scholarly article | Q13442814 |
P50 | author | Thomas J Gardella | Q91142686 |
P2093 | author name string | Jean-Pierre Vilardaga | |
Timothy N Feinstein | |||
Vanessa L Wehbi | |||
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Endocytosis promotes rapid dopaminergic signaling | Q28116057 | ||
Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms | Q28181949 | ||
Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors | Q28262889 | ||
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Retrograde transport from endosomes to the trans-Golgi network | Q29617826 | ||
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis | Q29619487 | ||
A form of Jansen's metaphyseal chondrodysplasia with limited metabolic and skeletal abnormalities is caused by a novel activating parathyroid hormone (PTH)/PTH-related peptide receptor mutation | Q30941843 | ||
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GPCR and G proteins: drug efficacy and activation in live cells. | Q33642442 | ||
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. | Q34115829 | ||
Molecular properties of the PTH/PTHrP receptor | Q34276973 | ||
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. | Q34544553 | ||
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor | Q34708055 | ||
Retromer terminates the generation of cAMP by internalized PTH receptors | Q34819768 | ||
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling | Q35201347 | ||
Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations | Q35622858 | ||
Parathyroid hormone and parathyroid hormone-related peptide, and their receptors | Q36032066 | ||
Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor. | Q36372640 | ||
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation | Q36411260 | ||
Trafficking of G protein-coupled receptors | Q36594595 | ||
Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. | Q36599592 | ||
Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors | Q36773326 | ||
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation | Q36946514 | ||
Regulation of GPCRs by endocytic membrane trafficking and its potential implications | Q37053838 | ||
Elevations in serum and urinary calcium with parathyroid hormone (1-84) with and without alendronate for osteoporosis | Q37101657 | ||
The arrestin fold: variations on a theme | Q37236186 | ||
beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation | Q37350606 | ||
Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking | Q37484589 | ||
Endocytosis and signaling | Q37862859 | ||
Receptor tyrosine kinase-G-protein-coupled receptor signalling platforms: out of the shadow? | Q37879733 | ||
Analysis of parathyroid hormone's principal receptor-binding region by site-directed mutagenesis and analog design | Q38319688 | ||
beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics | Q40043280 | ||
Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins | Q40175757 | ||
Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells | Q40208196 | ||
A hypocalcemic child with a novel activating mutation of the calcium-sensing receptor gene: successful treatment with recombinant human parathyroid hormone | Q40293755 | ||
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. | Q40313388 | ||
A docking site for G protein βγ subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways | Q40385537 | ||
G alpha12/G alpha13 subunits of heterotrimeric G proteins mediate parathyroid hormone activation of phospholipase D in UMR-106 osteoblastic cells. | Q40459760 | ||
Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor | Q40490382 | ||
Conformational states of the corticotropin releasing factor 1 (CRF1) receptor: detection, and pharmacological evaluation by peptide ligands | Q40558905 | ||
A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways | Q40740952 | ||
Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association | Q40765935 | ||
Analysis of parathyroid hormone (PTH)/secretin receptor chimeras differentiates the role of functional domains in the pth/ pth-related peptide (PTHrP) receptor on hormone binding and receptor activation | Q40795070 | ||
Endocytosis of ligand-human parathyroid hormone receptor 1 complexes is protein kinase C-dependent and involves beta-arrestin2. Real-time monitoring by fluorescence microscopy | Q40924347 | ||
Coupling of the PTH/PTHrP receptor to multiple G-proteins. Direct demonstration of receptor activation of Gs, Gq/11, and Gi(1) by [alpha-32P]GTP-gamma-azidoanilide photoaffinity labeling | Q41016491 | ||
Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems | Q41089415 | ||
Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization | Q41238228 | ||
Parathyroid hormone (PTH)-PTH-related peptide hybrid peptides reveal functional interactions between the 1-14 and 15-34 domains of the ligand | Q41358649 | ||
The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34). | Q41489259 | ||
Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation | Q43511313 | ||
Enhanced activity in parathyroid hormone-(1-14) and -(1-11): novel peptides for probing ligand-receptor interactions | Q43646678 | ||
Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and beta-arrestins. | Q44142742 | ||
Occurrence of hypercalciuria in patients with osteoporosis treated with teriparatide | Q44284969 | ||
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells | Q44479240 | ||
Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium. | Q44582481 | ||
NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling | Q46989494 | ||
Teriparatide in postmenopausal women with osteoporosis and mild or moderate renal impairment. | Q51932388 | ||
Measurement of agonist and antagonist ligand-binding parameters at the human parathyroid hormone type 1 receptor: evaluation of receptor states and modulation by guanine nucleotide. | Q51984622 | ||
Recessive mutations in PTHR1 cause contrasting skeletal dysplasias in Eiken and Blomstrand syndromes. | Q52085977 | ||
Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor | Q73703963 | ||
G protein signaling in yeast: new components, new connections, new compartments | Q79397313 | ||
Parathyroid hormone-related protein: an essential physiological regulator of adult bone mass | Q80362942 | ||
P433 | issue | 8 | |
P304 | page(s) | 423-431 | |
P577 | publication date | 2012-06-16 | |
P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
P1476 | title | Non-canonical signaling of the PTH receptor | |
P478 | volume | 33 |
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Q34540545 | A Pluridimensional View of Biased Agonism |
Q34218573 | A high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization. |
Q27313518 | Activation of microtubule dynamics increases neuronal growth via the nerve growth factor (NGF)- and Gαs-mediated signaling pathways |
Q36431762 | Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling |
Q34067074 | Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase |
Q35563982 | Endosomal generation of cAMP in GPCR signaling |
Q39193257 | G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms |
Q35172569 | G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes |
Q34286441 | Green fluorescent protein fused to peptide agonists of two dissimilar G protein-coupled receptors: novel ligands of the bradykinin B2 (rhodopsin family) receptor and parathyroid hormone PTH1 (secretin family) receptor |
Q35383816 | International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors. |
Q38260285 | Investigational parathyroid hormone receptor analogs for the treatment of osteoporosis |
Q51499124 | Measurement of Receptor Signaling Bias. |
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Q36392981 | Modulating neuromodulation by receptor membrane traffic in the endocytic pathway |
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Q37201202 | Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. |
Q90539552 | Opioid pharmacology under the microscope |
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Q38824663 | Parathyroid Hormone-Related Protein, Its Regulation of Cartilage and Bone Development, and Role in Treating Bone Diseases |
Q37149901 | Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response |
Q36798625 | Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth |
Q90352755 | The browning of white adipose tissue and body weight loss in primary hyperparathyroidism |
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