Long Non-coding RNAs and their Role in Metastasis

scientific article published on May 2017

Long Non-coding RNAs and their Role in Metastasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.21873/CGP.20027
P932PMC publication ID5420816
P698PubMed publication ID28446530

P2093author name stringFabian Birzele
Ulrich H Weidle
Gwen Kollmorgen
Rüdiger Rüger
P2860cites workHIF, hypoxia and the role of angiogenesis in non-small cell lung cancerQ36822204
Targeting RNA with small moleculesQ80940656
A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinomaQ87757619
Long noncoding RNA as modular scaffold of histone modification complexesQ22065890
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programsQ24296905
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor PhosphorylationQ24297656
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasisQ24310644
A novel DNA recognition mode by the NF-kappa B p65 homodimerQ24322101
A cytoplasmic NF-κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasisQ24322334
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genesQ24323701
Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expressionQ24338289
Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitorQ24563581
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expressionQ24608592
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasisQ24626854
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adultQ24628036
A coding-independent function of gene and pseudogene mRNAs regulates tumour biologyQ24632651
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4aQ24633736
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transitionQ24649050
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expressionQ24654249
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctionsQ24814569
The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theoryQ26780223
Functions of lncRNA HOTAIR in lung cancerQ26849432
HOTAIR: an oncogenic long non-coding RNA in different cancersQ27002982
The emergence of lncRNAs in cancer biologyQ27024237
Genome regulation by long noncoding RNAs.Q27691812
Wnt/beta-catenin signaling in development and diseaseQ27860784
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1Q27861068
Multiple knockout mouse models reveal lincRNAs are required for life and brain developmentQ28044579
Metastatic colonization by circulating tumour cellsQ28076164
Basic biology and therapeutic implications of lncRNAQ28080732
Possible physiological role of H19 RNAQ28204018
Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-IIQ28218480
TGFbeta in CancerQ28288866
ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarizationQ28593691
The Polycomb complex PRC2 and its mark in lifeQ29547358
Landscape of transcription in human cellsQ29547467
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisitedQ29547915
Long noncoding RNAs with enhancer-like function in human cellsQ29614328
Molecular mechanisms of translational controlQ29614568
The functions and regulation of the PTEN tumour suppressorQ29615536
Tumor metastasis: molecular insights and evolving paradigmsQ29615908
Modular regulatory principles of large non-coding RNAsQ29617829
Molecular mechanisms of long noncoding RNAsQ29618027
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancerQ29620125
The biology of chromatin remodeling complexesQ29620581
Cdc42 promotes transendothelial migration of cancer cells through β1 integrinQ30528220
SELEX experiments: new prospects, applications and data analysis in inferring regulatory pathwaysQ31109037
Functional screen for genes responsible for tamoxifen resistance in human breast cancer cellsQ33246898
Proteome analysis of human androgen-independent prostate cancer cell lines: variable metastatic potentials correlated with vimentin expressionQ33287550
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motifQ33566472
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locusQ33571385
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancerQ33613022
Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancerQ33688617
Requirement for Arf6 in breast cancer invasive activitiesQ33696335
Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transitionQ33868704
Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expressionQ34035303
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation.Q34088908
Citron kinase controls abscission through RhoA and anillinQ34208692
Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancerQ34255976
Molecular basis of metastasis.Q34304177
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cellsQ34317898
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cellsQ34329463
Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence.Q34339927
Intermediate filaments mediate cytoskeletal crosstalkQ34348161
Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosomeQ34438467
Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinomaQ34469248
The metastatic niche: adapting the foreign soilQ36928869
Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancerQ37080366
The RNA coregulator SRA, its binding proteins and nuclear receptor signaling activity.Q37124692
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancerQ37138668
LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancerQ37228983
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational stepQ37241748
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complexQ37266000
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progressionQ37286365
CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlationsQ37381612
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancerQ37390854
Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO.Q37520492
lincRNAs: genomics, evolution, and mechanismsQ37584905
Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-β/Smad signaling pathwayQ37628948
Origins of metastatic traitsQ37720688
TGFbeta signalling: a complex web in cancer progressionQ37760038
Non-coding RNAs: Meet thy mastersQ37764781
Large non-coding RNAs: missing links in cancer?Q37781625
The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.Q37830915
Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expressionQ37914513
Crosstalk between TGF-β signaling and the microRNA machineryQ38011926
Long non-coding RNAs in cancer progressionQ38056501
Long non-coding RNAs: challenges for diagnosis and therapiesQ38079887
The regulatory roles of phosphatases in cancerQ38090432
MALAT1 -- a paradigm for long noncoding RNA function in cancerQ38093120
Targeting long non-coding RNA to therapeutically upregulate gene expressionQ38110692
Control of metastatic progression by microRNA regulatory networksQ38111225
Delivery materials for siRNA therapeuticsQ38154803
Regulation of microRNAs in cancer metastasis.Q38191102
A rationale to target the SWI/SNF complex for cancer therapyQ38220523
De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule TherapeuticsQ38269075
Chromatin regulation: how complex does it get?Q38284263
The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signalingQ38427302
Binding interactions between long noncoding RNA HOTAIR and PRC2 proteinsQ38483070
An overview of the clinical application of antisense oligonucleotides for RNA-targeting therapiesQ38567443
Surviving at a distance: organ specific metastasisQ38676055
Upregulation of long non coding RNA PCAT-1 contributes to cell proliferation, migration and apoptosis in hepatocellular carcinomaQ38781660
Targeting metastasisQ38786658
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.Q38849879
A FOXM1 related long non-coding RNA contributes to gastric cancer cell migrationQ38883049
Long non-coding RNA ANRIL predicts poor prognosis and promotes invasion/metastasis in serous ovarian cancerQ38890636
Long noncoding RNA SPRY4-IT1 predicts poor patient prognosis and promotes tumorigenesis in gastric cancerQ38891609
Non-coding RNAs as drug targetsQ38904908
The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiationQ38927720
lncRNA directs cooperative epigenetic regulation downstream of chemokine signalsQ38938483
Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancerQ38951043
Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancerQ38951842
C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasionQ38960160
CCL21/CCR7 axis activating chemotaxis accompanied with epithelial-mesenchymal transition in human breast carcinomaQ38964160
Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeuticallyQ39109989
Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis.Q39197339
Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transitionQ39327058
Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cellsQ39555908
Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cellsQ39565531
A MicroRNA targeting dicer for metastasis controlQ39684280
Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.Q39986966
Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in non-small cell lung cancer cellsQ40104790
Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesionQ40116507
The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic miceQ40629256
Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate CancerQ41004851
Heterogeneous nuclear ribonucleoprotein K is a DNA-binding transactivatorQ41361383
The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis.Q42122873
Genome-wide nucleosome specificity and directionality of chromatin remodelers.Q42238376
DNA based therapy with diphtheria toxin-A BC-819: a phase 2b marker lesion trial in patients with intermediate risk nonmuscle invasive bladder cancerQ43527075
Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humansQ45334856
Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentinQ45353493
Long intergenic noncoding RNA HOTAIR is overexpressed and regulates PTEN methylation in laryngeal squamous cell carcinoma.Q45938250
Discovery and annotation of long noncoding RNAsQ47573961
Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression.Q50893401
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.Q51856604
Correlation between loss of PTEN expression and Akt phosphorylation in endometrial carcinoma.Q52065384
LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern.Q52871265
HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice.Q53370903
Superoxide dismutases in gastric and esophageal cancer and the prognostic impact in gastric cancer.Q54039560
Evaluation of immunoreactivity for erbB-2 protein as a marker of poor short term prognosis in gastric cancerQ68290745
Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivatorQ77895379
Targeting the Hedgehog pathway in cancerQ79397666
Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 spongeQ34472264
Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expressionQ34544488
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complexQ34546055
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMycQ34558930
Long intergenic noncoding RNAs: new links in cancer progressionQ34676547
Identification of an mRNP complex regulating tumorigenesis at the translational elongation stepQ34701472
Fragile X syndrome, the Fragile X related proteins, and animal modelsQ34733371
The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organsQ34784896
PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.Q35034326
lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6.Q35108871
NF-κB addiction and its role in cancer: 'one size does not fit all'.Q35120893
High expression of long non-coding RNA ANRIL is associated with poor prognosis in hepatocellular carcinoma.Q35632292
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targetsQ35747814
TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT.Q35830257
Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.Q35844784
Decreased long noncoding RNA SPRY4-IT1 contributing to gastric cancer cell metastasis partly via affecting epithelial-mesenchymal transitionQ35910669
Clinical prognostic value of metastasis-associated lung adenocarcinoma transcript 1 in various human cancers: an updated meta-analysisQ35915102
Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progressionQ35930137
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitinationQ36015904
BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migrationQ36021702
RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1.Q36025180
Long noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathwayQ36111552
Malat1 is not an essential component of nuclear speckles in miceQ36114058
Increased expression of the long non-coding RNA ANRIL promotes lung cancer cell metastasis and correlates with poor prognosisQ36142557
Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transitionQ36144048
LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasisQ36179588
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer.Q36356007
The hallmarks of cancer: a long non-coding RNA point of view.Q36391951
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotidesQ36532644
NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2.Q36544861
Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.Q36564164
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.Q36649171
Long non-coding RNA in cancerQ36790436
P433issue3
P304page(s)143-160
P577publication date2017-05-01
P1433published inCancer Genomics and ProteomicsQ15762348
P1476titleLong Non-coding RNAs and their Role in Metastasis
P478volume14

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