Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges

scientific article published on January 2016

Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1007/978-3-319-43624-1_1
P698PubMed publication ID27826832

P50authorRenata Z JurkowskaQ92305745
Albert JeltschQ30003285
P2860cites workSequence permutations in the molecular evolution of DNA methyltransferasesQ21045389
Circular Permutations in the Molecular Evolution of DNA MethyltransferasesQ21045391
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian developmentQ22010765
A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNAQ64441637
Cytosine methylation targetted to pre-determined sequencesQ73941543
Chemistry. How are alkynes scrambled?Q95780598
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brainQ22065852
Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1Q22299424
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1Q24316558
UHRF1 plays a role in maintaining DNA methylation in mammalian cellsQ24336152
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylationQ24338119
Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionineQ24562671
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strandsQ24562877
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineQ24614582
Genome-scale DNA methylation maps of pluripotent and differentiated cellsQ24621431
High sensitivity mapping of methylated cytosinesQ24630600
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNAQ24632387
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNAQ24645346
The cancer epigenome: its origins, contributions to tumorigenesis, and translational implicationsQ26828751
Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analogQ27629529
Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA MethylationQ27666325
A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stabilityQ27666366
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA MethylationQ27677188
Structural insight into autoinhibition and histone H3-induced activation of DNMT3AQ27696162
HhaI methyltransferase flips its target base out of the DNA helixQ27731553
Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionineQ27731970
Targeted mutation of the DNA methyltransferase gene results in embryonic lethalityQ28131773
DNA Methylation and Gene FunctionQ28263722
Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylasesQ28273541
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferasesQ28507226
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprintingQ28508038
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3LQ28585211
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNAQ28589108
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cellsQ29399636
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterningQ29615977
Highly integrated single-base resolution maps of the epigenome in ArabidopsisQ29616098
SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase foldQ29618153
Hypomethylation distinguishes genes of some human cancers from their normal counterpartsQ29619217
Type II restriction endonucleases--a historical perspective and moreQ33843093
Direct detection of DNA methylation during single-molecule, real-time sequencingQ33888756
X inactivation, differentiation, and DNA methylationQ33999850
The discovery of 5-formylcytosine in embryonic stem cell DNA.Q34027511
DNA methylation in bacteria: from the methyl group to the methylomeQ34043592
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylationQ34074317
DNA modification and restrictionQ34221874
DNA restriction and modification mechanisms in bacteriaQ34224398
Host specificity of DNA produced by Escherichia coli. I. Host controlled modification of bacteriophage lambdaQ34251434
DNA methylation and the frequency of CpG in animal DNA.Q34252001
5-Methylcytosine in eukaryotic DNA.Q34252459
Targeting DNA methylation for epigenetic therapyQ34258037
Cytosine modification in DNA by BcnI methylase yields N4-methylcytosineQ34272641
THE ENZYMATIC METHYLATION OF RNA AND DNA. 8. EFFECTS OF BACTERIOPHAGE INFECTION ON THE ACTIVITY OF THE METHYLATING ENZYMESQ34409680
THE ENZYMATIC METHYLATION OF RNA AND DNA, II. ON THE SPECIES SPECIFICITY OF THE METHYLATION ENZYMES.Q34427839
Recognition and cleavage of DNA by type-II restriction endonucleasesQ34431350
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastomaQ34453650
Cytosine-specific type II DNA methyltransferases. A conserved enzyme core with variable target-recognizing domainsQ34525794
Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferasesQ34587622
5-Hydroxymethylcytosine: a stable or transient DNA modification?Q34616176
Array-based genomic resequencing of human leukemiaQ34618836
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)Q35021851
The 5-methylcytosine content of DNA from human tumorsQ35689206
Sequence-specific recognition of double helical nucleic acids by proteinsQ35987597
Restriction and modification systemsQ37041891
Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferaseQ37168010
The colorful history of active DNA demethylation.Q37201774
Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosineQ37576837
Structure and function of mammalian DNA methyltransferases.Q37829700
DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studiesQ38049175
Oxygen, epigenetic signaling, and the evolution of early lifeQ38085926
DNA methylation dynamics in health and diseaseQ38086773
New concepts in DNA methylationQ38221707
Genetic alterations of DNA methylation machinery in human diseasesQ38459846
Epigenome Editing: State of the Art, Concepts, and PerspectivesQ38687451
Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.Q38971249
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replicationQ39098794
Restriction and Modification of DNAQ39919645
On base flippingQ40442261
Predictive motifs derived from cytosine methyltransferasesQ40448394
Structure and Function of DNA MethyltransferasesQ40475987
The sequence specificity of a mammalian DNA methylaseQ40575369
The DNA and S-adenosylmethionine-binding regions of EcoDam and related methyltransferasesQ41377968
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tailQ41965881
Cellular differentiation, cytidine analogs and DNA methylationQ42242732
Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymesQ42605575
Quantification of the sixth DNA base hydroxymethylcytosine in the brainQ43003710
The cytosine N4-methyltransferase M.PvuII also modifies adenine residuesQ43639216
Man-made cell-like compartments for molecular evolutionQ47857062
Structure-guided analysis reveals nine sequence motifs conserved among DNA amino-methyltransferases, and suggests a catalytic mechanism for these enzymesQ48069333
Dnmt3L and the establishment of maternal genomic imprintsQ48874297
Universal catalytic domain structure of AdoMet-dependent methyltransferases.Q53012595
The GATATC-modification enzyme EcoRV is closely related to the GATC-recognizing methyltransferases DpnII and dam from E. coli and phage T4.Q54762518
Occurrence of a new base in the deoxyribonucleic acid of a strain of Bacterium coli.Q55036971
BASE FLIPPINGQ56256582
Alternative chromatin structure at CpG islandsQ57259142
On the Substrate Specificity of DNA MethyltransferasesQ57267693
Substrate and sequence specificity of a eukaryotic DNA methylaseQ59062029
Sequence specificity of methylation in higher plant DNAQ59066718
Cloning the modification methylase gene of Bacillus sphaericus R in Escherichia coliQ60505834
P407language of work or nameEnglishQ1860
P921main subjectDNA methylationQ874745
P304page(s)1-17
P577publication date2016-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titleMechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges
P478volume945

Reverse relations

cites work (P2860)
Q47616651Association of DNMT3b gene variants with sporadic Parkinson's disease in a Chinese Han population
Q55023866Circularly permuted variants of two CG-specific prokaryotic DNA methyltransferases.
Q50422488DNA Methylation Dynamics of Genomic Imprinting in Mouse Development.
Q92316555Editorial-Role of DNA Methyltransferases in the Epigenome
Q38742430Epigenetics and allergy: from basic mechanisms to clinical applications.
Q57056824Methylation-Induced Hypermutation in Natural Populations of Bacteria
Q57184273Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA
Q91287194The bacterial epigenome
Q64099722The emerging role of epigenetics in human autoimmune disorders
Q89999474gga-miR-27b-3p enhances type I interferon expression and suppresses infectious bursal disease virus replication via targeting cellular suppressors of cytokine signaling 3 and 6 (SOCS3 and 6)

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