Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma

scientific article published on 03 March 2020

Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S10038-020-0736-8
P698PubMed publication ID32127624

P50authorDebasmita Pankaj AloneQ90010169
P2093author name stringBiswajit Padhy
Bushra Hayat
Pranjya Paramita Mohanty
Ramani Shyam Kapuganti
P2860cites workRole of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.Q54197563
Multiplex Cytokine Analysis of Aqueous Humor in Eyes with Primary Open-Angle Glaucoma, Exfoliation Glaucoma, and CataractQ57669378
Pseudoexfoliation and Blood Flow AbnormalitiesQ62759840
Exfoliation syndromeQ73413239
Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucomaQ80138116
Promoter demethylation of Keap1 gene in human diabetic cataractous lensesQ84343395
Altered unfolded protein response and proteasome impairment in pseudoexfoliation pathogenesisQ91436771
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian developmentQ22010765
EUKARYOTIC CYTOSINE METHYLTRANSFERASESQ22255656
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxiaQ24315006
Phosphorylation of Kruppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation functionQ24680901
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profilesQ24700982
CpG islands in vertebrate genomesQ27861045
Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymesQ28292606
CpG islands and the regulation of transcriptionQ28315762
Molecular chaperones in protein folding and proteostasisQ29547715
Differential gene expression in pseudoexfoliation syndromeQ33224003
A novel CpG island set identifies tissue-specific methylation at developmental gene lociQ33317354
Exfoliation syndrome and occludable anglesQ34164185
Status of systemic oxidative stresses in patients with primary open-angle glaucoma and pseudoexfoliation syndromeQ34493810
Ocular and systemic pseudoexfoliation syndromeQ34522433
Hsp70 proteins in protein translocationQ34545609
Computational epigeneticsQ34715061
Natural history of open-angle glaucomaQ35009399
Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1.Q35742134
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylationQ35939534
Genome-wide methylation analysis demonstrates that 5-aza-2-deoxycytidine treatment does not cause random DNA demethylation in fragile X syndrome cells.Q36725163
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladderQ37730596
p300/CBP-associated factor (P/CAF) interacts with nuclear respiratory factor-1 to regulate the UDP-N-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyltransferase-3 geneQ38355171
Down-regulation and CpG island hypermethylation of CRYAA in age-related nuclear cataractQ39298160
LOXL1 Hypermethylation in Pseudoexfoliation Syndrome in the Uighur PopulationQ41391481
Trabecular meshwork in pseudoexfoliation syndrome with and without open-angle glaucoma. A morphometric, ultrastructural studyQ41679181
Cellular differentiation, cytidine analogs and DNA methylationQ42242732
Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells.Q46178288
Pseudoexfoliation and Alzheimer's associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expressionQ47707277
Anterior-chamber hypoxia and iris vasculopathy in pseudoexfoliation syndrome.Q53017491
P921main subjecthypermethylationQ106875739
P577publication date2020-03-03
P1433published inJournal of Human GeneticsQ6295302
P1476titleEpigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma

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