| scholarly article | Q13442814 |
| P50 | author | Iain William Mattaj | Q21127249 |
| Karsten Weis | Q37375543 | ||
| P2093 | author name string | A I Lamond | |
| P433 | issue | 5213 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Karyopherin subunit alpha 1 | Q21111455 |
| Karyopherin subunit alpha 2 | Q21131854 | ||
| P304 | page(s) | 1049-1053 | |
| P577 | publication date | 1995-05-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences | |
| P478 | volume | 268 |
| Q24563147 | A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus |
| Q36236901 | A GTPase distinct from Ran is involved in nuclear protein import |
| Q27670487 | A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin α1 |
| Q73485988 | A Nuclear Localization Signal of Human Aryl Hydrocarbon Receptor Nuclear Translocator/Hypoxia-inducible Factor 1β Is a Novel Bipartite Type Recognized by the Two Components of Nuclear Pore-targeting Complex |
| Q36949191 | A T42A Ran mutation: differential interactions with effectors and regulators, and defect in nuclear protein import |
| Q36570198 | A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity |
| Q27929963 | A distinct nuclear import pathway used by ribosomal proteins |
| Q42646147 | A gamma-2 herpesvirus nucleocytoplasmic shuttle protein interacts with importin alpha 1 and alpha 5. |
| Q28138319 | A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins |
| Q24550602 | A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway |
| Q24316050 | A novel class of RanGTP binding proteins |
| Q24324050 | A novel receptor-mediated nuclear protein import pathway |
| Q24310068 | A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex |
| Q24322859 | A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export |
| Q36273988 | A nuclear export signal in Kap95p is required for both recycling the import factor and interaction with the nucleoporin GLFG repeat regions of Nup116p and Nup100p |
| Q24309825 | A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway |
| Q40965861 | A test of the cytosolic apolipoprotein E hypothesis fails to detect the escape of apolipoprotein E from the endocytic pathway into the cytosol and shows that direct expression of apolipoprotein E in the cytosol is cytotoxic. |
| Q24290214 | ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli |
| Q87404844 | Aberrant expression of nuclear KPNA2 is correlated with early recurrence and poor prognosis in patients with small hepatocellular carcinoma after hepatectomy |
| Q24670400 | An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins |
| Q28246489 | Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97 |
| Q28140613 | BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence |
| Q28379514 | CNI-H0294, a nuclear importation inhibitor of the human immunodeficiency virus type 1 genome, abrogates virus replication in infected activated peripheral blood mononuclear cells. |
| Q24597818 | Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-alpha |
| Q36255858 | Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways |
| Q40756616 | Characterization of an unusual importin alpha binding motif in the borna disease virus p10 protein that directs nuclear import |
| Q24312861 | Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus |
| Q38795769 | Characterization of specific antigenic epitopes and the nuclear export signal of the Porcine circovirus 2 ORF3 protein |
| Q40758360 | Characterization of the nuclear export signal of polypyrimidine tract-binding protein |
| Q43559471 | Characterization of the nuclear import pathway for HIV-1 integrase. |
| Q41079130 | Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities |
| Q24321853 | Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor |
| Q24680128 | Cloning and characterization of human karyopherin beta3 |
| Q24324633 | Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL |
| Q24311981 | Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family |
| Q39646499 | Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways |
| Q24803042 | Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties |
| Q24536213 | Cross-talk between snurportin1 subdomains |
| Q27764929 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha |
| Q27622027 | Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha |
| Q35846362 | Cytoplasmic retention and nuclear import of 5S ribosomal RNA containing RNPs. |
| Q41099632 | Cytoskeleton-membrane interactions |
| Q24682912 | Determination of the functional domain organization of the importin alpha nuclear import factor |
| Q28304373 | Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97 |
| Q24522609 | Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1 |
| Q37382182 | Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts. |
| Q49486091 | Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import |
| Q39610808 | Discrimination between NL1- and NL2-mediated nuclear localization of the glucocorticoid receptor |
| Q34045683 | Dissection of a novel nuclear localization signal in open reading frame 29 of varicella-zoster virus |
| Q29620112 | Distinct functions for the two importin subunits in nuclear protein import |
| Q35511186 | Diversification of importin-α isoforms in cellular trafficking and disease states |
| Q24532120 | Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex |
| Q36315139 | Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. |
| Q48955413 | Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei |
| Q37582945 | Evasion of interferon responses by Ebola and Marburg viruses |
| Q29620231 | Evidence for a role of CRM1 in signal-mediated nuclear protein export |
| Q24554392 | Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import |
| Q38361181 | Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor. |
| Q41150735 | Exogenously injected nuclear import factor p10/NTF2 inhibits signal-mediated nuclear import and export of proteins in living cells |
| Q24316152 | Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor |
| Q36686502 | Expression in yeast of binding regions of karyopherins alpha and beta inhibits nuclear import and cell growth |
| Q34065588 | Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1 |
| Q24522554 | Functional conservation of the transportin nuclear import pathway in divergent organisms |
| Q34669894 | Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore |
| Q24318249 | Functional proteomic analysis of human nucleolus |
| Q27933501 | GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function |
| Q36685432 | GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import |
| Q48301884 | Genomic organization and chromosomal localization of the importin alpha1 gene in the mouse |
| Q39578229 | Hepatitis delta antigen mediates the nuclear import of hepatitis delta virus RNA. |
| Q42062218 | Human proliferation-related protein p120 interacts with HSRP1 |
| Q27938119 | Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein |
| Q24316440 | Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs |
| Q27933981 | Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast |
| Q37385861 | Identification of a selective nuclear import signal in adenosine deaminases acting on RNA. |
| Q24561933 | Identification of different roles for RanGDP and RanGTP in nuclear protein import |
| Q48042494 | Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression |
| Q37319145 | Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation |
| Q36371862 | Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. |
| Q74236761 | Importin alpha binds to an unusual bipartite nuclear localization signal in the heterogeneous ribonucleoprotein type I |
| Q24322708 | Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication |
| Q48059143 | Importin provides a link between nuclear protein import and U snRNA export |
| Q24613093 | Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme |
| Q42716697 | Importin-alpha promotes passage through the nuclear pore complex of human immunodeficiency virus type 1 Vpr. |
| Q24805778 | Importin-beta-like nuclear transport receptors |
| Q37661564 | Importins and exportins regulating allergic immune responses |
| Q40968433 | Importins/karyopherins meet nucleoporins |
| Q39716299 | In vitro and in vivo evidence that protein and U1 snRNP nuclear import in somatic cells differ in their requirement for GTP-hydrolysis, Ran/TC4 and RCC1 |
| Q40243200 | In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p |
| Q40418394 | In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity |
| Q24300253 | Inhibition of nuclear import by the proapoptotic protein CC3 |
| Q53783735 | Interaction of Sp1 zinc finger with transport factor in the nuclear localization of transcription factor Sp1 |
| Q24314389 | Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta |
| Q27937378 | Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase |
| Q53408911 | KPNA2 interacts with P65 to modulate catabolic events in osteoarthritis. |
| Q37148209 | KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a |
| Q58773791 | KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc |
| Q73041162 | Kap104p-mediated nuclear import. Nuclear localization signals in mRNA-binding proteins and the role of Ran and Rna |
| Q27932702 | Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins |
| Q24319692 | Karyopherin beta2 mediates nuclear import of a mRNA binding protein |
| Q44182771 | Localization of importin alpha (Rch1) at the plasma membrane and subcellular redistribution during lymphocyte activation |
| Q24291539 | MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein |
| Q46861497 | Mechanism of the stress-induced collapse of the Ran distribution |
| Q34638038 | Molecular and clinical studies in 138 Japanese patients with Silver-Russell syndrome |
| Q24671748 | Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins |
| Q27649519 | Molecular basis for the recognition of snurportin 1 by importin beta |
| Q37743200 | Molecular determinants for subcellular localization of hepatitis C virus core protein |
| Q24651426 | Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus |
| Q27938007 | Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p. |
| Q28217732 | Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import |
| Q24293315 | Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways |
| Q77903798 | Nuclear import and export of proteins: the molecular basis for intracellular signaling |
| Q28144264 | Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8) |
| Q57973315 | Nuclear import factors importin α and importin β undergo mutually induced conformational changes upon association |
| Q48061619 | Nuclear import in permeabilized protoplasts from higher plants has unique features |
| Q42632635 | Nuclear import of U snRNPs requires importin beta |
| Q27930252 | Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast |
| Q35784874 | Nuclear import of bovine papillomavirus type 1 E1 protein is mediated by multiple alpha importins and is negatively regulated by phosphorylation near a nuclear localization signal |
| Q27865295 | Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import |
| Q35428699 | Nuclear import of plasmid DNA in digitonin-permeabilized cells requires both cytoplasmic factors and specific DNA sequences |
| Q40762719 | Nuclear import of polypeptides, polynucleotides and supramolecular complexes |
| Q24647758 | Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip |
| Q24670107 | Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms |
| Q24294995 | Nuclear import strategies of high risk HPV16 L1 major capsid protein |
| Q40274100 | Nuclear import strategies of high-risk HPV18 L2 minor capsid protein. |
| Q28260234 | Nuclear localization and export signals of the human aryl hydrocarbon receptor |
| Q33786457 | Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences |
| Q28189725 | Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha) |
| Q39127789 | Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates |
| Q36593332 | Nuclear localization signal binding protein from Arabidopsis mediates nuclear import of Agrobacterium VirD2 protein |
| Q28645531 | Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin |
| Q34426767 | Nuclear protein import |
| Q24617416 | Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta |
| Q27864127 | Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes |
| Q88633439 | Nuclear transport adapts to varying heat stress in a multistep mechanism |
| Q36273838 | Nucleocytoplasmic recycling of the nuclear localization signal receptor alpha subunit in vivo is dependent on a nuclear export signal, energy, and RCC1 |
| Q40403309 | Nucleocytoplasmic transport: factors and mechanisms |
| Q29547904 | Nucleocytoplasmic transport: signals, mechanisms and regulation |
| Q37432537 | Nucleotide-specific interaction of Ran/TC4 with nuclear transport factors NTF2 and p97. |
| Q27933375 | Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex |
| Q27931388 | Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha |
| Q24524071 | Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis |
| Q49019414 | Partial purification and characterization of a protein kinase that is activated by nuclear localization signal peptides |
| Q30428130 | Phosphorylation of Srp1p, the yeast nuclear localization signal receptor, in vitro and in vivo |
| Q35208788 | Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. |
| Q36933885 | Possible role for cellular karyopherins in regulating polyomavirus and papillomavirus capsid assembly |
| Q28131733 | Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins |
| Q41017143 | Protein import into the nucleus |
| Q47658168 | Protein interactions involved in nuclear import of the Agrobacterium VirE2 protein in vivo and in vitro. |
| Q42772140 | RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus |
| Q71973464 | Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta |
| Q77696853 | Ran-dependent signal-mediated nuclear import does not require GTP hydrolysis by Ran |
| Q41075696 | Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex |
| Q36237637 | RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import |
| Q30304464 | RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3. |
| Q24644181 | RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153 |
| Q57378150 | Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis |
| Q35680376 | Reconstitution of nuclear import in permeabilized cells |
| Q30309361 | Regulation of nuclear import and export by the GTPase Ran. |
| Q22254241 | Relationship between contact inhibition and intranuclear S100C of normal human fibroblasts |
| Q34033155 | Rev protein and its cellular partners |
| Q24537505 | Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11 |
| Q33440177 | Role of importin alpha8, a new member of the importin alpha family of nuclear transport proteins, in early embryonic development in cattle |
| Q24684268 | Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import |
| Q48064951 | Role of the nuclear transport factor p10 in nuclear import |
| Q35857537 | Role of the sonchus yellow net virus N protein in formation of nuclear viroplasms |
| Q29616137 | Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts |
| Q88616666 | Septin 9 isoform 1 (SEPT9_i1) specifically interacts with importin-α7 to drive hypoxia-inducible factor (HIF)-1α nuclear translocation |
| Q24316296 | Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure |
| Q34064096 | Structure and function correlation in histone H2A peptide-mediated gene transfer. |
| Q27618407 | Structure of importin-beta bound to the IBB domain of importin-alpha |
| Q36466624 | Sumoylation of SAE2 C terminus regulates SAE nuclear localization |
| Q48403962 | TIP30 inhibits oligodendrocyte precursor cell differentiation via cytoplasmic sequestration of Olig1. |
| Q75294239 | Taking from the cytoplasm and giving to the pore: soluble transport factors in nuclear protein import |
| Q39591808 | The C-terminal proline-rich tail of human immunodeficiency virus type 2 Vpx is necessary for nuclear localization of the viral preintegration complex in nondividing cells |
| Q47319905 | The E7 oncoprotein of high-risk human papillomavirus type 16 enters the nucleus via a nonclassical Ran-dependent pathway |
| Q27931303 | The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor |
| Q34181827 | The L1 major capsid protein of human papillomavirus type 11 interacts with Kap beta2 and Kap beta3 nuclear import receptors |
| Q27867699 | The NPI-1/NPI-3 (karyopherin alpha) binding site on the influenza a virus nucleoprotein NP is a nonconventional nuclear localization signal |
| Q24612205 | The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence |
| Q37452474 | The bovine immunodeficiency virus rev protein: identification of a novel lentiviral bipartite nuclear localization signal harboring an atypical spacer sequence |
| Q24563136 | The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import |
| Q38069877 | The functional role of the novel biomarker karyopherin α 2 (KPNA2) in cancer |
| Q41889373 | The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro |
| Q24309388 | The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors |
| Q33896394 | The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip |
| Q34410413 | The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor |
| Q28278924 | The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins |
| Q24641817 | The nucleoporin nup153 plays a critical role in multiple types of nuclear export |
| Q37683446 | The positively charged termini of L2 minor capsid protein required for bovine papillomavirus infection function separately in nuclear import and DNA binding |
| Q41066972 | Toward the molecular dissection of protein import into nuclei |
| Q44624422 | Translocation of β-catenin into the nucleus independent of interactions with FG-rich nucleoporins |
| Q29615611 | Transport into and out of the nucleus |
| Q24312051 | Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins |
| Q33666869 | Turn up the HEAT. |
| Q29619290 | Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p |
| Q40976098 | Up-regulation of nuclear protein import by nuclear localization signal sequences in living cells. |
| Q39741142 | Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function |
| Q24533072 | Viral protein R regulates nuclear import of the HIV-1 pre-integration complex |
| Q38148317 | Viruses challenge selectivity barrier of nuclear pores |
| Q28640339 | beta-catenin can be transported into the nucleus in a Ran-unassisted manner |
| Q28583227 | cDNA cloning and analysis of the expression of nucleoporin p45 |
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