scholarly article | Q13442814 |
P50 | author | Martin J. Lohse | Q102058 |
Tiziana de Filippis | Q117206761 | ||
Luca Persani | Q42816787 | ||
Carlo Tacchetti | Q56670600 | ||
Davide Calebiro | Q57014481 | ||
Maria Cristina Gagliani | Q57319998 | ||
Viacheslav O. Nikolaev | Q59832454 | ||
P2093 | author name string | Christian Dees | |
P2860 | cites work | Theoretical analyses of the functioning of the high- and low-Km cyclic nucleotide phosphodiesterases in the regulation of the concentration of adenosine 3′,5′-cyclic monophosphate in animal cells | Q72863212 |
The localization and activity of cAMP-dependent protein kinase affect cell cycle progression in thyroid cells | Q73316766 | ||
A genetically encoded, fluorescent indicator for cyclic AMP in living cells | Q73323788 | ||
Fluorescent sensors for rapid monitoring of intracellular cGMP | Q82043755 | ||
Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway | Q24298340 | ||
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. | Q24336212 | ||
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias | Q24337832 | ||
Efficient selection for high-expression transfectants with a novel eukaryotic vector | Q27860810 | ||
Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome | Q27935159 | ||
Expression of multiple adenylyl cyclase isoforms in human and dog thyroid | Q28143380 | ||
Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins | Q28237045 | ||
G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization | Q28276743 | ||
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid | Q28512822 | ||
G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes | Q28566417 | ||
Molecular cloning, characterization, and dynamics of rat formiminotransferase cyclodeaminase, a Golgi-associated 58-kDa protein | Q28584156 | ||
AKAP signalling complexes: focal points in space and time | Q29618533 | ||
Dynasore, a cell-permeable inhibitor of dynamin | Q29619881 | ||
Seven-transmembrane receptors | Q29619896 | ||
The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth* | Q30009787 | ||
PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases | Q30480533 | ||
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks | Q30489597 | ||
Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator | Q30497812 | ||
Adenylyl cyclase co-distribution with the CaBPs, calbindin-D28 and calretinin, varies with cell type: assessment with the fluorescent dye, BODIPY forskolin, in enteric ganglia | Q32060541 | ||
The human thyrotropin receptor is predominantly internalized by beta-arrestin 2. | Q33235338 | ||
Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice | Q33332135 | ||
cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists | Q33617881 | ||
A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell | Q33949069 | ||
Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses | Q33984279 | ||
The expression of the thyroid-stimulating hormone (TSH) receptor and the cAMP-dependent protein kinase RII beta regulatory subunit confers TSH-cAMP-dependent growth to mouse fibroblasts | Q34220128 | ||
Fluorescence ratio imaging of cyclic AMP in single cells | Q41695021 | ||
Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades | Q41884080 | ||
Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases | Q42462628 | ||
Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin. | Q42502352 | ||
Receptor-mediated activation of heterotrimeric G-proteins in living cells | Q43551201 | ||
Thyroid-stimulating hormone binding to beef thyroid membranes. Relation to adenylate cyclase activity | Q43829708 | ||
Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes | Q43901717 | ||
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells | Q44479240 | ||
Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1. | Q44831766 | ||
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons | Q45964672 | ||
Differential involvement of the actin cytoskeleton in differentiation and mitogenesis of thyroid cells: inactivation of Rho proteins contributes to cyclic adenosine monophosphate-dependent gene expression but prevents mitogenesis | Q46669908 | ||
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway | Q46853318 | ||
Photoaffinity labeling of A1-adenosine receptors | Q48435263 | ||
Nycthemeral patterns of thyroid hormones and their relationships with thyrotropin variations and sleep structure | Q48849564 | ||
Transgenic fruit-flies expressing a FRET-based sensor for in vivo imaging of cAMP dynamics. | Q50670235 | ||
Highly inclined thin illumination enables clear single-molecule imaging in cells. | Q53442959 | ||
Internalization and recycling pathways of the thyrotropin receptor. | Q55033324 | ||
Signaling on the endocytic pathway | Q57359903 | ||
Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling | Q57371068 | ||
Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling | Q57374826 | ||
Giving Space to Cell Signaling | Q57711626 | ||
Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate | Q63387803 | ||
Derivation of mouse embryonic stem cells | Q63407375 | ||
Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization | Q72173227 | ||
Long-term synaptic facilitation in the absence of short-term facilitation in Aplysia neurons | Q72535972 | ||
Thyrocyte integration, and thyroid folliculogenesis and tissue regeneration: perspective for thyroid tissue engineering | Q34291761 | ||
Role of endocytosis in signalling and regulation of G-protein-coupled receptors | Q34332431 | ||
The Virtual Cell: a software environment for computational cell biology | Q34392313 | ||
'Green mice' as a source of ubiquitous green cells. | Q34428099 | ||
Cell-signalling dynamics in time and space | Q34495098 | ||
Computational cell biology: spatiotemporal simulation of cellular events | Q34623629 | ||
Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator | Q34650064 | ||
Signal transduction and endocytosis: close encounters of many kinds | Q34770359 | ||
Quantitative cell biology with the Virtual Cell | Q35565895 | ||
Intracellular chloride channels: determinants of function in the endosomal pathway. | Q35776789 | ||
Not just a sink: endosomes in control of signal transduction | Q35840127 | ||
The ocular albinism type 1 (OA1) protein and the evidence for an intracellular signal transduction system involved in melanosome biogenesis | Q36200459 | ||
Phagocytosis induced by thyrotropin in cultured thyroid cells is associated with myosin light chain dephosphorylation and stress fiber disruption | Q36232652 | ||
Compartmentalization of adenylate cyclase and cAMP signalling | Q36295428 | ||
Accessory proteins for G proteins: partners in signaling. | Q36364667 | ||
Phosphodiesterases and compartmentalized cAMP signalling in the heart | Q36391237 | ||
Endocytosis conducts the cell signaling orchestra | Q36418350 | ||
Monitoring of cAMP synthesis and degradation in living cells | Q36432214 | ||
Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion | Q36436363 | ||
Relaxing the actin cytoskeleton for adhesion and movement with Ena/VASP. | Q36527160 | ||
Functional localization of cAMP signalling in cardiac myocytes. | Q36542000 | ||
Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling | Q36542008 | ||
Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. | Q36729142 | ||
Monitoring receptor signaling by intramolecular FRET. | Q36962644 | ||
One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A. | Q37011189 | ||
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. | Q37080605 | ||
Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments | Q37692357 | ||
Calcium ions, active zones and synaptic transmitter release | Q38201298 | ||
Reduction of adenylate cyclase activity in lysates of human platelets by the alpha-adrenergic component of epinephrine | Q39137213 | ||
Cyclic AMP diffusion coefficient in frog olfactory cilia | Q40143556 | ||
Selective modulation of protein kinase A I and II reveals distinct roles in thyroid cell gene expression and growth. | Q40247954 | ||
Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes | Q40370148 | ||
Beta-adrenergic- and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes detected with FRET-based biosensor. | Q40443081 | ||
Role of heterotrimeric GTP binding proteins in vesicular protein transport: indications for both classical and alternative G protein cycles | Q40463775 | ||
Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium. | Q40478581 | ||
Novel single chain cAMP sensors for receptor-induced signal propagation. | Q40539533 | ||
Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Ialpha and green fluorescent proteins | Q40834397 | ||
The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase IIbeta | Q41159170 | ||
Actin stress fiber disruption and tropomyosin isoform switching in normal thyroid epithelial cells stimulated by thyrotropin and phorbol esters | Q41269449 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | G protein-coupled receptor | Q38173 |
P304 | page(s) | e1000172 | |
P577 | publication date | 2009-08-01 | |
P1433 | published in | PLOS Biology | Q1771695 |
P1476 | title | Persistent cAMP-signals triggered by internalized G-protein-coupled receptors | |
P478 | volume | 7 |
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Q35817527 | A negative allosteric modulator demonstrates biased antagonism of the follicle stimulating hormone receptor |
Q42290882 | A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling |
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Q46039285 | Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4. |
Q30827621 | Axial tubule junctions control rapid calcium signaling in atria |
Q61979192 | Beyond Intracellular Signaling: The Ins and Outs of Second Messengers Microdomains |
Q64097803 | Biased Signaling and Allosteric Modulation at the FSHR |
Q99574272 | Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases |
Q47231111 | Biased signalling: from simple switches to allosteric microprocessors |
Q37609042 | Bicarbonate-sensing soluble adenylyl cyclase is present in the cell cytoplasm and nucleus of multiple shark tissues |
Q38098831 | Biophysical techniques for detection of cAMP and cGMP in living cells |
Q38760680 | Ca(2+)/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function |
Q26801424 | Can residence time offer a useful strategy to target agonist drugs for sustained GPCR responses? |
Q52806005 | Canonical TSH Regulation of Cathepsin-Mediated Thyroglobulin Processing in the Thyroid Gland of Male Mice Requires Taar1 Expression. |
Q47718667 | Caveolins as regulators of stress adaptation |
Q37755651 | Cellular signalling: Peptide hormones and growth factors |
Q33927508 | Chaperoning G protein-coupled receptors: from cell biology to therapeutics |
Q55623780 | Cigarette smoke up-regulates PDE3 and PDE4 to decrease cAMP in airway cells. |
Q38079253 | Compartmentation of cAMP signalling in cardiomyocytes in health and disease |
Q52659149 | Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. |
Q30557505 | Conformational biosensors reveal GPCR signalling from endosomes. |
Q37994652 | Congenital nephrogenic diabetes insipidus: the current state of affairs |
Q36503929 | Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome |
Q41886620 | Database(d) Guidelines: A Small World |
Q38183356 | Decoding spatial and temporal features of neuronal cAMP/PKA signaling with FRET biosensors |
Q34997765 | Decreased degradation of internalized follicle-stimulating hormone caused by mutation of aspartic acid 6.30(550) in a protein kinase-CK2 consensus sequence in the third intracellular loop of human follicle-stimulating hormone receptor |
Q48188760 | Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor |
Q38205100 | Developments in preclinical cancer imaging: innovating the discovery of therapeutics. |
Q37622408 | Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias. |
Q46024340 | Dissecting signaling and functions of adhesion G protein-coupled receptors. |
Q37285415 | Distinct G protein-coupled receptor recycling pathways allow spatial control of downstream G protein signaling. |
Q39762345 | Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells. |
Q36887413 | Divergent modes for cargo-mediated control of clathrin-coated pit dynamics |
Q37417683 | Dynamic kisspeptin receptor trafficking modulates kisspeptin-mediated calcium signaling |
Q38820602 | Effects of sodium ions on rat thyrocyte (FRTL-5 cells) swelling- and thyrotropin-activated taurine efflux dependent on cAMP and Epac |
Q53819708 | Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. |
Q39436094 | Endocrinology and the brain: corticotropin-releasing hormone signaling |
Q37405423 | Endocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses |
Q37980726 | Endocytosis and signaling: cell logistics shape the eukaryotic cell plan |
Q29616848 | Endocytosis and signalling: intertwining molecular networks |
Q48404644 | Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons |
Q28116057 | Endocytosis promotes rapid dopaminergic signaling |
Q37790423 | Endosomal Signaling and a Novel Pathway Defined by the Natural Killer Receptor KIR2DL4 (CD158d) |
Q35563982 | Endosomal generation of cAMP in GPCR signaling |
Q47583720 | Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission |
Q36091297 | Eosinophil crystalloid granules: structure, function, and beyond |
Q35515532 | Extra-long Gαs variant XLαs protein escapes activation-induced subcellular redistribution and is able to provide sustained signaling |
Q28307493 | FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells |
Q35005671 | Formoterol and salmeterol induce a similar degree of β2-adrenoceptor tolerance in human small airways but via different mechanisms |
Q37977175 | From parathyroid hormone to cytosolic Ca2+ signals. |
Q41902981 | Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking |
Q46765399 | Functional selectivity of GPCR-directed drug action through location bias |
Q38962494 | G Protein-Coupled Receptor Endosomal Signaling and Regulation of Neuronal Excitability and Stress Responses: Signaling Options and Lessons From the PAC1 Receptor |
Q35172569 | G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes |
Q37970012 | G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function. |
Q96220934 | G protein-regulated endocytic trafficking of adenylyl cyclase type 9 |
Q43789204 | G-Protein Dependent Signal Transduction and Ubiquitination in Dictyostelium |
Q64245124 | G-Protein-Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases |
Q39020873 | GPCR Signaling and Trafficking: The Long and Short of It. |
Q37141950 | GPCR signaling along the endocytic pathway |
Q28277702 | GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling |
Q90494776 | Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks |
Q60432477 | Genetically Encoding Quinoline Reverses Chromophore Charge and Enables Fluorescent Protein Brightening in Acidic Vesicles |
Q34975601 | Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells |
Q38184156 | Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation |
Q26781567 | Genetically-encoded tools for cAMP probing and modulation in living systems |
Q39165040 | Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells. |
Q83229721 | Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy |
Q42377918 | Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment |
Q36839542 | Gαs regulates the post-endocytic sorting of G protein-coupled receptors |
Q92703368 | Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium |
Q35558398 | Heterotrimeric G protein-mediated signaling and its non-canonical regulation in the heart |
Q35738830 | Histamine receptors of cones and horizontal cells in Old World monkey retinas |
Q90423778 | Homologous Regulation of Mu Opioid Receptor Recycling by G βγ , Protein Kinase C, and Receptor Phosphorylation |
Q49787366 | Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes |
Q39283124 | Impact of Gravity on Thyroid Cells. |
Q89061051 | Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System |
Q39354809 | Impairment of adenylyl cyclase 2 function and expression in hypoxanthine phosphoribosyltransferase-deficient rat B103 neuroblastoma cells as model for Lesch-Nyhan disease: BODIPY-forskolin as pharmacological tool |
Q55365511 | In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function. |
Q48749621 | In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease |
Q35769802 | In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs |
Q35618348 | Inhibition of follicle-stimulating hormone-induced preovulatory follicles in rats treated with a nonsteroidal negative allosteric modulator of follicle-stimulating hormone receptor |
Q36989788 | Inside job: ligand-receptor pharmacology beneath the plasma membrane |
Q37486049 | Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET. |
Q35566889 | Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles |
Q41620984 | Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription |
Q57144951 | International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature |
Q35383816 | International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors. |
Q52656382 | Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. |
Q27691286 | Intracellular cAMP signaling by soluble adenylyl cyclase. |
Q47668309 | Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches |
Q33623314 | Investigating signaling consequences of GPCR trafficking in the endocytic pathway |
Q35582503 | Involvement of F-actin in chaperonin-containing t-complex 1 beta regulating mouse mesangial cell functions in a glucose-induction cell model |
Q34915658 | Kinin-stimulated B1 receptor signaling depends on receptor endocytosis whereas B2 receptor signaling does not. |
Q42016775 | Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII. |
Q39371960 | Live-cell imaging of cell signaling using genetically encoded fluorescent reporters |
Q34573953 | Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5. |
Q38803217 | Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor. |
Q38644201 | Loss of sorting nexin 5 stabilizes internalized growth factor receptors to promote thyroid cancer progression. |
Q90595855 | Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis |
Q59809129 | Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays |
Q39637973 | Methods to detect cell surface expression and constitutive activity of GPR6 |
Q38459674 | Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling |
Q33631599 | Minireview: Spatial Programming of G Protein-Coupled Receptor Activity: Decoding Signaling in Health and Disease |
Q28080425 | Model Organisms in G Protein-Coupled Receptor Research |
Q37902142 | Modeling of spatially-restricted intracellular signaling |
Q36392981 | Modulating neuromodulation by receptor membrane traffic in the endocytic pathway |
Q37062556 | Molecular Pharmacology of δ-Opioid Receptors |
Q36599592 | Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. |
Q38166604 | Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung |
Q89897792 | Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84 |
Q39154920 | Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief |
Q36377424 | Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity |
Q36190508 | Non-canonical signaling of the PTH receptor |
Q27006799 | Non-traditional roles of G protein-coupled receptors in basic cell biology |
Q36567861 | Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex |
Q37201202 | Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. |
Q39433833 | Opportunities for therapeutic antibodies directed at G-protein-coupled receptors |
Q57793603 | Optical tools for understanding the complexity of β-cell signalling and insulin release |
Q57095722 | PACAP-Induced PAC1 Receptor Internalization and Recruitment of Endosomal Signaling Regulate Cardiac Neuron Excitability |
Q33701487 | PACAP-induced ERK activation in HEK cells expressing PAC1 receptors involves both receptor internalization and PKC signaling |
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Q34378836 | Persistent cAMP signaling by thyrotropin (TSH) receptors is not dependent on internalization |
Q64993079 | Persistent effects of cyclic adenosine monophosphate are directly responsible for maintaining a neural network state. |
Q36117496 | Persistent signaling by thyrotropin-releasing hormone receptors correlates with G-protein and receptor levels |
Q37331817 | Pharmacological distinction between soluble and transmembrane adenylyl cyclases |
Q88882229 | Pharmacological modulation of the CO2/HCO3-/pH-, calcium-, and ATP-sensing soluble adenylyl cyclase |
Q35027128 | Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. |
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Q38521179 | Postendocytic Sorting of Adrenergic and Opioid Receptors: New Mechanisms and Functions. |
Q57292518 | Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations |
Q37220612 | Proliferation in cardiac fibroblasts induced by β1-adrenoceptor autoantibody and the underlying mechanisms |
Q42723814 | Quaternary structures of opsin in live cells revealed by FRET spectrometry |
Q28069545 | Recent advances in understanding the extracellular calcium-sensing receptor |
Q74441885 | Receptor signals come in waves |
Q46174607 | Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability. |
Q34795621 | Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells |
Q34819768 | Retromer terminates the generation of cAMP by internalized PTH receptors |
Q48594442 | Role for endocytosis of a constitutively active GPCR (GPR185) in releasing vertebrate oocyte meiotic arrest |
Q35964984 | Role of soluble adenylyl cyclase in the heart |
Q34869610 | Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase. |
Q26766002 | Signal processing by the endosomal system |
Q34485942 | Signaling endosomes: seeing is believing |
Q42665090 | Signaling: retromer arrests receptor on the run. |
Q35140849 | Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence |
Q51687154 | Soluble adenylyl cyclase is an acid-base sensor in epithelial base-secreting cells. |
Q33865318 | Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors. |
Q30415400 | Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice |
Q26866056 | Spatial control of cAMP signalling in health and disease |
Q34514108 | Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis |
Q90011044 | Spatial regulation of GPR64/ADGRG2 signaling by β-arrestins and GPCR kinases |
Q42248987 | Spatial resolution of cAMP signaling by soluble adenylyl cyclase |
Q37583445 | Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments. |
Q38617393 | Spatio-Temporal Parameters of Endosomal Signaling in Cancer: Implications for New Treatment Options |
Q39152899 | Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells |
Q46069927 | Src family kinase inhibitors blunt the PACAP-induced PAC1 receptor endocytosis, phosphorylation of ERK and increase in cardiac neuron excitability |
Q28385866 | Striatal neurones have a specific ability to respond to phasic dopamine release |
Q64254283 | Structural Insights into CB1 Receptor Biased Signaling |
Q27658553 | Structural Requirements for PACSIN/Syndapin Operation during Zebrafish Embryonic Notochord Development |
Q30401802 | Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work |
Q91330297 | Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex |
Q26800056 | Studying GPCR/cAMP pharmacology from the perspective of cellular structure |
Q89912914 | Studying signal compartmentation in adult cardiomyocytes |
Q87872722 | Subcellular Organization of GPCR Signaling |
Q26781574 | Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins |
Q35794921 | Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies |
Q36232983 | Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists |
Q82362862 | Temporally resolved cAMP monitoring in endothelial cells uncovers a thrombin-induced [cAMP] elevation mediated via the Ca²+-dependent production of prostacyclin |
Q35845783 | The Activation Mechanism of Glycoprotein Hormone Receptors with Implications in the Cause and Therapy of Endocrine Diseases |
Q52628050 | The Different Facets of Extracellular Calcium Sensors: Old and New Concepts in Calcium-Sensing Receptor Signalling and Pharmacology. |
Q39381430 | The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling |
Q28730256 | The impact of long-term exposure to space environment on adult mammalian organisms: a study on mouse thyroid and testis |
Q27028148 | The role of soluble adenylyl cyclase in neurite outgrowth |
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