Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling

scientific article published on 05 May 2015

Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/ME.2015-1091
P932PMC publication ID5414738
P698PubMed publication ID25942107
P5875ResearchGate publication ID275894827

P2093author name stringStephen S G Ferguson
Cornelia Walther
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Interactions with PDZ domain proteins PIST/GOPC and PDZK1 regulate intracellular sorting of the somatostatin receptor subtype 5.Q40398562
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptorsQ40442171
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Heterotrimeric G proteins.Q41099712
Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalizationQ41238228
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Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.Q41985832
Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).Q42061332
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AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.Q43845849
Inhibition of the dopamine D1 receptor signaling by PSD-95.Q37112269
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GPCR signaling along the endocytic pathwayQ37141950
Management of osteoporosis among the elderly with other chronic medical conditionsQ37156112
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.Q37201202
Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancerQ37224229
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complexQ37273521
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.Q37318691
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma developmentQ37329206
Role of AKAP79/150 protein in β1-adrenergic receptor trafficking and signaling in mammalian cellsQ37333740
Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptorQ37337832
A chemical-genetic approach to study G protein regulation of beta cell function in vivo.Q37399580
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetesQ37443837
Sorting of β1-adrenergic receptors is mediated by pathways that are either dependent on or independent of type I PDZ, protein kinase A (PKA), and SAP97.Q37511764
Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments.Q37583445
GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling.Q37594994
Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.Q37610141
GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologiesQ37670210
Regulation of GPCR signal networks via membrane trafficking.Q37775131
Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?Q37800215
G protein-coupled receptors: mutations and endocrine diseasesQ37837505
Refining efficacy: allosterism and bias in G protein-coupled receptor signaling.Q37922659
GPCR-interacting proteins, major players of GPCR functionQ37930224
PDZ domains: the building blocks regulating tumorigenesisQ37939947
From parathyroid hormone to cytosolic Ca2+ signals.Q37977175
Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptorsQ38014954
Signalling bias in new drug discovery: detection, quantification and therapeutic impact.Q38081692
Arrestins: role in the desensitization, sequestration, and vesicular trafficking of G protein-coupled receptorsQ38114212
Emerging paradigms in GPCR allostery: implications for drug discoveryQ38125563
CRF system and mood disordersQ38141409
Biasing GPCR signaling from inside.Q38182817
Extensive shape shifting underlies functional versatility of arrestinsQ38200331
Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.Q38209355
Advances in G protein-coupled receptor allostery: from function to structureQ38233848
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.Q38302685
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)814-830
P577publication date2015-05-05
P13046publication type of scholarly workreview articleQ7318358
P1433published inMolecular EndocrinologyQ3319475
P1476titleMinireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling
P478volume29

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