Role of PDZ Proteins in Regulating Trafficking, Signaling, and Function of GPCRs: Means, Motif, and Opportunity

scientific article published on January 1, 2011

Role of PDZ Proteins in Regulating Trafficking, Signaling, and Function of GPCRs: Means, Motif, and Opportunity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/B978-0-12-385952-5.00003-8
P953full work available online athttps://api.elsevier.com/content/article/PII:B9780123859525000038?httpAccept=text/plain
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https://doi.org/10.1016/b978-0-12-385952-5.00003-8
https://europepmc.org/articles/PMC4968410
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P3181OpenCitations bibliographic resource ID2433524
P932PMC publication ID4968410
P698PubMed publication ID21907913
P5875ResearchGate publication ID51639372

P50authorMark von ZastrowQ87720344
P2093author name stringGuillermo Romero
Peter A. Friedman
P2860cites workGIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIPQ22003946
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptorsQ22007971
Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteinsQ22008754
Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding proteinQ24290612
A Golgi-associated PDZ Domain Protein Modulates Cystic Fibrosis Transmembrane Regulator Plasma Membrane ExpressionQ24291900
Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102Q24293430
SNX27 mediates PDZ-directed sorting from endosomes to the plasma membraneQ24297153
Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteinsQ24297397
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Q24297673
Direct interaction between NHERF1 and Frizzled regulates β-catenin signalingQ24298046
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchangeQ24310009
Cloning and Characterization of BAI-Associated Protein 1: A PDZ Domain-Containing Protein That Interacts with BAI1Q24310654
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) DomainQ24311627
NHERF1 mutations and responsiveness of renal parathyroid hormoneQ24311831
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteinsQ24316901
Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteinsQ24318774
Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factorQ24323161
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptorQ24323946
Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activityQ24515074
PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7Q24536819
NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activationQ24563311
MAGI-3 regulates LPA-induced activation of Erk and RhoAQ24680474
Interaction of neuronal nitric oxide synthase with alpha1-adrenergic receptor subtypes in transfected HEK-293 cellsQ24804126
Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complexQ27618075
Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognitionQ27622377
Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domainsQ27631751
Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formationQ27638891
Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2.Q36503006
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of FrizzledQ27642624
Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZQ27732927
Crystal structure of a PDZ domainQ27733300
The Wnt signaling pathway in development and diseaseQ27861019
PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptorQ28139681
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteinsQ28139757
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteinsQ28141190
G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interactionQ28142079
Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responsesQ28144632
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptorQ28145098
Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesinsQ28201977
Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95Q28204855
GIPC Binds to the Human Lutropin Receptor (hLHR) through an Unusual PDZ Domain Binding Motif, and It Regulates the Sorting of the Internalized Human Choriogonadotropin and the Density of Cell Surface hLHRQ28204866
Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signallingQ28205878
The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulationQ28206397
Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CALQ28211647
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzledQ28214292
Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rateQ28217140
Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50)Q28218864
Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1Q28243045
Ezrin induces long-range interdomain allostery in the scaffolding protein NHERF1Q28251491
kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteinsQ28255347
MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and LtapQ28266828
Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domainsQ28278085
A human exchange factor for ARF contains Sec7- and pleckstrin-homology domainsQ28298548
Homer: a protein that selectively binds metabotropic glutamate receptorsQ28305877
Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wastingQ28510488
The C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathwaysQ28510674
Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein associationQ28568130
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases inQ28573532
Interactions of GIPC with Dopamine D2, D3but not D4Receptors Define a Novel Mode of Regulation of G Protein-coupled ReceptorsQ28573869
The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signalQ28574773
PICK1 interacts with and regulates PKC phosphorylation of mGLUR7Q28576999
5-HT2C and GABAB receptors influence handling-induced convulsion severity in chromosome 4 congenic and DBA/2J background strain miceQ36569692
Biologic actions and therapeutic potential of the proglucagon-derived peptidesQ36575421
Serotonin receptor signaling and regulation via β-arrestinsQ36647024
Catching a GEF by its tailQ36663439
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.Q37269189
Developmental roles for Homer: more than just a pretty scaffold.Q37338392
Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF)Q37382049
Metabotropic glutamate receptors: physiology, pharmacology, and diseaseQ37670222
GABAB receptor coupling to G-proteins and ion channelsQ37775207
Pharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinomaQ39635094
Identification of a novel region of the GABA(B2) C-terminus that regulates surface expression and neuronal targeting of the GABA(B) receptor.Q39872020
NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin bindingQ39888299
The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signalingQ39937859
The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxisQ39945961
Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networkingQ40196135
GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and functionQ40201003
Cargo regulates clathrin-coated pit dynamicsQ40224212
The post-endocytotic fate of the gonadotropin receptors is an important determinant of the desensitization of gonadotropin responsesQ40436869
Stimulation by parathyroid hormone of a NHERF-1-assembled complex consisting of the parathyroid hormone I receptor, phospholipase Cbeta, and actin increases intracellular calcium in opossum kidney cellsQ40575101
Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recyclingQ40778023
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.Q40984747
Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cellsQ41181779
Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell linesQ41328757
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.Q41412781
Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3',5'-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cellsQ41511689
Parathyroid hormone induces protein kinase C but not adenylate cyclase in adult cardiomyocytes and regulates cyclic AMP levels via protein kinase C-dependent phosphodiesterase activityQ42821868
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).Q44550523
Receptors specific for the carboxyl-terminal region of parathyroid hormone on bone-derived cells: determinants of ligand binding and bioactivityQ45206354
Effect of parathyroid hormone on human T cell activationQ46159294
Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons.Q46472740
The PDZ protein mupp1 promotes Gi coupling and signaling of the Mt1 melatonin receptorQ46672501
Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activityQ46819209
The effect of RGS12 on PDGFbeta receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cellsQ46958948
Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia.Q47073501
The role of protein interaction motifs in regulating the polarity and clustering of the metabotropic glutamate receptor mGluR1a.Q48456338
Mechanisms of β-Adrenergic Receptor Desensitization and ResensitizationQ48609403
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptorsQ51819583
The DIX domain targets dishevelled to actin stress fibres and vesicular membranesQ57800361
Parathyroid hormone stimulates protein kinase C but not adenylate cyclase in mouse epidermal keratinocytesQ67485866
Parathyroid hormone: an endogenous modulator of cardiac calcium channelsQ68266726
The roles of calcium and cyclic AMP in the stimulatory action of parathyroid hormone on thymic lymphocyte proliferationQ68638293
Parathyroid hormone stimulation of mitosis in rat thymic lymphocytes is independent of cyclic AMPQ69837872
Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase CQ70824012
Localization of BAI-associated protein1/membrane-associated guanylate kinase-1 at adherens junctions in normal rat kidney cells: polarized targeting mediated by the carboxyl-terminal PDZ domainsQ73134381
G protein-coupled receptor kinasesQ77366588
Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domainQ28577053
The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neuronsQ28583632
Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domainsQ28591070
Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammalsQ28591957
Recognition of unique carboxyl-terminal motifs by distinct PDZ domainsQ29547580
WNT and beta-catenin signalling: diseases and therapiesQ29616159
Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP.Q30477376
Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7Q30484745
PICK1 uncoupling from mGluR7a causes absence-like seizuresQ30491105
CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signalingQ30494303
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesisQ30494322
Formation of nNOS/PSD-95 PDZ dimer requires a preformed beta-finger structure from the nNOS PDZ domain.Q30616861
Identification of a specific inhibitor of the dishevelled PDZ domainQ33227576
Convergent and divergent ligand specificity among PDZ domains of the LAP and zonula occludens (ZO) families.Q33245309
MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channelsQ33258159
Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor-mediated transcriptionQ33345147
A specificity map for the PDZ domain familyQ33373127
P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2Q33841106
Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.Q33893544
Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits.Q34094401
Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1.Q34346382
The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation.Q34409674
The neuronal nitric oxide synthase PDZ motif binds to -G(D,E)XV* carboxyterminal sequences.Q34430352
Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormoneQ34555940
G-protein-coupled receptors for neurotransmitter amino acids: C-terminal tails, crowded signalosomesQ34634508
MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.Q34672741
The Frizzled family of unconventional G-protein-coupled receptorsQ34691416
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signalingQ35011307
The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signallingQ35124049
Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stabilityQ35128324
Physiological actions of regulators of G-protein signaling (RGS) proteinsQ35579616
Parathyroid hormone secretion and action: evidence for discrete receptors for the carboxyl-terminal region and related biological actions of carboxyl- terminal ligandsQ36028995
Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1Q36099426
The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity.Q36349480
Deletions of genes encoding calcitonin/alpha-CGRP, amylin and calcitonin receptor have given new and unexpected insights into the function of calcitonin receptors and calcitonin receptor-like receptors in boneQ36468850
P407language of work or nameEnglishQ1860
P921main subjectsignal transductionQ828130
G protein-coupled receptorQ38173
P304page(s)279-314
P577publication date2011-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inAdvances in PharmacologyQ15753809
P1476titleRole of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity
Role of PDZ Proteins in Regulating Trafficking, Signaling, and Function of GPCRs: Means, Motif, and Opportunity
P478volume62

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cites work (P2860)
Q36987597Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling
Q36098021Arrestin Scaffolds NHERF1 to the P2Y12 Receptor to Regulate Receptor Internalization
Q39267607Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks
Q64097803Biased Signaling and Allosteric Modulation at the FSHR
Q39006035Biochemical Large-Scale Interaction Analysis of Murine Olfactory Receptors and Associated Signaling Proteins with Post-Synaptic Density 95, Drosophila Discs Large, Zona-Occludens 1 (PDZ) Domains
Q38024032Calcium-dependent networks in dopamine-glutamate interaction: the role of postsynaptic scaffolding proteins.
Q26865657Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
Q35468530Computational design of selective peptides to discriminate between similar PDZ domains in an oncogenic pathway
Q36463629Desensitization, Trafficking, and Resensitization of the Pituitary Thyrotropin-Releasing Hormone Receptor
Q39198714Differential Endosomal Sorting of a Novel P2Y12 Purinoreceptor Mutant
Q26784027Direct and Propagated Effects of Small Molecules on Protein-Protein Interaction Networks
Q35875551Disruption of β-catenin binding to parathyroid hormone (PTH) receptor inhibits PTH-stimulated ERK1/2 activation.
Q37285415Distinct G protein-coupled receptor recycling pathways allow spatial control of downstream G protein signaling.
Q33692637Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells
Q36392890EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration
Q44778310Effective Attenuation of Adenosine A1R Signaling by Neurabin Requires Oligomerization of Neurabin
Q36097909Ezrin-anchored Protein Kinase A Coordinates Phosphorylation-dependent Disassembly of a NHERF1 Ternary Complex to Regulate Hormone-sensitive Phosphate Transport
Q26822675Fine-tuning multiprotein complexes using small molecules
Q38981514G protein-coupled receptor 30 (GPR30) forms a plasma membrane complex with membrane-associated guanylate kinases (MAGUKs) and protein kinase A-anchoring protein 5 (AKAP5) that constitutively inhibits cAMP production
Q27023482G protein-coupled receptors: what a difference a 'partner' makes
Q35069685G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus.
Q90423778Homologous Regulation of Mu Opioid Receptor Recycling by G βγ , Protein Kinase C, and Receptor Phosphorylation
Q33623314Investigating signaling consequences of GPCR trafficking in the endocytic pathway
Q41001463Ixazomib enhances parathyroid hormone-induced β-catenin/T-cell factor signaling by dissociating β-catenin from the parathyroid hormone receptor
Q27006957Kir3 channel signaling complexes: focus on opioid receptor signaling
Q46335711MAGI Proteins Regulate the Trafficking and Signaling of Corticotropin-Releasing Factor Receptor 1 via a Compensatory Mechanism.
Q35814372MAS C-Terminal Tail Interacting Proteins Identified by Mass Spectrometry- Based Proteomic Approach
Q38459674Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling
Q27676679Molecular Analysis of the Prostacyclin Receptor’s Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1
Q64113057Molecular evolutionary and structural analysis of familial exudative vitreoretinopathy associated FZD4 gene
Q38077232Molecular mechanisms of platelet P2Y12 receptor regulation
Q34559903Mpdz expression in the caudolateral substantia nigra pars reticulata is crucially involved in alcohol withdrawal
Q36910196NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells
Q33931148NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol
Q37719842Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption.
Q54977622Novel paradigms governing β1-adrenergic receptor trafficking in primary adult rat cardiac myocytes.
Q36135269PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli
Q39148389Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders
Q92304554Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor
Q37661312Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits.
Q38521179Postendocytic Sorting of Adrenergic and Opioid Receptors: New Mechanisms and Functions.
Q33603020Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation
Q38571588RGS proteins destroy spare receptors: Effects of GPCR-interacting proteins and signal deamplification on measurements of GPCR agonist potency
Q38060605Regulated GPCR Trafficking to the Plasma Membrane: General Issues and the CCR5 Chemokine Receptor Example
Q90399815Regulation of G protein-coupled receptor signaling by plasma membrane organization and endocytosis
Q92043547Regulation of Somatostatin Receptor 2 Trafficking by C-Tail Motifs and the Retromer
Q36779623Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs)
Q30546283Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch.
Q90425973Scribble co-operatively binds multiple α1D-adrenergic receptor C-terminal PDZ ligands
Q44343075Sequence-Specific Regulation of Endocytic Lifetimes Modulates Arrestin-Mediated Signaling at the µ Opioid Receptor.
Q30594792Src regulates sequence-dependent beta-2 adrenergic receptor recycling via cortactin phosphorylation.
Q34735823Stabilization of the angiotensin-(1–7) receptor Mas through interaction with PSD95
Q51011881Synapse formation changes the rules for desensitization of PKC translocation in Aplysia
Q36202656Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry
Q36760030Synergistic Effect of the PDZ and p85β-Binding Domains of the NS1 Protein on Virulence of an Avian H5N1 Influenza A Virus
Q92545761TMEM88 Inhibits Wnt Signaling by Promoting Wnt Signalosome Localization to Multivesicular Bodies
Q90529594Targeting of G-protein coupled receptors in sepsis
Q36184681The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity.
Q27314709The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization
Q28478627The rates of protein synthesis and degradation account for the differential response of neurons to spaced and massed training protocols
Q30409921The surprising dynamics of scaffolding proteins.
Q26783929Trafficking regulates the subcellular distribution of voltage-gated sodium channels in primary sensory neurons
Q40550018Visualizing and quantitating sequence-dependent GPCR recycling

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