undescended testisQ72540601
Overrepresentation of the short arm of chromosome 12 is related to invasive growth of human testicular seminomas and nonseminomasQ73322458
Possible carcinoma-in-situ of the testisQ93727453
Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimesterQ24293254
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoformsQ24317415
Significance analysis of microarrays applied to the ionizing radiation responseQ24606608
Multiclass classification of microarray data with repeated measurements: application to cancerQ24793866
Fetal antigen 1, an EGF multidomain protein in the sex hormone-producing cells of the gonads and the microenvironment of germ cellsQ28145426
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumoursQ28258587
TM4: a free, open-source system for microarray data management and analysisQ29547339
Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspectsQ29615676
Expression of protamine-1 and -2 mRNA during human spermiogenesisQ30842604
High-resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor developmentQ30978523
Role of gain of 12p in germ cell tumour developmentQ33187052
Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells.Q33204298
FOXL2 and SOX9 as parameters of female and male gonadal differentiation in patients with various forms of disorders of sex development (DSD).Q33324250
Optimizing staining protocols for laser microdissection of specific cell types from the testis including carcinoma in situQ33444788
Genetics and biology of adult human male germ cell tumors.Q33882329
Carcinoma in situ in the testisQ34122634
POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumorsQ34194341
Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonadsQ34315876
Identification and characterization of ASXL3 gene in silico.Q34320220
Identification, characterization, and evolution of a primate beta-defensin gene clusterQ34623458
Generation of pluripotent stem cells from adult human testis.Q34851175
The emerging phenotype of the testicular carcinoma in situ germ cellQ35129514
Early manifestations of testicular dysgenesis in children: pathological phenotypes, karyotype correlations and precursor stages of tumour developmentQ35132939
Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiersQ36492858
The stem cell identity of testicular cancerQ36943376
Testicular dysgenesis syndrome and the origin of carcinoma in situ testisQ37060508
Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effectsQ37097242
Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal developmentQ38324122
Dysfunction of the mitotic:meiotic switch as a potential cause of neoplastic conversion of primordial germ cellsQ40319110
Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.Q40476342
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cellsQ40544422
Anti-MIC2 as a tool in examination of testicular biopsiesQ40802345
Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical studyQ41545531
Expression of immunohistochemical markers for testicular carcinoma in situ by normal human fetal germ cells.Q41664542
P4510describes a project that useslimmaQ112236343
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)5241-5250
P577publication date2009-06-02
P1433published inCancer ResearchQ326097
P1476titleAnalysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte
P478volume69

Reverse relations

cites work (P2860)
Q41434285A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation
Q37688873A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment.
Q34247366A unique combination of male germ cell miRNAs coordinates gonocyte differentiation
Q34692315An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism
Q39781684Analysis of SOX2 expression in developing human testis and germ cell neoplasia
Q24296808Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry
Q90208432Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours
Q38838783Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives
Q39949220Baldness and testicular cancer: the EPSAM case-control study
Q54598067Cancer testis antigen expression in testicular germ cell tumorigenesis.
Q42007600Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells
Q34464888Cellular and molecular effect of MEHP Involving LXRα in human fetal testis and ovary.
Q38172901Cellular evidence for selfish spermatogonial selection in aged human testes
Q35021459Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential
Q38883739Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents
Q41820355Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors.
Q43009263Cryptorchidism: pathogenesis, diagnosis, treatment and prognosis
Q36868543Current Management of Undescended Testes
Q33783200Custom human endogenous retroviruses dedicated microarray identifies self-induced HERV-W family elements reactivated in testicular cancer upon methylation control.
Q37288260Developmental reprogramming of cancer susceptibility
Q33896475Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance
Q45720545Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ
Q39367088Establishment of a versatile seminoma model indicates cellular plasticity of germ cell tumor cells.
Q34396787Etiologic factors in testicular germ-cell tumors
Q41918113Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis
Q40447381Genomic evolution and chemoresistance in germ-cell tumours.
Q39082280Germ cell tumors: Insights from the Drosophila ovary and the mouse testis
Q39669544Heterochromatin marks HP1γ, HP1α and H3K9me3, and DNA damage response activation in human testis development and germ cell tumours
Q33940047Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information
Q37383318Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors.
Q36715639Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice.
Q38555758Intratubular Germ Cell Neoplasia of the Testis, Bilateral Testicular Cancer, and Aberrant Histologies.
Q37763851Intratubular germ cell neoplasms of the testis and bilateral testicular tumors: clinical significance and management options
Q38861307Investigational targeted therapies for the treatment of testicular germ cell tumors
Q38535583Involvement of epigenetic modifiers in the pathogenesis of testicular dysgenesis and germ cell cancer
Q51820656Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours.
Q48229862Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?
Q33502381Laser capture microdissection of gonads from juvenile zebrafish.
Q34502168Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility
Q30904724Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union
Q91660922Management, Treatment, and Molecular Background of the Growing Teratoma Syndrome
Q40163628Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.
Q39646985NANOG promoter methylation and expression correlation during normal and malignant human germ cell development
Q38984619OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia
Q93062279On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer
Q33444788Optimizing staining protocols for laser microdissection of specific cell types from the testis including carcinoma in situ
Q33930933Organochlorine compounds and testicular dysgenesis syndrome: human data
Q40046878Parental Occupational Exposure to Organic Solvents and Testicular Germ Cell Tumors in their Offspring: NORD-TEST Study
Q34378988Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors
Q38366531Recent adverse trends in semen quality and testis cancer incidence among Finnish men.
Q35617326Retinoblastoma protein (RB1) controls fate determination in stem cells and progenitors of the mouse male germline.
Q36289256Significant calendar period deviations in testicular germ cell tumors indicate that postnatal exposures are etiologically relevant
Q57809760Sperm imprinting integrity in seminoma patients?
Q41077105Spontaneous CD4+ and CD8+ T-cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients
Q47231034Testicular cancer from diagnosis to epigenetic factors
Q38184375Testicular cancer: biology and biomarkers
Q86879831Testicular germ cell tumours
Q38410131Testicular germ cell tumours in dogs are predominantly of spermatocytic seminoma type and are frequently associated with somatic cell tumours
Q37337141The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment
Q38975123The biology of germ cell tumors in disorders of sex development
Q38756704The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas
Q39180884The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis
Q39154300The plasticity of germ cell cancers and its dependence on the cellular microenvironment.
Q37513681The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets.
Q37874665The role of BLIMP1 and its putative downstream target TFAP2C in germ cell development and germ cell tumours.
Q39408223The role of vitamin D in male fertility: A focus on the testis
Q37886262The testicular germ cell tumour transcriptome
Q41498099Transcriptome profiling of mice testes following low dose irradiation
Q38145508Unravelling mechanisms of cisplatin sensitivity and resistance in testicular cancer.
Q52725335Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer.
Q29392883Vitamin D and male reproduction
Q42407720Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
Q39762519Will Testicular Germ Cell Tumors Remain Untargetable?
Q26992374miRNA and mammalian male germ cells

Search more.