The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein

scientific article

The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1432-1033.1995.TB20703.X
P3181OpenCitations bibliographic resource ID4425515
P698PubMed publication ID7635144

P50authorJeremy A. SquireQ39802515
P2093author name stringH Schachter
J Tan
M Sarkar
P Leong
B Bendiak
F Reck
A F D'Agostaro
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formationQ24305921
Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N-acetylglucosaminyltransferase gene familyQ24322660
cDNA cloning and chromosomal mapping of human N-acetylglucosaminyltransferase V+Q24336645
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigenQ24563666
Production of Human Beta Interferon in Insect Cells Infected with a Baculovirus Expression VectorQ24604122
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A simple method for displaying the hydropathic character of a proteinQ26778481
cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III)Q28117665
High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clonesQ28274183
Cloning and expression of the murine gene and chromosomal location of the human gene encoding N-acetylglucosaminyltransferase IQ28511486
Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine: α-3-D-mannoside β-1,2-N-acetylglucosaminyltransferase I geneQ28610146
Mammalian glycosyltransferases: genomic organization and protein structureQ30335290
Murine beta 1,4-galactosyltransferase: round spermatid transcripts are characterized by an extended 5'-untranslated regionQ30990972
Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase IQ33318026
Carbohydrate deficient glycoprotein syndrome type II: a deficiency in Golgi localised N-acetyl-glucosaminyltransferase II.Q33624870
Molecular genetic basis of the histo-blood group ABO system.Q34323307
GlycosylationQ35659693
Glycosylation engineeringQ36215708
Molecular cloning and expression of chick embryo Gal beta 1,4GlcNAc alpha 2,6-sialyltransferase. Comparison with the mammalian enzymeQ36762498
Cell surface beta 1,4 galactosyltransferase: twenty years laterQ37068100
Human α1–3 fucosyltransferasesQ37068109
The 'yellow brick road' to branched complex N-glycansQ37135294
Modification and secretion of human interleukin 2 produced in insect cells by a baculovirus expression vectorQ37539177
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.Q37631574
Subcellular organization of glycosylation in mammalian cellsQ39668642
Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharidesQ39735775
The molecular and cell biology of glycosyltransferasesQ40800762
Synthesis of tetrasaccharide analogues of the N-glycan substrate of beta-(1-->2)-N-acetylglucosaminyltransferase II using trisaccharide precursors and recombinant beta-(1-->2)-N-acetylglucosaminyltransferase I.Q41461985
Processing of asparagine-linked oligosaccharides in insect cells. N-acetylglucosaminyltransferase I and II activities in cultured lepidopteran cellsQ41512282
Deletion analysis of the NH2-terminal region of beta-1,4-galactosyltransferaseQ41625333
Expression of recombinant rabbit UDP-GlcNAc: alpha 3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I catalytic domain in Sf9 insect cellsQ42068430
Cloning of a cDNA encoding N-acetylglucosaminyltransferase I from rat liver and analysis of its expression in rat tissuesQ48086831
Molecular cloning and characterization of the mouse UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I geneQ48179419
Alpha 1----3-galactosyltransferase: the use of recombinant enzyme for the synthesis of alpha-galactosylated glycoconjugates.Q52449083
Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosaQ67297773
Rapid physical mapping of cloned DNA on banded mouse chromosomes by fluorescence in situ hybridizationQ67737800
Determination of N-acetylglucosaminyltransferases III, IV and V in normal and hepatoma tissues of ratsQ68428555
Synthetic substrate analogues for UDP-GlcNAc: Man alpha 1-6R beta(1-2)-N-acetylglucosaminyltransferase II. Substrate specificity and inhibitors for the enzymeQ72499913
Modes of DAPI banding and simultaneous in situ hybridizationQ72815252
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinsectQ1390
protein N-linked glycosylation via asparagineQ14633895
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferaseQ21119445
P304page(s)317-328
P577publication date1995-07-01
P1433published inFEBS JournalQ1388041
P1476titleThe human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein
P478volume231

Reverse relations

cites work (P2860)
Q22010001A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment
Q36084452A systematic framework to derive N-glycan biosynthesis process and the automated construction of glycosylation networks
Q50296334Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
Q40656754Alteration in the expression of early stage processing enzymes of N-glycan during myeloid and monocytoid differentiation of HL-60 cells
Q33778404Carbohydrate-deficient glycoprotein syndrome type II.
Q30987084Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.
Q24292023Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I
Q56566912Cloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I
Q35932897Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines
Q33269616Construction and characterization of new piggyBac vectors for constitutive or inducible expression of heterologous gene pairs and the identification of a previously unrecognized activator sequence in piggyBac.
Q45316541Defective MGAT2 causes CDG-2a
Q50289221Defective MGAT2 does not transfer GlcNAc to N-glycans
Q59488876Development of recombinant, immobilised β-1,4-mannosyltransferase for use as an efficient tool in the chemoenzymatic synthesis of N-linked oligosaccharides
Q30873680Engineering the protein N-glycosylation pathway in insect cells for production of biantennary, complex N-glycans.
Q41102270Expression of stable human O-glycan core 2 beta-1,6-N-acetylglucosaminyltransferase in Sf9 insect cells
Q40985602Expression of three Caenorhabditis elegans N-acetylglucosaminyltransferase I genes during development
Q34989525Golgi alpha-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals
Q40659743Improvement of glycosylation in insect cells with mammalian glycosyltransferases
Q35249929Localization of the congenital dyserythropoietic anemia II locus to chromosome 20q11.2 by genomewide search
Q47241756Medial Golgi but not late Golgi glycosyltransferases exist as high molecular weight complexes. Role of luminal domain in complex formation and localization
Q28589941Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa
Q48378134Molecular cloning of cDNA encoding N-acetylglucosaminyltransferase II from Arabidopsis thaliana
Q36890668Molecular cloning of the porcine beta-1,2-N-acetylglucosaminyltransferase II gene and assignment to chromosome 1q23-q27.
Q24675799Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development
Q39324563N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147.
Q24530034Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis
Q43976499Protein N-glycosylation: molecular genetics and functional significance
Q31958280Quality assessment of whole genome mapping data in the refined familial spastic paraplegia interval on chromosome 14q.
Q41071120Recent progress in the molecular biology of the cloned N-acetylglucosaminyltransferases
Q38313554Regulation of expression of the human beta-1,2-N-acetylglucosaminyltransferase II gene (MGAT2) by Ets transcription factors
Q38362425Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin.
Q74476723Studies on the conformational behaviour of GlcNAc-Man3-GlcNAc2 oligosaccharides using molecular dynamics simulations
Q35801895Substrate specificities and intracellular distributions of three N-glycan processing enzymes functioning at a key branch point in the insect N-glycosylation pathway
Q34504298The congenital disorders of glycosylation: a multifaceted group of syndromes
Q34290881The joys of HexNAc. The synthesis and function of N- and O-glycan branches
Q34989555The role of the GlcNAc(beta)1,2Man(alpha)- moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-D-mannoside bet
Q22008777Tissue specific expression and chromosomal mapping of a human UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N-acetylglucosaminyltransferase
Q38337853Transcriptional regulation of the human UDP-GlcNAc:alpha-6-D-mannoside beta-1-2-N-acetylglucosaminyltransferase II gene (MGAT2) which controls complex N-glycan synthesis
Q33187470Two closely related forms of UDP-GlcNAc: alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II occur in the clawed frog Xenopus laevis
Q34989546UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans
Q38348707Use of Synthetic Oligosaccharide Substrate Analogs to Map the Active Sites of N-Acetylglucosaminyltransferases I and II
Q30430310cDNA cloning and expression of bovine UDP-N-acetylglucosamine: alpha1, 3-D-mannoside beta1,4-N-acetylglucosaminyltransferase IV.

Search more.