scholarly article | Q13442814 |
P356 | DOI | 10.1126/SCIENCE.1083558 |
P953 | full work available at URL | https://syndication.highwire.org/content/doi/10.1126/science.1083558 |
P3181 | OpenCitations bibliographic resource ID | 57157 |
P698 | PubMed publication ID | 12702876 |
P5875 | ResearchGate publication ID | 10797813 |
P50 | author | Rudolf Jaenisch | Q90073 |
P2093 | author name string | Heinrich Leonhardt | |
Amir Eden | |||
Joe W. Gray | |||
François Gaudet | |||
Laurie Jackson-Grusby | |||
J. Graeme Hodgson | |||
Jessica Dausman | |||
P2860 | cites work | Cancer Research | Q326097 |
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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality | Q28131773 | ||
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation | Q29618745 | ||
Hypomethylation distinguishes genes of some human cancers from their normal counterparts | Q29619217 | ||
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability | Q29620365 | ||
DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
DNA methylation in cancer: too much, but also too little | Q34770545 | ||
Reactivating the expression of methylation silenced genes in human cancer | Q34770617 | ||
Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus | Q34997520 | ||
The 5-methylcytosine content of DNA from human tumors | Q35689206 | ||
DNA methylation and genetic instability in colorectal cancer cells | Q36049856 | ||
Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues | Q37679466 | ||
DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair | Q39674490 | ||
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation | Q40834659 | ||
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis | Q41351086 | ||
5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result | Q41668069 | ||
Rearrangement of c-myc, pim-1 and Mlvi-1 and trisomy of chromosome 15 in MCF- and Moloney-MuLV-induced murine T-cell leukemias | Q43821654 | ||
Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation | Q45791002 | ||
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas | Q46369286 | ||
A short DNA methyltransferase isoform restores methylation in vivo. | Q50741462 | ||
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. | Q52201995 | ||
Suppression of intestinal neoplasia by DNA hypomethylation. | Q54613769 | ||
Analysis of early initiating event(s) in radiation-induced thymic lymphomagenesis. | Q54968940 | ||
The fundamental role of epigenetic events in cancer | Q56421597 | ||
Chromosomal Instability and Tumors Promoted by DNA Hypomethylation | Q63253103 | ||
X chromosome-linked transmission and expression of retroviral genomes microinjected into mouse zygotes | Q71233909 | ||
An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome | Q72228831 | ||
Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter | Q77328514 | ||
P433 | issue | 5618 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | chromosome abnormality | Q744962 |
DNA methylation | Q874745 | ||
P304 | page(s) | 489-92 | |
P577 | publication date | 2003-04-18 | |
P1433 | published in | Science | Q192864 |
P1476 | title | Induction of tumors in mice by genomic hypomethylation | |
Induction of Tumors in Mice by Genomic Hypomethylation | |||
P478 | volume | 300 |
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Q37082758 | Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon |
Q28678232 | Evolution of the cancer genome |
Q35111866 | Examination of whole blood DNA methylation as a potential risk marker for gastric cancer |
Q37080366 | Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer |
Q33743601 | Expression of t-DARPP mediates trastuzumab resistance in breast cancer cells |
Q34310997 | Field cancerization in mammary carcinogenesis - Implications for prevention and treatment of breast cancer |
Q36610921 | Foetal haemoglobin-blood cells (F-cells) as a feature of embryonic tumours (blastomas). |
Q33756188 | Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature. |
Q37088253 | Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations |
Q34478743 | Folate deficiency regulates expression of DNA polymerase β in response to oxidative stress |
Q36230469 | Frequent expression of MAGE1 tumor antigens in bronchial epithelium of smokers without lung cancer |
Q38472616 | Functional aspects of cytidine-guanosine dinucleotides and their locations in genes |
Q36930975 | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist |
Q33725090 | Functional interaction between co-expressed MAGE-A proteins |
Q34550628 | Future potential of the Human Epigenome Project |
Q34557714 | Gemifloxacin for the treatment of respiratory tract infections: in vitro susceptibility, pharmacokinetics and pharmacodynamics, clinical efficacy, and safety |
Q39821204 | Gene expression pattern and downregulation of DNA methyltransferase 1 using siRNA in porcine somatic cells |
Q40830535 | Genes and transposons are differentially methylated in plants, but not in mammals |
Q40047438 | Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma |
Q37070978 | Genetic signature for human risk assessment: lessons from trichloroethylene |
Q47177866 | Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival |
Q36497718 | Genetically engineered mouse models in cancer research |
Q37101724 | Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas |
Q41101024 | Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis |
Q37962581 | Genome-wide DNA methylation in human heart failure. |
Q28391482 | Genome-wide analysis in human colorectal cancer cells reveals ischemia-mediated expression of motility genes via DNA hypomethylation |
Q64956137 | Genome-wide hypomethylation of LINE-1 and Alu retroelements in cell-free DNA of blood is an epigenetic biomarker of human aging. |
Q35339140 | Genome-wide methylation profiling of the different stages of hepatitis B virus-related hepatocellular carcinoma development in plasma cell-free DNA reveals potential biomarkers for early detection and high-risk monitoring of hepatocellular carcinoma |
Q34122286 | Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. |
Q33242598 | Genomic alterations in ectopic and eutopic endometria of women with endometriosis |
Q38497589 | Genomic hypomethylation and CpG island hypermethylation in prostatic intraepithelial neoplasm |
Q34277089 | Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome |
Q38382440 | Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes |
Q36398297 | Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women |
Q36606069 | Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer |
Q90662533 | Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability |
Q37266816 | Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. |
Q53263685 | Global DNA hypomethylation coupled to cellular transformation and metastatic ability. |
Q34539547 | Global DNA hypomethylation in peripheral blood mononuclear cells as a biomarker of cancer risk |
Q48071382 | Global DNA hypomethylation is associated with the development and poor prognosis of tongue squamous cell carcinoma. |
Q64056571 | Global DNA methylation of peripheral blood leukocytes from dogs bearing multicentric non-Hodgkin lymphomas and healthy dogs: A comparative study |
Q34142428 | Global analysis of DNA methylation in early-stage liver fibrosis |
Q54287191 | Global demethylation in loss of imprinting subtype of Wilms tumor. |
Q33519525 | Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity |
Q37962571 | Global epigenetic profiling in bladder cancer. |
Q81007919 | Global increase in DNA methylation in patients with myelodysplastic syndrome |
Q90705372 | Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner |
Q24564106 | Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG |
Q35788928 | Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains |
Q38175087 | Harnessing the potential of epigenetic therapy to target solid tumors. |
Q92189808 | Helicase Lymphoid-Specific Enzyme Contributes to the Maintenance of Methylation of SST1 Pericentromeric Repeats That Are Frequently Demethylated in Colon Cancer and Associate with Genomic Damage |
Q38484630 | High resolution integrative analysis reveals widespread genetic and epigenetic changes after chronic in-vitro acid and bile exposure in Barrett's epithelium cells |
Q36423456 | High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer |
Q28513000 | Histone H3-K9 methyltransferase ESET is essential for early development |
Q37331641 | Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice |
Q40022345 | Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events |
Q42551273 | Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats |
Q28661652 | Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer |
Q27010001 | Human transposon tectonics |
Q40136348 | Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors). |
Q24305082 | Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer |
Q37446488 | Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis |
Q37961724 | Hypomethylation of repeated DNA sequences in cancer. |
Q39977133 | Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype |
Q91584734 | Identification of core differentially methylated genes in glioma |
Q34181789 | Identification of driver and passenger DNA methylation in cancer by epigenomic analysis |
Q28238147 | Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling |
Q38335531 | Identification of novel Myc target genes with a potential role in lymphomagenesis |
Q58101947 | Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study |
Q36386448 | Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes. |
Q55262096 | Impact of LINE-1 hypomethylation on the clinicopathological and molecular features of colorectal cancer patients. |
Q33996334 | Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components |
Q24306181 | Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 |
Q33914622 | In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation |
Q40448471 | Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. |
Q37812563 | Induced pluripotent cancer cells: progress and application |
Q26801711 | Induced pluripotent stem cell technology for dissecting the cancer epigenome |
Q35571293 | Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS. |
Q39709698 | Insights into the role of DNA methylation in disease through the use of mouse models |
Q36001915 | Insufficient DNA methylation affects healthy aging and promotes age-related health problems |
Q48375750 | Integrated Cellular and Plasma Proteomics of Contrasting B-cell Cancers Reveals Common, Unique and Systemic Signatures. |
Q35919690 | Integrated analysis of gene expression and DNA methylation changes induced by hepatocyte growth factor in human hepatocytes |
Q90705746 | Integrated genomic and methylation profile analysis to identify candidate tumor marker genes in patients with colorectal cancer |
Q28077579 | Integrating Epigenomics into the Understanding of Biomedical Insight |
Q36152246 | Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer |
Q37550690 | Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300. |
Q24658370 | Intra-individual change over time in DNA methylation with familial clustering |
Q38715367 | Intragenic DNA methylation prevents spurious transcription initiation |
Q36854908 | Intratumoral Heterogeneity of the Epigenome. |
Q58753393 | Ionizing Radiation and Human Health: Reviewing Models of Exposure and Mechanisms of Cellular Damage. An Epigenetic Perspective |
Q82799816 | Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo |
Q39233074 | Is DNA methylation the new guardian of the genome? |
Q39805891 | Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter |
Q35839338 | Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle. |
Q24799489 | L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas |
Q42908408 | LINE-1 activation and epigenetic silencing of suppressor genes in cancer: Causally related events? |
Q33886421 | LINE-1 hypomethylation during primary colon cancer progression |
Q33283510 | LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability |
Q37298707 | LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis |
Q54302136 | LINE-1 hypomethylation in noncancerous esophageal mucosae is associated with smoking history. |
Q37070832 | LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. |
Q33550560 | LINE-1 methylation difference between ameloblastoma and keratocystic odontogenic tumor |
Q41699788 | LINE-1 methylation level and patient prognosis in a database of 208 hepatocellular carcinomas |
Q39325725 | LINE-1 methylation level and prognosis in pancreas cancer: pyrosequencing technology and literature review |
Q34294473 | LINE-1 methylation status and its association with tetralogy of fallot in infants |
Q53345314 | Lack of correlation between DNA copy number and mRNA expression levels of c-myc in gamma-radiation-induced mouse thymic lymphomas by using quantitative real-time PCR. |
Q42960321 | Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate |
Q42186756 | Large-scale structure of genomic methylation patterns |
Q37079680 | Line region hypomethylation is associated with lifestyle and differs by human papillomavirus status in head and neck squamous cell carcinomas. |
Q36001900 | Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications |
Q44885739 | Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. |
Q53110472 | Loss of Dnmt3b accelerates MLL-AF9 leukemia progression. |
Q28589092 | Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis |
Q36064770 | Low-level environmental cadmium exposure is associated with DNA hypomethylation in Argentinean women |
Q28505283 | Lsh is involved in de novo methylation of DNA |
Q24297439 | MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents |
Q31150120 | MBD2 deficiency does not accelerate p53 mediated lymphomagenesis |
Q81672675 | MLL methylation is not likely a common mechanism for therapy-related AML |
Q24810367 | MSRE-PCR for analysis of gene-specific DNA methylation |
Q38747872 | Marked for death: targeting epigenetic changes in cancer |
Q92634851 | Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the Heart |
Q34611930 | Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype |
Q36671608 | MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status |
Q41968239 | Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer |
Q36803783 | Mechanisms of disease: methyl-binding domain proteins as potential therapeutic targets in cancer |
Q26861785 | Mechanisms of epigenetic regulation of leukemia onset and progression |
Q35945177 | Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma |
Q73456178 | Meddling with methylation |
Q33847875 | Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation |
Q37620965 | Methods for genome-wide analysis of DNA methylation in intestinal tumors |
Q33893167 | Methods in DNA methylation profiling |
Q35169101 | Methyl-binding domain protein 2-dependent proliferation and survival of breast cancer cells. |
Q36913739 | Methylated DNA and microRNA in body fluids as biomarkers for cancer detection. |
Q36891370 | Methylated DNA sequences for early cancer detection, molecular classification and chemotherapy response prediction |
Q64227434 | Methylation and ovarian cancer: Can DNA methylation be of diagnostic use? |
Q58695648 | Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women |
Q37040644 | Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer |
Q52895027 | Methylation of the Tumor Suppressor Genes HIC1 and RassF1A Clusters Independently From the Methylation of Polycomb Target Genes in Colon Cancer. |
Q40019764 | Methylation perturbations in retroelements within the genome of a Mus interspecific hybrid correlate with double minute chromosome formation. |
Q36076351 | Methylation profile of the promoter CpG islands of 14 "drug-resistance" genes in hepatocellular carcinoma |
Q36076356 | Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis |
Q24795636 | Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma |
Q47323579 | Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis |
Q80805160 | Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation |
Q35208036 | Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance |
Q37238372 | MiRNAs, epigenetics, and cancer |
Q38306947 | MicroRNA regulatory networks in idiopathic pulmonary fibrosis. |
Q30988873 | Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors |
Q33267829 | Mining methylation for early detection of common cancers |
Q31081839 | Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells |
Q28259737 | Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients |
Q34621450 | Modifiers of epigenetic reprogramming show paternal effects in the mouse. |
Q34790860 | Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study |
Q53612758 | Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation. |
Q60955182 | Molecular Mechanisms Underlying the Link between Diet and DNA Methylation |
Q38133084 | Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine |
Q37533620 | Molecular epigenetics and genetics in neuro-oncology |
Q37702543 | Molecular epigenetics in the management of ovarian cancer: are we investigating a rational clinical promise? |
Q38598168 | Monitoring Dynamics of DNA Methylation at Single-Cell Resolution during Development and Disease |
Q35124378 | Multiple sporadic colorectal cancers display a unique methylation phenotype |
Q36628683 | Multistep carcinogenesis of the colon in Apc(Min/+) mouse |
Q45866784 | Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells |
Q54574818 | Mutations galore in myeloproliferative neoplasms: would the real Spartacus please stand up? |
Q38150711 | Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer |
Q39069897 | Mutual regulation of microRNAs and DNA methylation in human cancers |
Q36848353 | Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer |
Q35699435 | Notes on the role of dynamic DNA methylation in mammalian development |
Q92890341 | Novel genes exhibiting DNA methylation alterations in Korean patients with chronic lymphocytic leukaemia: a methyl-CpG-binding domain sequencing study |
Q39800607 | Novel risk markers for gastric cancer screening: Present status and future prospects |
Q36617731 | Nuclear factor-kappab (NF-kappaB): an unsuspected major culprit in the pathogenesis of endometriosis that is still at large? |
Q53335948 | Oestrogen replacement therapy reduces total plasma homocysteine and enhances genomic DNA methylation in postmenopausal women. |
Q37629350 | On form and function: does chromatin packing regulate the cell cycle? |
Q64078658 | On the Complexity of Mechanisms and Consequences of Chromothripsis: An Update |
Q38020424 | On the role of retinoblastoma family proteins in the establishment and maintenance of the epigenetic landscape |
Q37634314 | Oncoviruses and Pathogenic MicroRNAs in Humans |
Q35867147 | One-Carbon Metabolism and Colorectal Cancer: Potential Mechanisms of Chemoprevention |
Q34016094 | Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis |
Q42107433 | Opposing roles of Dnmt1 in early- and late-stage murine prostate cancer |
Q33356247 | Optical mapping discerns genome wide DNA methylation profiles |
Q39627734 | Organomegaly and tumors in transgenic mice with targeted expression of HpaII methyltransferase in smooth muscle cells |
Q35998526 | Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation |
Q28554451 | Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation |
Q35620200 | Overlapping DNA methylation dynamics in mouse intestinal cell differentiation and early stages of malignant progression |
Q92351733 | Paradoxical association of TET loss of function with genome-wide DNA hypomethylation |
Q33415064 | Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity |
Q29614515 | Phenotypic plasticity and the epigenetics of human disease |
Q28384560 | Placental DNA hypomethylation in association with particulate air pollution in early life |
Q34955668 | Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore |
Q53212651 | Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1 - a hypothesis. |
Q37313424 | Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy |
Q26798810 | Potential of adipose-derived stem cells in muscular regenerative therapies |
Q33525767 | Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells |
Q36109663 | Predicting the effect of transcription therapy in hematologic malignancies |
Q34437941 | Prediction of methylated CpGs in DNA sequences using a support vector machine |
Q36211310 | Predictive properties of DNA methylation patterns in primary tumor samples for osteosarcoma relapse status |
Q64053408 | Prenatal epigenetics diets play protective roles against environmental pollution |
Q48674846 | Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT). |
Q36008593 | Procainamide is a specific inhibitor of DNA methyltransferase 1. |
Q35571288 | Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg |
Q55381984 | Prognostic value of LINE-1 methylation level in 321 patients with primary liver cancer including hepatocellular carcinoma and intrahepatic cholangiocarcinoma. |
Q38660226 | Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells |
Q83318087 | Promoter hypermethylation and global hypomethylation are independent epigenetic events in lymphoid leukemogenesis with opposing effects on clinical outcome |
Q36696681 | Promoter hypermethylation of MGMT, CDH1, RAR-beta and SYK tumour suppressor genes in granulosa cell tumours (GCTs) of ovarian origin |
Q44500993 | Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia |
Q46446472 | Promoter hypomethylation regulates CD133 expression in human gliomas |
Q38895486 | Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome. |
Q34182555 | Promoter-dependent mechanism leading to selective hypomethylation within the 5' region of gene MAGE-A1 in tumor cells |
Q36535688 | Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level |
Q33864173 | Proximity ligation in situ assay for monitoring the global DNA methylation in cells |
Q36189555 | RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation |
Q28239828 | RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity |
Q51848749 | RNA-directed epigenomic reprogramming: an emerging principle of a more targeted cancer therapy? |
Q36666502 | Radioadaptive response revisited. |
Q36090058 | Recent advances in molecular diagnosis and therapy of gastric cancer |
Q36941312 | Recreational and household physical activity at different time points and DNA global methylation. |
Q33217127 | Recruitment of DNA methyltransferase I to DNA repair sites |
Q27851629 | Recurrent DNMT3A mutations in patients with myelodysplastic syndromes |
Q41841980 | Recurrent chromosomal rearrangements implicate oncogenes contributing to T-cell lymphomagenesis in Lck-MyrAkt2 transgenic mice |
Q24536144 | Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis |
Q34384312 | Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. |
Q38879235 | Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation |
Q35020444 | Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice |
Q35153140 | Regulation and function of DNA methylation in plants and animals. |
Q37217178 | Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells |
Q37220124 | Regulation of pluripotency in male germline stem cells by Dmrt1. |
Q38911676 | Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer. |
Q92341929 | Regulation of transposable elements by DNA modifications |
Q41420061 | Relationship between LINE-1 hypomethylation and Helicobacter pylori infection in gastric mucosae |
Q39639045 | Repeat-element driven activation of proto-oncogenes in human malignancies |
Q37119615 | Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study |
Q42931458 | Replication stress, a source of epigenetic aberrations in cancer? |
Q34398115 | Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus |
Q37521263 | Reprogramming of a melanoma genome by nuclear transplantation |
Q28067369 | Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms |
Q26797512 | Response of transposable elements to environmental stressors |
Q24813212 | Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming |
Q61759292 | Retrotransposon-Driven Transcription and Cancer |
Q37129860 | Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer. |
Q38341003 | Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis |
Q38071897 | Review of the alterations in DNA methylation in esophageal squamous cell carcinoma |
Q38895216 | Rewiring the solid tumor epigenome for cancer therapy |
Q37810062 | Role of epigenetic therapy in myelodysplastic syndrome |
Q36459023 | Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression |
Q36155532 | Role of nuclear architecture in epigenetic alterations in cancer |
Q33697456 | Roles of retrotransposons in benign and malignant hematologic disease |
Q39056256 | Senescent cells harbour features of the cancer epigenome. |
Q35916111 | Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis. |
Q34687656 | Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk. |
Q28384337 | Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics |
Q33978878 | Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis |
Q50729608 | Sleeping Beauty transposition in the mouse genome is associated with changes in DNA methylation at the site of insertion. |
Q38383972 | Sodium bisulfite pyrosequencing revealed that developmental exposure to environmental contaminant mixtures does not affect DNA methylation of DNA repeats in Sprague-Dawley rats |
Q50504208 | Soma to germline inheritance of extrachromosomal genetic information via a LINE-1 reverse transcriptase-based mechanism. |
Q35694210 | Somatic DNA Hypomethylation in H. pylori-Associated High-Risk Gastritis and Gastric Cancer: Enhanced Somatic Hypomethylation Associates with Advanced Stage Cancer |
Q24657343 | Specific gene hypomethylation and cancer: new insights into coding region feature trends |
Q43152208 | Specific in vivo expression in type II pneumocytes of the Jaagsiekte sheep retrovirus long terminal repeat in transgenic mice |
Q37056726 | Specific inhibition of one DNMT1-including complex influences tumor initiation and progression. |
Q49956187 | Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma. |
Q45866358 | Stable gene expression occurs from a minority of integrated HIV-1-based vectors: transcriptional silencing is present in the majority |
Q37857056 | Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches. |
Q35749932 | Structure and function of eukaryotic DNA methyltransferases |
Q37829700 | Structure and function of mammalian DNA methyltransferases. |
Q47751941 | Study on the Interaction of the CpG Alternating DNA with CdTe Quantum Dots |
Q37301148 | Superoxide dismutase 1 knockdown induces oxidative stress and DNA methylation loss in the prostate. |
Q34563186 | Suppression of intestinal neoplasia by deletion of Dnmt3b |
Q42973524 | Suppressive effect of global DNA hypomethylation on gastric carcinogenesis |
Q38814744 | Sézary Syndrome: Clinical and Biological Aspects |
Q36197509 | TET proteins and 5-methylcytosine oxidation in hematological cancers |
Q89848688 | TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion |
Q34445845 | TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway |
Q90429907 | Targeting DNA Hypomethylation in Malignancy by Epigenetic Therapies |
Q36150848 | Targeting epigenetic regulatory mechanisms in cancer chemoprevention |
Q33890546 | Targeting the epigenome in malignant pleural mesothelioma |
Q28511594 | Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice |
Q35025083 | Testing gene function early in the B cell lineage in mb1-cre mice |
Q36673761 | The 'de novo' DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium. |
Q34772160 | The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies |
Q37029584 | The Aging Epigenome |
Q35702082 | The Association of LINE-1 Hypomethylation with Age and Centromere Positive Micronuclei in Human Lymphocytes |
Q42364239 | The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks |
Q33750243 | The DNA methylome of human peripheral blood mononuclear cells |
Q36063358 | The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation |
Q35571262 | The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease |
Q58789495 | The Methylation Status of the Epigenome: Its Emerging Role in the Regulation of Tumor Angiogenesis and Tumor Growth, and Potential for Drug Targeting |
Q28507079 | The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin |
Q41923596 | The REMOTE-control system: a system for reversible and tunable control of endogenous gene expression in mice |
Q64108233 | The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome |
Q40262798 | The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation |
Q44737509 | The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine |
Q36109310 | The altered DNA methylation pattern and its implications in liver cancer |
Q37911496 | The application of delivery systems for DNA methyltransferase inhibitors |
Q35207554 | The application of functional genomics to Alzheimer's disease |
Q52902095 | The enemy within: an epigenetic role of retrotransposons in cancer initiation. |
Q39021700 | The epigenetic landscape of renal cancer |
Q29617486 | The epigenetic progenitor origin of human cancer |
Q34310378 | The epigenetics of epithelial-mesenchymal plasticity in cancer |
Q36252000 | The epigenome as a molecular marker and target |
Q29617273 | The history of cancer epigenetics |
Q36286073 | The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases |
Q38063931 | The methylation landscape of tumour metastasis |
Q45792913 | The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance |
Q33698033 | The new field of epigenomics: implications for cancer and other common disease research. |
Q33782233 | The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer |
Q37903980 | The potential role of epigenetic responses to diet in ageing |
Q38673415 | The potential role of retroviruses in autoimmunity |
Q44294975 | The promise of epigenetic therapies in treatment of idiopathic pulmonary fibrosis |
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