Identification and characterization of a novel human PP1 phosphatase complex

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Identification and characterization of a novel human PP1 phosphatase complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.109801
P3181OpenCitations bibliographic resource ID1832733
P932PMC publication ID2915683
P698PubMed publication ID20516061

P2093author name stringDavid G Skalnik
Jeong-Heon Lee
Jinsam You
Erika Dobrota
P2860cites workTOX defines a conserved subfamily of HMG-box proteinsQ21093380
Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cellsQ24291988
Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complexQ24299989
Molecular recognition of histone H3 by the WD40 protein WDR5.Q34546063
Functional diversity of protein phosphatase-1, a cellular economizer and reset buttonQ34649261
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitinationQ34673352
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinasesQ35573568
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinaseQ36033312
Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressedQ36149275
Transcriptional control by chromosome-associated protein phosphatase-1.Q36295505
Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylationQ36824900
Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulationQ37184767
From promiscuity to precision: protein phosphatases get a makeoverQ37414833
Mitotic phosphatases: from entry guards to exit guidesQ37592801
Protein phosphatases take the mitotic stage.Q37600481
Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycleQ39697073
Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosisQ39999461
Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.Q40167547
Protein serine/threonine phosphatases--new avenues for cell regulationQ40611465
PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activityQ40702145
SERCA activity is required for timely progression through G1/S.Q40815360
PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylationQ41875202
Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1.Q42058732
Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylationQ46319993
The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.Q47068298
Serine/threonine protein phosphatase type 1gamma1 is required for the completion of cytokinesis in human A549 lung carcinoma cellsQ73357637
Affinity purification reveals the association of WD40 protein constitutive photomorphogenic 1 with the hetero-oligomeric TCP-1 chaperonin complex in mammalian cellsQ82645712
Dephosphorylation of Rb (Thr-821) in response to cell stressQ83960761
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genesQ24300306
A Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5Q24300798
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complexQ24305512
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligaseQ24306203
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunitQ24308283
Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASSQ24320097
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growthQ24337427
PNUTS enhances in vitro chromosome decondensation in a PP1-dependent mannerQ24531854
Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cellsQ24680202
Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70Q27622544
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligaseQ27640370
Structural basis for regulation of protein phosphatase 1 by inhibitor-2Q27646775
Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylationQ27930951
Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-endsQ27933144
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS.Q27939071
The WD repeat: a common architecture for diverse functionsQ28143827
Protein phosphatase 1--targeted in many directionsQ28200684
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseasesQ28216786
Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-IIQ28218480
CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signalsQ28509015
Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exitQ28755173
The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3Q28776149
Repo-Man recruits PP1 gamma to chromatin and is essential for cell viabilityQ30480368
A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombeQ31025627
Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activityQ32134266
Regulation of protein phosphatase-1.Q33831359
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylationQ34175837
Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.Q34387488
CAT 53: a protein phosphatase 1 nuclear targeting subunit encoded in the MHC Class I region strongly expressed in regions of the brain involved in memory, learning, and Alzheimer's diseaseQ34418956
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complexQ34463476
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complexQ34546055
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
PTW/PP1 phosphatase complexQ21109477
Protein phosphatase 1 catalytic subunit gammaQ21109478
Protein phosphatase 1 catalytic subunit betaQ21109484
Protein phosphatase 1 catalytic subunit alphaQ21116503
WD repeat domain 82Q21124725
TOX high mobility group box family member 4Q21132755
Protein phosphatase 1, regulatory subunit 10Q21989931
P304page(s)24466-76
P577publication date2010-08-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification and characterization of a novel human PP1 phosphatase complex
P478volume285

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