Cloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I

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Cloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I is …
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scholarly articleQ13442814

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P356DOI10.1042/0264-6021:3610153
P932PMC publication ID1222290
P698PubMed publication ID11742540
P5875ResearchGate publication ID247447703

P50authorDoron BetelQ28914806
P2093author name stringDoron BETEL
Harry SCHACHTER
Wenli ZHANG
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1Q24291905
Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formationQ24305921
The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant proteinQ24321959
Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesisQ24530034
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A simple method for displaying the hydropathic character of a proteinQ26778481
X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamilyQ27627480
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functionsQ28139075
A role of dystroglycan in schwannoma cell adhesion to lamininQ28238357
Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrixQ28296676
Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydratesQ28588255
Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null miceQ28590908
Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.Q30987084
A new beta-1,2-N-acetylglucosaminyltransferase that may play a role in the biosynthesis of mammalian O-mannosyl glycansQ31958365
Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase IQ33318026
Divergent evolution of fucosyltransferase genes from vertebrates, invertebrates, and bacteriaQ33544296
O-mannosyl glycans in mammalsQ33783762
Glycosylation engineeringQ36215708
alpha-Dystroglycan is a laminin receptor involved in extracellular matrix assembly on myotubes and muscle cell viability.Q36256527
The 'yellow brick road' to branched complex N-glycansQ37135294
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.Q37631574
Detection of O-mannosyl glycans in rabbit skeletal muscle alpha-dystroglycanQ38330780
Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with lamininQ38349218
Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharidesQ39735775
Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase.Q40938890
Expression of three Caenorhabditis elegans N-acetylglucosaminyltransferase I genes during developmentQ40985602
Synthesis of tetrasaccharide analogues of the N-glycan substrate of beta-(1-->2)-N-acetylglucosaminyltransferase II using trisaccharide precursors and recombinant beta-(1-->2)-N-acetylglucosaminyltransferase I.Q41461985
Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptideQ41695196
Control of glycoprotein synthesis: substrate specificity of rat liver UDP-GlcNAc:Man alpha 3R beta 2-N-acetylglucosaminyltransferase I using synthetic substrate analoguesQ41847910
Expression of recombinant rabbit UDP-GlcNAc: alpha 3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I catalytic domain in Sf9 insect cellsQ42068430
Characterization of dp6troglycan-laminin interaction in peripheral nerve.Q42517423
Control of glycoprotein synthesis. Purification and characterization of rabbit liver UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.Q50895693
In the biosynthesis of N-glycans in connective tissue of the snail Lymnaea stagnalis of incorporation GlcNAc by beta 2GlcNAc-transferase I is an essential prerequisite for the action of beta 2GlcNAc-transferase II and beta 2Xyl-transferaseQ71735078
Biosynthesis of dystroglycan: processing of a precursor propeptideQ73466595
Complex N-glycans in Mgat1 null preimplantation embryos arise from maternal Mgat1 RNAQ73861297
Removal of 106 amino acids from the N-terminus of UDP-GlcNAc: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I does not inactivate the enzymeQ74476726
A role for dystroglycan in basement membrane assemblyQ77726339
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)153
P577publication date2002-01-01
P1433published inBiochemical JournalQ864221
P1476titleCloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I
P478volume361

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cites work (P2860)
Q36720784Adeno-associated viral-mediated LARGE gene therapy rescues the muscular dystrophic phenotype in mouse models of dystroglycanopathy
Q30400284Biochemical correlation of activity of the α-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in muscle-eye-brain disease.
Q46480778Characterization of mice with targeted deletion of the gene encoding core 2 beta1,6-N-acetylglucosaminyltransferase-2.
Q33566548Comparison of the substrate specificities and catalytic properties of the sister N-acetylglucosaminyltransferases, GnT-V and GnT-Vb (IX).
Q36790131Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development
Q36855555Congenital muscular dystrophies involving the O-mannose pathway
Q36217346Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V
Q34217566Differential glycosylation of α-dystroglycan and proteins other than α-dystroglycan by like-glycosyltransferase
Q37609175Dissecting the molecular basis of the role of the O-mannosylation pathway in disease: α-dystroglycan and forms of muscular dystrophy
Q37261423Dystroglycan glycosylation and muscular dystrophy.
Q24302249Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues
Q48259029Enzymatic diagnostic test for Muscle-Eye-Brain type congenital muscular dystrophy using commercially available reagents
Q94570299Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors
Q38240078Finding the sweet spot: assembly and glycosylation of the dystrophin-associated glycoprotein complex
Q28587952Glycosylation defects: a new mechanism for muscular dystrophy?
Q28509840Glycosyltransferase function in core 2-type protein O glycosylation
Q39024764Induction of Antibodies Directed Against Branched Core O-Mannosyl Glycopeptides-Selectivity Complimentary to the ConA Lectin
Q44473143Inhibition of dystroglycan cleavage causes muscular dystrophy in transgenic mice
Q50336131Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes
Q47375901LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies.
Q33886100LARGE expression augments the glycosylation of glycoproteins in addition to α-dystroglycan conferring laminin binding
Q26860991Mammalian O-mannosylation: unsolved questions of structure/function
Q34989520Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy
Q46036955Novel POMGnT1 mutations cause muscle-eye-brain disease in Chinese patients.
Q38647928Novel copy number variation of POMGNT1 associated with muscle-eye-brain disease detected by next-generation sequencing
Q24602380Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression
Q37723603Protein O-mannosylation in animal development and physiology: from human disorders to Drosophila phenotypes
Q34980261Protein O-mannosylation: conserved from bacteria to humans
Q36981050Receptor tyrosine phosphatase beta (RPTPbeta) activity and signaling are attenuated by glycosylation and subsequent cell surface galectin-1 binding
Q34032485Retinal ectopias and mechanically weakened basement membrane in a mouse model of muscle-eye-brain (MEB) disease congenital muscular dystrophy
Q35222634Synthetic, structural, and biosynthetic studies of an unusual phospho-glycopeptide derived from α-dystroglycan
Q35824015The role of defective glycosylation in congenital muscular dystrophy
Q34989555The role of the GlcNAc(beta)1,2Man(alpha)- moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-D-mannoside bet

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