| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NSMB1119 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/nsmb1119 |
| P932 | PMC publication ID | 4698793 |
| P698 | PubMed publication ID | 16829959 |
| P5875 | ResearchGate publication ID | 6955428 |
| P50 | author | Charles David Allis | Q1064064 |
| Alexander J Ruthenburg | Q57740603 | ||
| Haitao Li | Q30502674 | ||
| P2093 | author name string | Gregory L Verdine | |
| Dinshaw J Patel | |||
| Daina M Graybosch | |||
| Wooikoon Wang | |||
| P2860 | cites work | WD dipeptide motifs and LXXLL motif of chicken HIRA are essential for interactions with the p48 subunit of chromatin assembly factor-1 and histone deacetylase-2 in vitro and in vivo | Q48165535 |
| Catalytic mechanism and product specificity of the histone lysine methyltransferase SET7/9: an ab initio QM/MM-FE study with multiple initial structures. | Q52568420 | ||
| Structure of crystalline alpha-chymotrypsin. IV. The structure of indoleacryloyl-alpha-chyotrypsin and its relevance to the hydrolytic mechanism of the enzyme | Q71626810 | ||
| Translating the Histone Code | Q22065840 | ||
| Regulation of chromatin structure by site-specific histone H3 methyltransferases | Q24290115 | ||
| Structure and catalytic mechanism of the human histone methyltransferase SET7/9 | Q24293093 | ||
| Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus | Q24313196 | ||
| Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 | Q24314963 | ||
| Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase | Q24320001 | ||
| A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3 | Q24531253 | ||
| The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 | Q24536072 | ||
| Electrostatics of nanosystems: application to microtubules and the ribosome | Q24555224 | ||
| Structural basis for the product specificity of histone lysine methyltransferases | Q24646957 | ||
| Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast | Q24678778 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| PROCHECK: a program to check the stereochemical quality of protein structures | Q26778411 | ||
| Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail | Q27638012 | ||
| Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins | Q27860456 | ||
| Use of TLS parameters to model anisotropic displacements in macromolecular refinement | Q27860499 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| PRODRG: a tool for high-throughput crystallography of protein-ligand complexes | Q27860633 | ||
| The Amber biomolecular simulation programs | Q27860745 | ||
| Pushing the boundaries of molecular replacement with maximum likelihood | Q27860922 | ||
| The language of covalent histone modifications | Q27860931 | ||
| Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
| The CCP4 suite: programs for protein crystallography | Q27861090 | ||
| COMPASS: a complex of proteins associated with a trithorax-related SET domain protein | Q27931344 | ||
| Role of histone H3 lysine 27 methylation in Polycomb-group silencing | Q28131795 | ||
| Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF | Q28242466 | ||
| SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex | Q28269256 | ||
| Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae | Q28343956 | ||
| Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. | Q28589560 | ||
| Groucho/TLE family proteins and transcriptional repression | Q28609075 | ||
| MLL targets SET domain methyltransferase activity to Hox gene promoters | Q28609771 | ||
| Active genes are tri-methylated at K4 of histone H3 | Q29547668 | ||
| Genomic maps and comparative analysis of histone modifications in human and mouse | Q29614418 | ||
| Regulation of MLL1 H3K4 methyltransferase activity by its core components | Q29614518 | ||
| Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A | Q29614520 | ||
| Double chromodomains cooperate to recognize the methylated histone H3 tail | Q29614522 | ||
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development | Q29614526 | ||
| Methylation of histone H3 Lys 4 in coding regions of active genes | Q29614680 | ||
| ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation | Q29618299 | ||
| Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability | Q29620365 | ||
| Altered Hox expression and segmental identity in Mll-mutant mice | Q29620391 | ||
| MOLREP: an Automated Program for Molecular Replacement | Q29642797 | ||
| Strength of the Calpha H..O hydrogen bond of amino acid residues | Q31848242 | ||
| MLL associates specifically with a subset of transcriptionally active target genes | Q34078397 | ||
| MLL: a histone methyltransferase disrupted in leukemia | Q34551607 | ||
| Unsafe SETs: histone lysine methyltransferases and cancer | Q34768876 | ||
| Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks | Q36238549 | ||
| Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis. | Q40308284 | ||
| Breaking good resolutions with ARP/wARP. | Q40545795 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 704-712 | |
| P577 | publication date | 2006-07-09 | |
| P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
| P1476 | title | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | |
| P478 | volume | 13 |
| Q90620655 | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5 |
| Q38756663 | A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks |
| Q28480471 | A role for CARM1-mediated histone H3 arginine methylation in protecting histone acetylation by releasing corepressors from chromatin |
| Q27342739 | A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line |
| Q28659947 | A role for WDR5 in TRA-1/Gli mediated transcriptional control of the sperm/oocyte switch in C. elegans |
| Q38307367 | A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer |
| Q38437018 | Acidic domains differentially read histone H3 lysine 4 methylation status and are widely present in chromatin-associated proteins |
| Q39212826 | Alteration of histone H3 lysine 4 trimethylation on putative lytic gene promoters by human Set1 complex during reactivation of Kaposi's sarcoma-associated herpesvirus |
| Q38772574 | An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5. |
| Q42216959 | Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction |
| Q46718839 | Ankyrin for methylated lysines |
| Q52984962 | Arabidopsis JINGUBANG is a Negative Regulator of Pollen Germination that Prevents Pollination in Moist Environments. |
| Q40036063 | Arginine methylation of the histone H3 tail impedes effector binding |
| Q35719929 | Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells |
| Q27665361 | Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2) |
| Q58699689 | Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA |
| Q33577589 | Biophysical characterization of recombinant proteins: a key to higher structural genomics success |
| Q27681419 | CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing |
| Q24306802 | CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation |
| Q33590983 | CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin |
| Q27664073 | Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1 |
| Q35710023 | Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression |
| Q37914154 | Chemical approaches to understand the language of histone modifications |
| Q37528339 | Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers |
| Q34055162 | Chromatin-mediated epigenetic regulation in the malaria parasite Plasmodium falciparum |
| Q33707409 | DCAF26, an adaptor protein of Cul4-based E3, is essential for DNA methylation in Neurospora crassa |
| Q41811756 | Diverse functions of WD40 repeat proteins in histone recognition |
| Q37829706 | Dynamic interplay between histone H3 modifications and protein interpreters: emerging evidence for a "histone language". |
| Q34857637 | Dynamic protein methylation in chromatin biology |
| Q33764436 | Epigenetic regulation of epithelial-mesenchymal transition |
| Q38946185 | Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development |
| Q51134012 | Establishment of the winter-annual growth habit via FRIGIDA-mediated histone methylation at FLOWERING LOCUS C in Arabidopsis. |
| Q41220497 | Exploring the binding diversity of intrinsically disordered proteins involved in one-to-many binding |
| Q48094154 | FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system |
| Q57266571 | Facile target validation in an animal model with intracellularly expressed monobodies |
| Q35850361 | Functional dissection of the ash2 and ash1 transcriptomes provides insights into the transcriptional basis of wing phenotypes and reveals conserved protein interactions |
| Q57948008 | Genome-Wide Profiling of Molecular Recognition of Histone PTMs |
| Q37519403 | Genome-wide Analysis of WD40 Protein Family in Human. |
| Q91643884 | Good News for Nuclear Transgene Expression in Chlamydomonas |
| Q35127065 | HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment |
| Q41074962 | Heat shock factor 1 counteracts epigenetic silencing of nuclear transgenes in Chlamydomonas reinhardtii. |
| Q27006839 | Hijacked in cancer: the KMT2 (MLL) family of methyltransferases |
| Q35351891 | Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase |
| Q37469434 | Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes |
| Q58830255 | Histone Recognition by WD40 Proteins |
| Q29620006 | Histone acetyltransferase complexes: one size doesn't fit all |
| Q36438203 | Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo |
| Q34861446 | Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression |
| Q29547350 | How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers |
| Q24316389 | Identification and characterization of a novel human PP1 phosphatase complex |
| Q37671487 | Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function |
| Q89830480 | Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes |
| Q34255738 | Inner workings and regulatory inputs that control Polycomb repressive complex 2 |
| Q24305393 | Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex |
| Q35922539 | Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 and maintains heterochromatin silencing |
| Q49740926 | LncRNAs regulate cancer metastasis via binding to functional proteins. |
| Q38818070 | Long Non-coding RNAs and their Role in Metastasis |
| Q99415024 | MasterPATH: network analysis of functional genomics screening data |
| Q24295056 | Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive |
| Q38180674 | Mind the methyl: methyllysine binding proteins in epigenetic regulation |
| Q33943731 | Mixed lineage leukemia: a structure-function perspective of the MLL1 protein |
| Q37710711 | Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing. |
| Q38161393 | Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis |
| Q37620396 | Molecular pathology of mixed-lineage leukemia. |
| Q49550075 | Moonlighting with WDR5: A Cellular Multitasker. |
| Q38067764 | One, two, three: how histone methylation is read |
| Q24315922 | PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression |
| Q37446336 | PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation. |
| Q90841057 | PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes |
| Q24303480 | PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation |
| Q37280157 | Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis |
| Q33309162 | Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. |
| Q36821309 | Perceiving the epigenetic landscape through histone readers. |
| Q34185471 | Perspectives on the discovery of small-molecule modulators for epigenetic processes |
| Q27853186 | Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia |
| Q81557015 | Primers on chromatin |
| Q41633957 | Prokaryotic and Highly-Repetitive WD40 Proteins: A Systematic Study |
| Q28910442 | RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex |
| Q38103962 | Readout of epigenetic modifications |
| Q29614518 | Regulation of MLL1 H3K4 methyltransferase activity by its core components |
| Q93032482 | Regulatory mechanisms of B cell responses and the implication in B cell-related diseases |
| Q33701126 | Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2. |
| Q89511226 | Small Molecules Targeting the Specific Domains of Histone-Mark Readers in Cancer Therapy |
| Q41848329 | Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 |
| Q24324008 | Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4 |
| Q27679498 | Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases |
| Q27650923 | Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46 |
| Q24296678 | Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex |
| Q24301311 | Structural basis for molecular recognition and presentation of histone H3 by WDR5 |
| Q24324784 | Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks |
| Q27650473 | Structural basis of histone H4 recognition by p55 |
| Q27667443 | Structure and function of WD40 domain proteins |
| Q27676657 | Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity |
| Q27676661 | Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance |
| Q38455086 | Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction |
| Q38065114 | Systematic analysis of histone modification readout |
| Q27727739 | Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes |
| Q38979643 | Targeting human SET1/MLL family of proteins |
| Q90468310 | Targeting non-bromodomain chromatin readers |
| Q35915446 | The Arginine Methyltransferase PRMT6 Cooperates with Polycomb Proteins in Regulating HOXA Gene Expression |
| Q35676279 | The N terminus of Drosophila ESC binds directly to histone H3 and is required for E(Z)-dependent trimethylation of H3 lysine 27. |
| Q35822529 | The TrxG Complex Mediates Cytokine Induced De Novo Enhancer Formation in Islets |
| Q58740981 | The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation |
| Q50656201 | The epigenetic regulator Cfp1. |
| Q39000118 | The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification |
| Q38061869 | The many facets of MLL1 regulation |
| Q90139907 | The metabolic sensor PASK is a histone 3 kinase that also regulates H3K4 methylation by associating with H3K4 MLL2 methyltransferase complex |
| Q37522825 | The molecular biology of mixed lineage leukemia |
| Q27676833 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases |
| Q35640798 | The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin |
| Q27692038 | The super elongation complex (SEC) and MLL in development and disease |
| Q50517923 | Transcription factor-dependent chromatin remodeling at heat shock and copper-responsive promoters in Chlamydomonas reinhardtii. |
| Q46319993 | Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation |
| Q46323158 | Upon Infection the Cellular WD Repeat-containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication |
| Q35580822 | WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission |
| Q24321162 | WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket |
| Q58590909 | WDR5 regulates left-right patterning via chromatin dependent and independent functions |
| Q55427338 | WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. |
| Q45939385 | WDR5, a complexed protein. |
| Q35253276 | WDSPdb: a database for WD40-repeat proteins |
| Q24300306 | Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes |
| Q36341573 | dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes. |
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