| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Ferguson SS | |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | G protein-coupled receptor | Q38173 |
| endocytosis | Q189814 | ||
| desensitization | Q2700499 | ||
| P304 | page(s) | 1-24 | |
| P577 | publication date | 2001-03-01 | |
| P1433 | published in | Pharmacological Reviews | Q2085079 |
| P1476 | title | Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling | |
| P478 | volume | 53 |
| Q35210020 | 'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass? |
| Q39158190 | A "tail" of opioid receptor variants. |
| Q41843794 | A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate |
| Q57038660 | A Critical Role for Sorting Nexin 1 in the Trafficking of Metabotropic Glutamate Receptors |
| Q33811648 | A GPR54-activating mutation in a patient with central precocious puberty. |
| Q28581149 | A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalization |
| Q35112448 | A constitutively active mutant of the human lutropin receptor (hLHR-L457R) escapes lysosomal targeting and degradation |
| Q42428339 | A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity |
| Q28569075 | A dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin binding |
| Q37416102 | A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae |
| Q37260432 | A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. |
| Q28258154 | A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation |
| Q24634320 | A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy |
| Q35978006 | A quantitative characterization of the yeast heterotrimeric G protein cycle |
| Q33580640 | A rapid and efficient immunoenzymatic assay to detect receptor protein interactions: G protein-coupled receptors |
| Q34159374 | A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation |
| Q33783543 | ADP-ribosylation factor 6 modulates adrenergic stimulated lipolysis in adipocytes |
| Q36513501 | AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases |
| Q37430687 | AT1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through a microtubule-dependent endocytic pathway |
| Q36374225 | AT1-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers |
| Q24647504 | ATP stimulates GRK-3 phosphorylation and beta-arrestin-2-dependent internalization of P2X7 receptor |
| Q36948985 | Accuracy of direct gradient sensing by single cells |
| Q36348397 | Achieving global perfect homeostasis through transporter regulation |
| Q27301914 | Acoustofluidic chemical waveform generator and switch. |
| Q36987597 | Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling |
| Q37635019 | Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization |
| Q48000733 | Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction |
| Q36308913 | Adenosine mediated desensitization of cAMP signaling enhances T-cell responses |
| Q37349756 | Adrenergic nervous system in heart failure: pathophysiology and therapy |
| Q35978097 | Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors. |
| Q39979395 | Agonist-dependent internalization and trafficking of the human prostacyclin receptor: a direct role for Rab5a GTPase |
| Q28740731 | Agonist-directed desensitization of the β2-adrenergic receptor |
| Q34348578 | Agonist-induced internalization of kappa-opioid receptors in noradrenergic neurons of the rat locus coeruleus |
| Q51806501 | Agonist-induced internalization of the Caenorhabditis elegans muscarinic acetylcholine receptor GAR-3 in Chinese hamster ovary cells. |
| Q34722029 | Agonist-selective mechanisms of GPCR desensitization |
| Q38464958 | Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies |
| Q30486708 | Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2 |
| Q33234898 | Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor |
| Q35874442 | Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation |
| Q59808947 | Alterations of Expression of the Serotonin 5-HT4 Receptor in Brain Disorders |
| Q33632079 | Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. |
| Q37406229 | Amantadine inhibits platelet-activating factor induced clathrin-mediated endocytosis in human neutrophils |
| Q35673827 | An antinociceptive role for substance P in acid-induced chronic muscle pain |
| Q33761154 | An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis |
| Q41814772 | Angiotensin (1-7) induces MAS receptor internalization. |
| Q64059656 | Angiotensin II Induces Automatic Activity of the Isolated Guinea Pig Pulmonary Vein Myocardium through Activation of the IP₃ Receptor and the Na⁺-Ca Exchanger |
| Q36921929 | Angiotensin II excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: an in vitro patch-clamp study in brain slices |
| Q34410883 | Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans |
| Q39938297 | Arrestin 3 mediates endocytosis of CCR7 following ligation of CCL19 but not CCL21. |
| Q36953762 | Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences |
| Q37351549 | Arrestin3 mediates D(2) dopamine receptor internalization |
| Q24670380 | Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate |
| Q35972396 | Bacillus bombysepticus α-Toxin Binding to G Protein-Coupled Receptor Kinase 2 Regulates cAMP/PKA Signaling Pathway to Induce Host Death |
| Q39267607 | Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks |
| Q41954109 | Beta-adrenergic receptor signaling in cardiac function and heart failure |
| Q34569418 | Beta-arrestin2-mediated internalization of mammalian odorant receptors. |
| Q34752710 | Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains |
| Q33890802 | Beyond desensitization: physiological relevance of arrestin-dependent signaling. |
| Q37551908 | Biased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and Pathology |
| Q47648103 | Biased signaling by thyroid-stimulating hormone receptor-specific antibodies determines thyrocyte survival in autoimmunity. |
| Q39651000 | Bradykinin increases resensitization of purinergic receptor signaling in glioma cells. |
| Q37049094 | Brain angiotensin receptors and binding proteins |
| Q33670087 | Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway |
| Q34186015 | CB2 Cannabinoid receptors as a therapeutic target-what does the future hold? |
| Q37310767 | CK2 negatively regulates Galphas signaling |
| Q39076762 | CK2-An Emerging Target for Neurological and Psychiatric Disorders |
| Q30494303 | CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling |
| Q41811634 | Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid |
| Q44608465 | CaVβ subunit-mediated up-regulation of CaV2.2 currents triggered by D2 dopamine receptor activation |
| Q39806323 | Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling |
| Q35009538 | Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and beta-arrestin-2 recruitment: a mechanism regulating stress and anxiety responses |
| Q30487855 | Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway |
| Q30746055 | Cell-Based High-Throughput Screening Assay System for Monitoring G Protein-Coupled Receptor Activation Using β-Galactosidase Enzyme Complementation Technology |
| Q42098279 | Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex. |
| Q33927508 | Chaperoning G protein-coupled receptors: from cell biology to therapeutics |
| Q44346280 | Characterization of functional μ opioid receptor turnover in rat locus coeruleus: an electrophysiological and immunocytochemical study. |
| Q37244709 | Characterization of intracellular signaling mediated by human somatostatin receptor 5: role of the DRY motif and the third intracellular loop |
| Q37165951 | Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells |
| Q36184275 | Chemokine receptor internalization and intracellular trafficking |
| Q35849720 | Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8+ T-cell responses |
| Q36403878 | Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. |
| Q35080516 | Cholesterol regulates micro-opioid receptor-induced beta-arrestin 2 translocation to membrane lipid rafts |
| Q34348557 | Chronic exposure to the chemokine CCL3 enhances neuronal network activity in rat hippocampal cultures. |
| Q39832239 | Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain |
| Q24530597 | Clathrin-dependent endocytosis |
| Q36191614 | Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. |
| Q37594742 | Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction |
| Q41206403 | Conducting the G-protein Coupled Receptor (GPCR) Signaling Symphony in Cardiovascular Diseases: New Therapeutic Approaches |
| Q30485797 | Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis |
| Q34376293 | Constitutive phosphorylation by protein kinase C regulates D1 dopamine receptor signaling |
| Q39797234 | Contrasting effects of allosteric and orthosteric agonists on m1 muscarinic acetylcholine receptor internalization and down-regulation |
| Q41820552 | Control of signalling efficacy by palmitoylation of the rat Y1 receptor |
| Q64263436 | Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice |
| Q36776746 | Cross-desensitization and cointernalization of H1 and H2 histamine receptors reveal new insights into histamine signal integration. |
| Q33672477 | Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1. |
| Q35978165 | Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor |
| Q37232104 | Current and future G protein-coupled receptor signaling targets for heart failure therapy |
| Q42000724 | Deciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells |
| Q38042614 | Decoding high Gonadotropin-releasing hormone pulsatility: a role for GnRH receptor coupling to the cAMP pathway? |
| Q35645970 | Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma |
| Q39873859 | Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3. |
| Q33374405 | Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit |
| Q33685883 | Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling |
| Q34568429 | Demonstration of Angiotensin II-induced Ras Activation in the trans-Golgi Network and Endoplasmic Reticulum Using Bioluminescence Resonance Energy Transfer-based Biosensors |
| Q41991082 | Desensitization and internalization of endothelin receptor A: impact of G protein-coupled receptor kinase 2 (GRK2)-mediated phosphorylation |
| Q34999097 | Desensitization by progressive up-titration prevents first-dose effects on the heart: guinea pig study with ponesimod, a selective S1P1 receptor modulator |
| Q33824363 | Desensitization of beta-adrenergic receptors in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog |
| Q35044948 | Desensitization of beta2-adrenoceptor-mediated responses by short-acting beta2-adrenoceptor agonists in human lung mast cells. |
| Q34049673 | Desensitization of mu-opioid receptor-evoked potassium currents: initiation at the receptor, expression at the effector |
| Q38173743 | Desensitization properties of P2X3 receptors shaping pain signaling |
| Q34746623 | Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting |
| Q38187199 | Different mechanisms of homologous and heterologous μ-opioid receptor phosphorylation |
| Q36324611 | Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor |
| Q35034819 | Differential binding of calmodulin to group I metabotropic glutamate receptors regulates receptor trafficking and signaling |
| Q43890669 | Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors. |
| Q44477197 | Differential frequency dependence of P2Y1- and P2Y2- mediated Ca 2+ signaling in astrocytes. |
| Q44532496 | Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors. |
| Q47279841 | Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain |
| Q33765419 | Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells. |
| Q34227284 | Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy |
| Q34947403 | Disease-causing mutation in PKR2 receptor reveals a critical role of positive charges in the second intracellular loop for G-protein coupling and receptor trafficking |
| Q28570118 | Distinct functional roles of the metabotropic glutamate receptors 1 and 5 in the rat globus pallidus |
| Q36742217 | Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1). |
| Q37550019 | Diversity in arrestin function |
| Q34594482 | Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase |
| Q30439870 | Diversity of actions of GnRHs mediated by ligand-induced selective signaling |
| Q52655371 | Dopamine D1 receptor density in the mPFC responds to cognitive demands and receptor turnover contributes to general cognitive ability in mice. |
| Q37236711 | Dopamine D1 sensitivity in the prefrontal cortex predicts general cognitive abilities and is modulated by working memory training |
| Q24620977 | Dopamine D1-D2 receptor Heteromer-mediated calcium release is desensitized by D1 receptor occupancy with or without signal activation: dual functional regulation by G protein-coupled receptor kinase 2 |
| Q42652303 | Dopamine negatively modulates the NCA ion channels in C. elegans |
| Q34633358 | Dopamine receptor-coupling defect in hypertension |
| Q60141581 | Dopamine: Functions, Signaling, and Association with Neurological Diseases |
| Q35585071 | Dual mode of glucagon receptor internalization: role of PKCα, GRKs and β-arrestins |
| Q24314711 | Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association |
| Q50637362 | Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons. |
| Q37689400 | Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling |
| Q28505089 | Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor |
| Q36031734 | Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation |
| Q47364170 | E3 Ubiquitin Ligase RNF125 Activates Interleukin-36 Receptor Signaling and Contributes to Its Turnover. |
| Q36513459 | Effects of AT1 receptor-mediated endocytosis of extracellular Ang II on activation of nuclear factor-kappa B in proximal tubule cells |
| Q38357208 | Effects of repeated administration of baclofen to rats on GABAB receptor binding sites and subunit expression in the brain |
| Q92485760 | Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington's Disease: a Longitudinal PET Study |
| Q48469789 | Elongation factor 1A family regulates the recycling of the M4 muscarinic acetylcholine receptor |
| Q37225329 | Emerging targets in cancer management: role of the CXCL12/CXCR4 axis |
| Q41203921 | Endocannabinoid Modulation of Stimulus-Specific Adaptation in Inferior Colliculus Neurons of the Rat. |
| Q37405423 | Endocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses |
| Q40439525 | Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells |
| Q28581879 | Endosomal location of dopamine receptors in neuronal cell cytoplasm |
| Q36007033 | Endothelin induces rapid, dynamin-mediated budding of endothelial caveolae rich in ET-B. |
| Q24797337 | Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling |
| Q36692768 | Epidermal growth factor facilitates epinephrine inhibition of P2X7-receptor-mediated pore formation and apoptosis: a novel signaling network |
| Q42092237 | Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization |
| Q34360865 | Evaluation of the role of g protein-coupled receptor kinase 3 in desensitization of mouse odorant receptors in a Mammalian cell line and in olfactory sensory neurons |
| Q37324997 | Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney |
| Q34804942 | Expression Analysis of Visual Arrestin gene during Ocular Development of Olive Flounder (Paralichthys olivaceus). |
| Q27488257 | Expression and evolutionary divergence of the non-conventional olfactory receptor in four species of fig wasp associated with one species of fig |
| Q33291748 | Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells |
| Q33251201 | Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands. |
| Q46360447 | Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling. |
| Q21245556 | Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalization |
| Q35999789 | Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism. |
| Q36492513 | Function of non-visual arrestins in signaling and endocytosis of the gastrin-releasing peptide receptor (GRP receptor). |
| Q36282807 | Functional MT1 and MT2 melatonin receptors in mammals |
| Q41902981 | Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking |
| Q34210011 | Functional modulation of GABAB receptors by protein kinases and receptor trafficking |
| Q35264421 | Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance. |
| Q38017282 | Functional signaling biases in G protein-coupled receptors: Game Theory and receptor dynamics. |
| Q36666616 | Functional significance of GnRH and kisspeptin, and their cognate receptors in teleost reproduction |
| Q35212944 | G protein independent phosphorylation and internalization of the delta-opioid receptor |
| Q34639816 | G protein modulation of CaV2 voltage-gated calcium channels |
| Q35162044 | G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin. |
| Q30435176 | G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor |
| Q30309044 | G protein-coupled receptor kinase 4 gene variants in human essential hypertension |
| Q41904188 | G protein-coupled receptor kinase 6 (GRK6) selectively regulates endogenous secretin receptor responsiveness in NG108-15 cells |
| Q42263552 | G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice. |
| Q37200868 | G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor. |
| Q36914223 | G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interaction |
| Q36325794 | G protein-coupled receptor/arrestin3 modulation of the endocytic machinery |
| Q27023482 | G protein-coupled receptors: what a difference a 'partner' makes |
| Q38018652 | G-protein coupled receptor resensitization-appreciating the balancing act of receptor function. |
| Q36061579 | G-protein signaling: back to the future |
| Q34735704 | G-protein-coupled receptor phosphorylation: where, when and by whom |
| Q42440407 | GABA Transmission in the Nucleus Accumbens Is Altered after Withdrawal from Repeated Cocaine |
| Q37152694 | GPC-1, a G protein gamma-subunit, regulates olfactory adaptation in Caenorhabditis elegans |
| Q39020873 | GPCR Signaling and Trafficking: The Long and Short of It. |
| Q37396870 | GRK mythology: G-protein receptor kinases in cardiovascular disease |
| Q37347617 | GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail. |
| Q35660111 | GRK2 and β-arrestins in cardiovascular disease: Something old, something new. |
| Q90648916 | GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation |
| Q64252945 | GRKs and β-Arrestins: "Gatekeepers" of Mitochondrial Function in the Failing Heart |
| Q35767556 | Gene expression profiling of the cephalothorax and eyestalk in Penaeus monodon during ovarian maturation. |
| Q36103263 | Genetic Variations in the Serotonergic System Mediate a Combined, Weakened Response to SSRI Treatment: A Proposed Model(1,2) |
| Q40154290 | Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2, and response to niacin therapy |
| Q37117485 | Genetics of beta2-adrenergic receptors and the cardiopulmonary response to exercise |
| Q28067465 | Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes |
| Q47441819 | Gonadotropin regulation by pulsatile GnRH: Signaling and gene expression. |
| Q37529530 | HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism |
| Q39414464 | Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways |
| Q39455064 | Helix 8 plays a crucial role in bradykinin B(2) receptor trafficking and signaling |
| Q51677504 | Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells. |
| Q24791710 | Heterotrimeric G protein subunits are located on rat liver endosomes |
| Q34667584 | Heterotrimeric and unconventional GTP binding proteins in plant cell signaling. |
| Q36976659 | Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide |
| Q37420451 | Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important? |
| Q37629652 | Human dopamine receptor nanovesicles for gate-potential modulators in high-performance field-effect transistor biosensors |
| Q40249953 | Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization |
| Q30938337 | Human immunodeficiency virus type 1 entry inhibitors selected on living cells from a library of phage chemokines. |
| Q39694347 | Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain |
| Q33996731 | Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties |
| Q35589539 | Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase. |
| Q28481970 | Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor |
| Q36412846 | Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization |
| Q40601716 | Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site |
| Q39188583 | Identification of a novel protein-protein interaction motif mediating interaction of GPCR-associated sorting proteins with G protein-coupled receptors. |
| Q35604496 | Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling |
| Q36950107 | Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. |
| Q38758506 | Identification of human somatostatin receptor 2 domains involved in internalization and signaling in QGP-1 pancreatic neuroendocrine tumor cell line |
| Q90292354 | Imaging GPCR internalization using near-infrared Nebraska red-based reagents |
| Q44872466 | Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: evidence for phosphorylation-dependent and -independent regulation by G-protein-coupled receptor kinases. |
| Q36733839 | Immunohistochemical Localization of AT1a, AT1b, and AT2 Angiotensin II Receptor Subtypes in the Rat Adrenal, Pituitary, and Brain with a Perspective Commentary |
| Q42082080 | Impaired feedback regulation of the receptor activity and the myofilament Ca2+ sensitivity contributes to increased vascular reactiveness after subarachnoid hemorrhage |
| Q89684171 | In silico identification and assessment of insecticide target sites in the genome of the small hive beetle, Aethina tumida |
| Q27349439 | In vivo delta opioid receptor internalization controls behavioral effects of agonists |
| Q35047601 | Influence of agonist intrinsic activity on the desensitisation of beta2-adrenoceptor-mediated responses in mast cells |
| Q42703429 | Inhibition of protein phosphatase 2A activity by PI3Kγ regulates β-adrenergic receptor function |
| Q37629157 | Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase |
| Q37416728 | Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation |
| Q37068810 | Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases |
| Q34888305 | Intact MDM2 E3 ligase activity is required for the cytosolic localization and function of β-arrestin2 |
| Q38848001 | Integrating GRK2 and NFkappaB in the Pathophysiology of Cardiac Hypertrophy |
| Q33425860 | Interaction between CXCR4 and CCL20 pathways regulates tumor growth |
| Q28204278 | Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor |
| Q28573869 | Interactions of GIPC with Dopamine D2, D3but not D4Receptors Define a Novel Mode of Regulation of G Protein-coupled Receptors |
| Q33716607 | Interleukin-18 primes the oxidative burst of neutrophils in response to formyl-peptides: role of cytochrome b558 translocation and N-formyl peptide receptor endocytosis |
| Q37119883 | Internalization and desensitization of adenosine receptors |
| Q40650863 | Internalization and recycling of human μ opioid receptors expressed in Sf9 insect cells |
| Q33991193 | Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3. |
| Q24623433 | International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors |
| Q24643524 | International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states |
| Q36696159 | Intracellular ANG II directly induces in vitro transcription of TGF-beta1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors |
| Q35600402 | Investigation of the fate of type I angiotensin receptor after biased activation |
| Q40509065 | Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization. |
| Q34697009 | KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation. |
| Q42924464 | Kinetic diversity in G-protein-coupled receptor signalling |
| Q30477441 | Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo |
| Q33730592 | Ligand-directed signalling at beta-adrenoceptors |
| Q34154223 | Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance |
| Q24322961 | Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells |
| Q37031716 | Lipid raft-dependent glucagon-like peptide-2 receptor trafficking occurs independently of agonist-induced desensitization. |
| Q49798113 | Liraglutide Inhibits the Apoptosis of MC3T3-E1 Cells Induced by Serum Deprivation through cAMP/PKA/β-Catenin and PI3K/AKT/GSK3β Signaling Pathways |
| Q92431224 | Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway |
| Q35788055 | Long-acting beta 2-adrenoceptor agonists and exercise-induced asthma: lessons to guide us in the future |
| Q36184484 | Look before leaping: combined opioids may not be the rave |
| Q42211562 | Lysophosphatidylcholine-induced surface redistribution regulates signaling of the murine G protein-coupled receptor G2A. |
| Q46335711 | MAGI Proteins Regulate the Trafficking and Signaling of Corticotropin-Releasing Factor Receptor 1 via a Compensatory Mechanism. |
| Q27317076 | MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures |
| Q35037771 | Maintenance of homeostasis in the aging hypothalamus: the central and peripheral roles of succinate |
| Q37571541 | Mammalian olfactory receptors: pharmacology, G protein coupling and desensitization |
| Q58435171 | Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 |
| Q24305064 | Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2 |
| Q36161815 | Mechanisms for inhibition of P2 receptors signaling in neural cells |
| Q35147150 | Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+. |
| Q38363846 | Mechanisms of homologous and heterologous phosphorylation of FFA receptor 4 (GPR120): GRK6 and PKC mediate phosphorylation of Thr³⁴⁷, Ser³⁵⁰, and Ser³⁵⁷ in the C-terminal tail |
| Q37314365 | Mechanisms of pharmacogenomic effects of genetic variation within the cardiac adrenergic network in heart failure |
| Q33866666 | Mechanisms of regulation and function of G-protein-coupled receptor kinases |
| Q37692401 | Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors |
| Q47112398 | Melatonin as a potential inhibitory agent in head and neck cancer |
| Q34415636 | Membrane rafts and GnRH receptor signaling |
| Q37194670 | Membrane-tethered ligands are effective probes for exploring class B1 G protein-coupled receptor function |
| Q30441797 | Memory in receptor-ligand-mediated cell adhesion |
| Q48020126 | Methods for the Development of In Silico GPCR Models |
| Q39637973 | Methods to detect cell surface expression and constitutive activity of GPR6 |
| Q37610141 | Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery. |
| Q38459674 | Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling |
| Q24337593 | Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome |
| Q38007481 | Modulation of cell surface GABA(B) receptors by desensitization, trafficking and regulated degradation |
| Q37410471 | Modulation of opioid receptor function by protein-protein interactions |
| Q42463227 | Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. |
| Q37592198 | Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons |
| Q54115773 | Multiple Transceptors for Macro- and Micro-Nutrients Control Diverse Cellular Properties Through the PKA Pathway in Yeast: A Paradigm for the Rapidly Expanding World of Eukaryotic Nutrient Transceptors Up to Those in Human Cells. |
| Q38599397 | Multiple functions of G protein-coupled receptor kinases |
| Q92524582 | NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression |
| Q45938535 | Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation. |
| Q24320318 | Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor |
| Q41775962 | Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine. |
| Q33652453 | Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep: colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones. |
| Q38005033 | Neuroprotective roles of the P2Y(2) receptor. |
| Q35922475 | Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. |
| Q36107308 | Neutrophil reverse migration becomes transparent with zebrafish |
| Q37293326 | New frontiers in the intrarenal Renin-Angiotensin system: a critical review of classical and new paradigms |
| Q35109349 | New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II |
| Q42122607 | Non-invasive Optical Biosensor for Probing Cell Signaling. |
| Q39193250 | Noncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling |
| Q36513492 | Novel roles of intracrine angiotensin II and signalling mechanisms in kidney cells |
| Q36494441 | Novel signaling mechanisms of intracellular angiotensin II-induced NHE3 expression and activation in mouse proximal tubule cells |
| Q34282386 | Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis |
| Q36211468 | Once and future signaling: G protein-coupled receptor kinase control of neuronal sensitivity. |
| Q48413482 | Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions |
| Q53279466 | Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension. |
| Q28731227 | PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2 |
| Q37727180 | PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes |
| Q39150818 | Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence |
| Q26774991 | Pedunculopontine Gamma Band Activity and Development |
| Q37679197 | Pharmacological Profiles of Oligomerized μ-Opioid Receptors |
| Q37351558 | Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors |
| Q33784371 | Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor |
| Q89905655 | Pharmacotherapeutic management of co-morbid alcohol and opioid use |
| Q38766244 | Phoenixin Activates Immortalized GnRH and Kisspeptin Neurons Through the Novel Receptor GPR173. |
| Q24304439 | Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis |
| Q30400167 | Phosphorylation and Internalization of Lysophosphatidic Acid Receptors LPA1, LPA2, and LPA3. |
| Q40515487 | Phosphorylation and desensitization of the lysophosphatidic acid receptor LPA1. |
| Q41864683 | Phosphorylation and feedback regulation of metabotropic glutamate receptor 1 by calcium/calmodulin-dependent protein kinase II. |
| Q34016207 | Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis |
| Q30550026 | Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay |
| Q39972706 | Phosphorylation state of mu-opioid receptor determines the alternative recycling of receptor via Rab4 or Rab11 pathway |
| Q41923390 | Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons |
| Q38136643 | Physiology and pharmacology of the cardiovascular adrenergic system |
| Q37821307 | Physiopathology of splanchnic vasodilation in portal hypertension |
| Q34166099 | Plants: the latest model system for G-protein research |
| Q33848769 | Polarization of the yeast pheromone receptor requires its internalization but not actin-dependent secretion |
| Q35098633 | Porcine left atrial and sinoatrial 5-HT(4) receptor-induced responses: fading of the response and influence of development |
| Q37697146 | Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling |
| Q42837702 | Prolonged G(q) activity triggers fly rhodopsin endocytosis and degradation, and reduces photoreceptor sensitivity |
| Q53629015 | Protease-activated receptors modulate excitability of murine colonic smooth muscles by differential effects on interstitial cells. |
| Q89747342 | Protein expression of prenyltransferase subunits in postmortem schizophrenia dorsolateral prefrontal cortex |
| Q34126404 | Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin |
| Q24616083 | Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3 |
| Q44798722 | Rab GTPases Bind at a Common Site within the Angiotensin II Type I Receptor Carboxyl-Terminal Tail: Evidence that Rab4 Regulates Receptor Phosphorylation, Desensitization, and Resensitization |
| Q30417931 | Rab4 and Rab11 coordinately regulate the recycling of angiotensin II type I receptor as demonstrated by fluorescence resonance energy transfer microscopy |
| Q48282742 | Rab8 modulates metabotropic glutamate receptor subtype 1 intracellular trafficking and signaling in a protein kinase C-dependent manner |
| Q28571646 | Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis |
| Q45249983 | Rapid activity-driven SNARE-dependent trafficking of nicotinic receptors on somatic spines. |
| Q42503660 | Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor. |
| Q37179626 | Real-time monitoring of intracellular cAMP during acute ethanol exposure |
| Q38884341 | Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension |
| Q27006067 | Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs) |
| Q41832380 | Receptor desensitization and blockade of the suppressive effects of prostaglandin E2 and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes |
| Q34712523 | Receptor downregulation and desensitization enhance the information processing ability of signalling receptors |
| Q92798275 | Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks |
| Q33975451 | Receptors and effects of gut hormones in three osteoblastic cell lines |
| Q36245570 | Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. |
| Q36301741 | Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors. |
| Q36565441 | Regulation of Ca(V)2 calcium channels by G protein coupled receptors. |
| Q30010478 | Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins |
| Q35898711 | Regulation of N-Formyl Peptide Receptor Signaling and Trafficking by Arrestin-Src Kinase Interaction |
| Q35579681 | Regulation of alpha-1B adrenergic receptor localization, trafficking, function, and stability |
| Q36645435 | Regulation of mast cells by beta-agonists |
| Q41905591 | Regulation of membrane cholecystokinin-2 receptor by agonists enables classification of partial agonists as biased agonists. |
| Q35119377 | Regulation of muscarinic acetylcholine receptor signaling |
| Q36569620 | Regulation of synaptic transmission by ambient extracellular glutamate |
| Q37951309 | Regulation of β-adrenergic receptor function: an emphasis on receptor resensitization |
| Q35546495 | Regulation of β-adrenergic responses in airway smooth muscle |
| Q41807720 | Requirement for direct cross-talk between B1 and B2 kinin receptors for the proliferation of androgen-insensitive prostate cancer PC3 cells |
| Q28266829 | Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors |
| Q37398071 | RhoB plays an essential role in CXCR2 sorting decisions |
| Q35197367 | Role of Beta-arrestin 2 downstream of dopamine receptors in the Basal Ganglia. |
| Q33568279 | Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization. |
| Q33440398 | Role of G protein-coupled receptor kinase-2 in peroxisome proliferator-activated receptor gamma-mediated modulation of blood pressure and renal vascular reactivity in SHR. |
| Q37145537 | Role of PP1 in the regulation of Ca cycling in cardiac physiology and pathophysiology |
| Q36763812 | Role of Ubiquitination in Endocytic Trafficking of G‐Protein‐Coupled Receptors |
| Q35107385 | Role of c-Cbl carboxyl terminus in serotonin 5-HT2A receptor recycling and resensitization |
| Q34355891 | Role of caveolin 1 in AT1a receptor-mediated uptake of angiotensin II in the proximal tubule of the kidney. |
| Q37276968 | Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology |
| Q37329469 | Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation |
| Q48247517 | S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling |
| Q36953348 | SCF/c-kit transactivates CXCR4-serine 339 phosphorylation through G protein-coupled receptor kinase 6 and regulates cardiac stem cell migration |
| Q37640295 | SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling |
| Q41852598 | Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization |
| Q37210835 | Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands |
| Q36514681 | Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells |
| Q33642724 | Selective regulation of H1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells. |
| Q44330114 | Separation of mu-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. |
| Q36647024 | Serotonin receptor signaling and regulation via β-arrestins |
| Q33890786 | Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery |
| Q36932111 | Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation |
| Q30482316 | Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium |
| Q30677207 | Single Molecule Imaging Deciphers the Relation between Mobility and Signaling of a Prototypical G Protein-coupled Receptor in Living Cells |
| Q39998920 | Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling |
| Q89621229 | Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions |
| Q36203020 | Structural basis of ventricular remodeling: role of the myocyte. |
| Q35921707 | Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo |
| Q64945049 | Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma. |
| Q28362372 | Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors |
| Q27657193 | Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking |
| Q27681431 | Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli |
| Q93085849 | Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1 |
| Q37332439 | Subcellular trafficking of the TRH receptor: effect of phosphorylation |
| Q36528775 | Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A |
| Q34986708 | Sustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent manner |
| Q44940730 | Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter |
| Q26774663 | T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors. |
| Q33705761 | T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure |
| Q37553878 | TLR4-dependent internalization of CX3CR1 aggravates sepsis-induced immunoparalysis |
| Q38153376 | Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy |
| Q38230659 | Termination of immune activation: an essential component of healthy host immune responses. |
| Q50041957 | The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells |
| Q28582288 | The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis |
| Q48181601 | The Ancient Link between G-Protein-Coupled Receptors and C-Terminal Phospholipid Kinase Domains. |
| Q92020707 | The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors |
| Q39381430 | The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling |
| Q52880300 | The Function of G-Protein-Coupled Receptor-Regulatory Cascade in Southern House Mosquitoes (Diptera: Culicidae). |
| Q50851917 | The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway. |
| Q37702799 | The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease |
| Q40288125 | The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis |
| Q54109145 | The Orphan G Protein-coupled Receptor 75 Signaling is Activated by the Chemokine CCL5. |
| Q36029005 | The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors. |
| Q55402112 | The Protein Arginine Methyltransferase PRMT-5 Regulates SER-2 Tyramine Receptor-Mediated Behaviors in Caenorhabditis elegans. |
| Q37501416 | The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression |
| Q24337078 | The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization |
| Q37151762 | The conformational signature of β-arrestin2 predicts its trafficking and signalling functions. |
| Q24323133 | The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization |
| Q34259695 | The dopamine D2 receptor gene in lamprey, its expression in the striatum and cellular effects of D2 receptor activation |
| Q36831073 | The downstream regulation of chemokine receptor signalling: implications for atherosclerosis |
| Q35047674 | The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology |
| Q40009569 | The internalization of the M2 and M4 muscarinic acetylcholine receptors involves distinct subsets of small G-proteins. |
| Q24306837 | The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor |
| Q24675679 | The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation |
| Q37131419 | The origins of diversity and specificity in g protein-coupled receptor signaling |
| Q27010675 | The pathophysiology of fragile X (and what it teaches us about synapses) |
| Q36224586 | The protein LJM 111 from Lutzomyia longipalpis salivary gland extract (SGE) accounts for the SGE-inhibitory effects upon inflammatory parameters in experimental arthritis model |
| Q28478627 | The rates of protein synthesis and degradation account for the differential response of neurons to spaced and massed training protocols |
| Q36620923 | The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells |
| Q30459130 | The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology |
| Q30506209 | The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment |
| Q36455999 | The role of palmitoylation in directing dopamine D1 receptor internalization through selective endocytic routes |
| Q36550825 | The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin association |
| Q24650706 | The rush to adrenaline: drugs in sport acting on the beta-adrenergic system |
| Q40463546 | The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. |
| Q34134468 | The sympathetic nervous system induces a metastatic switch in primary breast cancer |
| Q40032446 | The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation |
| Q34546941 | The timing of endocytosis after activation of a G-protein-coupled receptor in a sensory neuron |
| Q59807304 | Therapeutic Targets for Treatment of Heart Failure: Focus on GRKs and β-Arrestins Affecting βAR Signaling |
| Q41928212 | Transcriptomic Sequencing Reveals a Set of Unique Genes Activated by Butyrate-Induced Histone Modification |
| Q42742576 | Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12 |
| Q34823587 | Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES |
| Q24657919 | Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes |
| Q35569258 | Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting. |
| Q34099132 | Unconventional homologous internalization of the angiotensin II type-1 receptor induced by G-protein-independent signals |
| Q35808585 | Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors |
| Q53592953 | Up-regulation of Metabotropic glutamate receptor 3 (mGluR3) in rat fibrosis and cirrhosis model of persistent hypoxic condition. |
| Q34175227 | Using high resolution imaging to determine trafficking of corticotropin-releasing factor receptors in noradrenergic neurons of the rat locus coeruleus. |
| Q90664806 | Varying Stimulation Parameters to Improve Cortical Plasticity Generated by VNS-tone Pairing |
| Q28575154 | Visualization of a functionally enhanced GFP-tagged galanin R2 receptor in PC12 cells: constitutive and ligand-induced internalization |
| Q41535363 | Visualization of ligand-induced dopamine D2S and D2L receptor internalization by TIRF microscopy |
| Q28241229 | Visualization of the pH-dependent dynamic distribution of G2A in living cells |
| Q36567891 | Voltage regulates adrenergic receptor function |
| Q36928258 | Whole blood impedance aggregometry as a biomarker for the diagnosis and prognosis of severe sepsis |
| Q33840022 | beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation |
| Q24556620 | beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform |
| Q40720739 | mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. |
| Q27311117 | α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization |
| Q35426493 | β-Arrestin-dependent deactivation of mouse melanopsin. |
| Q39992588 | β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo |
| Q37421052 | βArrestins in cardiac G protein-coupled receptor signaling and function: partners in crime or "good cop, bad cop"? |
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