Retrograde transport from endosomes to the trans-Golgi network

scientific article (publication date: August 2006)

Retrograde transport from endosomes to the trans-Golgi network is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1028847637
P356DOI10.1038/NRM1985
P3181OpenCitations bibliographic resource ID1017924
P698PubMed publication ID16936697
P5875ResearchGate publication ID6851320

P50authorJuan S. BonifacinoQ50726280
P2093author name stringRaul Rojas
P2860cites workTGN38/41: a molecule on the moveQ75293395
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexesQ24290579
The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphateQ24291846
Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi networkQ24297647
The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptorQ24299142
Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositidesQ24308072
TIP47: a cargo selection device for mannose 6-phosphate receptor traffickingQ24316494
Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane traffickingQ24318887
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomesQ24323356
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromerQ24336448
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptorQ24336478
Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi networkQ24534275
PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.Q24534392
A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membraneQ24536667
Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-golgi networkQ24564506
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeastQ24670484
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoformQ24671033
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cellsQ24671475
Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cellsQ24673272
The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domainQ24673655
Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35pQ24677799
Rab11 regulates recycling through the pericentriolar recycling endosomeQ24681897
Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transportQ24682101
The ESCRT complexes: structure and mechanism of a membrane-trafficking networkQ24683234
BAR domains as sensors of membrane curvature: the amphiphysin BAR structureQ27642663
An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranesQ27930206
Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomesQ27931535
Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late GolgiQ27932636
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinaseQ27932803
Mutants in trs120 disrupt traffic from the early endosome to the late GolgiQ27932894
The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.Q27933615
The yeast clathrin adaptor protein complex 1 is required for the efficient retention of a subset of late Golgi membrane proteinsQ27936300
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6pQ27936691
Structural and functional analysis of a novel coiled-coil protein involved in Ypt6 GTPase-regulated protein transport in yeastQ27936918
Two syntaxin homologues in the TGN/endosomal system of yeastQ27937369
Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1pQ27937413
Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomesQ27937968
Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p.Q27938823
Yeast exocytic v-SNAREs confer endocytosisQ27939293
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 geneQ27939402
Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1pQ27940130
Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartmentsQ28114324
A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cellsQ28146062
Role of Rab9 GTPase in facilitating receptor recruitment by TIP47Q28189682
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteinsQ36321953
Glucose transporter 4: cycling, compartments and controversiesQ36327829
Role of tethering factors in secretory membrane traffic.Q36336697
Retrograde transport on the COG railway.Q36365803
The yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeletonQ36955558
A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptorQ37386983
In vitro formation of recycling vesicles from endosomes requires adaptor protein-1/clathrin and is regulated by rab4 and the connector rabaptin-5.Q37595151
Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPasesQ38299035
Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesisQ38355451
Endosome to Golgi transport of ricin is regulated by cholesterolQ38490873
Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrinQ40558989
Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sortingQ41233270
Characterization of the in vitro retrograde transport of MPR46.Q44655734
A novel assay reveals a role for soluble N-ethylmaleimide-sensitive fusion attachment protein in mannose 6-phosphate receptor transport from endosomes to the trans Golgi network.Q45936193
Structure of a lipid droplet protein; the PAT family member TIP47.Q47227013
SNAREs and trafficQ56850814
The galactose-specific recognition system of mammalian liver: the route of ligand internalization in rat hepatocytesQ71293185
Mannose 6-phosphate receptors: new twists in the taleQ28213265
tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centreQ28248461
Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assemblyQ28257489
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localizationQ28278951
Recycle your receptors with retromerQ28306101
Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cellsQ28506867
Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cellsQ28609354
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi networkQ28609803
Rab9 functions in transport between late endosomes and the trans Golgi networkQ28609814
Endocytic recyclingQ29547737
The mechanisms of vesicle budding and fusionQ29615234
mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsQ29622880
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesisQ29642793
The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane.Q30331083
Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.Q30336360
TIP47 associates with lipid dropletsQ31577024
Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiaeQ33893822
Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranesQ33944092
Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranesQ34311540
Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites.Q34405959
A novel mammalian retromer component, Vps26B.Q34454889
Mosaic organization of the endocytic pathwayQ34461685
Model-guided microarray implicates the retromer complex in Alzheimer's diseaseQ34471199
The trans Golgi network: sorting at the exit site of the Golgi complex.Q34562583
Three-dimensional structure of endosomes in BHK-21 cellsQ35602540
Sorting nexins--unifying trends and new perspectivesQ36000866
Delivery into cells: lessons learned from plant and bacterial toxinsQ36091291
Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiaeQ36137664
Protein sorting in the Golgi complex: shifting paradigmsQ36145969
Evolving endosomes: how many varieties and why?Q36173529
The Arf-like GTPase Arl1 and its role in membrane traffic.Q36206336
Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cellsQ36211900
Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transportQ36255884
Two separate signals act independently to localize a yeast late Golgi membrane protein through a combination of retrieval and retentionQ36259441
Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells.Q36321499
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectretrograde transport, endosome to GolgiQ21095309
P304page(s)568-579
P577publication date2006-08-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleRetrograde transport from endosomes to the trans-Golgi network
P478volume7

Reverse relations

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Q30533946Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control
Q35071524Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin.
Q24303674Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function
Q33754199Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria
Q51063354Real-time monitoring of vesicle pH in an endocytic pathway using an EGF-conjugated two-photon probe.
Q26830216Receptor tyrosine kinases in the nucleus
Q24321352Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination
Q28299673Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.
Q24648991Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes
Q41381112Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated
Q47727761Retriever fetches integrins from endosomes
Q37252890Retrograde Transport from Early Endosomes to the trans-Golgi Network Enables Membrane Wrapping and Egress of Vaccinia Virus Virions
Q37083291Retrograde traffic in the biosynthetic-secretory route
Q45318437Retrograde transport at the Trans-Golgi-Network
Q37861301Retrograde transport: two (or more) roads diverged in an endosomal tree?
Q24632869Retromer
Q45892377Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
Q39357458Retromer guides STxB and CD8-M6PR from early to recycling endosomes, EHD1 guides STxB from recycling endosome to Golgi
Q34819768Retromer terminates the generation of cAMP by internalized PTH receptors
Q38543983Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters.
Q34401990Retromer: a master conductor of endosome sorting
Q28303952Retromer: multipurpose sorting and specialization in polarized transport
Q38144759Ribosome-inactivating proteins: potent poisons and molecular tools
Q29616548Role of Rab GTPases in membrane traffic and cell physiology
Q26766012Role of the Retromer Complex in Neurodegenerative Diseases
Q34828379SMAP2 regulates retrograde transport from recycling endosomes to the Golgi.
Q24304125SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors
Q24304190SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors
Q24300067SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment
Q24310765SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery
Q50299818SYS1 binds AcM-ARFRP1
Q91612189Schaaf-Yang syndrome shows a Prader-Willi syndrome-like phenotype during infancy
Q36775809Screening for VPS35 mutations in Parkinson's disease
Q30495517Secretory granule membrane protein recycles through multivesicular bodies
Q27303797Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans
Q21263006Sexual differentiation of the zebra finch song system: potential roles for sex chromosome genes
Q37617712Shaping tubular carriers for intracellular membrane transport
Q37659792Shiga toxins--from cell biology to biomedical applications
Q37117850Snapin associates with late endocytic compartments and interacts with late endosomal SNAREs
Q37247436Some assembly required: putting the epithelial sodium channel together
Q42615643SorLA is a molecular link for retromer-dependent sorting of the Amyloid precursor protein
Q37980650Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins
Q41889248Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes
Q40103486Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.
Q38652662Sorting out release, uptake and processing of alpha-synuclein during prion-like spread of pathology
Q36610341Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis
Q33811885Souffle/Spastizin controls secretory vesicle maturation during zebrafish oogenesis.
Q91753611Spatiotemporal dissection of the trans-Golgi network in budding yeast
Q24309468Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways
Q27676909Structural basis of the strict phospholipid binding specificity of the pleckstrin homology domain of human evectin-2
Q43839416Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.
Q27649357Structure of Vps26B and mapping of its interaction with the retromer protein complex
Q38969723Subcellular localisation of retromer in post-endocytic pathways of polarised Madin-Darby canine kidney cells
Q30480503Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha.
Q34692456Syntaxin 16 regulates lumen formation during epithelial morphogenesis.
Q90730511System-Wide Characterization of MoArf GTPase Family Proteins and Adaptor Protein MoGga1 Involved in the Development and Pathogenicity of Magnaporthe oryzae
Q47035983TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi
Q36184859TGN38 is required for the metaphase I/anaphase I transition and asymmetric cell division during mouse oocyte meiotic maturation
Q24648200TIP47 functions in the biogenesis of lipid droplets
Q97069589TMEM16K is an interorganelle regulator of endosomal sorting
Q35268982TOSO, the Fcmicro receptor, is highly expressed on chronic lymphocytic leukemia B cells, internalizes upon IgM binding, shuttles to the lysosome, and is downregulated in response to TLR activation
Q30811916TSSC1 is novel component of the endosomal retrieval machinery
Q35659568Target silencing of components of the conserved oligomeric Golgi complex impairs HIV-1 replication
Q89088978The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology
Q37131468The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis
Q52601986The Arl3 and Arl1 GTPases co-operate with Cog8 to regulate selective autophagy via Atg9 trafficking.
Q40513377The Aspergillus nidulans syntaxin PepA(Pep12) is regulated by two Sec1/Munc-18 proteins to mediate fusion events at early endosomes, late endosomes and vacuoles
Q35156980The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport
Q47252697The Many Roles of Type II Phosphatidylinositol 4-Kinases in Membrane Trafficking: New Tricks for Old Dogs
Q77049440The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling
Q24336978The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway
Q30543691The Us2 gene product of herpes simplex virus 2 is a membrane-associated ubiquitin-interacting protein
Q30537081The adhesion modulation protein, AmpA localizes to an endocytic compartment and influences substrate adhesion, actin polymerization and endocytosis in vegetative Dictyostelium cells
Q34248085The complex ultrastructure of the endolysosomal system.
Q33638393The complexity of vesicle transport factors in plants examined by orthology search.
Q37635044The early endosome: a busy sorting station for proteins at the crossroads.
Q47222848The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.
Q37234777The endosomal system of plants: charting new and familiar territories.
Q30490954The function of the intermediate compartment in pre-Golgi trafficking involves its stable connection with the centrosome
Q36173925The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network
Q40413608The influenza A virus matrix protein 2 undergoes retrograde transport from the endoplasmic reticulum into the cytoplasm and bypasses cytoplasmic proteasomal degradation
Q90028569The interface between phosphatidylinositol transfer protein function and phosphoinositide signaling in higher eukaryotes
Q42832058The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles
Q33717079The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.
Q35083463The phospholipase A₂ enzyme complex PAFAH Ib mediates endosomal membrane tubule formation and trafficking
Q59129808The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis
Q28579110The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)
Q39552108The progressive ankylosis protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface
Q37863216The regulation of endosome-to-Golgi retrograde transport by tethers and scaffolds.
Q28115602The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting
Q24305115The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure
Q37308472Trafficking of receptor tyrosine kinases to the nucleus
Q50486365Trafficking of vacuolar proteins: the crucial role of Arabidopsis vacuolar protein sorting 29 in recycling vacuolar sorting receptor.
Q34777250Transport according to GARP: receiving retrograde cargo at the trans-Golgi network.
Q34020964Transport at the recycling endosome
Q36954877Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex
Q27931950Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.
Q35071617Type and composition of surfactants mediating gene transfection of polyethylenimine-coated liposomes
Q33664653Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells
Q34585020Uptake and processing of the cytolethal distending toxin by mammalian cells
Q37323348VPS10P-domain receptors - regulators of neuronal viability and function.
Q64110183VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation
Q33815889VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2.
Q36833749Vacuolar Sorting Receptor-Mediated Trafficking of Soluble Vacuolar Proteins in Plant Cells
Q48216129Valve interstitial cell culture: Production of mature type I collagen and precise detection.
Q35542711Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways
Q50332900Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
Q37145391Xenopus Wntless and the retromer complex cooperate to regulate XWnt4 secretion
Q40261959Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking
Q24322663Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution
Q36331590α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth

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