| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Vsevolod V. Gurevich | Q42173663 |
| Eugenia V Gurevich | Q91734876 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 105-11 | |
| P577 | publication date | 2004-02-01 | |
| P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
| P1476 | title | The molecular acrobatics of arrestin activation | |
| P478 | volume | 25 |
| Q36586576 | A boolean network modelling of receptor mosaics relevance of topology and cooperativity |
| Q28569075 | A dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin binding |
| Q36691842 | A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction |
| Q40262832 | A model for the solution structure of the rod arrestin tetramer |
| Q42290882 | A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling |
| Q35156778 | A single mutation in arrestin-2 prevents ERK1/2 activation by reducing c-Raf1 binding. |
| Q33208189 | Activation-dependent conformational changes in {beta}-arrestin 2. |
| Q57752440 | Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin |
| Q35213182 | Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons |
| Q42576987 | An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production |
| Q26785358 | Analyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKs |
| Q33212027 | Application of functional genomic technologies in a mouse model of retinal degeneration |
| Q42976243 | Arrestin binding to calmodulin: a direct interaction between two ubiquitous signaling proteins |
| Q36953762 | Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences |
| Q42668381 | Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors |
| Q40159254 | Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity. |
| Q37415694 | Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding |
| Q41981772 | Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains. |
| Q42385786 | Arrestin-dependent activation of JNK family kinases |
| Q36779793 | Arrestin-dependent but G-protein coupled receptor kinase-independent uncoupling of D2-dopamine receptors |
| Q60303237 | Arrestin-mediated signaling: Is there a controversy? |
| Q34606311 | Arrestin-rhodopsin binding stoichiometry in isolated rod outer segment membranes depends on the percentage of activated receptors |
| Q39182855 | Arresting the Development of Addiction: The Role of β-Arrestin 2 in Drug Abuse. |
| Q36510471 | Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia |
| Q35077008 | Arrestins regulate cell spreading and motility via focal adhesion dynamics |
| Q93333139 | Arrestins: Introducing Signaling Bias Into Multifunctional Proteins |
| Q49908026 | Arrestins: structural disorder creates rich functionality. |
| Q21184142 | Arrestins: ubiquitous regulators of cellular signaling pathways |
| Q90632604 | Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey |
| Q38320656 | Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor |
| Q24321629 | Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling |
| Q29616793 | Beta-arrestins and cell signaling |
| Q38311702 | Beyond traditional pharmacology: new tools and approaches |
| Q90575731 | Biased GPCR signaling: Possible mechanisms and inherent limitations |
| Q36790136 | Binding between a distal C-terminus fragment of cannabinoid receptor 1 and arrestin-2. |
| Q35626307 | C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor |
| Q39597237 | CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. |
| Q47348549 | Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor |
| Q47073148 | Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae |
| Q36389593 | Conformation of receptor-bound visual arrestin |
| Q90281542 | Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms |
| Q45047394 | Conformational changes in the phosphorylated C-terminal domain of rhodopsin during rhodopsin arrestin interactions |
| Q35558790 | Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process. |
| Q37174339 | Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding |
| Q34551853 | Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation. |
| Q36796795 | Critical role of the central 139-loop in stability and binding selectivity of arrestin-1. |
| Q64090244 | Critical role of the finger loop in arrestin binding to the receptors |
| Q27666519 | Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes |
| Q37735949 | Custom-designed proteins as novel therapeutic tools? The case of arrestins |
| Q46689397 | Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants. |
| Q41991082 | Desensitization and internalization of endothelin receptor A: impact of G protein-coupled receptor kinase 2 (GRK2)-mediated phosphorylation |
| Q34596638 | Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin |
| Q42509112 | Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors |
| Q41786424 | Direct interactions between calcitonin-like receptor (CLR) and CGRP-receptor component protein (RCP) regulate CGRP receptor signaling |
| Q64077238 | Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation |
| Q28118801 | Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking |
| Q39938423 | Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization |
| Q38316559 | Dynamics of arrestin-rhodopsin interactions: acidic phospholipids enable binding of arrestin to purified rhodopsin in detergent |
| Q45182666 | Dynamics of arrestin-rhodopsin interactions: arrestin and retinal release are directly linked events |
| Q35652316 | Each rhodopsin molecule binds its own arrestin |
| Q41894869 | Elucidation of inositol hexaphosphate and heparin interaction sites and conformational changes in arrestin-1 by solution nuclear magnetic resonance. |
| Q42159390 | Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation |
| Q42394084 | Enhanced phosphorylation-independent arrestins and gene therapy |
| Q38200331 | Extensive shape shifting underlies functional versatility of arrestins |
| Q35085144 | Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins |
| Q34105948 | Functional comparisons of visual arrestins in rod photoreceptors of transgenic mice |
| Q34544364 | Functional competence of a partially engaged GPCR-β-arrestin complex |
| Q50985256 | Functional role of the three conserved cysteines in the N domain of visual arrestin-1. |
| Q47740257 | G Protein-Coupled Receptor Kinases in the Inflammatory Response and Signaling. |
| Q35536256 | G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs). |
| Q38834292 | G protein-coupled receptor kinases as regulators of dopamine receptor functions |
| Q35621624 | G protein-coupled receptor kinases: more than just kinases and not only for GPCRs |
| Q35065927 | G protein-coupled receptors--recent advances |
| Q40281519 | G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer |
| Q64228935 | GPCR Signaling Regulation: The Role of GRKs and Arrestins |
| Q37058647 | GPCR monomers and oligomers: it takes all kinds |
| Q90148445 | Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor |
| Q46731935 | Homo- and hetero-oligomerization of beta-arrestins in living cells |
| Q37120246 | How and why do GPCRs dimerize? |
| Q28646207 | How genetic errors in GPCRs affect their function: Possible therapeutic strategies |
| Q33947214 | Identification of receptor binding-induced conformational changes in non-visual arrestins |
| Q35005851 | Interaction of Arrestin with Enolase1 in Photoreceptors |
| Q36545558 | Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin |
| Q40052743 | Isotope labeling of mammalian GPCRs in HEK293 cells and characterization of the C-terminus of bovine rhodopsin by high resolution liquid NMR spectroscopy |
| Q37365027 | Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions |
| Q36215950 | Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins |
| Q33272818 | Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays |
| Q38318691 | Methodological advances: the unsung heroes of the GPCR structural revolution. |
| Q38459674 | Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling |
| Q47218417 | Molecular Defects of the Disease-Causing Human Arrestin-1 C147F Mutant |
| Q47255137 | Molecular Mechanisms of GPCR Signaling: A Structural Perspective |
| Q36599592 | Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. |
| Q96577256 | Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor |
| Q64895618 | Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation. |
| Q34489038 | Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding |
| Q35927616 | Mu-opioid receptor desensitization: is morphine different? |
| Q34580426 | Mutation of three residues in the third intracellular loop of the dopamine D2 receptor creates an internalization-defective receptor |
| Q39009770 | Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes |
| Q40141701 | N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins. |
| Q24320318 | Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor |
| Q36211468 | Once and future signaling: G protein-coupled receptor kinase control of neuronal sensitivity. |
| Q30839922 | Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association |
| Q38274970 | Overview of different mechanisms of arrestin-mediated signaling |
| Q94388687 | Paradigm Shift is the Normal State of Pharmacology |
| Q36059730 | Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. |
| Q43071964 | Photoreceptor damage induced by low-intensity light: model of retinal degeneration in mammals |
| Q33598499 | Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration |
| Q42044999 | Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant |
| Q37198765 | Rapid recycling of beta-adrenergic receptors is dependent on the actin cytoskeleton and myosin Vb. |
| Q47734938 | Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors |
| Q34480207 | Rhodopsin self-associates in asolectin liposomes |
| Q37178682 | Rich tapestry of G protein-coupled receptor signaling and regulatory mechanisms |
| Q34708925 | Robust self-association is a common feature of mammalian visual arrestin-1. |
| Q38112747 | Role of CGRP-receptor component protein (RCP) in CLR/RAMP function |
| Q42026440 | Role of Ca2+/calmodulin-dependent protein kinase II in Drosophila photoreceptors |
| Q34335080 | Role of beta-arrestin 1 in the metastatic progression of colorectal cancer |
| Q35841895 | Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors. |
| Q36197653 | Role of rhodopsin and arrestin phosphorylation in retinal degeneration of Drosophila |
| Q33855672 | Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling. |
| Q40331167 | Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation |
| Q38329810 | Roles of phosphorylation-dependent and -independent mechanisms in the regulation of M1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 in hippocampal neurons. |
| Q53283601 | S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence. |
| Q41852598 | Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization |
| Q36003914 | Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant |
| Q89662702 | Site-directed labeling of β-arrestin with monobromobimane for measuring their interaction with G protein-coupled receptors |
| Q28541546 | Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract |
| Q34581973 | Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa. |
| Q64926886 | Structural Basis of Arrestin-Dependent Signal Transduction. |
| Q38114211 | Structural determinants of arrestin functions |
| Q40383376 | Structural evidence for the role of polar core residue Arg175 in arrestin activation |
| Q59082343 | Structural insights into G-protein-coupled receptor allostery |
| Q27677473 | Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide |
| Q38016028 | Synthetic biology with surgical precision: targeted reengineering of signaling proteins |
| Q36992906 | The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis |
| Q38874828 | The Multiple Waves of Cannabinoid 1 Receptor Signaling |
| Q28570207 | The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2 |
| Q37903343 | The cytoplasmic rhodopsin-protein interface: potential for drug discovery |
| Q34103312 | The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation |
| Q35387361 | The functional cycle of visual arrestins in photoreceptor cells |
| Q24306837 | The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor |
| Q35839976 | The origin and evolution of G protein-coupled receptor kinases |
| Q42407943 | The rhodopsin-arrestin-1 interaction in bicelles. |
| Q24657537 | The structural basis of arrestin-mediated regulation of G-protein-coupled receptors |
| Q59807304 | Therapeutic Targets for Treatment of Heart Failure: Focus on GRKs and β-Arrestins Affecting βAR Signaling |
| Q42098997 | Therapeutic potential of small molecules and engineered proteins |
| Q36141465 | Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse |
| Q28246395 | Transduction of receptor signals by beta-arrestins |
| Q36363295 | Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment |
| Q36663074 | Type 1 angiotensin receptor pharmacology: signaling beyond G proteins. |
| Q42173591 | Ubiquitin ligase parkin promotes Mdm2-arrestin interaction but inhibits arrestin ubiquitination |
| Q36228675 | Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family |
| Q36726921 | Visual arrestin binding to microtubules involves a distinct conformational change |
| Q36915521 | Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina |
| Q28244290 | Visualization of arrestin recruitment by a G-protein-coupled receptor |
| Q36083423 | ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands. |
| Q38074124 | β-Arrestin-kinase scaffolds: turn them on or turn them off? |
| Q35175384 | β-Arrestin-mediated receptor trafficking and signal transduction |
| Q24297887 | β-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development |
| Q92350653 | β-arrestin2 alleviates L-dopa-induced dyskinesia via lower D1R activity in Parkinson's rats |
| Q38167642 | β-arrestins and G protein-coupled receptor trafficking |
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