Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells

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Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...514439P
P356DOI10.1371/JOURNAL.PONE.0014439
P8608Fatcat IDrelease_rjbk4h4gbzf2vdi5moizwz3llu
P932PMC publication ID3010979
P698PubMed publication ID21203429
P5875ResearchGate publication ID49726224

P50authorMatthias MörgelinQ28805358
Ladan ParhamifarQ59104461
Frederik VilhardtQ40592076
P2093author name stringAnita Sjölander
Wondossen Sime
Yuliana Yudina
P2860cites workCharacterization of the human cysteinyl leukotriene CysLT1 receptorQ22010199
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Regulation of cysteinyl leukotriene type 1 receptor internalization and signalingQ28297665
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activationQ50335944
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Caveolin-1 regulates cellular trafficking and function of the glucagon-like Peptide 1 receptor.Q50717874
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Low temperature embedding with Lowicryl resins: two new formulations and some applicationsQ69928849
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Which patients with asthma could benefit from using anti-leukotriene drugs: an evidence based reviewQ83316185
Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestinsQ95761766
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Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11Q29615018
Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signalingQ30014843
Leukotrienes induce cell-survival signaling in intestinal epithelial cellsQ33181305
G protein-coupled receptor sorting to endosomes and lysosomesQ33848408
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CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cellsQ34662206
The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacologyQ35047674
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Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors.Q36562727
Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesiaQ36675651
Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cellsQ36711106
Clathrin-dependent mechanisms of G protein-coupled receptor endocytosisQ36765864
Regulation of GPCRs by endocytic membrane trafficking and its potential implicationsQ37053838
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Role of eicosanoids as mediators of inflammation in inflammatory bowel diseaseQ37590359
PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activationQ39337678
Inhibition of dynamin prevents CCL2-mediated endocytosis of CCR2 and activation of ERK1/2.Q39818808
Caveolin 2 regulates endocytosis and trafficking of the M1 muscarinic receptor in MDCK epithelial cellsQ40168372
Endogenous production of leukotriene D4 mediates autocrine survival and proliferation via CysLT1 receptor signalling in intestinal epithelial cellsQ40277131
The inflammatory mediator leukotriene D4 induces beta-catenin signaling and its association with antiapoptotic Bcl-2 in intestinal epithelial cellsQ40331160
Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells.Q40405407
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.Q40459685
The pro-inflammatory mediator leukotriene D4 induces phosphatidylinositol 3-kinase and Rac-dependent migration of intestinal epithelial cells.Q40469648
Lipid mediator networks in cell signaling: update and impact of cytokines.Q41073474
Low expression of CysLT1R and high expression of CysLT2R mediate good prognosis in colorectal cancerQ43197500
Regulation of eNOS expression in brain endothelial cells by perinuclear EP(3) receptorsQ43948824
Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cellsQ43961374
Diverse pathways for nuclear signaling by G protein-coupled receptors and their ligandsQ44015713
Leukotriene D4 mediates survival and proliferation via separate but parallel pathways in the human intestinal epithelial cell line Int 407.Q44329577
CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.Q46818525
An increased expression of cysteinyl leukotriene 2 receptor in colorectal adenocarcinomas correlates with high differentiationQ46972184
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)e14439
P577publication date2010-01-01
P1433published inPLOS OneQ564954
P1476titleLigand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells
P478volume5

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cites work (P2860)
Q36952174An eicosanoid-centric view of atherothrombotic risk factors
Q38196401Biophysical Detection of Diversity and Bias in GPCR Function
Q28536784CysLT(1)R antagonists inhibit tumor growth in a xenograft model of colon cancer
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Q33823711Cysteinyl leukotriene receptor 1 mediates LTD4-induced activation of mouse microglial cells in vitro
Q28308101Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer
Q46011006Leukotriene C4 aggravates bleomycin-induced pulmonary fibrosis in mice.
Q34453454Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells

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