review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Moshe Szyf | |
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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain | Q22065852 | ||
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci | Q22254582 | ||
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Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2 | Q24301514 | ||
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex | Q24324026 | ||
UHRF1 plays a role in maintaining DNA methylation in mammalian cells | Q24336152 | ||
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Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood | Q24541484 | ||
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability | Q24544035 | ||
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An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens | Q24564335 | ||
Lasting epigenetic influence of early-life adversity on the BDNF gene | Q24600763 | ||
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse | Q24602512 | ||
Human DNA methylomes at base resolution show widespread epigenomic differences | Q24633677 | ||
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome | Q24647294 | ||
Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4 | Q24648201 | ||
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion | Q24650896 | ||
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation | Q24652480 | ||
Transposable elements: targets for early nutritional effects on epigenetic gene regulation | Q24681243 | ||
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development | Q24681489 | ||
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters | Q24682629 | ||
Antithetic effects of MBD2a on gene regulation | Q24684982 | ||
TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters | Q25255820 | ||
Broad epigenetic signature of maternal care in the brain of adult rats | Q27314001 | ||
Epigenetic programming by maternal behavior | Q27860466 | ||
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status | Q36288582 | ||
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells | Q36297565 | ||
Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine | Q36311707 | ||
Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes. | Q36315629 | ||
Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation | Q36579350 | ||
DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity | Q36726961 | ||
Metastable epialleles, imprinting, and the fetal origins of adult diseases | Q36783165 | ||
Complex disease, gender and epigenetics | Q36793656 | ||
The developmental origins of health and disease: current theories and epigenetic mechanisms. | Q36816569 | ||
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium | Q36872665 | ||
DNA methylation and systemic lupus erythematosus | Q36951024 | ||
Report on the IASO Stock Conference 2006: early and lifelong environmental epigenomic programming of metabolic syndrome, obesity and type II diabetes | Q36975977 | ||
Environmental epigenomics in human health and disease | Q37049211 | ||
A human B cell methylome at 100-base pair resolution | Q37052486 | ||
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. | Q37068711 | ||
Developmental origins of health and disease: new insights. | Q37069352 | ||
DNA methylation is a reversible biological signal | Q37197626 | ||
Towards a new developmental synthesis: adaptive developmental plasticity and human disease | Q37475772 | ||
Epigenetic mechanisms that underpin metabolic and cardiovascular diseases | Q37504694 | ||
Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle | Q37557036 | ||
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo. | Q38309516 | ||
CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower | Q38334537 | ||
Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis | Q38341003 | ||
Uteroplacental insufficiency alters DNA methylation, one-carbon metabolism, and histone acetylation in IUGR rats | Q38462433 | ||
Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors | Q39639196 | ||
Transient cyclical methylation of promoter DNA. | Q40005345 | ||
Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B. | Q40157240 | ||
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells | Q40166601 | ||
Gene body-specific methylation on the active X chromosome | Q40166744 | ||
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. | Q40176354 | ||
DNA methylation patterns. Formation and function | Q40186833 | ||
Role of T cell DNA methylation in lupus syndromes | Q40399385 | ||
DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells. | Q40580678 | ||
Role of promoter methylation in regulation of the mammalian heparanase gene | Q40621407 | ||
Valproate induces replication-independent active DNA demethylation | Q40647716 | ||
The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation | Q40690782 | ||
Demethylase activity is directed by histone acetylation | Q40783486 | ||
DNA demethylation and pericentromeric rearrangements of chromosome 1. | Q41087672 | ||
Induction of myogenic differentiation by an expression vector encoding the DNA methyltransferase cDNA sequence in the antisense orientation. | Q41126074 | ||
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet | Q41888615 | ||
High frequency mutagenesis by a DNA methyltransferase | Q41917002 | ||
Rapid appearance of hypomethylated DNA in livers of rats fed cancer-promoting, methyl-deficient diets | Q41956709 | ||
Cellular differentiation, cytidine analogs and DNA methylation | Q42242732 | ||
Epigenetic programming of the rRNA promoter by MBD3. | Q42412828 | ||
Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner | Q42846409 | ||
Enzyme-mediated cytosine deamination by the bacterial methyltransferase M.MspI. | Q42990671 | ||
Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing | Q43283756 | ||
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome | Q44086079 | ||
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process | Q44291577 | ||
The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine | Q44391318 | ||
Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance? | Q44543032 | ||
DNA methylation models histone acetylation | Q44585032 | ||
DNA methylation affects the formation of active chromatin | Q44614953 | ||
Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice | Q44768246 | ||
Parental imprinting of genes | Q45294626 | ||
N-methyl-D-aspartate 2b receptor subtype (NR2B) promoter methylation in patients during alcohol withdrawal | Q46059215 | ||
Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential | Q46581862 | ||
Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats | Q46726314 | ||
On the mechanism of demethylation of 5-methylcytosine in DNA. | Q46830714 | ||
Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats. | Q46870106 | ||
Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism | Q46931693 | ||
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. | Q48587952 | ||
Dnmt3L and the establishment of maternal genomic imprints | Q48874297 | ||
Genome-wide analysis of DNA methylation and gene expression changes in the mouse lung following subchronic arsenate exposure. | Q51550316 | ||
Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. | Q54551006 | ||
Substrate and sequence specificity of a eukaryotic DNA methylase | Q59062029 | ||
Canalization of Development and Genetic Assimilation of Acquired Characters | Q59065949 | ||
The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets | Q67505743 | ||
A 10-year perspective of motherless-mother monkey behavior | Q67525435 | ||
Effects of alcohol consumption on DNA methylation reactions and gene expression: implications for increased cancer risk | Q67968856 | ||
Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity | Q68092023 | ||
Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine | Q68949344 | ||
Effects of prolonged ethanol feeding on methionine metabolism in rat liver | Q69015074 | ||
Methylation of CpG sequences in eukaryotic DNA | Q70725576 | ||
Ras induces a general DNA demethylation activity in mouse embryonal P19 cells | Q72259850 | ||
Gene Regulation in Higher Cells | Q72537045 | ||
DNA methylation properties: consequences for pharmacology | Q72755740 | ||
Increased cytosine DNA-methyltransferase activity during colon cancer progression | Q72832112 | ||
Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat | Q73212017 | ||
The host defence function of genomic methylation patterns | Q74588154 | ||
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation | Q74608086 | ||
Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines | Q79716913 | ||
Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients | Q79953563 | ||
Using LUMA: a Luminometric-based assay for global DNA-methylation | Q81590977 | ||
Promoter-specific activation and demethylation by MBD2/demethylase | Q34144453 | ||
The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. | Q34180593 | ||
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer | Q34188991 | ||
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. | Q34249450 | ||
Occurrence of 5-methylcytosine in nucleic acids | Q34352684 | ||
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. | Q34469960 | ||
Assignment of candidate DNA methyltransferase gene (DNMT2) to human chromosome band 10p15.1 by in situ hybridization | Q34474330 | ||
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome | Q34508191 | ||
Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes | Q34570313 | ||
The role of DNA methylation in the central nervous system and neuropsychiatric disorders | Q34613653 | ||
Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5'-flanking region: a priming effect on the spreading of active demethylation. | Q34619602 | ||
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated | Q34624154 | ||
The social environment and the epigenome | Q34728015 | ||
DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
DNA methylation in cancer: too much, but also too little | Q34770545 | ||
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. | Q34854256 | ||
Valproic acid in pregnancy: how much are we endangering the embryo and fetus? | Q34984538 | ||
Distribution of 5-methylcytosine in chromatin | Q35034058 | ||
From epigenesis to epigenetics: the case of C. H. Waddington | Q35053504 | ||
Effects of vitamin B12 and folate deficiencies on DNA methylation and carcinogenesis in rat liver | Q35215615 | ||
An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis | Q35260743 | ||
HIDden targets of microRNAs for growth control | Q35296027 | ||
The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease | Q35571262 | ||
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation | Q35602033 | ||
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish | Q35616001 | ||
The concept of epigenetics and its role in the development of cardiovascular disease: commentary on "new and emerging theories of cardiovascular disease". | Q35798449 | ||
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2 | Q35848528 | ||
Variations in DNA methylation during mouse cell differentiation in vivo and in vitro | Q36256690 | ||
Trichostatin A causes selective loss of DNA methylation in Neurospora | Q36260468 | ||
P433 | issue | 2 | |
P921 | main subject | DNA methylation | Q874745 |
P304 | page(s) | 235-255 | |
P577 | publication date | 2011-02-04 | |
P1433 | published in | Toxicological Sciences | Q2446966 |
P1476 | title | The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylation | |
P478 | volume | 120 |
Q35853712 | A novel quantification method for the total demethylation potential of aquatic sample extracts from Bohai Bay using the EGFP reporter gene |
Q38971024 | Application of DNA adductomics to soil bacterium Sphingobium sp. strain KK22. |
Q63865887 | Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study |
Q36844184 | Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish development |
Q37967223 | Biological monitoring of carcinogens: current status and perspectives |
Q28384830 | Concern-driven integrated approaches to nanomaterial testing and assessment--report of the NanoSafety Cluster Working Group 10 |
Q39087129 | DNA methylation pyrosequencing assay is applicable for the assessment of epigenetic active environmental or clinical relevant chemicals. |
Q35647894 | DNA methylation topology: potential of a chromatin landmark for epigenetic drug toxicology |
Q28822387 | Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver |
Q36447333 | Diurnal expression of Dnmt3b mRNA in mouse liver is regulated by feeding and hepatic clockwork |
Q38137903 | Ecogenetics of mercury: from genetic polymorphisms and epigenetics to risk assessment and decision-making |
Q28388965 | Effects of methylmercury on epigenetic markers in three model species: mink, chicken and yellow perch |
Q26784562 | Environmental Impact on DNA Methylation in the Germline: State of the Art and Gaps of Knowledge |
Q34573062 | Epigenotoxicity of environmental pollutants evaluated by a combination of DNA methylation inhibition and capillary electrophoresis-laser-induced fluorescence immunoassay |
Q59217192 | Exposure to Perfluoroalkyl Substances and Sperm DNA Global Methylation in Arctic and European Populations |
Q28386421 | Hypomethylation of dual specificity phosphatase 22 promoter correlates with duration of service in firefighters and is inducible by low-dose benzo[a]pyrene |
Q38187459 | Impaired one carbon metabolism and DNA methylation in alcohol toxicity |
Q28730781 | Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra |
Q48324363 | Non-genetic transgenerational transmission of bipolar disorder: targeting DNA methyltransferases |
Q36543249 | Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain |
Q38872287 | The role of DNA methylation in the pathophysiology and treatment of bipolar disorder. |
Q38238589 | Zebrafish as a systems toxicology model for developmental neurotoxicity testing |