| scholarly article | Q13442814 |
| P2093 | author name string | Jin-Sam You | |
| David G Skalnik | |||
| Jeong-Heon Lee | |||
| Courtney M Tate | |||
| P2860 | cites work | Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. | Q22253233 |
| Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias | Q24294368 | ||
| Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression | Q24297027 | ||
| Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1 | Q24299067 | ||
| Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product | Q24310468 | ||
| Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus | Q24313196 | ||
| Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 | Q24314963 | ||
| Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins | Q24336785 | ||
| Global and Hox-specific roles for the MLL1 methyltransferase | Q24529562 | ||
| A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3 | Q24531253 | ||
| The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 | Q24536072 | ||
| Multiple sequence alignment with the Clustal series of programs | Q24672842 | ||
| The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation | Q27930884 | ||
| COMPASS: a complex of proteins associated with a trithorax-related SET domain protein | Q27931344 | ||
| COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression | Q27938795 | ||
| The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene | Q28201279 | ||
| SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells | Q28270360 | ||
| Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae | Q28343956 | ||
| CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals | Q28509015 | ||
| Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development | Q28587425 | ||
| Histone acetyltransferases | Q29547823 | ||
| Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity | Q29555842 | ||
| Regulation of MLL1 H3K4 methyltransferase activity by its core components | Q29614518 | ||
| The diverse functions of histone lysine methylation | Q29614523 | ||
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development | Q29614526 | ||
| Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression | Q29619380 | ||
| Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena | Q30304568 | ||
| Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia | Q33652400 | ||
| Histone deacetylase activity is required for embryonic stem cell differentiation | Q34294057 | ||
| CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex | Q34463476 | ||
| Histones and histone modifications | Q35842800 | ||
| 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene | Q35865236 | ||
| Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases | Q36408191 | ||
| Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos. | Q43728480 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | RB binding protein 5, histone lysine methyltransferase complex subunit | Q21102079 |
| histone methyltransferase activity (H3-K4 specific) | Q21102097 | ||
| CXXC finger protein 1 | Q21112084 | ||
| SET domain containing 1A, histone lysine methyltransferase | Q21115985 | ||
| WD repeat domain 82 | Q21124725 | ||
| SET domain containing 1B, histone lysine methyltransferase | Q21125184 | ||
| ASH2 like, histone lysine methyltransferase complex subunit | Q21130031 | ||
| WD repeat domain 5 | Q21171851 | ||
| P304 | page(s) | 13419-28 | |
| P577 | publication date | 2007-05-04 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex | |
| P478 | volume | 282 |
| Q33581427 | A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression |
| Q47402248 | A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism |
| Q34875163 | A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation |
| Q92172253 | A novel de novo frameshift variant in SETD1B causes epilepsy |
| Q34536856 | A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex |
| Q39541423 | ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes |
| Q34235555 | Affinity purification of MLL3/MLL4 histone H3K4 methyltransferase complex |
| Q98613077 | Age-dependent expression of cancer-related genes in a long-lived seabird |
| Q39212826 | Alteration of histone H3 lysine 4 trimethylation on putative lytic gene promoters by human Set1 complex during reactivation of Kaposi's sarcoma-associated herpesvirus |
| Q33523037 | Alternative epigenetic chromatin states of polycomb target genes |
| Q33761102 | An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain |
| Q48799738 | An atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectual disability. |
| Q46925893 | Antagonistic functions of SET-2/SET1 and HPL/HP1 proteins in C. elegans development |
| Q36590643 | Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr. |
| Q35660192 | Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters |
| Q35172965 | Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation |
| Q47295917 | Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer |
| Q37369316 | CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes |
| Q99594988 | COMPASS and SWI/SNF complexes in development and disease |
| Q37247874 | CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation |
| Q33590983 | CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin |
| Q39303678 | Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells |
| Q35710023 | Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression |
| Q38578748 | Comprehensive Catalog of Currently Documented Histone Modifications |
| Q39921786 | Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression |
| Q97424722 | Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family |
| Q57183364 | CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands |
| Q37061200 | CpG islands influence chromatin structure via the CpG-binding protein Cfp1. |
| Q37476097 | DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells |
| Q47256933 | DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism |
| Q89136390 | DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications |
| Q50098318 | De novo variants in SETD1B are associated with intellectual disability, epilepsy and autism. |
| Q92803739 | De novo variants in SETD1B cause intellectual disability, autism spectrum disorder, and epilepsy with myoclonic absences |
| Q38239864 | Deciphering the epigenetic code of T lymphocytes |
| Q35833904 | Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1. |
| Q41449642 | Development and Use of Assay Conditions Suited to Screening for and Profiling of SET-Domain-Targeted Inhibitors of the MLL/SET1 Family of Lysine Methyltransferases |
| Q35077007 | Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin |
| Q37030360 | Dose-responsive gene expression in suberoylanilide hydroxamic acid-treated resting CD4+ T cells. |
| Q35177234 | Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription. |
| Q28594517 | Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation |
| Q37455875 | Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity. |
| Q36464986 | Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4 |
| Q38845518 | Epigenetic Changes in Diabetes and Cardiovascular Risk. |
| Q37742439 | Epigenetic regulation of development by histone lysine methylation. |
| Q36180821 | Epigenetic transcriptional memory |
| Q33521703 | Fgfr3 is a transcriptional target of Ap2delta and Ash2l-containing histone methyltransferase complexes |
| Q92538775 | Gene fusion analysis in renal cell carcinoma by FusionPlex RNA-sequencing and correlations of molecular findings with clinicopathological features |
| Q35767753 | Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality |
| Q64103396 | Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas |
| Q37961731 | Grasping trimethylation of histone H3 at lysine 4. |
| Q58600615 | H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development |
| Q34547967 | H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability. |
| Q40088947 | H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass |
| Q36692863 | H3K4 methyltransferase Set1 is involved in maintenance of ergosterol homeostasis and resistance to Brefeldin A. |
| Q55617657 | H3K4me3 and Wdr82 are associated with tumor progression and a favorable prognosis in human colorectal cancer. |
| Q64229246 | High‑level SETD1B gene expression is associated with unfavorable prognosis in hepatocellular carcinoma |
| Q27006839 | Hijacked in cancer: the KMT2 (MLL) family of methyltransferases |
| Q37585674 | Histone H3 lysine 4 (H3K4) methylation in development and differentiation |
| Q38156524 | Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells |
| Q55658855 | Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. |
| Q24316389 | Identification and characterization of a novel human PP1 phosphatase complex |
| Q37134376 | Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation. |
| Q37066017 | Incorporating parental information into family-based association tests |
| Q38163405 | Integrating DNA methylation dynamics into a framework for understanding epigenetic codes |
| Q37457961 | Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells |
| Q33652604 | Introduction--Epiphanies in epigenetics. |
| Q35211551 | Lineage-specific regulation of epigenetic modifier genes in human liver and brain |
| Q51539776 | MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB. |
| Q37573260 | Mammalian cytosine methylation at a glance. |
| Q37794100 | Mediators and dynamics of DNA methylation |
| Q33943731 | Mixed lineage leukemia: a structure-function perspective of the MLL1 protein |
| Q52369540 | Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin. |
| Q38161393 | Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis |
| Q37845655 | Molecular coupling of DNA methylation and histone methylation |
| Q37802429 | Molecular mechanisms by which T-bet regulates T-helper cell commitment |
| Q24320097 | Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS |
| Q49550075 | Moonlighting with WDR5: A Cellular Multitasker. |
| Q90639985 | N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis |
| Q41924562 | Nuclear speckles: molecular organization, biological function and role in disease |
| Q24339403 | On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex |
| Q38662822 | One-carbon metabolism and epigenetics: understanding the specificity |
| Q28109656 | Orphan CpG islands identify numerous conserved promoters in the mammalian genome |
| Q34271089 | Photoperiod influences growth and mll (mixed-lineage leukaemia) expression in Atlantic cod. |
| Q90644667 | Physical and functional interaction between SET1/COMPASS complex component CFP-1 and a Sin3S HDAC complex in C. elegans |
| Q92877957 | Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function |
| Q34752160 | Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes |
| Q40522106 | Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes |
| Q39922110 | Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. |
| Q34395567 | Rbm15-Mkl1 interacts with the Setd1b histone H3-Lys4 methyltransferase via a SPOC domain that is required for cytokine-independent proliferation |
| Q36827433 | Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes |
| Q34575655 | Repeat expansion affects both transcription initiation and elongation in friedreich ataxia cells |
| Q39313225 | Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation |
| Q93048662 | SET domain containing 1B gene is mutated in primary hepatic neuroendocrine tumors |
| Q24310032 | SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53 |
| Q27932981 | Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory |
| Q47728298 | Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program. |
| Q27679498 | Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases |
| Q26825534 | Structural and functional coordination of DNA and histone methylation |
| Q42717294 | Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation |
| Q27727739 | Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes |
| Q41616680 | Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia. |
| Q34211667 | The COMPASS family of H3K4 methylases in Drosophila |
| Q38015891 | The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis |
| Q38628109 | The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function |
| Q92538045 | The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions |
| Q34566036 | The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes |
| Q34625800 | The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis |
| Q50656201 | The epigenetic regulator Cfp1. |
| Q37172487 | The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis |
| Q24294424 | The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation |
| Q27676833 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases |
| Q27667275 | The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain |
| Q27692038 | The super elongation complex (SEC) and MLL in development and disease |
| Q64057207 | Theoretical analysis of Polycomb-Trithorax systems predicts that poised chromatin is bistable and not bivalent |
| Q34765363 | USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription |
| Q94563005 | Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation |
| Q36283485 | Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex |
| Q30426429 | WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. |
| Q34278347 | WRAD: enabler of the SET1-family of H3K4 methyltransferases |
| Q24300306 | Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes |
| Q92099533 | Why are so many MLL lysine methyltransferases required for normal mammalian development? |
| Q36936680 | ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection |
| Q35644753 | dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development |
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