Cellular differentiation, cytidine analogs and DNA methylation

scientific article published on May 1, 1980

Cellular differentiation, cytidine analogs and DNA methylation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0092-8674(80)90237-8
P953full work available at URLhttps://api.elsevier.com/content/article/PII:0092867480902378?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:0092867480902378?httpAccept=text/xml
P698PubMed publication ID6156004

P2093author name stringP. A. Jones
S. M. Taylor
P2860cites workX inactivation, differentiation, and DNA methylationQ33999850
Biological effects of 5-azacytidine in eukaryotesQ34202821
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of divisionQ34207595
Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidineQ34418477
Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell linesQ37339666
Drug effects on nucleic acid modification. I. A specific effect of 5-azacytidine on mammalian transfer RNA methylation invivoQ39379573
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidineQ39436052
Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatmentQ39438664
Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosidesQ39548154
The effect of 5-azacytidine on E.coli DNA methylaseQ39571616
Direct detection of methylated cytosine in DNA by use of the restriction enzyme MsplQ40240812
Correlation between Hypomethylation of DNA and Expression of Globin Genes in Friend Erythroleukemia CellsQ40511566
DNA methylation at a CCGG sequence in the large intron of the rabbit beta-globin gene: tissue-specific variationsQ40576746
Methylation of Mouse Liver DNA Studied by Means of the Restriction Enzymes Msp I and Hpa IIQ41466255
Specific DNA methylation sites in the vicinity of the chicken beta-globin genesQ41700571
Use of restriction enzymes to study eukaryotic DNA methylation: II. The symmetry of methylated sites supports semi-conservative copying of the methylation pattern.Q43769987
Mechanism of action of rat liver DNA methylase. I. Interaction with double-stranded methyl-acceptor DNA.Q47753057
Use of restriction enzymes to study eukaryotic DNA methylationQ60895212
A procedure for the isolation of deoxyribonucleic acid from micro-organismsQ61773073
Methylated and unmethylated DNA compartments in the sea urchin genomeQ64441645
Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidineQ70024413
Cytotoxicity and mode of action of 5-azacytidine on L1210 leukemiaQ71611069
Measurement of S-adenosyl-l-methionine levels by SP sephadex chromatographyQ77375287
Distribution of 5-methylcytosine in pyrimidine sequences of deoxyribonucleic acidsQ79379126
Destructive processing of the 45-S ribosomal precursor in the presence of 5-azacytidineQ93737138
Chemistry. How are alkynes scrambled?Q95780598
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDNA methylationQ874745
P304page(s)85-93
P577publication date1980-05-01
P1433published inCellQ655814
P1476titleCellular differentiation, cytidine analogs and DNA methylation
P478volume20

Reverse relations

cites work (P2860)
Q3044589610T1/2 cells: an in vitro model for molecular genetic analysis of mesodermal determination and differentiation
Q4759431115N-enriched 5-fluorocytosine as a probe for examining unusual DNA structures
Q368611232'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Q423905032'-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation
Q363414882′-Deoxyriboguanylurea, the primary breakdown product of 5-aza-2′-deoxyribocytidine, is a mutagen, an epimutagen, an inhibitor of DNA methyltransferases and an inducer of 5-azacytidine-type fragile sites
Q413683893-Deazauridine (NSC 126849): an interesting modulator of biochemical response
Q451176725-AZA-2′-deoxycytidine therapy in patients with acute leukemia inhibits DNA methylation
Q439561865-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse
Q360898875-Aza-2′-deoxycytidine Induced Growth Inhibition of Leukemia Cells through Modulating Endogenous Cholesterol Biosynthesis
Q716030665-Azacytidine (NSC 102816) in refractory germ cell tumors. A phase II trial of the Eastern Cooperative Oncology Group
Q726823115-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia
Q347706095-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
Q360291365-Azacytidine and 5-aza-2'-deoxycytidine behave as different antineoplastic agents in B16 melanoma
Q435988585-Azacytidine induced inhibition of mitogenic response by agents that activate or augment activation of human peripheral blood T lymphocytes
Q727250755-Azacytidine induced myogenesis in a differentiation defective cell line
Q737404565-Azacytidine induces toxicity in PC12 cells by apoptosis
Q363749785-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation
Q727224215-Azacytidine induction of thymidine kinase in a spontaneously enzyme-deficient murine tumor line
Q339394865-Azacytidine is able to induce the conversion of teratocarcinoma-derived mesenchymal cells into epithelia cells
Q367004385-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression
Q368294705-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael
Q401097745-Azacytidine, DNA Methylation, and Differentiation
Q535657195-Azacytidine-Induced Reactivation of a Herpes Simplex Thymidine Kinase Gene
Q416552285-Azacytidine-induced demethyelation of DNA to senescent level does not block proliferation of human fibroblasts
Q620596225-Azacytidine-induced re-expression of alleles on the inactive X chromosome in a hybrid mouse cell line
Q585557985-Azacytidine: A Promoter of Epigenetic Changes in the Quest to Improve Plant Somatic Embryogenesis
Q360482175-Methylcytosine depletion during tumour development: An extension of the miscoding concept
Q282627885-Methylcytosine, Gene Regulation, and Cancer
Q406515975-aza-2'-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells
Q438864495-aza-C-induced changes in the time of replication of the X chromosomes of Microtus agrestis are followed by non-random reversion to a late pattern of replication
Q362502015-azacytidine and decitabine monotherapies of myelodysplastic disorders
Q352323605-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia
Q339578405-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells
Q727474975-azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: Evidence for regulatory genes controlling determination
Q380148985-azacytosine compounds in medicinal chemistry: current stage and future perspectives
Q371711586-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo
Q28831002A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
Q41090697A Novel Aortic Smooth Muscle Cell Line Obtained from p53 Knock Out Mice Expresses Several Differentiation Characteristics
Q26743743A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers
Q37696774A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells
Q21144289A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans
Q24614467A decade of exploring the cancer epigenome — biological and translational implications
Q36219130A growth factor-repressible gene associated with protein kinase C-mediated inhibition of adipocyte differentiation
Q36159688A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase
Q35794439A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy
Q28333475A new insight into the histogenesis of 'mesodermomas'--malignant mesotheliomas
Q50020673A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from TACL consortium
Q35130668A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine, administered with tetrahydrouridine
Q36682845A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome.
Q35212344A pilot study of subcutaneous decitabine in β-thalassemia intermedia
Q67487494A procedure for selecting mammalian cells with an impairment in oxidative phosphorylation
Q35265834A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome
Q36689145A prospective, multicenter, observational study of long-term decitabine treatment in patients with myelodysplastic syndrome
Q34447578ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth
Q28272449AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity
Q38171316Aberrant DNA methylation in human cancers
Q35075702Aberrant methylation of gene associated CpG sites occurs in borderline personality disorder
Q40584383Aberrant methylation of integrin alpha4 gene in human gastric cancer cells.
Q36223014Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells
Q41553016Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets
Q36008890Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus.
Q36263881Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate
Q72710915Activation of intracistemal a particles by 5-azacytidine in mouse Ki-BALB cell line
Q45805408Activation of the epstein-barr virus genome by 5-aza-cytidine in latently infected human lymphoid lines
Q41282882Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels
Q36211517Adipocyte conversion of CHEF cells in serum-free medium
Q36154766Advances in Genome-Wide DNA Methylation Analysis
Q34312351Advances in treating acute myeloid leukemia
Q38203863Age-related changes in DNA methylation: do they represent continued developmental changes?
Q37410585Aging and epigenetic drift: a vicious cycle
Q71068431Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis
Q40110746Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis
Q28394199Alzheimer’s Disease and Environmental Exposure to Lead: The Epidemiologic Evidence and Potential Role of Epigenetics
Q35310832Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine
Q57093404An epigenetic mechanism for cavefish eye degeneration
Q28762983Analysis of tissue-specific differentially methylated regions (TDMs) in humans
Q67535242Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes
Q36345656Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma.
Q25255934Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines
Q34031951Application of Epigenome‐Modifying Small Molecules in Induced Pluripotent Stem Cells
Q53552519Arabinosylcytosine Induces Fetal Hemoglobin in Baboons by Perturbing Erythroid Cell Differentiation Kinetics
Q36047040Associations of ChREBP and Global DNA Methylation with Genetic and Environmental Factors in Chinese Healthy Adults
Q42778979At the tipping point for epigenetic therapies in cancer
Q35048054Augmenting antitumor immune responses with epigenetic modifying agents
Q38838783Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives
Q37645183Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines
Q68973748Azacytidine-induced reactivation of adenosine deaminase in a murine cytotoxic T cell line
Q35916793Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies
Q40417006Binding of the EcoRII methylase to azacytosine-containing DNA.
Q38328039Binding of the EcoRII methyltransferase to 5-fluorocytosine-containing DNA. Isolation of a bound peptide
Q46401677Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice
Q41403304Biological and molecular studies on Syrian hamster intracisternal R-type particles
Q28307510Biological implications of the mechanism of action of human DNA (cytosine-5)methyltransferase
Q37198930Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells
Q37192659Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults
Q35213136Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications
Q37248365Breast cancer epigenetics: normal human mammary epithelial cells as a model system
Q36895736Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells
Q34690069Butyrate selectively activates the metallothionein gene in teratocarcinoma cells and induces hypersensitivity to metal induction
Q33425892CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells
Q39697060Can cancer chemotherapy enhance the malignant behaviour of tumours?
Q37368971Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective
Q35844494Cancer epigenetics: above and beyond
Q35348043Cancer epigenetics: linking basic biology to clinical medicine.
Q36293366Carcinogen- and radiation-transformed C3H 10T1/2 cells contain RNAs homologous to the long terminal repeat sequence of a murine leukemia virus
Q36466174Carcinogenicity and haemoglobin synthesis induction by cytidine analogues
Q54485278Cell cycle effects and cellular pharmacology of 5-AZA-2?-deoxycytidine
Q42824627Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements
Q36282892Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine
Q33253085Cell kinetic disturbances induced by treatment of human diploid fibroblasts with 5-azacytidine indicate a major role for DNA methylation in the regulation of the chromosome cycle.
Q72086896Cell-cycle dependent micronucleus formation and mitotic disturbances induced by 5-azacytidine in mammalian cells
Q36970469Cellular Moloney Murine Sarcoma (c-mos) Sequences Are Hypermethylated and Transcriptionally Silent in Normal and Transformed Rodent Cells
Q46174159Cellular metabolism of 1-beta-D-arabinofuranosyl-5-azacytosine and incorporation into DNA and RNA of human lymphoid CEM/0 and CEM/dCk(-) cells
Q46008975Cellular metabolism of 5,6-dihydro-5-azacytidine and its incorporation into DNA and RNA of human lymphoid cells CEM/O and CEM/dCk(-).
Q53565632Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine
Q96428227Characterization of stress response involved in chicken myopathy
Q33687040Characterization of the promoter region of the mouse Xist gene
Q40422315Chemical synthesis of 2′-deoxyoligonucleotides containing 5-fluoro-2′-deoxycytidine
Q40456209Chemical synthesis of 5-azacytidlne nucleotides and preparation of tRNAs containing 5-azacytidine in its 3′-terminus
Q24806085Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites
Q54369162Chemotherapy of L1210 and L1210/ARA-C leukemia with 5-aza-2'-deoxycytidine and 3-deazauridine
Q59086364Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation
Q37073231Chromatin, cancer and drug therapies
Q38053238Clinical Results With the DNA Hypomethylating Agent 5-Aza-2′-Deoxycytidine (Decitabine) in Patients With Myelodysplastic Syndromes: An Update
Q40109504Cloning of Contractile Protein Genes
Q54503106Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII
Q72611266Clustering of multiple transgene integrations in highly-unstable Ascobolus immersus transformants
Q35838583Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs.
Q38926364Combined analysis of DNA methylation and cell cycle in cancer cells
Q34981266Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors
Q67675052Comparison of antineoplastic activity of cytosine arabinoside and 5-aza-2′-deoxycytidine against human leukemic cells of different phenotype
Q36466835Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia
Q54664359Comparison of transformation efficiency of human active and inactive X-chromosomal DNA.
Q35545116Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells
Q91582166Contribution of promoter DNA sequence to heterochromatin formation velocity and memory of gene repression in mouse embryo fibroblasts
Q72687822Controlling the fetal globin switch in man
Q42480726Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus.
Q40111142Conversion of iris epithelial cells as a model of differentiation control
Q39695383Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements
Q72721309Coreactivation of four inactive X genes in a hamster � human hybrid and persistence of late replication of reactivated X chromosome
Q37576837Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
Q39139055CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors
Q28131800CpG-rich islands and the function of DNA methylation
Q71557465Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes
Q40164069Cytoplasmic modification of nuclear gene expression
Q35692564Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.
Q72664566Cytotoxic effects of butyrate and other ‘differentiation inducers’ on immature lymphoid cells
Q67536246Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system
Q37374120DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
Q38979940DNA Hypomethylating Drugs in Cancer Therapy
Q57143629DNA Methylation Detection Using Resonance and Nanobowtie-Antenna-Enhanced Raman Spectroscopy
Q34174778DNA Methylation and Demethylation in Mammals
Q28263722DNA Methylation and Gene Function
Q40109779DNA Methylation in Friend Erythroleukemia Cells: The Effects of Chemically Induced Differentiation and of Treatment with Inhibitors of DNA Methylation
Q58860107DNA Methyltransferase Inhibitors
Q39003558DNA Methyltransferase Inhibitors: Development and Applications.
Q36654458DNA and histone methylation in gastric carcinogenesis
Q24792540DNA and the chromosome - varied targets for chemotherapy
Q34972245DNA demethylating antineoplastic strategies: a comparative point of view
Q27011914DNA demethylation and invasive cancer: implications for therapeutics
Q35200759DNA demethylation induced by 5-azacytidine does not affect fragile X expression
Q37846279DNA hypermethylation as a chemotherapy target
Q40527734DNA hypermethylation in gastric cancer
Q39923092DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity.
Q34788574DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia.
Q43735309DNA hypomethylation of karyoplasts for bovine nuclear transplantation.
Q39208639DNA methylation aberrancies as a guide for surveillance and treatment of human cancers
Q36925095DNA methylation affecting the expression of murine leukemia proviruses
Q33875819DNA methylation and cancer
Q33632335DNA methylation and chromatin modification.
Q36581357DNA methylation and development
Q30498513DNA methylation and differentiation
Q36944389DNA methylation and expression of HLA-DR alpha
Q37057353DNA methylation and gene expression
Q40124163DNA methylation and its possible biological roles
Q36951024DNA methylation and systemic lupus erythematosus
Q41730013DNA methylation as a target for drug design
Q58390463DNA methylation as a transcriptional regulator of the immune system
Q33857557DNA methylation changes in a human cell model of breast cancer progression
Q44970194DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium
Q51256105DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells
Q37723600DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay
Q35149910DNA methylation dynamics in muscle development and disease
Q36948603DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells
Q36803766DNA methylation in breast and colorectal cancers
Q40196814DNA methylation in eukaryotic cells.
Q35594048DNA methylation in haematological malignancies: the role of decitabine
Q26852141DNA methylation in mammals
Q42825517DNA methylation in mouse cells in culture as measured by restriction enzymes
Q100515583DNA methylation methods: global DNA methylation and methylomic analyses
Q86738541DNA methylation of embryogenic carrot cell cultures and its variations as caused by mutation, differentiation, hormones and hypomethylating drugs
Q37818614DNA methylation of genes in adipose tissue.
Q36268174DNA methylation pattern is determined by the intracellular level of the methylase
Q22065780DNA methylation patterns and epigenetic memory
Q37188534DNA methylation patterns in lung carcinomas
Q33669206DNA methylation prevents transfection of genes for specific surface antigens
Q41333669DNA methylation: biology and significance
Q36986433DNA methylation: its role in cancer development and therapy
Q88511739DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine
Q36910685DNA methyltransferase induced by frog virus 3
Q39671498DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer
Q38040883DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences
Q40109029DNA modification, differentiation, and transformation
Q33615323DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.
Q36032155DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity
Q39560130DNMT3B gene amplification predicts resistance to DNA demethylating drugs
Q40453633De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine.
Q36302181De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells
Q79373089Decitabine
Q58603918Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
Q36118290Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing
Q92705272Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice
Q33392205Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience
Q37568244Decitabine in the treatment of acute myeloid leukemia in elderly patients
Q34088403Decitabine in the treatment of myelodysplastic syndromes.
Q40997606Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus
Q39319043Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation
Q36284232Decitabine: a historical review of the development of an epigenetic drug
Q38314204Decitabine: a promising epi-immunotherapeutic agent in solid tumors
Q40352317Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome
Q35643289Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines.
Q30450911Delta-crystallin genes become hypomethylated in postmitotic lens cells during chicken development
Q33678040Demethylating Agents in the Treatment of Cancer
Q34847863Demethylating agents in myeloid malignancies
Q45847197Demethylation by 5-azacytidine results in the expression of hepatitis B virus surface antigen in transgenic mice
Q36848582Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression
Q44590135Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres
Q53549693Demethylation of the type I procollagen genes in transformed fibroblasts treated with 5-azacytidine
Q43182059Dependence of transcriptional repression on CpG methylation density
Q77225234Derepression of genes on the human inactive X chromosome: Evidence for differences in locus-specific rates of derepression and rates of transfer of active and inactive genes after DNA-mediated transformation
Q59087665Derivation of macrophage-like lines from the pre-B lymphoma ABLS 8.1 using 5-azacytidine
Q44023657Determination of purine and pyrimidine bases in DNA by micellar electrokinetic capillary chromatography with electrochemical detection
Q52191554Development-dependent inheritance of 5-azacytidine-induced epimutations in triticale: analysis of rDNA expression patterns
Q38630962Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers
Q42243662Developmental activation of the H-2K gene is correlated with an increase in DNA methylation
Q50014666Dietary Modulation of the Epigenome
Q37163592Differential CpG island methylation of murine adenine nucleotide translocase genes
Q36764112Differential activation of the hprt gene on the inactive X chromosome in primary and transformed Chinese hamster cells
Q35365141Differential activity of DNA methyltransferase in the life cycle of Chlamydomonas reinhardi
Q41279630Differential gene activity visualized on sister chromatids after replication in the presence of 5-azacytidine
Q45866909Differential inhibition of sister chromatid condensation induced by 5-azadeoxycytidine in human chromosomes
Q36920588Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance
Q37336912Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains
Q36323576Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate
Q36260958Differentiation of myoblast cell lines and biological methylation: 3-deazaadenosine stimulates formation of multinucleated myofibers
Q41201437Differentiation of smooth muscle phenotypes in mouse mesangial cells
Q33409795Differentiation therapy of leukemia: 3 decades of development
Q36523796Digging deep into "dirty" drugs - modulation of the methylation machinery
Q57831457Distinct modes of DNA accessibility in plant chromatin
Q40105518Dna Methylation in Eukaryote
Q37371537Dnmt1 regulates the myogenic lineage specification of muscle stem cells
Q24810666Down-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter region
Q40040187Duck hepatitis B virus infection of Muscovy duck hepatocytes and nature of virus resistance in vivo
Q36604669Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage
Q38222879Early environment influences later performance in fishes
Q37372837Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
Q36397293Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2.
Q39552288Effect of 5-azacytidine on DNA methylation and on the enzymes of de novo pyrimidine biosynthesis in Bacillus subtilis Marburg strain
Q72741862Effect of 5-azacytidine on deoxyribonucleic acid methylation in Escherichia coli K12
Q34410486Effect of 5-azacytidine on in vitro biofilm formation of Streptococcus pneumoniae
Q40975583Effect of CpG methylation on expression of the mouse imprinted gene Mest.
Q41651195Effect of Dibutyryl Cyclic Adenosine 3',5'-Monophosphate on Morphological Features and Biological Markers of Human Salivary Myoepithelial Cell Line in Culture
Q39974567Effect of a new pyrimidine analog on Bacillus subtilis growth
Q36847124Effect of cellular determination on oncogenic transformation by chemicals and oncogenes
Q43860783Effect of cytidine analogs on cell growth and differentiation on a human neuroblastoma line
Q36282015Effect of methylation on expression of microinjected genes
Q40490079Effect of several inhibitors of enzymatic DNA methylation on thein vivomethylation of different classes of DNA sequences in a cultured human cell line
Q35032927Effect of substratum and retinoids upon the mucosecretory differentiation of airway epithelial cells in vitro
Q47936349Effects of 5-Azacytidine and Butyrate on Differentiation and Apoptosis of Hepatic Cancer Cell Lines
Q36943333Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells
Q72740318Effects of 5-azacytosine in DNA on enzymic uracil excision
Q35824357Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells
Q36762963Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.
Q39639196Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors
Q35750354Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine
Q37381606Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
Q40006128Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells
Q28488736Embryonic carcinoma cells show specific dielectric resistance profiles during induced differentiation
Q37962013Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers
Q36347785Endogenous retrovirus expression in stimulated murine lymphocytes. Identification of a new locus controlling mitogen induction of a defective virus
Q36140986Engineering lymphocyte subsets: tools, trials and tribulations
Q46886114Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs
Q61642710Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine
Q64915302Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations.
Q37700733Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry
Q44441820Epigenetic Characteristics and Development of Embryos Cloned from Donor Cells Treated by Trichostatin A or 5-aza-2′-deoxycytidine1
Q64998142Epigenetic Crosstalk between the Tumor Microenvironment and Ovarian Cancer Cells: A Therapeutic Road Less Traveled.
Q38837858Epigenetic Determinants of Cancer
Q37941536Epigenetic Drug Discovery: Targeting DNA Methyltransferases
Q89996538Epigenetic Modification and Differentiation Induction of Malignant Glioma Cells by Oligo-Fucoidan
Q64076648Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity
Q38969422Epigenetic Regulation of the Thermogenic Adipose Program
Q55433291Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia.
Q38041528Epigenetic Targeting Therapies to Overcome Chemotherapy Resistance
Q88669597Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion
Q52674783Epigenetic Therapeutics and Their Impact in Immunotherapy of Lung Cancer.
Q28072370Epigenetic Therapeutics: A New Weapon in the War Against Cancer
Q33863567Epigenetic Therapies in MDS and AML
Q38537883Epigenetic Therapy in Acute Myeloid Leukemia: Current and Future Directions
Q36641966Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells
Q38051195Epigenetic aspects of MDS and its molecular targeted therapy
Q37969665Epigenetic cancer therapy: rationales, targets and drugs
Q34385658Epigenetic changes in prostate cancer: implication for diagnosis and treatment
Q33767309Epigenetic changes in the myelodysplastic syndrome.
Q42409031Epigenetic control of epithelial-mesenchymal-transition in human cancer
Q37854164Epigenetic control of gene regulation in plants
Q55477773Epigenetic control of programmed cell death: inhibition by 5-azacytidine of 1,25-dihydroxyvitamin D3-induced programmed cell death in C6.9 glioma cells
Q33740709Epigenetic deregulation in pediatric acute lymphoblastic leukemia.
Q28305955Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer
Q38986705Epigenetic drug discovery: breaking through the immune barrier
Q26864455Epigenetic epidemiology: promises for public health research
Q50132467Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance
Q36310399Epigenetic mechanisms and gene networks in the nervous system.
Q30489308Epigenetic mechanisms and the transgenerational effects of maternal care
Q37789778Epigenetic mechanisms in senescence, immortalisation and cancer
Q37412329Epigenetic mechanisms of regulation of Foxp3 expression
Q37193994Epigenetic modifications of embryonic stem cells: current trends and relevance in developing regenerative medicine
Q45976173Epigenetic modifiers: basic understanding and clinical development.
Q37962586Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance
Q38358635Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells
Q36266756Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo
Q38844664Epigenetic regulation in gallbladder cancer: Promoter methylation profiling as emergent novel biomarkers
Q37850456Epigenetic regulation in myelodysplastic syndromes: implications for therapy
Q39045550Epigenetic regulation of immune checkpoints: another target for cancer immunotherapy?
Q48684687Epigenetic regulation of neural N-glycomics
Q34498966Epigenetic regulation of pluripotency and differentiation
Q36001910Epigenetic regulation of prostate cancer
Q90208950Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to viral directed immunotherapy
Q90010176Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma
Q37567572Epigenetic therapeutics in autoimmune disease
Q33621141Epigenetic therapies for chemoresensitization of epithelial ovarian cancer.
Q89652991Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitors
Q38459836Epigenetic therapy for solid tumors: from bench science to clinical trials
Q26745709Epigenetic therapy in gastrointestinal cancer: the right combination
Q91361596Epigenetic therapy in immune-oncology
Q38121995Epigenetic therapy in non-small-cell lung cancer: targeting DNA methyltransferases and histone deacetylases.
Q38332497Epigenetic therapy of cancer stem and progenitor cells by targeting DNA methylation machineries
Q36399557Epigenetic therapy of cancer: past, present and future
Q36429559Epigenetic therapy with decitabine for myelodysplasia and leukemia
Q37964702Epigenetic-based therapies in cancer: progress to date
Q44555512Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines
Q36449057Epigenetics as a Therapeutic Target in Breast Cancer
Q29547437Epigenetics in human disease and prospects for epigenetic therapy
Q26749113Epigenetics in non-small cell lung cancer: from basics to therapeutics
Q24812104Epigenetics of cervical cancer. An overview and therapeutic perspectives
Q36505767Epigenetics of lung cancer
Q37785109Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics
Q54765415Epigenetics, fragile X syndrome and transcriptional therapy.
Q38770916Epigenetics: A primer for clinicians
Q37992592Epigenetics: Concepts and relevance to IBD pathogenesis
Q35118477Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor Suppressor Genes
Q37078784Epigenomics and breast cancer
Q35636575Epigenomics and ovarian carcinoma.
Q37824255Epigenomics in cancer management
Q33938743Epimutation of repeated genes in Ascobolus immersus
Q28475641Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome
Q38584326Eukaryotic DNA methylation
Q34768789Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies
Q28236365Evolutionary conservation of fragile sites induced by 5-azacytidine and 5-azadeoxycytidine in man, gorilla, and chimpanzee
Q35563121Ex vivo expansion of human mobilized peripheral blood stem cells using epigenetic modifiers
Q57205784Expression and Hypomethylation of α-Fetoprotein Gene in Unicentric and Multicentric Human Hepatocellular Carcinomas
Q48944684Expression and methylation of the mouse alpha-fetoprotein gene in embryonic, adult, and neoplastic tissues
Q53223510Expression and mutational analysis of Cip/Kip family in early glottic cancer
Q28748604Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors
Q35459761Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation
Q37636759Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells.
Q36316583Expression of transferred thymidine kinase genes is controlled by methylation
Q34043798Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene
Q50425197Finding MyoD and lessons learned along the way.
Q71868228Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation
Q35098419Flipping the epigenetic switch
Q40650731Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine
Q37287575Free-radical polymer science structural cancer model: a review
Q35200012Frequency of reactivation and variability in expression of X-linked enzyme loci
Q30320562Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma
Q34581120Frequent epigenetic inactivation of cystatin M in breast carcinoma
Q73181730Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma
Q36944466Frequent hereditable shutdown of murine retrovirus gene expression in murine cell lines
Q43881636GH/IGF-1 Signaling and Current Knowledge of Epigenetics; a Review and Considerations on Possible Therapeutic Options.
Q53369902GSTP1 CpG island hypermethylation as a molecular marker of prostate cancer
Q28477278GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells
Q36914167Gamma interferon and 5-azacytidine cause transcriptional elevation of class I major histocompatibility complex gene expression in K562 leukemia cells in the absence of differentiation
Q55273665Gene Switching — A New Therapeutic Epoch: Discussion Paper
Q34471361Gene body methylation can alter gene expression and is a therapeutic target in cancer.
Q28481765Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions
Q40714185Gene silencing quantitatively controls the function of a developmental trans-activator
Q36767232Gene structure and transcription in mouse cells with extensively demethylated DNA.
Q34162510Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors
Q40174577Generation of phenotypic diversity and progression in metastatic tumor cells
Q36213162Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.
Q52451523Genotoxicity of 5-azacytidine in somatic cells of Drosophila
Q89934782Global DNA methylation and cognitive and behavioral outcomes at 4 years of age: A cross-sectional study
Q88555451Global DNA methylation synergistically regulates the nuclear and mitochondrial genomes in glioblastoma cells
Q34435865Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor
Q28072991Great expectations - Epigenetics and the meandering path from bench to bedside
Q36211210Growth control variant cell line having increased serum requirement and decreased response to platelet-derived growth factor: reversion by 5-azacytidine
Q36269512Growth hormone promotes the differentiation of myoblasts and preadipocytes generated by azacytidine treatment of 10T1/2 cells
Q54418210Growth inhibitory effects of 5-aza-2'-deoxycytidine in HL-60 promyelocytic leukemia cells resistant to differentiation induction
Q38854734Guadecitabine (SGI-110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin
Q33344484HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells
Q41587913HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR.
Q89559694Head regeneration and polarity reversal inHydra attenuata can occur in the absence of DNA synthesis
Q58768540HebbPlot: an intelligent tool for learning and visualizing chromatin mark signatures
Q28281505Helper T Cell Differentiation Is Controlled by the Cell Cycle
Q41557956Hemidemethylation is sufficient for chromatin relaxation and transcriptional activation of methylatedaprt gene in mouse P19 embryonal carcinoma cell line
Q35714613Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells
Q37706115Hemimethylation of DNA prevents chromatin expression
Q72739259Hemopoietic stem cells: Their roles in human leukemia and certain continuous cell lines
Q39503353Hepatitis B virus components produced by the human hepatoma cell line PLC/PRF/5: do they indicate virus propagation? Brief review
Q36199722Herbivore-Induced DNA Demethylation Changes Floral Signalling and Attractiveness to Pollinators in Brassica rapa
Q37031262High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects.
Q40680717High-Frequency Conversion to a “Fluffy” Developmental Phenotype in Aspergillus spp. by 5-Azacytidine Treatment: Evidence for Involvement of a Single Nuclear Gene
Q45804674High-Frequency Transfection and Cytopathology of the Hepatitis B Virus Core Antigen Gene in Human Cells
Q72751927High-frequency induction by 5-azacytidine of proline independence in CHO-K1 cells
Q84325850Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase
Q40582553Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines
Q38390185Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy.
Q43765659Human umbilical cord perivascular cells exhibit enhanced cardiomyocyte reprogramming and cardiac function after experimental acute myocardial infarction.
Q43251030Hydralazine target: from blood vessels to the epigenome
Q46063040Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition
Q41683480Hydroxylation of methylated DNA by TET1 in chondrocyte differentiation of C3H10T1/2 cells
Q41499278Hyperthermia and the heat-shock proteins of HeLa cells
Q85170660Hypomethylating agents in acute lymphoblastic leukemia: untapped potential?
Q35738022Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA Methylation
Q36280143Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein
Q96612896IN VIVO KINETICS OF THE GENOTOXIC AND CYTOTOXIC ACTIVITIES OF CLADRIBINE AND CLOFARABINE
Q37000576Identification of DNMT1 Selective Antagonists Using a Novel Scintillation Proximity Assay
Q39472965Identification of GLIPR1 tumor suppressor as methylation-silenced gene in acute myeloid leukemia by microarray analysis
Q36992178Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening
Q33789556Identification of novel DNA methylation inhibitors via a two-component reporter gene system
Q39118557Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia.
Q41565750Immunoglobulin gene expression and DNA methylation in murine pre-B cell lines
Q48104331Immunostaining for DNA Modifications: Computational Analysis of Confocal Images.
Q39831938Implications of tumor progression on clinical oncology
Q38529787Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer
Q45936827In Epigenetic Therapy, Less Is More
Q42018921In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein
Q53795391In the NEWS A QUICK ROUNDUP OF NEWS AND INFORMATION FROM OUR COMMUNITY.
Q36936864In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity
Q36297565In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells
Q33997187In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.
Q35740120Incorporation of 5-substituted analogs of deoxycytidine into DNA of herpes simplex virus-infected or - transformed cells without deamination to the thymidine analog
Q46010452Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase.
Q45804983Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA
Q36625233Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy
Q69099358Increased frequencies of sister chromatid exchanges at common fragile sites (1)(q42) and (19)(q13)
Q35518696Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy
Q36945486Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine
Q65002897Induction of chromosome decondensation, sister-chromatid exchanges and endoreduplications by 5-azacytidine, an inhibitor of DNA methylation
Q69123929Induction of class II major histocompatibility complex antigens in murine placenta by 5-azacytidine and interferon-gamma involves different cell populations
Q45206548Induction of cytidine deaminase in HL-60 myeloid leukemic cells by 5-AZA-2′-deoxycytidine
Q36689101Induction of heparin-binding EGF-like growth factor expression during myogenesis. Activation of the gene by MyoD and localization of the transmembrane form of the protein on the myotube surface
Q36294619Induction of prolactin-deficient variants of GH3 rat pituitary tumor cells by ethyl methanesulfonate: reversion by 5-azacytidine, a DNA methylation inhibitor
Q36695214Induction of replicative senescence by 5‐azacytidine: fundamental cell kinetic differences between human diploid fibroblasts and NIH‐3T3 cells
Q67279981Induction of retrovirus gene expression by selenium compounds
Q44403419Induction of sister chromatid exchanges by 5-fluorodeoxycytidine: correlation with DNA methylation
Q72675762Induction of thymidine kinase in enzyme-deficient chinese hamster cells
Q36944412Induction of α-Fetoprotein Synthesis in Differentiating F9 Teratocarcinoma Cells Is Accompanied by a Genome-Wide Loss of DNA Methylation
Q37974887Inflammation, DNA methylation and colitis-associated cancer
Q35009492Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women
Q72382487Influence of azacytidine on the induction of tyrosine aminotransferase and the NAD metabolism in rat liver
Q90332140Inhibition of DNA Methylation at the MLH1 Promoter Region Using Pyrrole-Imidazole Polyamide
Q72696362Inhibition of DNA Methylation by 5-Azacytidine
Q53219883Inhibition of DNA Methylation in Somatic Cells
Q44346779Inhibition of DNA methylation and reactivation of silenced genes by zebularine
Q72656874Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
Q36589313Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway
Q67535157Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro
Q77726587Inhibition of condensation in human chromosomes induced by the thymidine analogue 5-iododeoxyuridine
Q44517068Inhibition of condensation in the late-replicating X chromosome induced by 5-azadeoxycytidine in human lymphocyte cultures
Q71650766Inhibition of transcription in vitro by binding of DNA (cytosine-5)-methylases to DNA templates containing cytosine analogs
Q38644511Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors.
Q72678760Inhibitory effects of 5-azapyrimidine nucleosides on cellular immunity
Q37536018Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection
Q36254278Insulin-induced reactivation of an inactive herpes simplex thymidine kinase gene
Q58855590Interaction effects of 5-azacytidine with topoisomerase II inhibitors on CHO cells, as detected by cytogenetic analysis
Q40079991Interaction of viruses with tumor promotors
Q42123646Interferon-Gamma Directly Mediates Developmental Biliary Defects
Q36842359Interferon-induced revertants of ras-transformed cells: resistance to transformation by specific oncogenes and retransformation by 5-azacytidine
Q35012984Intratracheally Administered 5-Azacytidine Is Effective Against Orthotopic Human Lung Cancer Xenograft Models and Devoid of Important Systemic Toxicity
Q89707294Invited Reviews Epigenetics in neurodevelopment
Q28590301Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus
Q92637501LINC00162 confers sensitivity to 5-Aza-2'-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1
Q46837941Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidine
Q70194435Lack of correlation between thymidine kinase activity and the antiviral or antiproliferative response to interferon
Q37061240Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways
Q34994721Litter Gender Composition and Sex Affect Maternal Behavior and DNA Methylation Levels of the Oprm1 Gene in Rat Offspring
Q33911311Litter and sex effects on maternal behavior and DNA methylation of the Nr3c1 exon 17 promoter gene in hippocampus and cerebellum
Q48336497Local myogenic pulp-derived cell injection enhances craniofacial muscle regeneration in vivo
Q40500222Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells
Q36831746Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses
Q33668103MOM1 and Pol-IV/V interactions regulate the intensity and specificity of transcriptional gene silencing
Q36055095Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome
Q39688986Major histocompatibility antigens on trophoblast and their regulation: implications in the maternal-fetal relationship
Q92982393Making headway towards understanding how epigenetic mechanisms contribute to early-life effects
Q40134992Mammary Tumor Formation and Hormonal Control of Mouse Mammary Tumor Virus Expression
Q52533862Masc2, a gene from Ascobolus encoding a protein with a DNA-methyltransferase activity in vitro, is dispensable for in vivo methylation
Q35038158Maternal imprints and the origins of variation.
Q35219683Measuring whole genome methylation via oxygen channelling chemistry.
Q38797211Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges
Q34638690Mechanisms for the control of gene activity during development
Q39045061Mechanisms of pluripotency maintenance in mouse embryonic stem cells
Q33680168Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine
Q46347064Mesodermal cell determination and differentiation
Q34547269Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs
Q77801932Methods for in situ localization of proteins and DNA in the centromere-kinetochore complex
Q47128149Methylated claudin-11 associated with metastasis and poor survival of colorectal cancer
Q47572713Methylated-CpG island recovery assay-assisted microarrays for cancer diagnosis.
Q44281709Methylation and gene control
Q36977374Methylation and rearrangement of mouse intracisternal a particle genes in development, aging, and myeloma
Q36338022Methylation inhibitor therapy in the treatment of myelodysplastic syndrome
Q36412573Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement
Q43750764Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector
Q42034489Methylation of nuclear DNA in Physarum polycephalum
Q35271389Methylation of satellite sequences in mouse spermatogenic and somatic DNAs
Q38828730Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity
Q95811076Methylation of the HLA-DR alpha gene is positively correlated with expression
Q41848605Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage
Q54759183Methylation, aging, and pediatric acute lymphocytic leukemia.
Q40177205Methylation, expression and chromosomal position of genes in mammals
Q90727203Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury
Q35542218Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
Q40465100Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.
Q38172560Modification of the metastatic potential of tumor cells by drugs
Q40496167Modification of the methylation pattern in the vicinity of the chicken globin genes in avian erythroblastosis virus transformed cells
Q46064175Modulation of Igf2 Genomic Imprinting in Mice Induced by 5-Azacytidine, an Inhibitor of DNA Methylation
Q34324076Modulation of fetal hemoglobin in sickle cell anemia
Q58747194Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours
Q38146997Molecular insight in gastric cancer induction: an overview of cancer stemness genes.
Q72674944Molecular mechanism of extinction of liver-specific functions in mouse hepatoma � rat fibroblast hybrids: Extinction of the albumin gene
Q87476851Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes
Q36934269Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial
Q36282641Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes
Q33861548Murine muscle-specific enolase: cDNA cloning, sequence, and developmental expression
Q42614931Muscle tissue engineering and regeneration through epigenetic reprogramming and scaffold manipulation.
Q36145017Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase
Q28177221Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression
Q36981377Mutation at Autosomal Loci of Chinese Hamster Ovary Cells: Involvement of a High-Frequency Event Silencing Two Linked Alleles
Q47226740Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery.
Q37114055Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers
Q36926022Negative and positive regulation of human leukocyte antigen class I gene transcription in K562 leukemia cells
Q36867963Negative regulation of early polyomavirus expression in mouse embryonal carcinoma cells
Q84122086New agents in myelodysplastic syndromes
Q26851510New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells
Q34177689New insights into perinatal depression: pathogenesis and treatment during pregnancy and postpartum
Q28236190New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer
Q35829958Novel therapies for myelodysplastic syndromes
Q36654186Nucleic Acid Modifications in Regulation of Gene Expression
Q28473971Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors
Q40179547On a possible epigenetic mechanism(s) of tumor cell heterogeneity. The role of DNA methylation
Q33938463Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context
Q36338026Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection.
Q37033992Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype
Q41325243Overexpression of DNA Methyltransferase in Myoblast Cells Accelerates Myotube Formation
Q38459861Oxidative stress and DNA methylation regulation in the metabolic syndrome
Q41714964Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures
Q47833710PARPi potentiates with current conventional therapy in MLL leukemia
Q41742558PAX6 methylation and ectopic expression in human tumor cells
Q36831498PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.
Q40567400PFGE of human DNA: 5-azacytidine improves restriction
Q34326627Pathogenetic mechanisms in gastric cancer
Q33616120Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly
Q34185471Perspectives on the Discovery of Small-Molecule Modulators for Epigenetic Processes
Q46433479Pharmacodynamic and DNA methylation studies of high-dose 1-beta-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia
Q43247519Pharmacokinetic and pharmacodynamic analysis of 5-aza-2'-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy.
Q37866296Pharmacokinetic evaluation of decitabine for the treatment of leukemia
Q33738694Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.
Q44259986Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Q85397438Pharmacological profiles and clinical roles of 5-azacitidine (Vidaza^|^reg; for injection 100 mg) for the treatment of myelodysplastic syndrome (MDS)
Q37878207Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
Q35164242Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Q40419898Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response
Q72657219Phase I study on 5-aza-2′-deoxycytidine in children with acute leukemia
Q36973500Phenotypic switching in cells transformed with the herpes simplex virus thymidine kinase gene
Q36766471Physical linkage of mouse lambda genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequences
Q55132704Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells.
Q36871702Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes
Q43822201Potential of 5-aza-2′-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer
Q37313424Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy
Q36277821Pre-adipocyte determination either by insulin or by 5-azacytidine
Q27027751Predicting response to epigenetic therapy
Q36008593Procainamide is a specific inhibitor of DNA methyltransferase 1.
Q37278080Procaine inhibits the proliferation and DNA methylation in human hepatoma cells
Q37473768Profile of Peter A. Jones
Q44922040Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells.
Q33903052Prognostic factors associated with disease progression and overall survival in patients with myelodysplastic syndromes treated with decitabine
Q36358803Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
Q45985336Promoter-specific modulation of insulin-like growth factor II genomic imprinting by inhibitors of DNA methylation.
Q40680530Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine
Q45202926Protective effects of propolis on female rats’ histopathological, biochemical and genotoxic changes during LPS induced endotoxemia
Q34625614Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay
Q33231756Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings
Q39437887RASSF10 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin but Uncommon in Nevus Cell Nevi
Q52480362Radioprotective properties of DNA methylation-disrupting agents
Q35079955Rational Therapeutic Combinations with Histone Deacetylase Inhibitors for the Treatment of Cancer
Q34770617Reactivating the expression of methylation silenced genes in human cancer
Q36830020Reactivation of a methylation-silenced gene in adenovirus-transformed cells by 5-azacytidine or by E1A trans activation
Q40397023Reactivation of inactive X-linked genes
Q45072707Readers of DNA methylation, the MBD family as potential therapeutic targets.
Q42150134Recent Thymic Emigrants and Mature Naive T Cells Exhibit Differential DNA Methylation at Key Cytokine Loci
Q34633646Recurrent loss of specific introns during angiosperm evolution
Q72095713Region-specific methylation of the parathyroid hormone-related peptide gene determines its expression in human renal carcinoma cell lines
Q34117888Regulation of ALF gene expression in somatic and male germ line tissues involves partial and site-specific patterns of methylation
Q37248197Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition
Q42483974Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis
Q48181652Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis
Q46157205Repair-modification and evolution of the eukaryotic genome organization
Q41596117Repetitive 5-azacytidine treatments of Fao cells induce a stable and strong expression of gamma-glutamyl transpeptidase
Q33876297Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes
Q41686495Reprogramming of myosin light chain expression in muscle heterokaryons
Q53500275Reversal by 5-azacytidine of the S-adenosyl-l-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis
Q35199894Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocyte and fibroblast cultures
Q38895216Rewiring the solid tumor epigenome for cancer therapy
Q40731103Role for DNA methylation in the control of cell type specific maspin expression
Q92053513Role of DNA Methylation in the Development and Differentiation of Intestinal Epithelial Cells and Smooth Muscle Cells
Q50787017Role of DNA methylation in growth and differentiation in Physcomitrella patens and characterization of cytosine DNA methyltransferases.
Q33648531Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells
Q55219432Role of DNA methylation in the dietary restriction mediated cellular memory.
Q48655141Role of Human Nucleoside Transporters in the Uptake and Cytotoxicity of Azacitidine and Decitabine
Q36973335Role of Methylation in the Induced and Spontaneous Expression of the Avian Endogenous Virus ev-1: DNA Structure and Gene Products
Q33691162Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation
Q34712569Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.
Q42819228Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes
Q33959680Roles of cell division and gene transcription in the methylation of CpG islands.
Q71634269S-adenosyl-L-homocysteine: a non-cytotoxic hypomethylating agent
Q72383023SCE and DNA Methylation
Q39011822SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome
Q34345218Safety and clinical activity of 5-aza-2'-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia
Q40404791Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C5 methyltransferase of E. coli K-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine
Q33847891Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target
Q36845337Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy
Q37721708Sexual epigenetics: gender-specific methylation of a gene in the sex determining region of Populus balsamifera
Q36175129Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis
Q33793268Small molecules, big roles – the chemical manipulation of stem cell fate and somatic cell reprogramming
Q34628002Small-molecular modulators of cancer-associated epigenetic mechanisms
Q43869184Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster
Q41542828Specific Effects of 5-Fluoropyrimidines and 5-Azapyrimidines on Modification of the 5 Position of Pyrimidines, in Particular the Synthesis of 5-Methyluracil and 5-Methylcytosine in Nucleic Acids
Q36943862Spontaneous and 5-Azacytidine-Induced Reexpression of Ornithine Carbamoyl Transferase in Hepatoma Cells
Q37911654Standard Therapy for Patients With Myelodysplastic Syndromes
Q37774767Stem cells and the aging hematopoietic system
Q36530688Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers
Q59086851Studies of X chromosome DNA methylation in normal human cells
Q41248491Studies on DNA methyltransferase and alteration of the enzyme activity by chemical carcinogens
Q67535907Studies on the mechanism of the synergistic interaction between 2'-deoxy-5-azacytidine and cisplatin
Q37123428Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14.
Q72659524Synergistic effect ofcis-dichlorodiammineplatinum and 5-aza-2′-deoxycytidine on mouse leukemic cellsin vivo andin vitro
Q34434924Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness
Q69087304Synergistic induction of cytogenetic damage by alkylating antineoplastics and 5-azacytidine in human lymphocytes
Q28536924Synergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cells
Q42808871Synthesis of mucous glycoproteins by rabbit tracheal cells in vitro. Modulation by substratum, retinoids and cyclic AMP.
Q42196760Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2'-Deoxypseudoisocytidine.
Q35975551System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination
Q28822412Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine
Q43123082TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase
Q33600124Tackling the methylome: recent methodological advances in genome-wide methylation profiling
Q48125758Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut.
Q36769075Targeted transformation of Ascobolus immersus and de novo methylation of the resulting duplicated DNA sequences
Q91612129Targeting Chromatin Remodeling for Cancer Therapy
Q37320354Targeting DNA methylation
Q34258037Targeting DNA methylation for epigenetic therapy
Q38159805Targeting epigenetic mechanisms for clinical translation: enhancing the efficacy of tumor immunotherapies
Q92179985Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer
Q39721726Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
Q38821103Targeting the cancer epigenome for therapy
Q41983125Teratogenicity of 5‐azacytidine in the Sprague‐Dawley rat
Q47304223Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment.
Q35689206The 5-methylcytosine content of DNA from human tumors
Q58738685The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions
Q50072002The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
Q33937784The MspJI family of modification-dependent restriction endonucleases for epigenetic studies
Q38970507The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions
Q64108233The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome
Q36488272The Switch from Fetal to Adult Hemoglobin
Q46499006The USC Epigenome Center
Q44737509The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine
Q42961773The apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanisms.
Q37911496The application of delivery systems for DNA methyltransferase inhibitors
Q36415110The application of epigenetic modifiers on the treatment of prostate and bladder cancer
Q28828237The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements
Q36140349The characteristics of DNA methylation in an in vitro DNA synthesizing system from mouse fibroblasts
Q35744653The distribution of benzo(a)pyrene DNA adducts in mammalian chromatin
Q37731703The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation
Q35911372The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms
Q35985454The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life
Q89560455The effect of 5-azacytidine and cytidine analogs onDrosophila melanogaster cells in culture
Q72672747The effect of 5-azadeoxycytidine on cell growth and DNA methylation
Q72743109The effects of 5-azacytidine on the expression of the rat growth hormone gene. Methylation modulates but does not control growth hormone gene activity
Q35830928The effects of estrogen on prolactin gene methylation in normal and neoplastic rat pituitary tissues
Q37186709The epigenetics of adult (somatic) stem cells
Q37808106The epigenome as a therapeutic target in prostate cancer
Q28289975The epigenomics of cancer
Q37924576The epigenomics revolution in myelodysplasia: a clinico-pathological perspective
Q35140031The exit of mouse embryonic fibroblasts from the cell-cycle changes the nature of solvent exposure of the 5'-methylcytosine epitope within chromatin
Q56421597The fundamental role of epigenetic events in cancer
Q37061554The future of epigenetic therapy in solid tumours--lessons from the past.
Q42801517The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle
Q36972667The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells
Q34025643The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylation
Q41708839The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC in vitro and vivo
Q38218971The mechanistic role of DNA methylation in myeloid leukemogenesis
Q44391318The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine
Q93512100The methylation state of the T cell antigen receptor beta chain gene in subpopulations of mouse thymocytes
Q34258836The molecular genetics of human hemoglobin
Q42164554The pan-deacetylase inhibitor panobinostat modulates the expression of epithelial-mesenchymal transition markers in hepatocellular carcinoma models
Q38119782The promise and failures of epigenetic therapies for cancer treatment
Q42642766The role of DNA hypermethylation and demethylation in cancer and cancer therapy
Q35635538The role of DNA hypermethylation in the pathogenesis and prognosis of acute lymphoblastic leukemia
Q45804196The role of DNA methylation in virus replication: Inhibition of frog virus 3 replication by 5-azacytidine
Q26782771The role of chromatin modifications in somatic embryogenesis in plants
Q36681327The role of decitabine in the treatment of myelodysplastic syndromes
Q35996501The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes
Q28083603The role of piRNA and its potential clinical implications in cancer
Q36066276The silence of the genes: epigenetic disturbances in haematopoietic malignancies
Q34728015The social environment and the epigenome
Q40095644The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors
Q91612507The timeline of epigenetic drug discovery: from reality to dreams
Q52008880The turnip mutant of Arabidopsis reveals that LEAFY COTYLEDON1 expression mediates the effects of auxin and sugars to promote embryonic cell identity
Q40525198The use of 5-azacytidine to increase cleavage of methylation sensitive rare cutting restriction enzymes sites in amplified DNA
Q40464419Therapeutic spectrum in the treatment of myelodysplastic syndromes.
Q37765469Therapy with azanucleosides for myelodysplastic syndromes
Q40492466Tissue specificity and organisation of CpG methylation in calf satellite DNA I
Q46044781Tissue-Specific Imprinting of the Mouse Insulin-Like Growth Factor II Receptor Gene Correlates with Differential Allele-Specific DNA Methylation
Q36973783Topographical distribution of 5-methylcytosine in animal and plant DNA
Q41966277Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation
Q54551006Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus.
Q69098642Transcription of methylated viral DNA by eukaryotic RNA polymerase II
Q58616504Transcriptional Landscape of PARs in Epithelial Malignancies
Q28180053Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
Q36290263Transformation with DNA from 5-azacytidine-reactivated X chromosomes
Q39511011Transforming genes and target cells of murine spleen focus-forming viruses
Q35851931Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
Q46717074Trapped in action: direct visualization of DNA methyltransferase activity in living cells.
Q37679466Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues
Q37345034Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex
Q37022672Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy.
Q37079916Treatment strategies in myelodysplastic syndromes
Q50089369Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas
Q47568000Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads.
Q54476622Tumor progression, oncogenes and the evolution of metastatic phenotypic diversity
Q36655587Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer
Q59087668Unborn Children (Protection) Bill
Q34203924Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue
Q39906678Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes
Q35121110Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression
Q36100100Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells
Q35342673What do you mean, "epigenetic"?
Q37962016Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors
Q36894799X chromosome reactivation in mouse embryonal carcinoma cells
Q27639568Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases
Q80376979[DNA methylation on urinalysis and as a prognostic marker in urothelial cancer of the bladder]
Q89862635[Research Progress of Epigenetics in Pathogenesis and Treatment of Malignant Tumors]
Q36432360dNTP Supply Gene Expression Patterns after P53 Loss.
Q36890276p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.
Q36848202p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies
Q39916396p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia
Q72686110β-adrenergic receptor induction in HeLa cells: Synergistic effect of 5-azacytidine and butyrate

Search more.