scholarly article | Q13442814 |
P356 | DOI | 10.1016/0092-8674(80)90237-8 |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:0092867480902378?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:0092867480902378?httpAccept=text/xml | ||
P698 | PubMed publication ID | 6156004 |
P2093 | author name string | P. A. Jones | |
S. M. Taylor | |||
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Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine | Q34418477 | ||
Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines | Q37339666 | ||
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Measurement of S-adenosyl-l-methionine levels by SP sephadex chromatography | Q77375287 | ||
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P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA methylation | Q874745 |
P304 | page(s) | 85-93 | |
P577 | publication date | 1980-05-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Cellular differentiation, cytidine analogs and DNA methylation | |
P478 | volume | 20 |
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Q47594311 | 15N-enriched 5-fluorocytosine as a probe for examining unusual DNA structures |
Q36861123 | 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. |
Q42390503 | 2'-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation |
Q36341488 | 2′-Deoxyriboguanylurea, the primary breakdown product of 5-aza-2′-deoxyribocytidine, is a mutagen, an epimutagen, an inhibitor of DNA methyltransferases and an inducer of 5-azacytidine-type fragile sites |
Q41368389 | 3-Deazauridine (NSC 126849): an interesting modulator of biochemical response |
Q45117672 | 5-AZA-2′-deoxycytidine therapy in patients with acute leukemia inhibits DNA methylation |
Q43956186 | 5-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse |
Q36089887 | 5-Aza-2′-deoxycytidine Induced Growth Inhibition of Leukemia Cells through Modulating Endogenous Cholesterol Biosynthesis |
Q71603066 | 5-Azacytidine (NSC 102816) in refractory germ cell tumors. A phase II trial of the Eastern Cooperative Oncology Group |
Q72682311 | 5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia |
Q34770609 | 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy |
Q36029136 | 5-Azacytidine and 5-aza-2'-deoxycytidine behave as different antineoplastic agents in B16 melanoma |
Q43598858 | 5-Azacytidine induced inhibition of mitogenic response by agents that activate or augment activation of human peripheral blood T lymphocytes |
Q72725075 | 5-Azacytidine induced myogenesis in a differentiation defective cell line |
Q73740456 | 5-Azacytidine induces toxicity in PC12 cells by apoptosis |
Q36374978 | 5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation |
Q72722421 | 5-Azacytidine induction of thymidine kinase in a spontaneously enzyme-deficient murine tumor line |
Q33939486 | 5-Azacytidine is able to induce the conversion of teratocarcinoma-derived mesenchymal cells into epithelia cells |
Q36700438 | 5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression |
Q36829470 | 5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael |
Q40109774 | 5-Azacytidine, DNA Methylation, and Differentiation |
Q53565719 | 5-Azacytidine-Induced Reactivation of a Herpes Simplex Thymidine Kinase Gene |
Q41655228 | 5-Azacytidine-induced demethyelation of DNA to senescent level does not block proliferation of human fibroblasts |
Q62059622 | 5-Azacytidine-induced re-expression of alleles on the inactive X chromosome in a hybrid mouse cell line |
Q58555798 | 5-Azacytidine: A Promoter of Epigenetic Changes in the Quest to Improve Plant Somatic Embryogenesis |
Q36048217 | 5-Methylcytosine depletion during tumour development: An extension of the miscoding concept |
Q28262788 | 5-Methylcytosine, Gene Regulation, and Cancer |
Q40651597 | 5-aza-2'-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells |
Q43886449 | 5-aza-C-induced changes in the time of replication of the X chromosomes of Microtus agrestis are followed by non-random reversion to a late pattern of replication |
Q36250201 | 5-azacytidine and decitabine monotherapies of myelodysplastic disorders |
Q35232360 | 5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia |
Q33957840 | 5-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells |
Q72747497 | 5-azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: Evidence for regulatory genes controlling determination |
Q38014898 | 5-azacytosine compounds in medicinal chemistry: current stage and future perspectives |
Q37171158 | 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo |
Q28831002 | A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation |
Q41090697 | A Novel Aortic Smooth Muscle Cell Line Obtained from p53 Knock Out Mice Expresses Several Differentiation Characteristics |
Q26743743 | A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers |
Q37696774 | A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells |
Q21144289 | A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans |
Q24614467 | A decade of exploring the cancer epigenome — biological and translational implications |
Q36219130 | A growth factor-repressible gene associated with protein kinase C-mediated inhibition of adipocyte differentiation |
Q36159688 | A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase |
Q35794439 | A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy |
Q28333475 | A new insight into the histogenesis of 'mesodermomas'--malignant mesotheliomas |
Q50020673 | A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from TACL consortium |
Q35130668 | A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine, administered with tetrahydrouridine |
Q36682845 | A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome. |
Q35212344 | A pilot study of subcutaneous decitabine in β-thalassemia intermedia |
Q67487494 | A procedure for selecting mammalian cells with an impairment in oxidative phosphorylation |
Q35265834 | A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome |
Q36689145 | A prospective, multicenter, observational study of long-term decitabine treatment in patients with myelodysplastic syndrome |
Q34447578 | ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth |
Q28272449 | AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity |
Q38171316 | Aberrant DNA methylation in human cancers |
Q35075702 | Aberrant methylation of gene associated CpG sites occurs in borderline personality disorder |
Q40584383 | Aberrant methylation of integrin alpha4 gene in human gastric cancer cells. |
Q36223014 | Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells |
Q41553016 | Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets |
Q36008890 | Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus. |
Q36263881 | Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate |
Q72710915 | Activation of intracistemal a particles by 5-azacytidine in mouse Ki-BALB cell line |
Q45805408 | Activation of the epstein-barr virus genome by 5-aza-cytidine in latently infected human lymphoid lines |
Q41282882 | Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels |
Q36211517 | Adipocyte conversion of CHEF cells in serum-free medium |
Q36154766 | Advances in Genome-Wide DNA Methylation Analysis |
Q34312351 | Advances in treating acute myeloid leukemia |
Q38203863 | Age-related changes in DNA methylation: do they represent continued developmental changes? |
Q37410585 | Aging and epigenetic drift: a vicious cycle |
Q71068431 | Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis |
Q40110746 | Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis |
Q28394199 | Alzheimer’s Disease and Environmental Exposure to Lead: The Epidemiologic Evidence and Potential Role of Epigenetics |
Q35310832 | Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine |
Q57093404 | An epigenetic mechanism for cavefish eye degeneration |
Q28762983 | Analysis of tissue-specific differentially methylated regions (TDMs) in humans |
Q67535242 | Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes |
Q36345656 | Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma. |
Q25255934 | Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines |
Q34031951 | Application of Epigenome‐Modifying Small Molecules in Induced Pluripotent Stem Cells |
Q53552519 | Arabinosylcytosine Induces Fetal Hemoglobin in Baboons by Perturbing Erythroid Cell Differentiation Kinetics |
Q36047040 | Associations of ChREBP and Global DNA Methylation with Genetic and Environmental Factors in Chinese Healthy Adults |
Q42778979 | At the tipping point for epigenetic therapies in cancer |
Q35048054 | Augmenting antitumor immune responses with epigenetic modifying agents |
Q38838783 | Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives |
Q37645183 | Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines |
Q68973748 | Azacytidine-induced reactivation of adenosine deaminase in a murine cytotoxic T cell line |
Q35916793 | Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies |
Q40417006 | Binding of the EcoRII methylase to azacytosine-containing DNA. |
Q38328039 | Binding of the EcoRII methyltransferase to 5-fluorocytosine-containing DNA. Isolation of a bound peptide |
Q46401677 | Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice |
Q41403304 | Biological and molecular studies on Syrian hamster intracisternal R-type particles |
Q28307510 | Biological implications of the mechanism of action of human DNA (cytosine-5)methyltransferase |
Q37198930 | Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells |
Q37192659 | Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults |
Q35213136 | Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications |
Q37248365 | Breast cancer epigenetics: normal human mammary epithelial cells as a model system |
Q36895736 | Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells |
Q34690069 | Butyrate selectively activates the metallothionein gene in teratocarcinoma cells and induces hypersensitivity to metal induction |
Q33425892 | CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells |
Q39697060 | Can cancer chemotherapy enhance the malignant behaviour of tumours? |
Q37368971 | Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective |
Q35844494 | Cancer epigenetics: above and beyond |
Q35348043 | Cancer epigenetics: linking basic biology to clinical medicine. |
Q36293366 | Carcinogen- and radiation-transformed C3H 10T1/2 cells contain RNAs homologous to the long terminal repeat sequence of a murine leukemia virus |
Q36466174 | Carcinogenicity and haemoglobin synthesis induction by cytidine analogues |
Q54485278 | Cell cycle effects and cellular pharmacology of 5-AZA-2?-deoxycytidine |
Q42824627 | Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements |
Q36282892 | Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine |
Q33253085 | Cell kinetic disturbances induced by treatment of human diploid fibroblasts with 5-azacytidine indicate a major role for DNA methylation in the regulation of the chromosome cycle. |
Q72086896 | Cell-cycle dependent micronucleus formation and mitotic disturbances induced by 5-azacytidine in mammalian cells |
Q36970469 | Cellular Moloney Murine Sarcoma (c-mos) Sequences Are Hypermethylated and Transcriptionally Silent in Normal and Transformed Rodent Cells |
Q46174159 | Cellular metabolism of 1-beta-D-arabinofuranosyl-5-azacytosine and incorporation into DNA and RNA of human lymphoid CEM/0 and CEM/dCk(-) cells |
Q46008975 | Cellular metabolism of 5,6-dihydro-5-azacytidine and its incorporation into DNA and RNA of human lymphoid cells CEM/O and CEM/dCk(-). |
Q53565632 | Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine |
Q96428227 | Characterization of stress response involved in chicken myopathy |
Q33687040 | Characterization of the promoter region of the mouse Xist gene |
Q40422315 | Chemical synthesis of 2′-deoxyoligonucleotides containing 5-fluoro-2′-deoxycytidine |
Q40456209 | Chemical synthesis of 5-azacytidlne nucleotides and preparation of tRNAs containing 5-azacytidine in its 3′-terminus |
Q24806085 | Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites |
Q54369162 | Chemotherapy of L1210 and L1210/ARA-C leukemia with 5-aza-2'-deoxycytidine and 3-deazauridine |
Q59086364 | Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation |
Q37073231 | Chromatin, cancer and drug therapies |
Q38053238 | Clinical Results With the DNA Hypomethylating Agent 5-Aza-2′-Deoxycytidine (Decitabine) in Patients With Myelodysplastic Syndromes: An Update |
Q40109504 | Cloning of Contractile Protein Genes |
Q54503106 | Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII |
Q72611266 | Clustering of multiple transgene integrations in highly-unstable Ascobolus immersus transformants |
Q35838583 | Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs. |
Q38926364 | Combined analysis of DNA methylation and cell cycle in cancer cells |
Q34981266 | Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors |
Q67675052 | Comparison of antineoplastic activity of cytosine arabinoside and 5-aza-2′-deoxycytidine against human leukemic cells of different phenotype |
Q36466835 | Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia |
Q54664359 | Comparison of transformation efficiency of human active and inactive X-chromosomal DNA. |
Q35545116 | Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells |
Q91582166 | Contribution of promoter DNA sequence to heterochromatin formation velocity and memory of gene repression in mouse embryo fibroblasts |
Q72687822 | Controlling the fetal globin switch in man |
Q42480726 | Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus. |
Q40111142 | Conversion of iris epithelial cells as a model of differentiation control |
Q39695383 | Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements |
Q72721309 | Coreactivation of four inactive X genes in a hamster � human hybrid and persistence of late replication of reactivated X chromosome |
Q37576837 | Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine |
Q39139055 | CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors |
Q28131800 | CpG-rich islands and the function of DNA methylation |
Q71557465 | Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes |
Q40164069 | Cytoplasmic modification of nuclear gene expression |
Q35692564 | Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni. |
Q72664566 | Cytotoxic effects of butyrate and other ‘differentiation inducers’ on immature lymphoid cells |
Q67536246 | Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system |
Q37374120 | DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site |
Q38979940 | DNA Hypomethylating Drugs in Cancer Therapy |
Q57143629 | DNA Methylation Detection Using Resonance and Nanobowtie-Antenna-Enhanced Raman Spectroscopy |
Q34174778 | DNA Methylation and Demethylation in Mammals |
Q28263722 | DNA Methylation and Gene Function |
Q40109779 | DNA Methylation in Friend Erythroleukemia Cells: The Effects of Chemically Induced Differentiation and of Treatment with Inhibitors of DNA Methylation |
Q58860107 | DNA Methyltransferase Inhibitors |
Q39003558 | DNA Methyltransferase Inhibitors: Development and Applications. |
Q36654458 | DNA and histone methylation in gastric carcinogenesis |
Q24792540 | DNA and the chromosome - varied targets for chemotherapy |
Q34972245 | DNA demethylating antineoplastic strategies: a comparative point of view |
Q27011914 | DNA demethylation and invasive cancer: implications for therapeutics |
Q35200759 | DNA demethylation induced by 5-azacytidine does not affect fragile X expression |
Q37846279 | DNA hypermethylation as a chemotherapy target |
Q40527734 | DNA hypermethylation in gastric cancer |
Q39923092 | DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. |
Q34788574 | DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia. |
Q43735309 | DNA hypomethylation of karyoplasts for bovine nuclear transplantation. |
Q39208639 | DNA methylation aberrancies as a guide for surveillance and treatment of human cancers |
Q36925095 | DNA methylation affecting the expression of murine leukemia proviruses |
Q33875819 | DNA methylation and cancer |
Q33632335 | DNA methylation and chromatin modification. |
Q36581357 | DNA methylation and development |
Q30498513 | DNA methylation and differentiation |
Q36944389 | DNA methylation and expression of HLA-DR alpha |
Q37057353 | DNA methylation and gene expression |
Q40124163 | DNA methylation and its possible biological roles |
Q36951024 | DNA methylation and systemic lupus erythematosus |
Q41730013 | DNA methylation as a target for drug design |
Q58390463 | DNA methylation as a transcriptional regulator of the immune system |
Q33857557 | DNA methylation changes in a human cell model of breast cancer progression |
Q44970194 | DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium |
Q51256105 | DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells |
Q37723600 | DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay |
Q35149910 | DNA methylation dynamics in muscle development and disease |
Q36948603 | DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells |
Q36803766 | DNA methylation in breast and colorectal cancers |
Q40196814 | DNA methylation in eukaryotic cells. |
Q35594048 | DNA methylation in haematological malignancies: the role of decitabine |
Q26852141 | DNA methylation in mammals |
Q42825517 | DNA methylation in mouse cells in culture as measured by restriction enzymes |
Q100515583 | DNA methylation methods: global DNA methylation and methylomic analyses |
Q86738541 | DNA methylation of embryogenic carrot cell cultures and its variations as caused by mutation, differentiation, hormones and hypomethylating drugs |
Q37818614 | DNA methylation of genes in adipose tissue. |
Q36268174 | DNA methylation pattern is determined by the intracellular level of the methylase |
Q22065780 | DNA methylation patterns and epigenetic memory |
Q37188534 | DNA methylation patterns in lung carcinomas |
Q33669206 | DNA methylation prevents transfection of genes for specific surface antigens |
Q41333669 | DNA methylation: biology and significance |
Q36986433 | DNA methylation: its role in cancer development and therapy |
Q88511739 | DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine |
Q36910685 | DNA methyltransferase induced by frog virus 3 |
Q39671498 | DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer |
Q38040883 | DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences |
Q40109029 | DNA modification, differentiation, and transformation |
Q33615323 | DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine. |
Q36032155 | DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity |
Q39560130 | DNMT3B gene amplification predicts resistance to DNA demethylating drugs |
Q40453633 | De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. |
Q36302181 | De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells |
Q79373089 | Decitabine |
Q58603918 | Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy |
Q36118290 | Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing |
Q92705272 | Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice |
Q33392205 | Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience |
Q37568244 | Decitabine in the treatment of acute myeloid leukemia in elderly patients |
Q34088403 | Decitabine in the treatment of myelodysplastic syndromes. |
Q40997606 | Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus |
Q39319043 | Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation |
Q36284232 | Decitabine: a historical review of the development of an epigenetic drug |
Q38314204 | Decitabine: a promising epi-immunotherapeutic agent in solid tumors |
Q40352317 | Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome |
Q35643289 | Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines. |
Q30450911 | Delta-crystallin genes become hypomethylated in postmitotic lens cells during chicken development |
Q33678040 | Demethylating Agents in the Treatment of Cancer |
Q34847863 | Demethylating agents in myeloid malignancies |
Q45847197 | Demethylation by 5-azacytidine results in the expression of hepatitis B virus surface antigen in transgenic mice |
Q36848582 | Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression |
Q44590135 | Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres |
Q53549693 | Demethylation of the type I procollagen genes in transformed fibroblasts treated with 5-azacytidine |
Q43182059 | Dependence of transcriptional repression on CpG methylation density |
Q77225234 | Derepression of genes on the human inactive X chromosome: Evidence for differences in locus-specific rates of derepression and rates of transfer of active and inactive genes after DNA-mediated transformation |
Q59087665 | Derivation of macrophage-like lines from the pre-B lymphoma ABLS 8.1 using 5-azacytidine |
Q44023657 | Determination of purine and pyrimidine bases in DNA by micellar electrokinetic capillary chromatography with electrochemical detection |
Q52191554 | Development-dependent inheritance of 5-azacytidine-induced epimutations in triticale: analysis of rDNA expression patterns |
Q38630962 | Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers |
Q42243662 | Developmental activation of the H-2K gene is correlated with an increase in DNA methylation |
Q50014666 | Dietary Modulation of the Epigenome |
Q37163592 | Differential CpG island methylation of murine adenine nucleotide translocase genes |
Q36764112 | Differential activation of the hprt gene on the inactive X chromosome in primary and transformed Chinese hamster cells |
Q35365141 | Differential activity of DNA methyltransferase in the life cycle of Chlamydomonas reinhardi |
Q41279630 | Differential gene activity visualized on sister chromatids after replication in the presence of 5-azacytidine |
Q45866909 | Differential inhibition of sister chromatid condensation induced by 5-azadeoxycytidine in human chromosomes |
Q36920588 | Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance |
Q37336912 | Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains |
Q36323576 | Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate |
Q36260958 | Differentiation of myoblast cell lines and biological methylation: 3-deazaadenosine stimulates formation of multinucleated myofibers |
Q41201437 | Differentiation of smooth muscle phenotypes in mouse mesangial cells |
Q33409795 | Differentiation therapy of leukemia: 3 decades of development |
Q36523796 | Digging deep into "dirty" drugs - modulation of the methylation machinery |
Q57831457 | Distinct modes of DNA accessibility in plant chromatin |
Q40105518 | Dna Methylation in Eukaryote |
Q37371537 | Dnmt1 regulates the myogenic lineage specification of muscle stem cells |
Q24810666 | Down-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter region |
Q40040187 | Duck hepatitis B virus infection of Muscovy duck hepatocytes and nature of virus resistance in vivo |
Q36604669 | Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage |
Q38222879 | Early environment influences later performance in fishes |
Q37372837 | Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. |
Q36397293 | Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2. |
Q39552288 | Effect of 5-azacytidine on DNA methylation and on the enzymes of de novo pyrimidine biosynthesis in Bacillus subtilis Marburg strain |
Q72741862 | Effect of 5-azacytidine on deoxyribonucleic acid methylation in Escherichia coli K12 |
Q34410486 | Effect of 5-azacytidine on in vitro biofilm formation of Streptococcus pneumoniae |
Q40975583 | Effect of CpG methylation on expression of the mouse imprinted gene Mest. |
Q41651195 | Effect of Dibutyryl Cyclic Adenosine 3',5'-Monophosphate on Morphological Features and Biological Markers of Human Salivary Myoepithelial Cell Line in Culture |
Q39974567 | Effect of a new pyrimidine analog on Bacillus subtilis growth |
Q36847124 | Effect of cellular determination on oncogenic transformation by chemicals and oncogenes |
Q43860783 | Effect of cytidine analogs on cell growth and differentiation on a human neuroblastoma line |
Q36282015 | Effect of methylation on expression of microinjected genes |
Q40490079 | Effect of several inhibitors of enzymatic DNA methylation on thein vivomethylation of different classes of DNA sequences in a cultured human cell line |
Q35032927 | Effect of substratum and retinoids upon the mucosecretory differentiation of airway epithelial cells in vitro |
Q47936349 | Effects of 5-Azacytidine and Butyrate on Differentiation and Apoptosis of Hepatic Cancer Cell Lines |
Q36943333 | Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells |
Q72740318 | Effects of 5-azacytosine in DNA on enzymic uracil excision |
Q35824357 | Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells |
Q36762963 | Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
Q39639196 | Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors |
Q35750354 | Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine |
Q37381606 | Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. |
Q40006128 | Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells |
Q28488736 | Embryonic carcinoma cells show specific dielectric resistance profiles during induced differentiation |
Q37962013 | Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers |
Q36347785 | Endogenous retrovirus expression in stimulated murine lymphocytes. Identification of a new locus controlling mitogen induction of a defective virus |
Q36140986 | Engineering lymphocyte subsets: tools, trials and tribulations |
Q46886114 | Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs |
Q61642710 | Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine |
Q64915302 | Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations. |
Q37700733 | Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry |
Q44441820 | Epigenetic Characteristics and Development of Embryos Cloned from Donor Cells Treated by Trichostatin A or 5-aza-2′-deoxycytidine1 |
Q64998142 | Epigenetic Crosstalk between the Tumor Microenvironment and Ovarian Cancer Cells: A Therapeutic Road Less Traveled. |
Q38837858 | Epigenetic Determinants of Cancer |
Q37941536 | Epigenetic Drug Discovery: Targeting DNA Methyltransferases |
Q89996538 | Epigenetic Modification and Differentiation Induction of Malignant Glioma Cells by Oligo-Fucoidan |
Q64076648 | Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity |
Q38969422 | Epigenetic Regulation of the Thermogenic Adipose Program |
Q55433291 | Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia. |
Q38041528 | Epigenetic Targeting Therapies to Overcome Chemotherapy Resistance |
Q88669597 | Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion |
Q52674783 | Epigenetic Therapeutics and Their Impact in Immunotherapy of Lung Cancer. |
Q28072370 | Epigenetic Therapeutics: A New Weapon in the War Against Cancer |
Q33863567 | Epigenetic Therapies in MDS and AML |
Q38537883 | Epigenetic Therapy in Acute Myeloid Leukemia: Current and Future Directions |
Q36641966 | Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells |
Q38051195 | Epigenetic aspects of MDS and its molecular targeted therapy |
Q37969665 | Epigenetic cancer therapy: rationales, targets and drugs |
Q34385658 | Epigenetic changes in prostate cancer: implication for diagnosis and treatment |
Q33767309 | Epigenetic changes in the myelodysplastic syndrome. |
Q42409031 | Epigenetic control of epithelial-mesenchymal-transition in human cancer |
Q37854164 | Epigenetic control of gene regulation in plants |
Q55477773 | Epigenetic control of programmed cell death: inhibition by 5-azacytidine of 1,25-dihydroxyvitamin D3-induced programmed cell death in C6.9 glioma cells |
Q33740709 | Epigenetic deregulation in pediatric acute lymphoblastic leukemia. |
Q28305955 | Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer |
Q38986705 | Epigenetic drug discovery: breaking through the immune barrier |
Q26864455 | Epigenetic epidemiology: promises for public health research |
Q50132467 | Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance |
Q36310399 | Epigenetic mechanisms and gene networks in the nervous system. |
Q30489308 | Epigenetic mechanisms and the transgenerational effects of maternal care |
Q37789778 | Epigenetic mechanisms in senescence, immortalisation and cancer |
Q37412329 | Epigenetic mechanisms of regulation of Foxp3 expression |
Q37193994 | Epigenetic modifications of embryonic stem cells: current trends and relevance in developing regenerative medicine |
Q45976173 | Epigenetic modifiers: basic understanding and clinical development. |
Q37962586 | Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance |
Q38358635 | Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells |
Q36266756 | Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo |
Q38844664 | Epigenetic regulation in gallbladder cancer: Promoter methylation profiling as emergent novel biomarkers |
Q37850456 | Epigenetic regulation in myelodysplastic syndromes: implications for therapy |
Q39045550 | Epigenetic regulation of immune checkpoints: another target for cancer immunotherapy? |
Q48684687 | Epigenetic regulation of neural N-glycomics |
Q34498966 | Epigenetic regulation of pluripotency and differentiation |
Q36001910 | Epigenetic regulation of prostate cancer |
Q90208950 | Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to viral directed immunotherapy |
Q90010176 | Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma |
Q37567572 | Epigenetic therapeutics in autoimmune disease |
Q33621141 | Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. |
Q89652991 | Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitors |
Q38459836 | Epigenetic therapy for solid tumors: from bench science to clinical trials |
Q26745709 | Epigenetic therapy in gastrointestinal cancer: the right combination |
Q91361596 | Epigenetic therapy in immune-oncology |
Q38121995 | Epigenetic therapy in non-small-cell lung cancer: targeting DNA methyltransferases and histone deacetylases. |
Q38332497 | Epigenetic therapy of cancer stem and progenitor cells by targeting DNA methylation machineries |
Q36399557 | Epigenetic therapy of cancer: past, present and future |
Q36429559 | Epigenetic therapy with decitabine for myelodysplasia and leukemia |
Q37964702 | Epigenetic-based therapies in cancer: progress to date |
Q44555512 | Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines |
Q36449057 | Epigenetics as a Therapeutic Target in Breast Cancer |
Q29547437 | Epigenetics in human disease and prospects for epigenetic therapy |
Q26749113 | Epigenetics in non-small cell lung cancer: from basics to therapeutics |
Q24812104 | Epigenetics of cervical cancer. An overview and therapeutic perspectives |
Q36505767 | Epigenetics of lung cancer |
Q37785109 | Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics |
Q54765415 | Epigenetics, fragile X syndrome and transcriptional therapy. |
Q38770916 | Epigenetics: A primer for clinicians |
Q37992592 | Epigenetics: Concepts and relevance to IBD pathogenesis |
Q35118477 | Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor Suppressor Genes |
Q37078784 | Epigenomics and breast cancer |
Q35636575 | Epigenomics and ovarian carcinoma. |
Q37824255 | Epigenomics in cancer management |
Q33938743 | Epimutation of repeated genes in Ascobolus immersus |
Q28475641 | Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome |
Q38584326 | Eukaryotic DNA methylation |
Q34768789 | Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies |
Q28236365 | Evolutionary conservation of fragile sites induced by 5-azacytidine and 5-azadeoxycytidine in man, gorilla, and chimpanzee |
Q35563121 | Ex vivo expansion of human mobilized peripheral blood stem cells using epigenetic modifiers |
Q57205784 | Expression and Hypomethylation of α-Fetoprotein Gene in Unicentric and Multicentric Human Hepatocellular Carcinomas |
Q48944684 | Expression and methylation of the mouse alpha-fetoprotein gene in embryonic, adult, and neoplastic tissues |
Q53223510 | Expression and mutational analysis of Cip/Kip family in early glottic cancer |
Q28748604 | Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors |
Q35459761 | Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation |
Q37636759 | Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells. |
Q36316583 | Expression of transferred thymidine kinase genes is controlled by methylation |
Q34043798 | Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene |
Q50425197 | Finding MyoD and lessons learned along the way. |
Q71868228 | Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation |
Q35098419 | Flipping the epigenetic switch |
Q40650731 | Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine |
Q37287575 | Free-radical polymer science structural cancer model: a review |
Q35200012 | Frequency of reactivation and variability in expression of X-linked enzyme loci |
Q30320562 | Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma |
Q34581120 | Frequent epigenetic inactivation of cystatin M in breast carcinoma |
Q73181730 | Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma |
Q36944466 | Frequent hereditable shutdown of murine retrovirus gene expression in murine cell lines |
Q43881636 | GH/IGF-1 Signaling and Current Knowledge of Epigenetics; a Review and Considerations on Possible Therapeutic Options. |
Q53369902 | GSTP1 CpG island hypermethylation as a molecular marker of prostate cancer |
Q28477278 | GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells |
Q36914167 | Gamma interferon and 5-azacytidine cause transcriptional elevation of class I major histocompatibility complex gene expression in K562 leukemia cells in the absence of differentiation |
Q55273665 | Gene Switching — A New Therapeutic Epoch: Discussion Paper |
Q34471361 | Gene body methylation can alter gene expression and is a therapeutic target in cancer. |
Q28481765 | Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions |
Q40714185 | Gene silencing quantitatively controls the function of a developmental trans-activator |
Q36767232 | Gene structure and transcription in mouse cells with extensively demethylated DNA. |
Q34162510 | Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors |
Q40174577 | Generation of phenotypic diversity and progression in metastatic tumor cells |
Q36213162 | Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men. |
Q52451523 | Genotoxicity of 5-azacytidine in somatic cells of Drosophila |
Q89934782 | Global DNA methylation and cognitive and behavioral outcomes at 4 years of age: A cross-sectional study |
Q88555451 | Global DNA methylation synergistically regulates the nuclear and mitochondrial genomes in glioblastoma cells |
Q34435865 | Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor |
Q28072991 | Great expectations - Epigenetics and the meandering path from bench to bedside |
Q36211210 | Growth control variant cell line having increased serum requirement and decreased response to platelet-derived growth factor: reversion by 5-azacytidine |
Q36269512 | Growth hormone promotes the differentiation of myoblasts and preadipocytes generated by azacytidine treatment of 10T1/2 cells |
Q54418210 | Growth inhibitory effects of 5-aza-2'-deoxycytidine in HL-60 promyelocytic leukemia cells resistant to differentiation induction |
Q38854734 | Guadecitabine (SGI-110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin |
Q33344484 | HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells |
Q41587913 | HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR. |
Q89559694 | Head regeneration and polarity reversal inHydra attenuata can occur in the absence of DNA synthesis |
Q58768540 | HebbPlot: an intelligent tool for learning and visualizing chromatin mark signatures |
Q28281505 | Helper T Cell Differentiation Is Controlled by the Cell Cycle |
Q41557956 | Hemidemethylation is sufficient for chromatin relaxation and transcriptional activation of methylatedaprt gene in mouse P19 embryonal carcinoma cell line |
Q35714613 | Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells |
Q37706115 | Hemimethylation of DNA prevents chromatin expression |
Q72739259 | Hemopoietic stem cells: Their roles in human leukemia and certain continuous cell lines |
Q39503353 | Hepatitis B virus components produced by the human hepatoma cell line PLC/PRF/5: do they indicate virus propagation? Brief review |
Q36199722 | Herbivore-Induced DNA Demethylation Changes Floral Signalling and Attractiveness to Pollinators in Brassica rapa |
Q37031262 | High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects. |
Q40680717 | High-Frequency Conversion to a “Fluffy” Developmental Phenotype in Aspergillus spp. by 5-Azacytidine Treatment: Evidence for Involvement of a Single Nuclear Gene |
Q45804674 | High-Frequency Transfection and Cytopathology of the Hepatitis B Virus Core Antigen Gene in Human Cells |
Q72751927 | High-frequency induction by 5-azacytidine of proline independence in CHO-K1 cells |
Q84325850 | Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase |
Q40582553 | Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines |
Q38390185 | Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy. |
Q43765659 | Human umbilical cord perivascular cells exhibit enhanced cardiomyocyte reprogramming and cardiac function after experimental acute myocardial infarction. |
Q43251030 | Hydralazine target: from blood vessels to the epigenome |
Q46063040 | Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition |
Q41683480 | Hydroxylation of methylated DNA by TET1 in chondrocyte differentiation of C3H10T1/2 cells |
Q41499278 | Hyperthermia and the heat-shock proteins of HeLa cells |
Q85170660 | Hypomethylating agents in acute lymphoblastic leukemia: untapped potential? |
Q35738022 | Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA Methylation |
Q36280143 | Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein |
Q96612896 | IN VIVO KINETICS OF THE GENOTOXIC AND CYTOTOXIC ACTIVITIES OF CLADRIBINE AND CLOFARABINE |
Q37000576 | Identification of DNMT1 Selective Antagonists Using a Novel Scintillation Proximity Assay |
Q39472965 | Identification of GLIPR1 tumor suppressor as methylation-silenced gene in acute myeloid leukemia by microarray analysis |
Q36992178 | Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening |
Q33789556 | Identification of novel DNA methylation inhibitors via a two-component reporter gene system |
Q39118557 | Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia. |
Q41565750 | Immunoglobulin gene expression and DNA methylation in murine pre-B cell lines |
Q48104331 | Immunostaining for DNA Modifications: Computational Analysis of Confocal Images. |
Q39831938 | Implications of tumor progression on clinical oncology |
Q38529787 | Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer |
Q45936827 | In Epigenetic Therapy, Less Is More |
Q42018921 | In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein |
Q53795391 | In the NEWS A QUICK ROUNDUP OF NEWS AND INFORMATION FROM OUR COMMUNITY. |
Q36936864 | In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity |
Q36297565 | In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells |
Q33997187 | In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. |
Q35740120 | Incorporation of 5-substituted analogs of deoxycytidine into DNA of herpes simplex virus-infected or - transformed cells without deamination to the thymidine analog |
Q46010452 | Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase. |
Q45804983 | Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA |
Q36625233 | Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy |
Q69099358 | Increased frequencies of sister chromatid exchanges at common fragile sites (1)(q42) and (19)(q13) |
Q35518696 | Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy |
Q36945486 | Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine |
Q65002897 | Induction of chromosome decondensation, sister-chromatid exchanges and endoreduplications by 5-azacytidine, an inhibitor of DNA methylation |
Q69123929 | Induction of class II major histocompatibility complex antigens in murine placenta by 5-azacytidine and interferon-gamma involves different cell populations |
Q45206548 | Induction of cytidine deaminase in HL-60 myeloid leukemic cells by 5-AZA-2′-deoxycytidine |
Q36689101 | Induction of heparin-binding EGF-like growth factor expression during myogenesis. Activation of the gene by MyoD and localization of the transmembrane form of the protein on the myotube surface |
Q36294619 | Induction of prolactin-deficient variants of GH3 rat pituitary tumor cells by ethyl methanesulfonate: reversion by 5-azacytidine, a DNA methylation inhibitor |
Q36695214 | Induction of replicative senescence by 5‐azacytidine: fundamental cell kinetic differences between human diploid fibroblasts and NIH‐3T3 cells |
Q67279981 | Induction of retrovirus gene expression by selenium compounds |
Q44403419 | Induction of sister chromatid exchanges by 5-fluorodeoxycytidine: correlation with DNA methylation |
Q72675762 | Induction of thymidine kinase in enzyme-deficient chinese hamster cells |
Q36944412 | Induction of α-Fetoprotein Synthesis in Differentiating F9 Teratocarcinoma Cells Is Accompanied by a Genome-Wide Loss of DNA Methylation |
Q37974887 | Inflammation, DNA methylation and colitis-associated cancer |
Q35009492 | Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women |
Q72382487 | Influence of azacytidine on the induction of tyrosine aminotransferase and the NAD metabolism in rat liver |
Q90332140 | Inhibition of DNA Methylation at the MLH1 Promoter Region Using Pyrrole-Imidazole Polyamide |
Q72696362 | Inhibition of DNA Methylation by 5-Azacytidine |
Q53219883 | Inhibition of DNA Methylation in Somatic Cells |
Q44346779 | Inhibition of DNA methylation and reactivation of silenced genes by zebularine |
Q72656874 | Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine |
Q36589313 | Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway |
Q67535157 | Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro |
Q77726587 | Inhibition of condensation in human chromosomes induced by the thymidine analogue 5-iododeoxyuridine |
Q44517068 | Inhibition of condensation in the late-replicating X chromosome induced by 5-azadeoxycytidine in human lymphocyte cultures |
Q71650766 | Inhibition of transcription in vitro by binding of DNA (cytosine-5)-methylases to DNA templates containing cytosine analogs |
Q38644511 | Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors. |
Q72678760 | Inhibitory effects of 5-azapyrimidine nucleosides on cellular immunity |
Q37536018 | Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection |
Q36254278 | Insulin-induced reactivation of an inactive herpes simplex thymidine kinase gene |
Q58855590 | Interaction effects of 5-azacytidine with topoisomerase II inhibitors on CHO cells, as detected by cytogenetic analysis |
Q40079991 | Interaction of viruses with tumor promotors |
Q42123646 | Interferon-Gamma Directly Mediates Developmental Biliary Defects |
Q36842359 | Interferon-induced revertants of ras-transformed cells: resistance to transformation by specific oncogenes and retransformation by 5-azacytidine |
Q35012984 | Intratracheally Administered 5-Azacytidine Is Effective Against Orthotopic Human Lung Cancer Xenograft Models and Devoid of Important Systemic Toxicity |
Q89707294 | Invited Reviews Epigenetics in neurodevelopment |
Q28590301 | Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus |
Q92637501 | LINC00162 confers sensitivity to 5-Aza-2'-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1 |
Q46837941 | Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidine |
Q70194435 | Lack of correlation between thymidine kinase activity and the antiviral or antiproliferative response to interferon |
Q37061240 | Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways |
Q34994721 | Litter Gender Composition and Sex Affect Maternal Behavior and DNA Methylation Levels of the Oprm1 Gene in Rat Offspring |
Q33911311 | Litter and sex effects on maternal behavior and DNA methylation of the Nr3c1 exon 17 promoter gene in hippocampus and cerebellum |
Q48336497 | Local myogenic pulp-derived cell injection enhances craniofacial muscle regeneration in vivo |
Q40500222 | Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells |
Q36831746 | Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses |
Q33668103 | MOM1 and Pol-IV/V interactions regulate the intensity and specificity of transcriptional gene silencing |
Q36055095 | Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome |
Q39688986 | Major histocompatibility antigens on trophoblast and their regulation: implications in the maternal-fetal relationship |
Q92982393 | Making headway towards understanding how epigenetic mechanisms contribute to early-life effects |
Q40134992 | Mammary Tumor Formation and Hormonal Control of Mouse Mammary Tumor Virus Expression |
Q52533862 | Masc2, a gene from Ascobolus encoding a protein with a DNA-methyltransferase activity in vitro, is dispensable for in vivo methylation |
Q35038158 | Maternal imprints and the origins of variation. |
Q35219683 | Measuring whole genome methylation via oxygen channelling chemistry. |
Q38797211 | Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges |
Q34638690 | Mechanisms for the control of gene activity during development |
Q39045061 | Mechanisms of pluripotency maintenance in mouse embryonic stem cells |
Q33680168 | Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine |
Q46347064 | Mesodermal cell determination and differentiation |
Q34547269 | Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs |
Q77801932 | Methods for in situ localization of proteins and DNA in the centromere-kinetochore complex |
Q47128149 | Methylated claudin-11 associated with metastasis and poor survival of colorectal cancer |
Q47572713 | Methylated-CpG island recovery assay-assisted microarrays for cancer diagnosis. |
Q44281709 | Methylation and gene control |
Q36977374 | Methylation and rearrangement of mouse intracisternal a particle genes in development, aging, and myeloma |
Q36338022 | Methylation inhibitor therapy in the treatment of myelodysplastic syndrome |
Q36412573 | Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement |
Q43750764 | Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector |
Q42034489 | Methylation of nuclear DNA in Physarum polycephalum |
Q35271389 | Methylation of satellite sequences in mouse spermatogenic and somatic DNAs |
Q38828730 | Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity |
Q95811076 | Methylation of the HLA-DR alpha gene is positively correlated with expression |
Q41848605 | Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage |
Q54759183 | Methylation, aging, and pediatric acute lymphocytic leukemia. |
Q40177205 | Methylation, expression and chromosomal position of genes in mammals |
Q90727203 | Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury |
Q35542218 | Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts |
Q40465100 | Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine. |
Q38172560 | Modification of the metastatic potential of tumor cells by drugs |
Q40496167 | Modification of the methylation pattern in the vicinity of the chicken globin genes in avian erythroblastosis virus transformed cells |
Q46064175 | Modulation of Igf2 Genomic Imprinting in Mice Induced by 5-Azacytidine, an Inhibitor of DNA Methylation |
Q34324076 | Modulation of fetal hemoglobin in sickle cell anemia |
Q58747194 | Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours |
Q38146997 | Molecular insight in gastric cancer induction: an overview of cancer stemness genes. |
Q72674944 | Molecular mechanism of extinction of liver-specific functions in mouse hepatoma � rat fibroblast hybrids: Extinction of the albumin gene |
Q87476851 | Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes |
Q36934269 | Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial |
Q36282641 | Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes |
Q33861548 | Murine muscle-specific enolase: cDNA cloning, sequence, and developmental expression |
Q42614931 | Muscle tissue engineering and regeneration through epigenetic reprogramming and scaffold manipulation. |
Q36145017 | Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase |
Q28177221 | Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression |
Q36981377 | Mutation at Autosomal Loci of Chinese Hamster Ovary Cells: Involvement of a High-Frequency Event Silencing Two Linked Alleles |
Q47226740 | Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery. |
Q37114055 | Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers |
Q36926022 | Negative and positive regulation of human leukocyte antigen class I gene transcription in K562 leukemia cells |
Q36867963 | Negative regulation of early polyomavirus expression in mouse embryonal carcinoma cells |
Q84122086 | New agents in myelodysplastic syndromes |
Q26851510 | New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells |
Q34177689 | New insights into perinatal depression: pathogenesis and treatment during pregnancy and postpartum |
Q28236190 | New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer |
Q35829958 | Novel therapies for myelodysplastic syndromes |
Q36654186 | Nucleic Acid Modifications in Regulation of Gene Expression |
Q28473971 | Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors |
Q40179547 | On a possible epigenetic mechanism(s) of tumor cell heterogeneity. The role of DNA methylation |
Q33938463 | Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context |
Q36338026 | Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection. |
Q37033992 | Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype |
Q41325243 | Overexpression of DNA Methyltransferase in Myoblast Cells Accelerates Myotube Formation |
Q38459861 | Oxidative stress and DNA methylation regulation in the metabolic syndrome |
Q41714964 | Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures |
Q47833710 | PARPi potentiates with current conventional therapy in MLL leukemia |
Q41742558 | PAX6 methylation and ectopic expression in human tumor cells |
Q36831498 | PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells. |
Q40567400 | PFGE of human DNA: 5-azacytidine improves restriction |
Q34326627 | Pathogenetic mechanisms in gastric cancer |
Q33616120 | Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly |
Q34185471 | Perspectives on the Discovery of Small-Molecule Modulators for Epigenetic Processes |
Q46433479 | Pharmacodynamic and DNA methylation studies of high-dose 1-beta-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia |
Q43247519 | Pharmacokinetic and pharmacodynamic analysis of 5-aza-2'-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy. |
Q37866296 | Pharmacokinetic evaluation of decitabine for the treatment of leukemia |
Q33738694 | Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. |
Q44259986 | Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. |
Q85397438 | Pharmacological profiles and clinical roles of 5-azacitidine (Vidaza^|^reg; for injection 100 mg) for the treatment of myelodysplastic syndrome (MDS) |
Q37878207 | Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs |
Q35164242 | Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML. |
Q40419898 | Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response |
Q72657219 | Phase I study on 5-aza-2′-deoxycytidine in children with acute leukemia |
Q36973500 | Phenotypic switching in cells transformed with the herpes simplex virus thymidine kinase gene |
Q36766471 | Physical linkage of mouse lambda genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequences |
Q55132704 | Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells. |
Q36871702 | Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes |
Q43822201 | Potential of 5-aza-2′-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer |
Q37313424 | Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy |
Q36277821 | Pre-adipocyte determination either by insulin or by 5-azacytidine |
Q27027751 | Predicting response to epigenetic therapy |
Q36008593 | Procainamide is a specific inhibitor of DNA methyltransferase 1. |
Q37278080 | Procaine inhibits the proliferation and DNA methylation in human hepatoma cells |
Q37473768 | Profile of Peter A. Jones |
Q44922040 | Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells. |
Q33903052 | Prognostic factors associated with disease progression and overall survival in patients with myelodysplastic syndromes treated with decitabine |
Q36358803 | Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma |
Q45985336 | Promoter-specific modulation of insulin-like growth factor II genomic imprinting by inhibitors of DNA methylation. |
Q40680530 | Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine |
Q45202926 | Protective effects of propolis on female rats’ histopathological, biochemical and genotoxic changes during LPS induced endotoxemia |
Q34625614 | Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay |
Q33231756 | Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings |
Q39437887 | RASSF10 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin but Uncommon in Nevus Cell Nevi |
Q52480362 | Radioprotective properties of DNA methylation-disrupting agents |
Q35079955 | Rational Therapeutic Combinations with Histone Deacetylase Inhibitors for the Treatment of Cancer |
Q34770617 | Reactivating the expression of methylation silenced genes in human cancer |
Q36830020 | Reactivation of a methylation-silenced gene in adenovirus-transformed cells by 5-azacytidine or by E1A trans activation |
Q40397023 | Reactivation of inactive X-linked genes |
Q45072707 | Readers of DNA methylation, the MBD family as potential therapeutic targets. |
Q42150134 | Recent Thymic Emigrants and Mature Naive T Cells Exhibit Differential DNA Methylation at Key Cytokine Loci |
Q34633646 | Recurrent loss of specific introns during angiosperm evolution |
Q72095713 | Region-specific methylation of the parathyroid hormone-related peptide gene determines its expression in human renal carcinoma cell lines |
Q34117888 | Regulation of ALF gene expression in somatic and male germ line tissues involves partial and site-specific patterns of methylation |
Q37248197 | Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition |
Q42483974 | Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis |
Q48181652 | Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis |
Q46157205 | Repair-modification and evolution of the eukaryotic genome organization |
Q41596117 | Repetitive 5-azacytidine treatments of Fao cells induce a stable and strong expression of gamma-glutamyl transpeptidase |
Q33876297 | Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes |
Q41686495 | Reprogramming of myosin light chain expression in muscle heterokaryons |
Q53500275 | Reversal by 5-azacytidine of the S-adenosyl-l-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis |
Q35199894 | Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocyte and fibroblast cultures |
Q38895216 | Rewiring the solid tumor epigenome for cancer therapy |
Q40731103 | Role for DNA methylation in the control of cell type specific maspin expression |
Q92053513 | Role of DNA Methylation in the Development and Differentiation of Intestinal Epithelial Cells and Smooth Muscle Cells |
Q50787017 | Role of DNA methylation in growth and differentiation in Physcomitrella patens and characterization of cytosine DNA methyltransferases. |
Q33648531 | Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells |
Q55219432 | Role of DNA methylation in the dietary restriction mediated cellular memory. |
Q48655141 | Role of Human Nucleoside Transporters in the Uptake and Cytotoxicity of Azacitidine and Decitabine |
Q36973335 | Role of Methylation in the Induced and Spontaneous Expression of the Avian Endogenous Virus ev-1: DNA Structure and Gene Products |
Q33691162 | Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation |
Q34712569 | Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. |
Q42819228 | Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes |
Q33959680 | Roles of cell division and gene transcription in the methylation of CpG islands. |
Q71634269 | S-adenosyl-L-homocysteine: a non-cytotoxic hypomethylating agent |
Q72383023 | SCE and DNA Methylation |
Q39011822 | SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome |
Q34345218 | Safety and clinical activity of 5-aza-2'-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia |
Q40404791 | Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C5 methyltransferase of E. coli K-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine |
Q33847891 | Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target |
Q36845337 | Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy |
Q37721708 | Sexual epigenetics: gender-specific methylation of a gene in the sex determining region of Populus balsamifera |
Q36175129 | Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis |
Q33793268 | Small molecules, big roles – the chemical manipulation of stem cell fate and somatic cell reprogramming |
Q34628002 | Small-molecular modulators of cancer-associated epigenetic mechanisms |
Q43869184 | Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster |
Q41542828 | Specific Effects of 5-Fluoropyrimidines and 5-Azapyrimidines on Modification of the 5 Position of Pyrimidines, in Particular the Synthesis of 5-Methyluracil and 5-Methylcytosine in Nucleic Acids |
Q36943862 | Spontaneous and 5-Azacytidine-Induced Reexpression of Ornithine Carbamoyl Transferase in Hepatoma Cells |
Q37911654 | Standard Therapy for Patients With Myelodysplastic Syndromes |
Q37774767 | Stem cells and the aging hematopoietic system |
Q36530688 | Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers |
Q59086851 | Studies of X chromosome DNA methylation in normal human cells |
Q41248491 | Studies on DNA methyltransferase and alteration of the enzyme activity by chemical carcinogens |
Q67535907 | Studies on the mechanism of the synergistic interaction between 2'-deoxy-5-azacytidine and cisplatin |
Q37123428 | Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14. |
Q72659524 | Synergistic effect ofcis-dichlorodiammineplatinum and 5-aza-2′-deoxycytidine on mouse leukemic cellsin vivo andin vitro |
Q34434924 | Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness |
Q69087304 | Synergistic induction of cytogenetic damage by alkylating antineoplastics and 5-azacytidine in human lymphocytes |
Q28536924 | Synergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cells |
Q42808871 | Synthesis of mucous glycoproteins by rabbit tracheal cells in vitro. Modulation by substratum, retinoids and cyclic AMP. |
Q42196760 | Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2'-Deoxypseudoisocytidine. |
Q35975551 | System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination |
Q28822412 | Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine |
Q43123082 | TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase |
Q33600124 | Tackling the methylome: recent methodological advances in genome-wide methylation profiling |
Q48125758 | Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut. |
Q36769075 | Targeted transformation of Ascobolus immersus and de novo methylation of the resulting duplicated DNA sequences |
Q91612129 | Targeting Chromatin Remodeling for Cancer Therapy |
Q37320354 | Targeting DNA methylation |
Q34258037 | Targeting DNA methylation for epigenetic therapy |
Q38159805 | Targeting epigenetic mechanisms for clinical translation: enhancing the efficacy of tumor immunotherapies |
Q92179985 | Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer |
Q39721726 | Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme |
Q38821103 | Targeting the cancer epigenome for therapy |
Q41983125 | Teratogenicity of 5‐azacytidine in the Sprague‐Dawley rat |
Q47304223 | Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment. |
Q35689206 | The 5-methylcytosine content of DNA from human tumors |
Q58738685 | The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions |
Q50072002 | The DNA methyltransferase family: a versatile toolkit for epigenetic regulation |
Q33937784 | The MspJI family of modification-dependent restriction endonucleases for epigenetic studies |
Q38970507 | The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions |
Q64108233 | The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome |
Q36488272 | The Switch from Fetal to Adult Hemoglobin |
Q46499006 | The USC Epigenome Center |
Q44737509 | The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine |
Q42961773 | The apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanisms. |
Q37911496 | The application of delivery systems for DNA methyltransferase inhibitors |
Q36415110 | The application of epigenetic modifiers on the treatment of prostate and bladder cancer |
Q28828237 | The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements |
Q36140349 | The characteristics of DNA methylation in an in vitro DNA synthesizing system from mouse fibroblasts |
Q35744653 | The distribution of benzo(a)pyrene DNA adducts in mammalian chromatin |
Q37731703 | The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation |
Q35911372 | The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms |
Q35985454 | The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life |
Q89560455 | The effect of 5-azacytidine and cytidine analogs onDrosophila melanogaster cells in culture |
Q72672747 | The effect of 5-azadeoxycytidine on cell growth and DNA methylation |
Q72743109 | The effects of 5-azacytidine on the expression of the rat growth hormone gene. Methylation modulates but does not control growth hormone gene activity |
Q35830928 | The effects of estrogen on prolactin gene methylation in normal and neoplastic rat pituitary tissues |
Q37186709 | The epigenetics of adult (somatic) stem cells |
Q37808106 | The epigenome as a therapeutic target in prostate cancer |
Q28289975 | The epigenomics of cancer |
Q37924576 | The epigenomics revolution in myelodysplasia: a clinico-pathological perspective |
Q35140031 | The exit of mouse embryonic fibroblasts from the cell-cycle changes the nature of solvent exposure of the 5'-methylcytosine epitope within chromatin |
Q56421597 | The fundamental role of epigenetic events in cancer |
Q37061554 | The future of epigenetic therapy in solid tumours--lessons from the past. |
Q42801517 | The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle |
Q36972667 | The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells |
Q34025643 | The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylation |
Q41708839 | The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC in vitro and vivo |
Q38218971 | The mechanistic role of DNA methylation in myeloid leukemogenesis |
Q44391318 | The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine |
Q93512100 | The methylation state of the T cell antigen receptor beta chain gene in subpopulations of mouse thymocytes |
Q34258836 | The molecular genetics of human hemoglobin |
Q42164554 | The pan-deacetylase inhibitor panobinostat modulates the expression of epithelial-mesenchymal transition markers in hepatocellular carcinoma models |
Q38119782 | The promise and failures of epigenetic therapies for cancer treatment |
Q42642766 | The role of DNA hypermethylation and demethylation in cancer and cancer therapy |
Q35635538 | The role of DNA hypermethylation in the pathogenesis and prognosis of acute lymphoblastic leukemia |
Q45804196 | The role of DNA methylation in virus replication: Inhibition of frog virus 3 replication by 5-azacytidine |
Q26782771 | The role of chromatin modifications in somatic embryogenesis in plants |
Q36681327 | The role of decitabine in the treatment of myelodysplastic syndromes |
Q35996501 | The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes |
Q28083603 | The role of piRNA and its potential clinical implications in cancer |
Q36066276 | The silence of the genes: epigenetic disturbances in haematopoietic malignancies |
Q34728015 | The social environment and the epigenome |
Q40095644 | The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors |
Q91612507 | The timeline of epigenetic drug discovery: from reality to dreams |
Q52008880 | The turnip mutant of Arabidopsis reveals that LEAFY COTYLEDON1 expression mediates the effects of auxin and sugars to promote embryonic cell identity |
Q40525198 | The use of 5-azacytidine to increase cleavage of methylation sensitive rare cutting restriction enzymes sites in amplified DNA |
Q40464419 | Therapeutic spectrum in the treatment of myelodysplastic syndromes. |
Q37765469 | Therapy with azanucleosides for myelodysplastic syndromes |
Q40492466 | Tissue specificity and organisation of CpG methylation in calf satellite DNA I |
Q46044781 | Tissue-Specific Imprinting of the Mouse Insulin-Like Growth Factor II Receptor Gene Correlates with Differential Allele-Specific DNA Methylation |
Q36973783 | Topographical distribution of 5-methylcytosine in animal and plant DNA |
Q41966277 | Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation |
Q54551006 | Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. |
Q69098642 | Transcription of methylated viral DNA by eukaryotic RNA polymerase II |
Q58616504 | Transcriptional Landscape of PARs in Epithelial Malignancies |
Q28180053 | Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells |
Q36290263 | Transformation with DNA from 5-azacytidine-reactivated X chromosomes |
Q39511011 | Transforming genes and target cells of murine spleen focus-forming viruses |
Q35851931 | Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells |
Q46717074 | Trapped in action: direct visualization of DNA methyltransferase activity in living cells. |
Q37679466 | Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues |
Q37345034 | Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex |
Q37022672 | Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy. |
Q37079916 | Treatment strategies in myelodysplastic syndromes |
Q50089369 | Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas |
Q47568000 | Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads. |
Q54476622 | Tumor progression, oncogenes and the evolution of metastatic phenotypic diversity |
Q36655587 | Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer |
Q59087668 | Unborn Children (Protection) Bill |
Q34203924 | Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue |
Q39906678 | Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes |
Q35121110 | Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression |
Q36100100 | Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells |
Q35342673 | What do you mean, "epigenetic"? |
Q37962016 | Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors |
Q36894799 | X chromosome reactivation in mouse embryonal carcinoma cells |
Q27639568 | Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases |
Q80376979 | [DNA methylation on urinalysis and as a prognostic marker in urothelial cancer of the bladder] |
Q89862635 | [Research Progress of Epigenetics in Pathogenesis and Treatment of Malignant Tumors] |
Q36432360 | dNTP Supply Gene Expression Patterns after P53 Loss. |
Q36890276 | p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. |
Q36848202 | p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies |
Q39916396 | p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia |
Q72686110 | β-adrenergic receptor induction in HeLa cells: Synergistic effect of 5-azacytidine and butyrate |
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