review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1146/ANNUREV.BB.24.060195.001453 |
P953 | full work available at URL | http://www.annualreviews.org/doi/pdf/10.1146/annurev.bb.24.060195.001453 |
P698 | PubMed publication ID | 7663118 |
P2093 | author name string | X. Cheng | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 293-318 | |
P577 | publication date | 1995-01-01 | |
P1433 | published in | Annual Review of Biophysics and Biomolecular Structure | Q26853798 |
P1476 | title | Structure and Function of DNA Methyltransferases | |
P478 | volume | 24 |
Q64052771 | 6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda |
Q35974019 | A cell cycle-regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA |
Q33938784 | A dual role for substrate S-adenosyl-L-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase |
Q52353488 | A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA. |
Q30552760 | Aberrant regulation of DNA methylation in amyotrophic lateral sclerosis: a new target of disease mechanisms |
Q36564912 | Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides |
Q35867541 | Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification |
Q33354085 | An integrated epigenetic and genetic analysis of DNA methyltransferase genes (DNMTs) in tumor resistant and susceptible chicken lines |
Q34617210 | Arabidopsis MET1 cytosine methyltransferase mutants |
Q56256582 | BASE FLIPPING |
Q39003514 | Bacterial DNA Methylation and Methylomes |
Q33721124 | Bacterial DNA methylation: a cell cycle regulator? |
Q44261818 | Bacteriophage T4 Dam DNA-(N6-adenine)-methyltransferase. Processivity and orientation to the methylation target |
Q44534317 | Bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase): evidence for two distinct stages of methylation under single turnover conditions |
Q41112950 | Base eversion and shuffling by DNA methyltransferases |
Q34587622 | Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases |
Q38312858 | Biotin-avidin microplate assay for the quantitative analysis of enzymatic methylation of DNA by DNA methyltransferases |
Q102145628 | Caloric restriction upregulates the expression of DNMT3.1, lacking the conserved catalytic domain, in Daphnia magna |
Q44466061 | Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme |
Q39752537 | Changing the recognition specificity of a DNA-methyltransferase by in vitro evolution |
Q39096547 | Changing the target base specificity of the EcoRV DNA methyltransferase by rational de novo protein-design |
Q35361388 | Characterization of LlaKI, a New Metal Ion-Independent Restriction Endonuclease from Lactococcus lactis KLDS4. |
Q41311755 | Chemistry and biology of DNA methyltransferases |
Q58794852 | Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2 |
Q33585828 | Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases |
Q42675636 | Complete genome sequence of ΦMH1, a Leuconostoc temperate phage |
Q35702821 | Conserved plant genes with similarity to mammalian de novo DNA methyltransferases. |
Q47755068 | Conserved sequence motifs in plant S-adenosyl-L-methionine-dependent methyltransferases |
Q27641504 | Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain |
Q40024302 | Cyclopropane ring formation in membrane lipids of bacteria. |
Q34803437 | Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes. |
Q39003551 | DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications |
Q46681715 | DNA interaction of the CcrM DNA methyltransferase: a mutational and modeling study |
Q41730013 | DNA methylation as a target for drug design |
Q34819430 | DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis |
Q57523851 | DNA methylation maintenance consolidates RNA-directed DNA methylation and transcriptional gene silencing over generations inArabidopsis thaliana |
Q58867784 | DNA methylation: A promising target for the twenty-first century |
Q43184131 | DNA methyltransferase 1 mutations and mitochondrial pathology: is mtDNA methylated? |
Q40388507 | DNA of Drosophila melanogaster contains 5-methylcytosine |
Q38346263 | Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates |
Q58090964 | Determination of the presence of 5-methylcytosine in Paramecium tetraurelia |
Q57267577 | Discovery of Novel and Selective DNA Methyltransferase 1 Inhibitors by Pharmacophore and Docking-Based Virtual Screening |
Q37698622 | Diversity of DNA methyltransferases that recognize asymmetric target sequences |
Q34154656 | Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA. |
Q64039305 | Effect of Disease-Associated Germline Mutations on Structure Function Relationship of DNA Methyltransferases |
Q45761550 | Enzymes that keep DNA under control: Meeting: DNA enzymes: structures and mechanisms |
Q44403618 | Enzymology of Methylation of Tea Catechins and Inhibition of Catechol-O-methyltransferase by (−)-Epigallocatechin Gallate |
Q34575845 | Epigenetic regulation during fetal femur development: DNA methylation matters. |
Q35614360 | Epigenetic regulation of motor neuron cell death through DNA methylation |
Q93067858 | Epigenomic plasticity of Arabidopsis msh1 mutants under prolonged cold stress |
Q24548949 | Escherichia coli TehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance |
Q63979918 | Eukaryotic 5-methylcytosine (m⁵C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease |
Q34706101 | Exposition of a family of RNA m(5)C methyltransferases from searching genomic and proteomic sequences |
Q38336594 | Functional mapping of the EcoRV DNA methyltransferase by random mutagenesis and screening for catalytically inactive mutants |
Q47892200 | Functional roles of conserved amino acid residues in DNA methyltransferases investigated by site-directed mutagenesis of the EcoRV adenine-N6-methyltransferase |
Q34414767 | Gardening the genome: DNA methylation in Arabidopsis thaliana |
Q41971328 | Genetic evidence that DNA methyltransferase DRM2 has a direct catalytic role in RNA-directed DNA methylation in Arabidopsis thaliana. |
Q35076840 | Genome sequence of Ostreococcus tauri virus OtV-2 throws light on the role of picoeukaryote niche separation in the ocean. |
Q92709352 | Genome-wide systematic identification of methyltransferase recognition and modification patterns |
Q38172016 | Genomic imprinting--the struggle of the genders at the molecular level |
Q33742805 | HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference |
Q39429368 | Highly Iterated Palindromic Sequences (HIPs) and Their Relationship to DNA Methyltransferases |
Q44548818 | Identification and mutational analysis of Mg2+ binding site in EcoP15I DNA methyltransferase: involvement in target base eversion |
Q30360372 | Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological Roles. |
Q52895607 | Identification of differentially expressed proteins in ruminal epithelium in response to a concentrate-supplemented diet. |
Q34107699 | Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens |
Q43559827 | Identification of the active oligomeric state of an essential adenine DNA methyltransferase from Caulobacter crescentus |
Q38324707 | Identification of the binding site for the extrahelical target base in N6-adenine DNA methyltransferases by photo-cross-linking with duplex oligodeoxyribonucleotides containing 5-iodouracil at the target position |
Q33996334 | Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components |
Q48124347 | Interactions of (-)-ilimaquinone with methylation enzymes: implications for vesicular-mediated secretion |
Q91806479 | KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells |
Q44625634 | Maintenance of species identity and controlling speciation of bacteria: a new function for restriction/modification systems? |
Q57167095 | Mammalian DNA methyltransferases: new discoveries and open questions |
Q38845904 | Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation. |
Q38797211 | Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges |
Q45117060 | Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase |
Q30524877 | Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery |
Q33876474 | Metadynamics simulation study on the conformational transformation of HhaI methyltransferase: an induced-fit base-flipping hypothesis |
Q38435392 | Methylation of zebularine: a quantum mechanical study incorporating interactive 3D pdf graphs. |
Q39036341 | Methyltransferase-Directed Labeling of Biomolecules and its Applications. |
Q42257937 | Methyltransferase-directed covalent coupling of fluorophores to DNA. |
Q37413126 | Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS. |
Q28587647 | Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases |
Q27931953 | Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme |
Q39615998 | Mutational analysis of conserved residues in HhaI DNA methyltransferase |
Q36401376 | N6-methyl-adenine: an epigenetic signal for DNA-protein interactions |
Q24816614 | Natural history of S-adenosylmethionine-binding proteins |
Q38895570 | New hope: the emerging role of 5-hydroxymethylcytosine in mental health and disease. |
Q46007576 | Nucleotide excision repair eliminates unique DNA-protein cross-links from mammalian cells. |
Q57267693 | On the Substrate Specificity of DNA Methyltransferases |
Q34091253 | On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2. |
Q51664000 | P087, a lactococcal phage with a morphogenesis module similar to an Enterococcus faecalis prophage. |
Q77195407 | Probing the role of cysteine residues in the EcoP15I DNA methyltransferase |
Q37737507 | RNA-directed DNA methylation: mechanisms and functions |
Q57267635 | Reading and writing DNA methylation |
Q38318722 | Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna. |
Q46680798 | Regulation of traJ transcription in the Salmonella virulence plasmid by strand-specific DNA adenine hemimethylation. |
Q37108058 | Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB |
Q41707983 | Repeat-Induced Point Mutation and Other Genome Defense Mechanisms in Fungi |
Q45259074 | Residues distal from the active site that alter enzyme function in M.HhaI DNA cytosine methyltransferase. |
Q33993566 | Role and mechanism of action of C. PvuII, a regulatory protein conserved among restriction-modification systems |
Q38298515 | Role of DNA minor groove interactions in substrate recognition by the M.SinI and M.EcoRII DNA (cytosine-5) methyltransferases |
Q42793465 | S-adenosylmethionine-binding properties of a bacterial phospholipid N-methyltransferase. |
Q24804472 | Segmentally variable genes: a new perspective on adaptation |
Q33725310 | Sequence analysis of Leuconostoc mesenteroides bacteriophage Phi1-A4 isolated from an industrial vegetable fermentation. |
Q42606517 | Sequence analysis of the Lactobacillus temperate phage Sha1. |
Q35813616 | Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes |
Q37961630 | Single-molecule analysis using DNA origami. |
Q38037622 | Single-molecule, genome-scale analyses of DNA modifications: exposing the epigenome with next-generation technologies |
Q38308094 | Specificity of DNA binding and methylation by the M.FokI DNA methyltransferase |
Q27930248 | Spermidine biosynthesis in Saccharomyces cerevisae: polyamine requirement of a null mutant of the SPE3 gene (spermidine synthase). |
Q27933658 | Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant |
Q36782104 | Structural ensemble and microscopic elasticity of freely diffusing DNA by direct measurement of fluctuations |
Q37829700 | Structure and function of mammalian DNA methyltransferases. |
Q56256578 | Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure |
Q27627400 | Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases |
Q36598928 | Structure, function and mechanism of exocyclic DNA methyltransferases |
Q27641578 | Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii |
Q39721172 | Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, BcgI. |
Q35900625 | Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates |
Q37346268 | Symmetry elements in DNA structure important for recognition/methylation by DNA [amino]-methyltransferases |
Q27732664 | The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends |
Q35978195 | The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond |
Q37934241 | The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner. |
Q34344734 | The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites |
Q38287903 | The Escherichia coli dam DNA methyltransferase modifies DNA in a highly processive reaction |
Q50872303 | The M.EcoRV DNA-(adenine N6)-methyltransferase uses DNA bending for recognition of an expanded EcoDam recognition site. |
Q91287194 | The bacterial epigenome |
Q90639977 | The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site |
Q43409472 | The coupling of tight DNA binding and base flipping: identification of a conserved structural motif in base flipping enzymes |
Q43639216 | The cytosine N4-methyltransferase M.PvuII also modifies adenine residues |
Q34204135 | The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity. |
Q39029674 | The integration of epigenetics and genetics in nutrition research for CVD risk factors. |
Q43091873 | The preventive efficacy of methylcobalamin on rat peripheral neuropathy influenced by diabetes via neural IGF-1 levels |
Q85398165 | Theoretical study on the binding mechanism between N6-methyladenine and natural DNA bases |
Q26865951 | To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems |
Q40623261 | Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts |
Q27645184 | Two alternative conformations of S-adenosyl-L-homocysteine bound to Escherichia coli DNA adenine methyltransferase and the implication of conformational changes in regulating the catalytic cycle |
Q24548508 | Type I restriction systems: sophisticated molecular machines (a legacy of Bertani and Weigle) |
Q38298030 | Use of DNA molecules substituted with unnatural nucleotides to probe specific drug-DNA interactions |
Q38294318 | Water-assisted dual mode cofactor recognition by HhaI DNA methyltransferase. |
Q27639568 | Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases |
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Q37220025 | m5C RNA and m5C DNA methyl transferases use different cysteine residues as catalysts |
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