The stem cell identity of testicular cancer

scientific article published on January 2007

The stem cell identity of testicular cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S12015-007-0002-X
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s12015-007-0002-x
P698PubMed publication ID17873381

P2093author name stringAmander T Clark
P2860cites workMalignant teratoma of the testis with an isochromosome no. 12, i(12p), as the sole structural cytogenetic abnormalityQ71304009
Primordial germ cell proliferation in fetal testes in mouse strains with high and low incidences of congenital testicular teratomasQ72049958
Origin of testicular teratomas from primordial germ cells in miceQ72220143
Involvement of the D-type cyclins in germ cell proliferation and differentiation in the mouseQ73221298
Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogoniaQ73222420
Histochemical observations on the germ cells of human embryosQ73322110
Up-regulation of cyclin-dependent kinase 4/cyclin D2 expression but down-regulation of cyclin-dependent kinase 2/cyclin E in testicular germ cell tumorsQ73894025
Altered expression of connexins 26 and 43 in Sertoli cells in seminiferous tubules infiltrated with carcinoma-in-situ or seminomaQ74717653
A description of spontaneous congenital testicular teratomas in strain 129 miceQ74786531
Alteration of Sertoli cell differentiation in the presence of carcinoma in situ in human testesQ77449385
Cadherin-mediated cell interaction regulates germ cell determination in miceQ79308335
The biology of teratomas including evidence indicating their origin form primordial germ cellsQ79646338
Analysis of the mRNA expression of the TGF-Beta family in testicular cells and localization of the splice variant TGF-beta2B in testisQ79991870
Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumorQ81589836
Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumorsQ82310193
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in miceQ21284146
Core transcriptional regulatory circuitry in human embryonic stem cellsQ24322016
Germline transmission of donor haplotype following spermatogonial transplantationQ24562062
Requirement of Bmp8b for the generation of primordial germ cells in the mouseQ28140750
Severely reduced female fertility in CD9-deficient miceQ28142603
Establishment of the paternal methylation imprint of the human H19 and MEST/PEG1 genes during spermatogenesisQ28144502
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cellsQ28176663
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cellsQ28176681
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouseQ28201223
GDF3 at the crossroads of TGF-beta signalingQ28242021
Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinomaQ28247441
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumoursQ28258587
Biomarker discovery from pancreatic cancer secretome using a differential proteomic approachQ28276398
Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changesQ28278756
Nanog and transcriptional networks in embryonic stem cell pluripotencyQ28282505
GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryosQ28285917
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryoQ28288038
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouseQ28296363
A novel family of TEA domain-containing transcription factors with distinct spatiotemporal expression patternsQ28296789
Primordial germ cells in the mouse embryo during gastrulationQ28305754
Clonal analysis of the origin of primordial germ cells in the mouseQ28306211
PGC7/Stella protects against DNA demethylation in early embryogenesisQ28506319
Oct-4: a germline-specific transcription factor mapping to the mouse t-complexQ28506545
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprintingQ28508038
Multipotent cell lineages in early mouse development depend on SOX2 functionQ28513175
Effects of TGF-betas and a specific antagonist on apoptosis of immature rat male germ cells in vitroQ28572657
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumoursQ28586692
Plzf is required in adult male germ cells for stem cell self-renewalQ28588440
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cellsQ28589532
Expression and intracellular localization of mouse Vasa-homologue protein during germ cell developmentQ28594431
Oct4 is required for primordial germ cell survivalQ28594875
Induction of Tumors in Mice by Genomic HypomethylationQ29618551
Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminomaQ33180567
VASA is a specific marker for both normal and malignant human germ cellsQ33183392
Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cellsQ33186939
Testicular germ-cell tumours in a broader perspective.Q33212387
Comparative gene expression analysis of ovarian carcinoma and normal ovarian epithelium by serial analysis of gene expressionQ33219956
Establishing clonal cell lines with endothelial-like potential from CD9(hi), SSEA-1(-) cells in embryonic stem cell-derived embryoid bodiesQ33267318
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineagesQ34075246
All you wanted to know about spermatogonia but were afraid to ask.Q34098490
Stella is a maternal effect gene required for normal early development in miceQ34280753
Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cellsQ34364153
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesisQ34409582
Pluripotency of spermatogonial stem cells from adult mouse testisQ34505738
Transition from preinvasive carcinoma in situ to seminoma is accompanied by a reduction of connexin 43 expression in Sertoli cells and germ cellsQ35082204
Deregulation of the G1/S-phase control in human testicular germ cell tumoursQ35132963
The human VASA gene is specifically expressed in the germ cell lineageQ35209388
X inactivation in human testicular tumors. XIST expression and androgen receptor methylation statusQ35763875
Spermatogenesis following male germ-cell transplantationQ35907473
The ADAM-integrin-tetraspanin complex in fetal and postnatal testicular cordsQ36202500
Genetic alterations in urothelial bladder carcinoma: an updated reviewQ36393012
Gamete imprinting: setting epigenetic patterns for the next generationQ36396477
Testicular germ-cell cancer.Q36414006
Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumorsQ36733260
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumorsQ37089250
Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal developmentQ38324122
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cellsQ38361122
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phaseQ40232134
CD30 is a survival factor and a biomarker for transformed human pluripotent stem cellsQ40311485
Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinomaQ40361266
Global loss of imprinting leads to widespread tumorigenesis in adult miceQ40361864
Analysis of Esg1 expression in pluripotent cells and the germline reveals similarities with Oct4 and Sox2 and differences between human pluripotent cell linesQ40372936
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cellsQ40544422
Culture conditions and single growth factors affect fate determination of mouse spermatogonial stem cellsQ40561530
Spontaneous differentiation of germ cells from human embryonic stem cells in vitroQ40590096
p27 and cyclin E/D2 associations in testicular germ cell tumors: implications for tumorigenesis.Q40643563
Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells1Q40654689
Glial cell line-derived neurotrophic factor (GDNF) and its receptors GFRalpha-1 and GFRalpha-2 in the human testis.Q40765312
Promotion of seminomatous tumors by targeted overexpression of glial cell line-derived neurotrophic factor in mouse testisQ40812044
Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical studyQ41545531
The ultrastructure of human reproduction. I. The natural history of the female germ cell: origin, migration and differentiation inside the developing ovaryQ41606381
Generation of pluripotent stem cells from neonatal mouse testisQ42801351
Morphological characterization of the spermatogonial subtypes in the neonatal mouse testisQ44509680
Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells.Q45935029
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.Q47694289
The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell developmentQ47811571
From carcinoma in situ to testicular germ cell tumourQ47845149
Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1.Q48010127
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.Q48547495
A molecular programme for the specification of germ cell fate in mice.Q48558286
Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice.Q50779221
Nanog expression in mouse germ cell development.Q51442473
Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions.Q51566448
Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling.Q52011445
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.Q52108303
The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo.Q52200224
A novel SMAD4 gene mutation in seminoma germ cell tumors.Q52538272
Increasing incidence of testicular germ cell tumors among black men in the United States.Q53660843
Experimental induction of testicular teratomas in dissociated-reaggregated chimaeric gonads.Q54508612
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.Q54709833
Equivalent parental distribution of frequently lost alleles and biallelic expression of the H19 gene in human testicular germ cell tumors.Q55234318
Requirement ofBmp8bfor the Generation of Primordial Germ Cells in the MouseQ55884159
Epigenetic reprogramming in mouse primordial germ cellsQ57086629
Spatial expression of germ cell markers during maturation of human fetal male gonads: an immunohistochemical studyQ58194341
Immunohistochemical Profiling of Germ Cells Within the Human Fetal Testis: Identification of Three SubpopulationsQ64460532
A recessive mutation (ter) causing germ cell deficiency and a high incidence of congenital testicular teratomas in 129/Sv-ter miceQ69841641
i(12p): specific chromosomal marker in seminoma and malignant teratoma of the testis?Q71030066
P433issue1
P304page(s)49-59
P577publication date2007-01-01
P1433published inStem Cell Reviews and ReportsQ7607285
P1476titleThe stem cell identity of testicular cancer
P478volume3

Reverse relations

cites work (P2860)
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Q33459014Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte
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