A determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomes

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A determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomes is …
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scholarly articleQ13442814

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P356DOI10.1083/JCB.130.6.1297
P8608Fatcat IDrelease_i3te5pv3i5aifal4taqq5hjqz4
P932PMC publication ID2120581
P698PubMed publication ID7559753
P5875ResearchGate publication ID277398015

P2093author name stringA Schweizer
J Rohrer
S Kornfeld
K F Johnson
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domainQ24556506
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatusQ24679792
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Lysosomal targeting of Limp II membrane glycoprotein requires a novel Leu-Ile motif at a particular position in its cytoplasmic tailQ28249491
The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomesQ28285769
Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycanQ28291400
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi networkQ28609803
Rab9 functions in transport between late endosomes and the trans Golgi networkQ28609814
Targeting of membrane proteins to endosomes and lysosomesQ28612146
The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomesQ30442254
Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.Q33636477
The mannose 6-phosphate receptor cytoplasmic domain is not sufficient to alter the cellular distribution of a chimeric EGF receptorQ33916617
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptorsQ34236758
Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteinsQ36217696
Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tailQ36223847
Identification of a novel, N-ethylmaleimide-sensitive cytosolic factor required for vesicular transport from endosomes to the trans-Golgi network in vitroQ36529347
Low density lipoprotein receptor and cation-independent mannose 6-phosphate receptor are transported from the cell surface to the Golgi apparatus at equal rates in PC12 cellsQ36531164
Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targetingQ37603016
A tyrosine-containing motif mediates ER retention of CD3-epsilon and adopts a helix-turn structure.Q40806744
Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes.Q41229177
Receptor extracellular domains may contain trafficking information. Studies of the 300-kDa mannose 6-phosphate receptorQ41473139
A chimera of the cytoplasmic tail of the mannose 6-phosphate/IGF-II receptor and lysozyme localizes to the TGN rather than prelysosomes where the bulk of the endogenous receptor is found.Q41477277
Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymQ41519880
Tail-specific antibodies that block return of 46,000 M(r) mannose 6-phosphate receptor to the trans-Golgi networkQ41540544
Differences in the endosomal distributions of the two mannose 6-phosphate receptorsQ41551657
Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatusQ41563890
The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the GolgiQ41600770
A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting functionQ41607768
Localization of the signal for rapid internalization of the bovine cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor to amino acids 24-29 of the cytoplasmic tailQ41690827
Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitroQ41730580
Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitroQ46562898
Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptorQ50337363
Characterization of protein transport between successive compartments of the Golgi apparatus: asymmetric properties of donor and acceptor activities in a cell-free system.Q54448204
Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosisQ69348661
Studies of the biosynthesis of the cation-dependent mannose 6-phosphate receptor in murine cell linesQ70037318
The mannose receptor and the cation-dependent form of mannose 6-phosphate receptor have overlapping cellular and subcellular distributions in liverQ72545203
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1297-1306
P577publication date1995-09-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleA determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomes
P478volume130

Reverse relations

cites work (P2860)
Q30602571A di-aromatic motif in the cytosolic tail of the mannose receptor mediates endosomal sorting
Q34022650A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone.
Q45936193A novel assay reveals a role for soluble N-ethylmaleimide-sensitive fusion attachment protein in mannose 6-phosphate receptor transport from endosomes to the trans Golgi network.
Q43721267Access of a membrane protein to secretory granules is facilitated by phosphorylation
Q36255053Aggregation as a determinant of protein fate in post-Golgi compartments: role of the luminal domain of furin in lysosomal targeting
Q40781162Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
Q40923003Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis
Q28191321Characterization of the Endosomal Sorting Signal of the Cation-dependent Mannose 6-Phosphate Receptor
Q36301546Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways
Q24628984Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells
Q24292167Cloning and characterization of a lysosomal phospholipase A2, 1-O-acylceramide synthase
Q48050460Cloning and subcellular location of an Arabidopsis receptor-like protein that shares common features with protein-sorting receptors of eukaryotic cells
Q41233270Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sorting
Q41915571Distribution and trafficking of MPR300 is normal in cells with cholesterol accumulated in late endocytic compartments: evidence for early endosome-to-TGN trafficking of MPR300.
Q28578966Efficient trafficking of TGN38 from the endosome to the trans-Golgi network requires a free hydroxyl group at position 331 in the cytosolic domain
Q29547737Endocytic recycling
Q22254028Function and properties of chimeric MPR 46-MPR 300 mannose 6-phosphate receptors
Q33783423Herpes simplex virus gD and virions accumulate in endosomes by mannose 6-phosphate-dependent and -independent mechanisms.
Q28237909Immunocytochemical localization of the Menkes copper transport protein (ATP7A) to the trans-Golgi network
Q73745130Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion
Q24634104Lysosomal hydrolase mannose 6-phosphate uncovering enzyme resides in the trans-Golgi network
Q28282060Lysosomal targeting of palmitoyl-protein thioesterase
Q24320100Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity
Q36255234Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment
Q37351642Palmitoylation of membrane proteins (Review).
Q40941477Phosphorylation of cytosolic domain Ser(937) affects both biosynthetic and endocytic trafficking of peptidylglycine alpha-amidating monooxygenase
Q36820853Proper sorting of the cation-dependent mannose 6-phosphate receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail
Q36237576Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components
Q24559952Rab9 GTPase regulates late endosome size and requires effector interaction for its stability
Q40813493Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH.
Q34678178Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
Q24336478Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
Q43946084Routing of membrane proteins to large dense core vesicles in PC12 cells
Q30495517Secretory granule membrane protein recycles through multivesicular bodies
Q40243441Serine phosphorylation site of the 46-kDa mannose 6-phosphate receptor is required for transport to the plasma membrane in Madin-Darby canine kidney and mouse fibroblast cells
Q40990944Stabilization of mutant 46-kDa mannose 6-phosphate receptors by proteasomal inhibitor lactacystin
Q37214274Strategies for carbohydrate recognition by the mannose 6-phosphate receptors
Q24316494TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking
Q40573543The acidic cluster of the CK2 site of the cation-dependent mannose 6-phosphate receptor (CD-MPR) but not its phosphorylation is required for GGA1 and AP-1 binding
Q34359076The palmitoyltransferase of the cation-dependent mannose 6-phosphate receptor cycles between the plasma membrane and endosomes
Q24651864The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane
Q35909761The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesicles
Q28610251Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells
Q30478406Transition of galactosyltransferase 1 from trans-Golgi cisterna to the trans-Golgi network is signal mediated

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