| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/SJ.ONC.1207175 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/sj.onc.1207175 |
| P698 | PubMed publication ID | 14737108 |
| P5875 | ResearchGate publication ID | 8908537 |
| P50 | author | Manel Esteller | Q3816008 |
| Manuel Serrano | Q42491729 | ||
| P2093 | author name string | Mario F Fraga | |
| Gonzalo González de Buitrago | |||
| María Nieto | |||
| Enrique Samper | |||
| P2860 | cites work | Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 |
| p53 mutations in human cancers | Q28302973 | ||
| p53-dependent apoptosis modulates the cytotoxicity of anticancer agents | Q29615031 | ||
| Tumor spectrum analysis in p53-mutant mice | Q29617436 | ||
| Induction of Tumors in Mice by Genomic Hypomethylation | Q29618551 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| Radiation-induced cell cycle arrest compromised by p21 deficiency | Q29620237 | ||
| Clinical implications of p53: effect on prognosis, tumor progression and chemotherapy response | Q33547823 | ||
| A genome-wide survey of RAS transformation targets | Q33888438 | ||
| p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes | Q33963455 | ||
| DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis | Q34132208 | ||
| Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. | Q34204305 | ||
| If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells | Q34625589 | ||
| DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
| 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy | Q34770609 | ||
| The role of p53 in determining sensitivity to radiotherapy | Q35058584 | ||
| Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation | Q35939534 | ||
| p53 mutations increase resistance to ionizing radiation | Q36373753 | ||
| Wild-type p53 is a cell cycle checkpoint determinant following irradiation | Q37152060 | ||
| Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos | Q39645050 | ||
| The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes | Q40399652 | ||
| Role of p53 in leukemogenesis of chronic myeloid leukemia | Q40407098 | ||
| Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53. | Q40679903 | ||
| Induction of senescence by oncogenic Ras. | Q40800050 | ||
| DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts | Q40815312 | ||
| Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation | Q40834659 | ||
| Primary mouse fibroblasts deficient for c-Fos, p53 or for both proteins are hypersensitive to UV light and alkylating agent-induced chromosomal breakage and apoptosis | Q40838820 | ||
| Cellular differentiation, cytidine analogs and DNA methylation | Q42242732 | ||
| Nuclear Apaf-1 and cytochrome c redistribution following stress-induced apoptosis | Q42813889 | ||
| Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine. | Q43548377 | ||
| High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues | Q44102949 | ||
| Inhibition of DNA methylation and reactivation of silenced genes by zebularine | Q44346779 | ||
| P53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts. | Q44953358 | ||
| Predicting response to cancer chemotherapy: the role of p53. | Q45887109 | ||
| p53 loss and point mutations are associated with suppression of apoptosis and progression of CML into myeloid blastic crisis. | Q53440352 | ||
| Role of the INK4a locus in tumor suppression and cell mortality. | Q53455197 | ||
| Delayed DNA damage associated with mitotic catastrophe following X-irradiation of HeLa S3 cells. | Q55067810 | ||
| Single-step, multiple retroviral transduction of human T cells | Q57351531 | ||
| p19ARF links the tumour suppressor p53 to Ras | Q57562848 | ||
| Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity | Q58487871 | ||
| Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response | Q59139048 | ||
| Chromosomal Instability and Tumors Promoted by DNA Hypomethylation | Q63253103 | ||
| Mutations of the p53 gene in myelodysplastic syndrome and overt leukemia | Q70874175 | ||
| E2F-1 functions in mice to promote apoptosis and suppress proliferation | Q71129257 | ||
| S-adenosyl-L-homocysteine: a non-cytotoxic hypomethylating agent | Q71634269 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 735-743 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine | |
| P478 | volume | 23 |
| Q40479015 | 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia. |
| Q40491235 | 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms |
| Q38696769 | 5-aza-2',2'-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of Cancer |
| Q33901844 | A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation |
| Q36623335 | Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos |
| Q84596559 | Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells |
| Q39672023 | Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance with IFN-Stimulated Gene Expression |
| Q39100888 | Combined treatment with low concentrations of decitabine and SAHA causes cell death in leukemic cell lines but not in normal peripheral blood lymphocytes |
| Q38778658 | DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins. |
| Q40054309 | DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. |
| Q40453633 | De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. |
| Q38971726 | Decitabine induces delayed reactive oxygen species (ROS) accumulation in leukemia cells and induces the expression of ROS generating enzymes |
| Q37162642 | Decreased expression of connective tissue growth factor in non-small cell lung cancer is associated with clinicopathological variables and can be restored by epigenetic modifiers. |
| Q39974237 | Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin |
| Q37789778 | Epigenetic mechanisms in senescence, immortalisation and cancer |
| Q45215124 | Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway |
| Q37637537 | Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer |
| Q92502266 | Opposing effects of acute versus chronic inhibition of p53 on decitabine's efficacy in myeloid neoplasms |
| Q47121630 | P53 at the start of the 21st century: lessons from elephants. |
| Q37313424 | Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy |
| Q47833426 | Putting p53 in Context |
| Q39011822 | SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome |
| Q38955075 | Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells |
| Q40262211 | Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma |
| Q26745731 | Targeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trials |
| Q39566623 | The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells |
| Q38879761 | The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation |
| Q38618938 | The cardiac glycoside convallatoxin inhibits the growth of colorectal cancer cells in a p53-independent manner. |
| Q37186709 | The epigenetics of adult (somatic) stem cells |
| Q47101729 | The interplay between epigenetic changes and the p53 protein in stem cells. |
| Q37702494 | The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA. |
| Q35795835 | Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design |
| Q43249171 | p53 and DNA methylation suppress the TRAIN to cell death |
| Q36512094 | p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs |
| Q94671691 | p53: 800 million years of evolution and 40 years of discovery |
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