| scholarly article | Q13442814 |
| P2093 | author name string | Ji-Joon Song | |
| Robert E Kingston | |||
| P2860 | cites work | Crystal structure of the nucleosome core particle at 2.8 A resolution | Q22122355 |
| Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression | Q24297027 | ||
| Structural basis for molecular recognition and presentation of histone H3 by WDR5 | Q24301311 | ||
| Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 | Q24314963 | ||
| Structural basis of histone H4 recognition by p55 | Q27650473 | ||
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development | Q29614526 | ||
| Mechanisms of transcriptional memory | Q34271573 | ||
| Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Q34546055 | ||
| Molecular recognition of histone H3 by the WD40 protein WDR5. | Q34546063 | ||
| Chromatin remodeling and cancer, Part I: Covalent histone modifications | Q34682092 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| leukemia | Q29496 | ||
| methylated histone binding | Q14911714 | ||
| WD repeat domain 5 | Q21171851 | ||
| binding pocket | Q61659196 | ||
| P304 | page(s) | 35258-64 | |
| P577 | publication date | 2008-12-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket | |
| P478 | volume | 283 |
| Q38989732 | A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia. |
| Q38756663 | A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks |
| Q33789775 | A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes |
| Q27342739 | A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line |
| Q38307367 | A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer |
| Q34531263 | ATX1-generated H3K4me3 is required for efficient elongation of transcription, not initiation, at ATX1-regulated genes |
| Q33761102 | An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain |
| Q38772574 | An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5. |
| Q42216959 | Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction |
| Q59808041 | Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex |
| Q42141777 | Assembling a COMPASS. |
| Q37459333 | Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation |
| Q27665361 | Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2) |
| Q35172965 | Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation |
| Q50425734 | CHARGE and Kabuki syndromes: a phenotypic and molecular link. |
| Q27664073 | Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1 |
| Q35710023 | Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression |
| Q42365675 | Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia |
| Q47249522 | Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction |
| Q57773815 | Discovery of Potent 2-Aryl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design |
| Q39147680 | Diverse roles of WDR5-RbBP5-ASH2L-DPY30 (WRAD) complex in the functions of the SET1 histone methyltransferase family |
| Q33884352 | Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon |
| Q57266571 | Facile target validation in an animal model with intracellularly expressed monobodies |
| Q27683539 | High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction |
| Q27006839 | Hijacked in cancer: the KMT2 (MLL) family of methyltransferases |
| Q37469434 | Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes |
| Q58830255 | Histone Recognition by WD40 Proteins |
| Q30635246 | IMAAAGINE: a webserver for searching hypothetical 3D amino acid side chain arrangements in the Protein Data Bank |
| Q34391209 | Identifying the hotspots on the top faces of WD40-repeat proteins from their primary sequences by β-bulges and DHSW tetrads |
| Q42182620 | Interaction of SET domains with histones and nucleic acid structures in active chromatin. |
| Q34336457 | Keeping it in the family: diverse histone recognition by conserved structural folds |
| Q37857936 | MLL1/WDR5 complex in leukemogenesis and epigenetic regulation. |
| Q33943731 | Mixed lineage leukemia: a structure-function perspective of the MLL1 protein |
| Q27661492 | Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain |
| Q38161393 | Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis |
| Q37620396 | Molecular pathology of mixed-lineage leukemia. |
| Q49550075 | Moonlighting with WDR5: A Cellular Multitasker. |
| Q47849142 | Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia. |
| Q89148846 | Non-coding RNAs in pancreatic cancer: challenges and opportunities for clinical application |
| Q27027360 | On WD40 proteins: propelling our knowledge of transcriptional control? |
| Q24339403 | On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex |
| Q37745350 | PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407. |
| Q34185471 | Perspectives on the discovery of small-molecule modulators for epigenetic processes |
| Q27853186 | Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia |
| Q40522106 | Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes |
| Q28910442 | RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex |
| Q24296408 | Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8 |
| Q35595716 | Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis |
| Q37615671 | SET for life: biochemical activities and biological functions of SET domain-containing proteins |
| Q41848329 | Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 |
| Q27679498 | Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases |
| Q24296678 | Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex |
| Q34399209 | Structural basis for H3K4 trimethylation by yeast Set1/COMPASS. |
| Q24324784 | Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks |
| Q91826930 | Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex |
| Q27667443 | Structure and function of WD40 domain proteins |
| Q27678130 | Structure of the mitotic checkpoint complex |
| Q34208487 | Substrate and product specificities of SET domain methyltransferases |
| Q27676661 | Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance |
| Q50438849 | TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis. |
| Q27727739 | Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes |
| Q37662183 | Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia |
| Q90468310 | Targeting non-bromodomain chromatin readers |
| Q35687836 | Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies? |
| Q50025951 | The COMPASS-like complex promotes flowering and panicle branching in rice. |
| Q92538045 | The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions |
| Q28085683 | The MYC-WDR5 Nexus and Cancer |
| Q38061869 | The many facets of MLL1 regulation |
| Q36736313 | The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation |
| Q27676833 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases |
| Q27692038 | The super elongation complex (SEC) and MLL in development and disease |
| Q37587242 | Towards the construction of an interactome for Human WD40 protein family |
| Q35070909 | Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx. |
| Q36283485 | Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex |
| Q35580822 | WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission |
| Q50043293 | WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress. |
| Q37437287 | WDR5 high expression and its effect on tumorigenesis in leukemia |
| Q58590909 | WDR5 regulates left-right patterning via chromatin dependent and independent functions |
| Q45939385 | WDR5, a complexed protein. |
| Q34278347 | WRAD: enabler of the SET1-family of H3K4 methyltransferases |
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