Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane

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Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBALIP.2010.08.001
P932PMC publication ID2957534
P698PubMed publication ID20713176
P5875ResearchGate publication ID45659490

P50authorYusuf A. HannunQ87620042
P2093author name stringDaniel Canals
Christopher J Clarke
Delphine Milhas
Jolanta Idkowiak-Baldys
P2860cites workNovel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored proteinQ24306630
Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignanciesQ24316872
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and GolgiQ28140190
Function of the cloned putative neutral sphingomyelinase as lyso-platelet activating factor-phospholipase CQ28141116
Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cellsQ28253449
The extended family of neutral sphingomyelinasesQ28264165
Principles of bioactive lipid signalling: lessons from sphingolipidsQ28265743
Neutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localizationQ28286272
Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and developmentQ28595054
Endocytic recyclingQ29547737
Ceramide triggers budding of exosome vesicles into multivesicular endosomesQ29616811
Retrograde transport from endosomes to the trans-Golgi networkQ29617826
The biogenesis of multivesicular endosomesQ29620561
Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptorsQ30487868
Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipidsQ33798777
Synthesis of the translational apparatus is regulated at the translational levelQ34058830
Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolismQ34174979
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosisQ34516496
Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.Q34579312
Bioactive sphingolipids: metabolism and functionQ34883222
Endocytic regulation of TGF-beta signalingQ34892916
Sustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent mannerQ34986708
Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cellsQ36322619
Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cellsQ36423828
Fluorescence-based methods to image palmitoylated proteinsQ36608782
New insights into membrane trafficking and protein sorting.Q36845704
Role of neutral sphingomyelinases in aging and inflammationQ37254333
TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesisQ37378533
Dynamic sequestration of the recycling compartment by classical protein kinase C.Q40271874
TNF-receptor I defective in internalization allows for cell death through activation of neutral sphingomyelinaseQ40288848
Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D.Q40569782
Internalization of cholera toxin by different endocytic mechanismsQ40768765
Nuclear localization of neutral sphingomyelinase 1: biochemical and immunocytochemical analyses.Q40768770
Importance of the carboxyl-terminal FTSL motif of membrane cofactor protein for basolateral sorting and endocytosis. Positive and negative modulation by signals inside and outside the cytoplasmic tailQ40944568
An essential role for autophosphorylation in the dissociation of activated protein kinase C from the plasma membraneQ41005441
Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sortingQ41233270
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptorsQ41522162
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liverQ42796730
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxisQ42805401
H-Ras does not need COP I- or COP II-dependent vesicular transport to reach the plasma membrane.Q42827129
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domainQ44075031
Ganglioside GM1 levels are a determinant of the extent of caveolae/raft-dependent endocytosis of cholera toxin to the Golgi apparatusQ44784002
Effect of harvesting methods, growth conditions and growth phase on diacylglycerol levels in cultured human adherent cellsQ68284414
Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometryQ79860458
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)1361-1374
P577publication date2010-08-14
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleAnterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane
P478volume1801

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cites work (P2860)
Q35130171A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization
Q55261326Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide.
Q26822419Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate
Q40796143Critical determinants of mitochondria-associated neutral sphingomyelinase (MA-nSMase) for mitochondrial localization
Q34089355Dynamic changes in the subcellular distribution of the tobacco ROS-producing enzyme RBOHD in response to the oomycete elicitor cryptogein
Q35063109Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference
Q35643759Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines
Q34734221Neutral sphingomyelinase in physiological and measles virus induced T cell suppression
Q34085972Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle
Q47110968Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane.
Q47872027Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes
Q39017698Regulation of exosome release by glycosphingolipids and flotillins
Q88938139Role of sphingolipids in the biogenesis and biological activity of extracellular vesicles
Q27022944Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes
Q38098404Sphingolipid metabolism and neutral sphingomyelinases
Q36422392Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis
Q92923604Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen
Q47844641Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation
Q92487187The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme
Q35055528The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes
Q37975165The roles of neutral sphingomyelinases in neurological pathologies
Q97536200Therapeutic Effects of Nano-HAp in a Rat Model of AlCl3 Induced Neurotoxicity

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