Uptake and processing of the cytolethal distending toxin by mammalian cells

scientific article

Uptake and processing of the cytolethal distending toxin by mammalian cells is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/TOXINS6113098
P932PMC publication ID4247254
P698PubMed publication ID25365527
P5875ResearchGate publication ID267753754

P2093author name stringJoseph M DiRienzo
P2860cites workCoupling of coat assembly and vesicle budding to packaging of putative cargo receptorsQ22008843
Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinaseQ22254143
Interaction of a Golgi-associated kinesin-like protein with Rab6Q24322499
Haploid genetic screens in human cells identify host factors used by pathogensQ24336198
RetromerQ24632869
The pertussis toxin S1 subunit is a thermally unstable protein susceptible to degradation by the 20S proteasomeQ24642842
Mutations in human dynamin block an intermediate stage in coated vesicle formationQ24674406
Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent processQ24675885
Tyrosine sulfation is a trans-Golgi-specific protein modificationQ24680180
The Sec-dependent pathwayQ27010633
Structure and function of the Salmonella Typhi chimaeric A2B5 typhoid toxinQ27679027
Nuclear targeting sequences--a consensus?Q27860997
Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesiclesQ27939177
Nuclear targeting of proteins: how many different signals?Q28144950
Nuclear protein localizationQ29397060
The mechanisms of vesicle budding and fusionQ29615234
The complete general secretory pathway in gram-negative bacteriaQ29615298
Lipid rafts as a membrane-organizing principleQ29615727
Dynamin self-assembles into rings suggesting a mechanism for coated vesicle buddingQ29616586
Retrograde transport from endosomes to the trans-Golgi networkQ29617826
Characterization of point mutations in the cdtA gene of the cytolethal distending toxin of Actinobacillus actinomycetemcomitansQ33227996
Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxinQ33239764
Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuniQ33511033
Carbohydrate-binding specificity of the Escherichia coli cytolethal distending toxin CdtA-II and CdtC-II subunitsQ33769251
Organization of the ER-Golgi interface for membrane traffic controlQ33779916
Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterolQ33897702
Golgi compartmentation and identityQ34036999
GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furinQ34107128
Dynamin and endocytosisQ34154738
Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricinQ34186098
Assembly and function of a bacterial genotoxinQ34323135
Maturation steps of the Salmonella-containing vacuole.Q34469828
Functional studies of the recombinant subunits of a cytolethal distending holotoxinQ34536377
Cytolethal distending toxin: limited damage as a strategy to modulate cellular functionsQ34543559
Trafficking of the Salmonella vacuole in macrophagesQ34557132
Lipoproteins in bacteriaQ34660581
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and virusesQ35031738
Global gene disruption in human cells to assign genes to phenotypes by deep sequencingQ35036768
Evidence that the transport of ricin to the cytoplasm is independent of both Rab6A and COPI.Q51835354
The retromer complex and clathrin define an early endosomal retrograde exit site.Q54485120
Actinobacillus actinomycetemcomitans cytolethal distending toxin (Cdt): evidence that the holotoxin is composed of three subunits: CdtA, CdtB, and CdtC.Q54513363
Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex.Q54605902
Cytolethal Distending Toxin: A Unique Variation on the AB Toxin ParadigmQ59072627
Is CdtB a nuclease or a phosphatase?Q73398550
The role of different protein components from the Haemophilus ducreyi cytolethal distending toxin in the generation of cell toxicityQ73999036
Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus patternQ77614441
Comparative structure-function analysis of cytolethal distending toxinsQ81521844
Physiology and pathology of endosome-to-Golgi retrograde sortingQ35097982
Cholesterol depletion reduces entry of Campylobacter jejuni cytolethal distending toxin and attenuates intoxication of host cellsQ35191867
Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entryQ35215974
Perinuclear localization of internalized outer membrane vesicles carrying active cytolethal distending toxin from Aggregatibacter actinomycetemcomitansQ35665388
Delivery into cells: lessons learned from plant and bacterial toxinsQ36091291
Localization of Aggregatibacter actinomycetemcomitans cytolethal distending toxin subunits during intoxication of live cellsQ36211167
Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transportQ36255884
Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitansQ36458204
Cellular interactions of the cytolethal distending toxins from Escherichia coli and Haemophilus ducreyiQ36685128
Role of aromatic amino acids in receptor binding activity and subunit assembly of the cytolethal distending toxin of Aggregatibacter actinomycetemcomitansQ36747160
Retrograde traffic from the Golgi to the endoplasmic reticulumQ36865153
Exiting the Golgi complexQ37114569
Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathwayQ37358294
Tracing the retrograde route in protein trafficking.Q37358575
The retromer complexQ37629938
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicineQ37729388
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulumQ37954281
The biology of the cytolethal distending toxinsQ37954328
Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxinsQ38037553
Retrograde transport of protein toxins through the Golgi apparatusQ38114338
Cellular internalization of cytolethal distending toxin from Haemophilus ducreyiQ39517342
Structural characteristics of the plasmid-encoded toxin from enteroaggregative Escherichia coliQ39950787
Delivery of a Salmonella Typhi exotoxin from a host intracellular compartmentQ40025777
In vitro reconstitution of ARF-regulated cytoskeletal dynamics on Golgi membranes.Q40358087
Cellular internalization of cytolethal distending toxin: a new end to a known pathwayQ40410422
A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like proteinQ40849335
Signal transduction by cholera toxin: processing in vesicular compartments does not require acidificationQ41292469
How proteins are transported from cytoplasm to the nucleusQ41506849
Biogenesis of the Actinobacillus actinomycetemcomitans cytolethal distending toxin holotoxinQ41832969
Conformational instability of the cholera toxin A1 polypeptideQ41835060
Involvement of ganglioside GM3 in G(2)/M cell cycle arrest of human monocytic cells induced by Actinobacillus actinomycetemcomitans cytolethal distending toxinQ41848550
A novel mode of translocation for cytolethal distending toxinQ42102805
Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterolQ43147171
Scyl1 scaffolds class II Arfs to specific subcomplexes of coatomer through the γ-COP appendage domain.Q43598915
An N-terminal segment of the active component of the bacterial genotoxin cytolethal distending toxin B (CDTB) directs CDTB into the nucleusQ44567843
Nuclear localization of the Escherichia coli cytolethal distending toxin CdtB subunitQ44823819
Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulumQ45345946
DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrestQ45398278
Cholesterol homeostasis in T cells. Methyl-beta-cyclodextrin treatment results in equal loss of cholesterol from Triton X-100 soluble and insoluble fractionsQ46676190
Detection and functionality of the CdtB, PltA, and PltB from Salmonella enterica serovar JavianaQ49996974
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcellQ7868
nucleusQ40260
bacterial proteinQ64923821
biomedical investigative techniqueQ66648976
P304page(s)3098-3116
P577publication date2014-10-31
P1433published inToxinsQ15724569
P1476titleUptake and processing of the cytolethal distending toxin by mammalian cells
P478volume6

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cites work (P2860)
Q26738908A Journey of Cytolethal Distending Toxins through Cell Membranes
Q92881318Bacterial Genotoxin-Induced DNA Damage and Modulation of the Host Immune Microenvironment
Q26798188Bacterial Genotoxins: Merging the DNA Damage Response into Infection Biology
Q64109014Cell transfection of purified cytolethal distending toxin B subunits allows comparing their nuclease activity while plasmid degradation assay does not
Q89757750Cytolethal distending toxin-induced release of interleukin-1β by human macrophages is dependent upon activation of glycogen synthase kinase 3β, spleen tyrosine kinase (Syk) and the noncanonical inflammasome
Q26749361Dynamic Duo-The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin
Q64085033Genome-Wide Identification of Host Genes Required for Toxicity of Bacterial Cytolethal Distending Toxin in a Yeast Model
Q36270087Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury
Q26739669Impact of CDT Toxin on Human Diseases
Q97521594Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (Synaptogyrin-2)
Q37835828Subversion of host genome integrity by bacterial pathogens
Q37530444The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi
Q92127105Tools of Aggregatibacter actinomycetemcomitans to Evade the Host Response
Q91808199Transcriptomic Analysis of Aggregatibacter actinomycetemcomitans Core and Accessory Genes in Different Growth Conditions

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