Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin.

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Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1020268105
P356DOI10.1007/BF03348894
P698PubMed publication ID8227980

P50authorLuca PersaniQ42816787
Marian LudgateQ43227313
Rossella EliseiQ57026751
P2093author name stringG Vassart
L Chiovato
P Beck-Peccoz
P Vitti
M Tonacchera
G Faglia
C Mammoli
P2860cites workMolecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptorQ28255504
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Cloning, sequencing and expression of human TSH receptorQ28276030
Intrinsic bioactivity of thyrotropin in human serum is inversely correlated with thyroid hormone concentrations. Application of a new bioassay using the FRTL-5 rat thyroid cell strainQ34571402
Thyroid-stimulating hormone: biosynthesis, cell biology, and bioactivityQ37938860
The glycoprotein hormones: recent studies of structure-function relationshipsQ38190422
Thyrotropin Secretion in Patients with Central Hypothyroidism: Evidence for Reduced Biological Activity of Immunoreactive Thyrotropin*Q39665821
Glycosylation and posttranslational processing of thyroid-stimulating hormone: clinical implications.Q39849288
Recombinant human thyroid-stimulating hormone: initial bioactivity assessment using human fetal thyroid cellsQ41150853
Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor.Q41577169
Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor proteinQ41592082
Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodiesQ41720558
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clonesQ41721055
The role of carbohydrate in thyrotropin action assessed by a novel approach using enzymatic deglycosylationQ41728067
Decreased receptor binding of biologically inactive thyrotropin in central hypothyroidism. Effect of treatment with thyrotropin-releasing hormoneQ43431522
Thyroid-stimulating antibody mimics thyrotropin in its ability to desensitize the adenosine 3',5'-monophosphate response to acute stimulation in continuously cultured rat thyroid cells (FRT-L5).Q43856384
The secretion of thyrotrophin with impaired biological activity in patients with hypothalamic-pituitary diseaseQ44953846
Studies on thyroid stimulating hormone and the long-acting thyroid stimulating hormoneQ46619396
Differences in the metabolic clearance of pituitary and serum thyrotropin (TSH) derived from euthyroid and hypothyroid rats: effects of chemical deglycosylation of pituitary TSH.Q48269751
Regulation of thyrotropin (TSH) bioactivity by TSH-releasing hormone and thyroid hormoneQ48350097
Thyrotropin-Secreting Pituitary Adenomas: Clinical and Biochemical HeterogeneityQ58004806
Multiple expressions of the activity of guanine nucleotide regulatory protein in human thyroid adenylate cyclaseQ67241625
Human chorionic gonadotropin (hCG) interacts directly with recombinant human TSH receptorsQ67488807
Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: evidence for secretion of TSH with increased bioactivityQ68955358
A sensitive and practical bioassay for thyrotropin using cultured FRTL-5 cells: assessment of bioactivity for serum TSH in patients with chronic renal failureQ69713756
Concanavalin-A, lentil, and ricin lectin affinity binding characteristics of human thyrotropin: differences in the sialylation of thyrotropin in sera of euthyroid, primary, and central hypothyroid patientsQ69752357
A sensitive thyrotropin (TSH) bioassay based on iodide uptake in rat FRTL-5 thyroid cells: comparison with the adenosine 3',5'-monophosphate response to human serum TSH and enzymatically deglycosylated bovine and human TSHQ69807072
Alterations in the sialylation and sulfation of secreted mouse thyrotropin in primary hypothyroidismQ69973773
Changes in the multiple components of rat pituitary TSH and TSH beta subunit following thyroidectomyQ71266417
Purification of thyrotropin and other glycoprotein hormones by immunoaffinity chromatographyQ71496943
Graves’ IgG stimulation of continuously cultured rat thyroid cells: a sensitive and potentially useful clinical assayQ72940702
The bioassay of thyrotropin in serumQ78324095
P433issue7
P304page(s)511-519
P577publication date1993-07-01
P1433published inJournal of Endocrinological InvestigationQ15766847
P1476titleMeasurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin
P478volume16

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cites work (P2860)
Q581246222018 European Thyroid Association (ETA) Guidelines on the Diagnosis and Management of Central Hypothyroidism
Q73196603Bioactivity and glycosylation of circulating prolactin in various physiological and pathological conditions
Q41433781Detection of antibodies blocking thyrotropin effect using Chinese hamster ovary cells transfected with the cloned human TSH receptor.
Q35126471Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
Q37662277Multiple Hürthle cell adenomas in a patient with thyroid hormone resistance
Q27329609Persistent cAMP-signals triggered by internalized G-protein-coupled receptors
Q43042591Rituximab treatment in patients with active Graves' orbitopathy: effects on proinflammatory and humoral immune reactions.
Q61816694The diagnosis and management of central hypothyroidism in 2018
Q34220128The expression of the thyroid-stimulating hormone (TSH) receptor and the cAMP-dependent protein kinase RII beta regulatory subunit confers TSH-cAMP-dependent growth to mouse fibroblasts
Q77999142Thyroid hemiagenesis and elevated thyrotropin levels in a child with Williams syndrome
Q34373806Thyrotropin isoforms: implications for thyrotropin analysis and clinical practice
Q71488626Thyrotropin with decreased biological activity, a delayed consequence of cranial irradiation for nasopharyngeal carcinoma
Q41207603Transfection with the cDNA of the human thyrotropin receptor of a poorly differentiated rat thyroid cell line (FRT).

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