scholarly article | Q13442814 |
P2093 | author name string | Srgjan Civciristov | |
Oded Kleifeld | |||
Meritxell Canals | |||
William S Hlavacek | |||
Bronwyn A Evans | |||
Steven J Charlton | |||
Michelle L Halls | |||
Ryan Suderman | |||
Andrew M Ellisdon | |||
Cindy K Pon | |||
Michelle L. Halls | |||
Bronwyn A. Evans | |||
Andrew M. Ellisdon | |||
Cindy K. Pon | |||
Steven J. Charlton | |||
William S. Hlavacek | |||
P2860 | cites work | Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function | Q69920678 |
Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation | Q73561196 | ||
Naloxone in ultralow concentration restores endomorphin-1-evoked Ca²⁺ signaling in lipopolysaccharide pretreated astrocytes | Q83243765 | ||
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex | Q24293265 | ||
Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR | Q24336882 | ||
AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex | Q24568274 | ||
Protein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptor | Q24594201 | ||
Long‐lasting target binding and rebinding as mechanisms to prolong in vivo drug action | Q24595639 | ||
Crystal structure of the β2 adrenergic receptor-Gs protein complex | Q24635327 | ||
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor | Q24653887 | ||
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C | Q24675024 | ||
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand | Q24676976 | ||
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
Persistent cAMP-signals triggered by internalized G-protein-coupled receptors | Q27329609 | ||
Structure and dynamics of the M3 muscarinic acetylcholine receptor | Q27677433 | ||
Structure and signaling mechanism of a zinc-sensory diguanylate cyclase | Q27684826 | ||
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
Efficient selection for high-expression transfectants with a novel eukaryotic vector | Q27860810 | ||
Fiji: an open-source platform for biological-image analysis | Q27860912 | ||
Endocytosis promotes rapid dopaminergic signaling | Q28116057 | ||
AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation | Q28118719 | ||
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists | Q28131785 | ||
Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling | Q28141060 | ||
The scaffold protein gravin (cAMP-dependent protein kinase-anchoring protein 250) binds the beta 2-adrenergic receptor via the receptor cytoplasmic Arg-329 to Leu-413 domain and provides a mobile scaffold during desensitization | Q28213312 | ||
The interleukin-1 family: 10 years of discovery | Q28243296 | ||
Visualization of arrestin recruitment by a G-protein-coupled receptor | Q28244290 | ||
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling | Q28277702 | ||
Dynamic complexes of beta2-adrenergic receptors with protein kinases and phosphatases and the role of gravin | Q28293178 | ||
beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi | Q28576849 | ||
AKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systems | Q28577266 | ||
2016 update of the PRIDE database and its related tools | Q28603110 | ||
Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion | Q28817609 | ||
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification | Q29547200 | ||
Small GTP-binding proteins | Q29547372 | ||
UniProt: a hub for protein information | Q29547457 | ||
Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis | Q29615199 | ||
Proteomics. Tissue-based map of the human proteome | Q29617248 | ||
Pathway and mechanism of drug binding to G-protein-coupled receptors. | Q30503489 | ||
Conformational biosensors reveal GPCR signalling from endosomes. | Q30557505 | ||
Counting low-copy number proteins in a single cell | Q33268264 | ||
M3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency. | Q33676287 | ||
Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment | Q33782677 | ||
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis | Q33788491 | ||
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells | Q34324446 | ||
Regulation by Ca2+-signaling pathways of adenylyl cyclases | Q34413032 | ||
Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis | Q34514108 | ||
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. | Q34544553 | ||
Retromer terminates the generation of cAMP by internalized PTH receptors | Q34819768 | ||
AKAP5 and AKAP12 Form Homo-oligomers | Q35040162 | ||
Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1) | Q35044409 | ||
Scaffold-mediated nucleation of protein signaling complexes: elementary principles. | Q35109787 | ||
Identification of a chemoreceptor zinc-binding domain common to cytoplasmic bacterial chemoreceptors. | Q35192033 | ||
AKAP12 and AKAP5 form higher-order hetero-oligomers | Q35206428 | ||
Structural aspects of M₃ muscarinic acetylcholine receptor dimer formation and activation | Q35790289 | ||
β(2)-Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail | Q36024912 | ||
Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2. | Q36118120 | ||
Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source | Q36302676 | ||
Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex | Q36567861 | ||
Stochastic simulation of chemical kinetics | Q36622158 | ||
Characterization of a panel of six beta2-adrenergic receptor antibodies by indirect immunofluorescence microscopy | Q36657332 | ||
Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach | Q36974435 | ||
cAMP-specific phosphodiesterase-4D5 (PDE4D5) provides a paradigm for understanding the unique non-redundant roles that PDE4 isoforms play in shaping compartmentalized cAMP cell signalling. | Q36979472 | ||
A genetically encoded fluorescent sensor of ERK activity | Q37039507 | ||
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation | Q37127495 | ||
Distinct enzyme combinations in AKAP signalling complexes permit functional diversity | Q37582031 | ||
Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold? | Q37800215 | ||
Allostery in GPCRs: 'MWC' revisited. | Q37932797 | ||
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. | Q38302685 | ||
Binding Kinetics and Pathways of Ligands to GPCRs | Q38711441 | ||
Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals. | Q39048230 | ||
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief | Q39154920 | ||
Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL). | Q39527452 | ||
Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics | Q39701404 | ||
Interaction with AKAP79 modifies the cellular pharmacology of PKC. | Q39734401 | ||
Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells. | Q39762345 | ||
Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and beta2-adrenoceptor mechanisms | Q39972489 | ||
Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling | Q40009966 | ||
Live cell analysis of G protein beta5 complex formation, function, and targeting | Q40114509 | ||
Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling | Q40244883 | ||
Unusual Venoconstrictor Effects of Angiotensin | Q40328518 | ||
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells. | Q40395764 | ||
Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8). | Q40471541 | ||
Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors | Q40889383 | ||
Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. | Q41040815 | ||
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region | Q42478536 | ||
Beta2-adrenoceptors and non-beta-adrenoceptors mediate effects of BRL37344 and clenbuterol on glucose uptake in soleus muscle: studies using knockout mice | Q42943914 | ||
Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage | Q43706917 | ||
Site-directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function | Q43873000 | ||
Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes | Q43901717 | ||
The Influence of receptor kinetics on the onset and duration of action and the therapeutic index of NVA237 and tiotropium | Q47314068 | ||
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission | Q47583720 | ||
Micro-pharmacokinetics: Quantifying local drug concentration at live cell membranes | Q50330984 | ||
Imaging protein activity in live embryos using fluorescence resonance energy transfer biosensors. | Q51504985 | ||
Muscarinic receptor family interacting proteins: role in receptor function. | Q51627580 | ||
Observed drug-receptor association rates are governed by membrane affinity: the importance of establishing "micro-pharmacokinetic/pharmacodynamic relationships" at the β2-adrenoceptor. | Q51750333 | ||
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. | Q51758332 | ||
Detection and Quantification of Intracellular Signaling Using FRET-Based Biosensors and High Content Imaging. | Q53384325 | ||
Insights into signaling from the β2-adrenergic receptor structure | Q56648606 | ||
Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling | Q57374826 | ||
Endothelium-Dependent Response of the Rabbit Aorta to Femtomolar Concentrations of Angiotensin II | Q67696423 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 551 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | eaan1188 | |
P577 | publication date | 2018-10-09 | |
P1433 | published in | Science Signaling | Q7433604 |
P1476 | title | Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations | |
P478 | volume | 11 |
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