Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

scientific article

Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor is …
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scholarly articleQ13442814

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P356DOI10.1083/JCB.200312055
P8608Fatcat IDrelease_cfw7oywrtretbb46rvmrtflyce
P3181OpenCitations bibliographic resource ID552232
P932PMC publication ID2172094
P698PubMed publication ID15078903
P5875ResearchGate publication ID8623868

P50authorCecilia ArighiQ42423860
Juan S. BonifacinoQ50726280
P2093author name stringCarol R Haft
Lisa M Hartnell
Ruben C Aguilar
P2860cites workIdentification of a family of sorting nexin molecules and characterization of their association with receptorsQ22008017
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexesQ24290579
Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domainsQ24291292
TIP47: a cargo selection device for mannose 6-phosphate receptor traffickingQ24316494
Endosomal localization and function of sorting nexin 1Q24531264
Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1Q24531399
A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membraneQ24536667
Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrievalQ24555126
Distinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartmentQ24657977
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeastQ24670484
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cellsQ24671475
Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting proteinQ24672037
Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cellsQ24673272
Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35pQ24677799
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosomeQ24685974
GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complexQ24685976
BAR domains as sensors of membrane curvature: the amphiphysin BAR structureQ27642663
Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomesQ27931535
Adaptor complex-independent clathrin function in yeastQ27936498
Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.Q27938475
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 geneQ27939402
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene productsQ27939459
Yeast GGA proteins interact with GTP-bound Arf and facilitate transport through the GolgiQ28140794
Quantitative analysis of TIP47-receptor cytoplasmic domain interactions: implications for endosome-to-trans Golgi network traffickingQ28145311
Sorting of mannose 6-phosphate receptors mediated by the GGAsQ28198872
Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptorQ28198896
Self-assembly and binding of a sorting nexin to sorting endosomesQ28213235
Mannose 6-phosphate receptors: new twists in the taleQ28213265
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localizationQ28278951
Enhanced degradation of EGF receptors by a sorting nexin, SNX1Q28279650
Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liverQ28284882
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasisQ28505771
Syntaxin 6 functions in trans-Golgi network vesicle traffickingQ28572919
GGAs: roles of the different domains and comparison with AP-1 and clathrinQ28645806
The biogenesis of lysosomesQ29617860
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosisQ29618143
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomesQ29619337
mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsQ29622880
Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cellsQ30476964
Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi networkQ30477740
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomesQ31048369
A role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeastQ33938144
Structural requirements for function of yeast GGAs in vacuolar protein sorting, alpha-factor maturation, and interactions with clathrin.Q34012824
Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi networkQ34148158
Protein sorting into multivesicular endosomesQ34218897
Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: localization to the trans-Golgi network and recycling from the cell surface.Q34459118
Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesiclesQ34984669
Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidaseQ35399911
Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to thetrans-Golgi Network and a Subpopulation of Late EndosomesQ35802669
A quantitative analysis of the endocytic pathway in baby hamster kidney cellsQ36222043
Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartmentQ36255234
Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesiclesQ36289154
Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathwaysQ36301546
Yeast Gga coat proteins function with clathrin in Golgi to endosome transportQ37073871
A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptorQ37386983
A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranesQ38362519
The kinetics of mannose 6-phosphate receptor trafficking in the endocytic pathway in HEp-2 cells: the receptor enters and rapidly leaves multivesicular endosomes without accumulating in a prelysosomal compartmentQ38611087
Identification of the functional domains of yeast sorting nexins Vps5p and Vps17pQ39618296
Mu 1A deficiency induces a profound increase in MPR300/IGF-II receptor internalization rate.Q40756861
Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptorQ40817578
A determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomesQ41305610
Receptor extracellular domains may contain trafficking information. Studies of the 300-kDa mannose 6-phosphate receptorQ41473139
Possible pathways for lysosomal enzyme deliveryQ41494255
Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymQ41519880
Differences in the endosomal distributions of the two mannose 6-phosphate receptorsQ41551657
Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesiclesQ41582301
The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the GolgiQ41600770
Identification of subcellular compartments involved in biosynthetic processing of cathepsin DQ41609248
Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cellsQ41860842
Biosynthesis and turnover of the phosphomannosyl receptor in human fibroblastsQ42070674
Intracellular routing of transferrin and transferrin receptors in epidermoid carcinoma A431 cellsQ42453407
Acid hydrolases in early and late endosome fractions from rat liverQ46444634
Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptorQ50337363
The pathway of the asialoglycoprotein-ligand during receptor-mediated endocytosis: a morphological study with colloidal gold/ligand in the human hepatoma cell line, Hep G2Q70190721
Systematic mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor cytoplasmic domain. An acidic cluster containing a key aspartate is important for function in lysosomal enzyme sortingQ73119350
The 46-kDa mannose 6-phosphate receptor contains multiple binding sites for clathrin adaptorsQ73555548
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
VPS35 retromer complex componentQ21125246
VPS26, retromer complex component AQ21136427
P304page(s)123-33
P577publication date2004-04-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleRole of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
P478volume165

Reverse relations

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Q24304190SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors
Q35979194SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless
Q24300067SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment
Q37533162Sailing with the Wnt: charting the Wnt processing and secretion route
Q36775809Screening for VPS35 mutations in Parkinson's disease
Q37636981Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stro
Q47765002Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Q35663393Some, but not all, retromer components promote morphogenesis of C. elegans sensory compartments
Q42615643SorLA is a molecular link for retromer-dependent sorting of the Amyloid precursor protein
Q40103486Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.
Q30047766Sorting in early endosomes reveals connections to docking- and fusion-associated factors
Q89636089Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery
Q36798625Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth
Q24318810Sorting nexin 8 regulates endosome-to-Golgi transport
Q24308072Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides
Q24682101Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport
Q46604079Sorting nexins 1 and 2a locate mainly to the TGN.
Q37970882Sorting nexins provide diversity for retromer-dependent trafficking events
Q36000866Sorting nexins--unifying trends and new perspectives
Q36003848Sorting of the yeast vacuolar-type, proton-translocating ATPase enzyme complex (V-ATPase): identification of a necessary and sufficient Golgi/endosomal retention signal in Stv1p
Q38652662Sorting out release, uptake and processing of alpha-synuclein during prion-like spread of pathology
Q36610341Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis
Q50260233Structural Mechanism for Cargo Recognition by the Retromer Complex.
Q89700524Structural and functional insights into sorting nexin 5/6 interaction with bacterial effector IncE
Q37408680Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.
Q36824414Structural features of vps35p involved in interaction with other subunits of the retromer complex
Q27649357Structure of Vps26B and mapping of its interaction with the retromer protein complex
Q38176243Study of GOLPH3: a potential stress-inducible protein from Golgi apparatus
Q38969723Subcellular localisation of retromer in post-endocytic pathways of polarised Madin-Darby canine kidney cells
Q26781334Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors
Q34991404Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction
Q24648200TIP47 functions in the biogenesis of lipid droplets
Q47112563Taking out the garbage: cathepsin D and calcineurin in neurodegeneration.
Q50729583Targeting of the plant vacuolar sorting receptor BP80 is dependent on multiple sorting signals in the cytosolic tail.
Q36709124The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to the Schwann cell cytoplasm and endomembrane compartments, where they depend upon each other to achieve wild-type levels of protein expression
Q51172931The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking.
Q99726049The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders
Q36961170The Salmonella-containing vacuole: moving with the times
Q38093808The VPS35 gene and Parkinson's disease
Q24301952The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics
Q24294707The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step
Q28115999The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain
Q37635044The early endosome: a busy sorting station for proteins at the crossroads.
Q47217972The emerging role of Rab GTPases in the pathogenesis of Parkinson's disease
Q39235096The emerging role of retromer in neuroprotection
Q47222848The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.
Q37234777The endosomal system of plants: charting new and familiar territories.
Q89449412The enigmatic endosome - sorting the ins and outs of endocytic trafficking
Q47324789The functional roles of retromer in Parkinson's disease
Q34786749The giardial VPS35 retromer subunit is necessary for multimeric complex assembly and interaction with the vacuolar protein sorting receptor
Q36173925The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network
Q24669939The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide
Q92382659The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases
Q30537229The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport
Q41944297The luminal domain participates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor
Q24301637The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.
Q24299142The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor
Q34076263The march of the PINs: developmental plasticity by dynamic polar targeting in plant cells
Q41711908The multiple roles of Rab9 in the endolysosomal system
Q37863216The regulation of endosome-to-Golgi retrograde transport by tethers and scaffolds.
Q24316171The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network
Q26866457The retromer complex - endosomal protein recycling and beyond
Q26801164The retromer complex in development and disease
Q24305021The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network
Q24321279The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport
Q24673655The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain
Q35840011The role of cargo proteins in GGA recruitment
Q28115602The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting
Q24310050The ubiquitin ligase RNF126 regulates the retrograde sorting of the cation-independent mannose 6-phosphate receptor
Q24293671The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling
Q58586107This Is the End: Regulation of Rab7 Nucleotide Binding in Endolysosomal Trafficking and Autophagy
Q91336361To degrade or not to degrade: mechanisms and significance of endocytic recycling
Q36161695Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks
Q50486365Trafficking of vacuolar proteins: the crucial role of Arabidopsis vacuolar protein sorting 29 in recycling vacuolar sorting receptor.
Q34020964Transport at the recycling endosome
Q52319318Tying Trafficking to Fusion and Fission at the Mighty Mitochondria.
Q63384325USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
Q50726204Ultrastructure of long-range transport carriers moving from the trans Golgi network to peripheral endosomes.
Q36796400Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
Q41572903Updated Insight into the Physiological and Pathological Roles of the Retromer Complex
Q24298162VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface
Q28478267VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins
Q53520639VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.
Q50325266VPS35 depletion does not impair presynaptic structure and function.
Q35670733VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.
Q35103751VPS35 mutations in Parkinson disease
Q36468331VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1
Q92537195VPS35-Based Approach: A Potential Innovative Treatment in Parkinson's Disease
Q36833749Vacuolar Sorting Receptor-Mediated Trafficking of Soluble Vacuolar Proteins in Plant Cells
Q42065653Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson's disease mutant of Leucine-Rich Repeat Kinase 2 (LRRK2).
Q53641473Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2.
Q28257489Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
Q37323063WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors
Q37131503WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion
Q38719156Where no Ras has gone before: VPS35 steers N-Ras through the cytosol.
Q37282120Wortmannin induces homotypic fusion of plant prevacuolar compartments

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