review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Xiang Wang | |
Haoxing Xu | |||
Dongbiao Shen | |||
P2860 | cites work | PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane. | Q55038004 |
Endosome-lysosome fusion. | Q55053647 | ||
Luminal chloride-dependent activation of endosome calcium channels: patch clamp study of enlarged endosomes | Q80563733 | ||
Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids | Q82616680 | ||
NAADP as an intracellular messenger regulating lysosomal calcium-release channels | Q82669208 | ||
Neurotransmitter Release | Q22337388 | ||
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex | Q24307982 | ||
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy | Q24318098 | ||
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse | Q24318746 | ||
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion | Q24322668 | ||
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release | Q24611697 | ||
The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice | Q24618677 | ||
Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase | Q24643186 | ||
Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease | Q24645601 | ||
Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent | Q24678109 | ||
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice. | Q24678783 | ||
The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover | Q24683845 | ||
Phosphoinositides in cell regulation and membrane dynamics | Q27861051 | ||
Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p | Q27930743 | ||
Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion. | Q27935567 | ||
Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors | Q27936381 | ||
Internal Ca(2+) release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue | Q27938797 | ||
A role for calcium in stabilizing transport vesicle coats. | Q43660573 | ||
A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. | Q43798608 | ||
pH-dependent regulation of lysosomal calcium in macrophages | Q43893449 | ||
Selective effects of calcium chelators on anterograde and retrograde protein transport in the cell. | Q44061987 | ||
Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2. | Q44200822 | ||
Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells. | Q50777337 | ||
Mechanical force and cytoplasmic Ca(2+) activate yeast TRPY1 in parallel. | Q51819658 | ||
SNAREpins: minimal machinery for membrane fusion | Q28131697 | ||
Rab GTPases as coordinators of vesicle traffic | Q28131746 | ||
Translation of the phosphoinositide code by PI effectors | Q28285651 | ||
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel | Q28294133 | ||
Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis | Q28486859 | ||
Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes | Q28511012 | ||
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J | Q28511673 | ||
Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes | Q28572060 | ||
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome | Q29543488 | ||
Regulation mechanisms and signaling pathways of autophagy | Q29547416 | ||
Endocytic recycling | Q29547737 | ||
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Q29614500 | ||
Retrograde transport from endosomes to the trans-Golgi network | Q29617826 | ||
The emerging shape of the ESCRT machinery | Q29620787 | ||
Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting. | Q30478189 | ||
Small molecule activators of TRPML3 | Q33535026 | ||
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. | Q33826723 | ||
Mucolipins: Intracellular TRPML1-3 channels | Q33838349 | ||
TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP | Q33840138 | ||
Lysosome-endosome fusion and lysosome biogenesis. | Q33883540 | ||
HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly | Q33948566 | ||
TRP channels of intracellular membranes | Q34001734 | ||
Phosphoinositides function asymmetrically for membrane fusion, promoting tethering and 3Q-SNARE subcomplex assembly | Q34386086 | ||
Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts | Q34427650 | ||
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis | Q34446025 | ||
The lysosome turns fifty | Q34447595 | ||
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes | Q34478343 | ||
Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels | Q34512579 | ||
Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs | Q34657408 | ||
Phagosome maturation: aging gracefully | Q34682299 | ||
Mechanisms of membrane fusion: disparate players and common principles. | Q34780589 | ||
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium | Q34866369 | ||
Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS. | Q34913669 | ||
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function | Q34959368 | ||
Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes | Q34990714 | ||
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. | Q35005794 | ||
Regulation of presynaptic calcium channels by synaptic proteins | Q35165594 | ||
Calcium and calmodulin in membrane fusion | Q35197974 | ||
Calcium: a fundamental regulator of intracellular membrane fusion? | Q35658408 | ||
Phosphoinositides in constitutive membrane traffic. | Q35842974 | ||
Cell biology of mycobacterium tuberculosis phagosome. | Q35912811 | ||
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway | Q36320962 | ||
Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lumen | Q36322360 | ||
Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest | Q36377580 | ||
Mutations in phosphoinositide metabolizing enzymes and human disease | Q36402106 | ||
Regulation of epithelial ion channels by Rab GTPases | Q36644799 | ||
Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion | Q36790508 | ||
Autophagic dysfunction in mucolipidosis type IV patients | Q36835710 | ||
Lysosomes: fusion and function | Q36885390 | ||
PIP2 is a necessary cofactor for ion channel function: how and why? | Q37197976 | ||
Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca(2+) homeostasis | Q37219948 | ||
Function and dysfunction of the PI system in membrane trafficking. | Q37266145 | ||
Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis | Q37357908 | ||
Phosphatidylinositol metabolism and membrane fusion | Q37386315 | ||
Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1. | Q37479337 | ||
Tethering factors as organizers of intracellular vesicular traffic | Q37540143 | ||
Cholesterol involvement in the pathogenesis of neurodegenerative diseases. | Q37574307 | ||
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes | Q37606853 | ||
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria | Q37732047 | ||
Lysosomal storage disease: revealing lysosomal function and physiology. | Q37739706 | ||
Membrane fusion: five lipids, four SNAREs, three chaperones, two nucleotides, and a Rab, all dancing in a ring on yeast vacuoles | Q37762546 | ||
Endolysosomal calcium regulation and disease | Q37813734 | ||
TRPM2 functions as a lysosomal Ca2+-release channel in beta cells | Q39849413 | ||
Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic | Q40231477 | ||
Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles | Q40293294 | ||
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism | Q40531614 | ||
Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes. | Q40635710 | ||
Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity | Q40980700 | ||
Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells. | Q42254064 | ||
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles. | Q42823479 | ||
Calcium uptake via endocytosis with rapid release from acidifying endosomes. | Q42823932 | ||
The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles | Q42919564 | ||
Regulation of PIKfyve phosphorylation by insulin and osmotic stress | Q43049902 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 448-457 | |
P577 | publication date | 2011-04-28 | |
P1433 | published in | BioEssays | Q4914614 |
P1476 | title | Pairing phosphoinositides with calcium ions in endolysosomal dynamics: phosphoinositides control the direction and specificity of membrane trafficking by regulating the activity of calcium channels in the endolysosomes | |
P478 | volume | 33 |
Q38359528 | A New Perspective of Lysosomal Cation Channel-Dependent Homeostasis in Alzheimer's Disease |
Q37224430 | A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis |
Q90074289 | Abnormal Lysosomal Positioning and Small Extracellular Vesicle Secretion in Arterial Stiffening and Calcification of Mice Lacking Mucolipin 1 Gene |
Q37557563 | Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes |
Q38202209 | Ca(2+) signals, NAADP and two-pore channels: role in cellular differentiation |
Q35771431 | Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion |
Q38620889 | Calcium signaling in membrane repair |
Q26824526 | Congenital myopathies: an update |
Q30560982 | Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics |
Q36063560 | HIV Assembly and Budding: Ca(2+) Signaling and Non-ESCRT Proteins Set the Stage |
Q42093777 | Hormone-stimulated modulation of endocytic trafficking in osteoclasts |
Q30537817 | Intracellular two-phase Ca2+ release and apoptosis controlled by TRP-ML1 channel activity in coronary arterial myocytes |
Q41822869 | Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release |
Q64104278 | Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc |
Q33653667 | Lysosomal exocytosis and lipid storage disorders |
Q34462083 | Lysosomal physiology |
Q40164611 | Mechanisms of Filovirus Entry. |
Q59354303 | NAADP-dependent Ca signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system |
Q36595827 | PIPing on lysosome tubes |
Q89920236 | Podocyte Lysosome Dysfunction in Chronic Glomerular Diseases |
Q37409739 | Regulation of mTORC1 by lysosomal calcium and calmodulin. |
Q38123475 | Regulation of membrane trafficking by signalling on endosomal and lysosomal membranes |
Q28276964 | TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes |
Q47224732 | The lysosomal Ca2+ release channel TRPML1 regulates lysosome size by activating calmodulin |
Q26849317 | Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine |
Q33703425 | Two-Pore Channels and Parkinson's Disease: Where's the Link? |
Q37613806 | Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions |
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